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Homo sapiens

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behavioral defense response

GO:0002209

A behavioral response seeking to protect an organism from an a perceived external threat to that organism.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "behavioral defense response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "behavioral defense response" (in gray)

Name	Description	Probability	Func Analog Organism
BCL2L1	BCL2-like 1	1.000
BAX	BCL2-associated X protein	0.727
MPDZ	multiple PDZ domain protein	0.672
HDAC4	histone deacetylase 4	0.600
CRHR1	corticotropin releasing hormone receptor 1	0.558
AMBRA1	autophagy/beclin-1 regulator 1	0.519
BAK1	BCL2-antagonist/killer 1	0.517
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.419
BECN1	beclin 1, autophagy related	0.377
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.355
DLG4	discs, large homolog 4 (Drosophila)	0.335
BAD	BCL2-associated agonist of cell death	0.313
RAI1	retinoic acid induced 1	0.280
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.250
RPL18A	ribosomal protein L18a	0.246
ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)	0.216
MYLK2	myosin light chain kinase 2	0.203
TP53BP2	tumor protein p53 binding protein, 2	0.201
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.174
BID	BH3 interacting domain death agonist	0.170
FKBP8	FK506 binding protein 8, 38kDa	0.145
BIK	BCL2-interacting killer (apoptosis-inducing)	0.135
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.119
PHLPP2	PH domain and leucine rich repeat protein phosphatase 2	0.105
KIFC2	kinesin family member C2	0.081
GLO1	glyoxalase I	0.076
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.071
VDAC2	voltage-dependent anion channel 2	0.070
HIPK2	homeodomain interacting protein kinase 2	0.066
DDX24	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24	0.064
UBXN2A	UBX domain protein 2A	0.060
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.060
LPL	lipoprotein lipase	0.059
WDR20	WD repeat domain 20	0.059
DUSP23	dual specificity phosphatase 23	0.058
CAMK2B	calcium/calmodulin-dependent protein kinase II beta	0.055
BBC3	BCL2 binding component 3	0.054
NIPSNAP1	nipsnap homolog 1 (C. elegans)	0.047
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.047
EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4	0.047
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.044
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.044
FHL1	four and a half LIM domains 1	0.042
ZNF784	zinc finger protein 784	0.042
MAPK8	mitogen-activated protein kinase 8	0.041
HDAC9	histone deacetylase 9	0.040
EP300	E1A binding protein p300	0.040
ASCC2	activating signal cointegrator 1 complex subunit 2	0.038
NDUFB3	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa	0.037
FSTL4	follistatin-like 4	0.036
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.035
PRDX1	peroxiredoxin 1	0.035
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.034
NAF1	nuclear assembly factor 1 homolog (S. cerevisiae)	0.034
RNF144B	ring finger protein 144B	0.033
CRMP1	collapsin response mediator protein 1	0.031
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.031
BCL2L2	BCL2-like 2	0.031
DAPK1	death-associated protein kinase 1	0.031
UVRAG	UV radiation resistance associated gene	0.030
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.030
ACTL6B	actin-like 6B	0.029
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.027
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.026
RAD23B	RAD23 homolog B (S. cerevisiae)	0.026
MLH1	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)	0.025
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.025
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.024
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.024
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.024
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.023
PLXNA3	plexin A3	0.023
AFF2	AF4/FMR2 family, member 2	0.023
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.022
CADM3	cell adhesion molecule 3	0.022
VDAC1	voltage-dependent anion channel 1	0.022	Mouse
DBN1	drebrin 1	0.022
METAP1	methionyl aminopeptidase 1	0.022
CA10	carbonic anhydrase X	0.021
GRIA4	glutamate receptor, ionotrophic, AMPA 4	0.021
SPNS1	spinster homolog 1 (Drosophila)	0.021
EEA1	early endosome antigen 1	0.021
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.020
SOD1	superoxide dismutase 1, soluble	0.020
GRIK1	glutamate receptor, ionotropic, kainate 1	0.020
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.019
EMX1	empty spiracles homeobox 1	0.019
HK1	hexokinase 1	0.019
WDR48	WD repeat domain 48	0.019
SSTR3	somatostatin receptor 3	0.019
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.019
NLGN1	neuroligin 1	0.019
GRIA2	glutamate receptor, ionotropic, AMPA 2	0.018
MAPK1	mitogen-activated protein kinase 1	0.018
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	0.018
RIBC2	RIB43A domain with coiled-coils 2	0.018
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.018
CCKBR	cholecystokinin B receptor	0.017	Rat
DLG2	discs, large homolog 2 (Drosophila)	0.017
ACAT2	acetyl-CoA acetyltransferase 2	0.017
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.017
ATG14	ATG14 autophagy related 14 homolog (S. cerevisiae)	0.017
CACNG3	calcium channel, voltage-dependent, gamma subunit 3	0.017
RNR2	l-rRNA	0.017
ZNF331	zinc finger protein 331	0.017
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.017
AES	amino-terminal enhancer of split	0.016
KCNJ9	potassium inwardly-rectifying channel, subfamily J, member 9	0.016
ASRGL1	asparaginase like 1	0.016
MAP2K7	mitogen-activated protein kinