IMP

Process View

Homo sapiens

10 genes annotated in human

female gonad development

The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "female gonad development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "female gonad development" (in gray)

Name	Description	Probability	Func Analog Organism
BCL2	B-cell CLL/lymphoma 2	0.951	Mouse Rat
INSR	insulin receptor	0.941	Fly
ESR1	estrogen receptor 1	0.761	Mouse
EGFR	epidermal growth factor receptor	0.742
TP53	tumor protein p53	0.626
NRP1	neuropilin 1	0.541
POU5F1	POU class 5 homeobox 1	0.540
BCL2L1	BCL2-like 1	0.381	Mouse Rat
VEGFA	vascular endothelial growth factor A	0.374	Mouse
GRB10	growth factor receptor-bound protein 10	0.321
BCAR1	breast cancer anti-estrogen resistance 1	0.305
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.291
IRS1	insulin receptor substrate 1	0.289
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.249
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.246
TEK	TEK tyrosine kinase, endothelial	0.230
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.216
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.207
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.171	Mouse
PDX1	pancreatic and duodenal homeobox 1	0.147
HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	0.143
CDK2	cyclin-dependent kinase 2	0.128
PLAU	plasminogen activator, urokinase	0.117
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.103
TDGF1	teratocarcinoma-derived growth factor 1	0.097
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.096
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.090
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.074
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.074
ZNF512B	zinc finger protein 512B	0.073
IRS2	insulin receptor substrate 2	0.071
FSTL1	follistatin-like 1	0.068
NCOR2	nuclear receptor corepressor 2	0.066
EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	0.065
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.065
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.063
JAK2	Janus kinase 2	0.063
NF2	neurofibromin 2 (merlin)	0.061
MPDZ	multiple PDZ domain protein	0.061
BAK1	BCL2-antagonist/killer 1	0.055
TGFB1	transforming growth factor, beta 1	0.053
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.053
NCOA2	nuclear receptor coactivator 2	0.052
STAT5A	signal transducer and activator of transcription 5A	0.051	Mouse
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.049	Mouse
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.049
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.047
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.043
TIMP2	TIMP metallopeptidase inhibitor 2	0.042
E2F1	E2F transcription factor 1	0.042
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.040
PRKCA	protein kinase C, alpha	0.040	Fly
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.039
PCGF2	polycomb group ring finger 2	0.037
CPE	carboxypeptidase E	0.036
FANCE	Fanconi anemia, complementation group E	0.036
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.035
IGF1R	insulin-like growth factor 1 receptor	0.035	Fly
FANCD2	Fanconi anemia, complementation group D2	0.035
TMSB4X	thymosin beta 4, X-linked	0.033
RNR2	l-rRNA	0.033
CSNK1D	casein kinase 1, delta	0.032
HDAC6	histone deacetylase 6	0.031
AR	androgen receptor	0.030
BRCA2	breast cancer 2, early onset	0.029	Mouse
GAB1	GRB2-associated binding protein 1	0.029
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.028
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.028
FANCC	Fanconi anemia, complementation group C	0.028
NEUROD1	neurogenic differentiation 1	0.027
EIF2B5	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa	0.027
FOXO1	forkhead box O1	0.027
MYLK2	myosin light chain kinase 2	0.026
ARNT	aryl hydrocarbon receptor nuclear translocator	0.026
FASLG	Fas ligand (TNF superfamily, member 6)	0.025
RNF144B	ring finger protein 144B	0.024
NCF1	neutrophil cytosolic factor 1	0.024
VEGFC	vascular endothelial growth factor C	0.022
NCOA1	nuclear receptor coactivator 1	0.022
PGF	placental growth factor	0.022
BMP2	bone morphogenetic protein 2	0.021
BID	BH3 interacting domain death agonist	0.021
GDF5	growth differentiation factor 5	0.021
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.021
RBMX	RNA binding motif protein, X-linked	0.021
EP300	E1A binding protein p300	0.021
PPP5C	protein phosphatase 5, catalytic subunit	0.021
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.020
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.020
RBPMS	RNA binding protein with multiple splicing	0.019
SP1	Sp1 transcription factor	0.019
DAXX	death-domain associated protein	0.019
ACTB	actin, beta	0.018
HNRNPL	heterogeneous nuclear ribonucleoprotein L	0.018
EIF2B2	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa	0.018
HES1	hairy and enhancer of split 1, (Drosophila)	0.018
WT1	Wilms tumor 1	0.017	Mouse
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.016
IGSF21	immunoglobin superfamily, member 21	0.016
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.016
JDP2	Jun dimerization protein 2	0.015
FADD	Fas (TNFRSF6)-associated via death domain	0.015
NCOA6	nuclear receptor coactivator 6	0.015
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.015
INHBA	inhibin, beta A	0.015
PLAT	plasminogen activator, tissue	0.015
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.015
FGFR2	fibroblast growth factor receptor 2	0.015
CDH5	cadherin 5, type 2 (vascular endothelium)	0.015
THBS2	thrombospondin 2	0.015
PPARA	peroxisome proliferator-activated receptor alpha	0.014
RAD23B	RAD23 homolog B (S. cerevisiae)	0.014
SYCP3	synaptonemal complex protein 3	0.014
A2M	alpha-2-macroglobulin	0.014
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.014
FGF10	fibroblast growth factor 10	0.014
TRRAP	transformation/transcription domain-associated protein	0.014
ESR2	estrogen receptor 2 (ER beta)	0.014	Rat
SFN	stratifin	0.014
LAT	linker for activation of T cells	0.013
CAV1	caveolin 1, caveolae protein, 22kDa	0.013
PLCG1	phospholipase C, gamma 1	0.013
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.013
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.013
TOP1	topoisomerase (DNA) I	0.012
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.012
CCND1	cyclin D1	0.012
TIMP3	TIMP metallopeptidase inhibitor 3	0.012
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.012
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.012
ACACA	acetyl-CoA carboxylase alpha	0.012
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.011
PABPC1	poly(A) binding protein, cytoplasmic 1	0.011
KAT2B	K(lysine) acetyltransferase 2B	0.011
NCOR1	nuclear receptor corepressor 1	0.011
FOXC1	forkhead box C1	0.011	Human Mouse
TAF12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa	0.011
FTSJ3	FtsJ homolog 3 (E. coli)	0.011
TRIM9	tripartite motif containing 9	0.011
EPAS1	endothelial PAS domain protein 1	0.010
FST	follistatin	0.010	Mouse
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.010	Fly
NDP	Norrie disease (pseudoglioma)	0.010
SSTR3	somatostatin receptor 3	0.010