IMP

Process View

Homo sapiens

1 genes annotated in human

trachea development

The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "trachea development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "trachea development" (in gray)

Name	Description	Probability	Func Analog Organism
FGF1	fibroblast growth factor 1 (acidic)	0.822
BMPR1A	bone morphogenetic protein receptor, type IA	0.334
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.220
RXRA	retinoid X receptor, alpha	0.176
JUB	jub, ajuba homolog (Xenopus laevis)	0.157
EGLN1	egl nine homolog 1 (C. elegans)	0.126
TSC2	tuberous sclerosis 2	0.115
JUN	jun proto-oncogene	0.113
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.109
DAXX	death-domain associated protein	0.103
STRN4	striatin, calmodulin binding protein 4	0.100
TGFB1	transforming growth factor, beta 1	0.093
YAP1	Yes-associated protein 1	0.083
EZR	ezrin	0.080
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.061
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.059	Fly
FUNDC2	FUN14 domain containing 2	0.057
MKL1	megakaryoblastic leukemia (translocation) 1	0.056
SMAD3	SMAD family member 3	0.055
ZFYVE9	zinc finger, FYVE domain containing 9	0.054
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.054
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.052	Fly
FSTL1	follistatin-like 1	0.052
EGLN3	egl nine homolog 3 (C. elegans)	0.050
CTTNBP2NL	CTTNBP2 N-terminal like	0.050
NCOA1	nuclear receptor coactivator 1	0.047
OCLN	occludin	0.045
ARNT	aryl hydrocarbon receptor nuclear translocator	0.044
EPAS1	endothelial PAS domain protein 1	0.044	Fly
AMOT	angiomotin	0.042
PPP6C	protein phosphatase 6, catalytic subunit	0.042
KIAA1377	KIAA1377	0.039
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.039
MYOCD	myocardin	0.037
GSK3B	glycogen synthase kinase 3 beta	0.036
FAM40B	family with sequence similarity 40, member B	0.035
SNAI1	snail homolog 1 (Drosophila)	0.035
FGF10	fibroblast growth factor 10	0.035
MED25	mediator complex subunit 25	0.035
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.034
PDCD6IP	programmed cell death 6 interacting protein	0.033
STK3	serine/threonine kinase 3	0.033
STK4	serine/threonine kinase 4	0.033
TGFB3	transforming growth factor, beta 3	0.031
RUNX1	runt-related transcription factor 1	0.030
GJA1	gap junction protein, alpha 1, 43kDa	0.030
STK38L	serine/threonine kinase 38 like	0.030
TWIST2	twist homolog 2 (Drosophila)	0.029
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.029	Fly
CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	0.029
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.028
PTEN	phosphatase and tensin homolog	0.028
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.028
BTRC	beta-transducin repeat containing	0.027
STK24	serine/threonine kinase 24	0.026	Fly
BAG1	BCL2-associated athanogene	0.026
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.025
PPL	periplakin	0.025
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.025
RIN1	Ras and Rab interactor 1	0.025
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.025
MKL2	MKL/myocardin-like 2	0.024
GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	0.024
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.024
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.024
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.023
TJP2	tight junction protein 2 (zona occludens 2)	0.023
STRN3	striatin, calmodulin binding protein 3	0.023
DDX47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47	0.023
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.023
CREBBP	CREB binding protein	0.023
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.022
KRT18	keratin 18	0.022
MYOG	myogenin (myogenic factor 4)	0.022
AR	androgen receptor	0.022
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.022
RFWD2	ring finger and WD repeat domain 2	0.022
HOXA7	homeobox A7	0.021
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.021
GLIS2	GLIS family zinc finger 2	0.021
LIMK1	LIM domain kinase 1	0.021
LIMD1	LIM domains containing 1	0.021
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.021
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.021
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.020
FRS2	fibroblast growth factor receptor substrate 2	0.020
AMOTL2	angiomotin like 2	0.020
WNT3A	wingless-type MMTV integration site family, member 3A	0.020
NCOR2	nuclear receptor corepressor 2	0.019
PDCD6	programmed cell death 6	0.019
VEGFA	vascular endothelial growth factor A	0.019
NRP1	neuropilin 1	0.019
PEBP4	phosphatidylethanolamine-binding protein 4	0.019
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.018
HDGF	hepatoma-derived growth factor	0.018
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.018
AMOTL1	angiomotin like 1	0.018
JUP	junction plakoglobin	0.018
NOG	noggin	0.018
ADRB2	adrenergic, beta-2-, receptor, surface	0.018
FGF2	fibroblast growth factor 2 (basic)	0.017
VHL	von Hippel-Lindau tumor suppressor	0.017
RALGDS	ral guanine nucleotide dissociation stimulator	0.017
EDAR	ectodysplasin A receptor	0.017
PEBP1	phosphatidylethanolamine binding protein 1	0.017
NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	0.017
SSX4	synovial sarcoma, X breakpoint 4	0.016
SP100	SP100 nuclear antigen	0.016
APC	adenomatous polyposis coli	0.016
MAP2K1	mitogen-activated protein kinase kinase 1	0.016
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.016
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.016
RXRB	retinoid X receptor, beta	0.016
LAT	linker for activation of T cells	0.016
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.016
NCOA6	nuclear receptor coactivator 6	0.016
CDH5	cadherin 5, type 2 (vascular endothelium)	0.016
P2RY1	purinergic receptor P2Y, G-protein coupled, 1	0.016
VMP1	vacuole membrane protein 1	0.016
PPARA	peroxisome proliferator-activated receptor alpha	0.016
TCP1	t-complex 1	0.016
PDCD10	programmed cell death 10	0.015
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.015
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.015
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.015
PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	0.015
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.015
KRT8	keratin 8	0.015
HMGA1	high mobility group AT-hook 1	0.015
CDK10	cyclin-dependent kinase 10	0.015
PTPN9	protein tyrosine phosphatase, non-receptor type 9	0.015
IGSF21	immunoglobin superfamily, member 21	0.015
NOTCH1	notch 1	0.015
FKBP4	FK506 binding protein 4, 59kDa	0.015
HARS	histidyl-tRNA synthetase	0.015
HOXA10	homeobox A10	0.015
FGF7	fibroblast growth factor 7	0.015
CCT7	chaperonin containing TCP1, subunit 7 (eta)	0.015
FOXO3	forkhead box O3	0.015
PLCG1	phospholipase C, gamma 1	0.014
LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	0.014
MYOD1	myogenic differentiation 1	0.014
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.014
ANKRD28	ankyrin repeat domain 28	0.014
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.014
SCRIB	scribbled homolog (Drosophila)	0.014
FAM40A	family with sequence similarity 40, member A	0.014
STK25	serine/threonine kinase 25	0.014	Fly
PRMT1	protein arginine methyltransferase 1	0.014
CHMP4B	chromatin modifying protein 4B	0.014
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.013
HDAC3	histone deacetylase 3	0.013
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.013
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	0.013
PLCE1	phospholipase C, epsilon 1	0.013
RHEB	Ras homolog enriched in brain	0.013
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.013
SMAD2	SMAD family member 2	0.013
NUAK1	NUAK family, SNF1-like kinase, 1	0.013
SAC3D1	SAC3 domain containing 1	0.013
POU2F1	POU class 2 homeobox 1	0.013
STX4	syntaxin 4	0.013
GJD3	gap junction protein, delta 3, 31.9kDa	0.013
NFIL3	nuclear factor, interleukin 3 regulated	0.013
GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	0.013
STIP1	stress-induced-phosphoprotein 1	0.013
SMAD7	SMAD family member 7	0.012
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.012
FGFR1	fibroblast growth factor receptor 1	0.012	Fly
ZNF576	zinc finger protein 576	0.012
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.012
AXIN2	axin 2	0.012
TWIST1	twist homolog 1 (Drosophila)	0.012
SOS1	son of sevenless homolog 1 (Drosophila)	0.012
FZD8	frizzled homolog 8 (Drosophila)	0.012
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.012
ATG14	ATG14 autophagy related 14 homolog (S. cerevisiae)	0.012
SREBF2	sterol regulatory element binding transcription factor 2	0.012
RAP1A	RAP1A, member of RAS oncogene family	0.012
PKP4	plakophilin 4	0.012
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.012
PPP6R2	protein phosphatase 6, regulatory subunit 2	0.012
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.011
PSEN1	presenilin 1	0.011
COL2A1	collagen, type II, alpha 1	0.011
AHR	aryl hydrocarbon receptor	0.011
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.011
FOXF2	forkhead box F2	0.011
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.011
CD2AP	CD2-associated protein	0.011
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.011
ITPA	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)	0.011
FHL1	four and a half LIM domains 1	0.011
FANCC	Fanconi anemia, complementation group C	0.011
C10orf47	chromosome 10 open reading frame 47	0.011
RRAS2	related RAS viral (r-ras) oncogene homolog 2	0.011
AXIN1	axin 1	0.011
EMD	emerin	0.011
FOXO1	forkhead box O1	0.011
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.011
FOXD3	forkhead box D3	0.011
HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor	0.011
NF2	neurofibromin 2 (merlin)	0.011
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.011
MYO6	myosin VI	0.011
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.011
VPS37C	vacuolar protein sorting 37 homolog C (S. cerevisiae)	0.011
FBXW11	F-box and WD repeat domain containing 11	0.011
STX12	syntaxin 12	0.011
HOXA4	homeobox A4	0.011
NOTCH3	notch 3	0.011
PPP4C	protein phosphatase 4, catalytic subunit	0.011
SHB	Src homology 2 domain containing adaptor protein B	0.011
KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.011	Fly
MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.011
LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2	0.010
ZFYVE26	zinc finger, FYVE domain containing 26	0.010
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.010
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.010
SETD8	SET domain containing (lysine methyltransferase) 8	0.010
SRI	sorcin	0.010
CARM1	coactivator-associated arginine methyltransferase 1	0.010
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.010
INADL	InaD-like (Drosophila)	0.010
HNF1A	HNF1 homeobox A	0.010
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.010
CRLF3	cytokine receptor-like factor 3	0.010
HOXB5	homeobox B5	0.010
FGF18	fibroblast growth factor 18	0.010
HOXA2	homeobox A2	0.010
SCFD1	sec1 family domain containing 1	0.010
GRIA2	glutamate receptor, ionotropic, AMPA 2	0.010
HOXA11	homeobox A11	0.010
TGFBR3	transforming growth factor, beta receptor III	0.010
PDGFA	platelet-derived growth factor alpha polypeptide	0.010
FER	fer (fps/fes related) tyrosine kinase	0.010
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.010
NDRG1	N-myc downstream regulated 1	0.010
DDX24	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24	0.010
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.010
NOSTRIN	nitric oxide synthase trafficker	0.010
MCM3AP	minichromosome maintenance complex component 3 associated protein	0.010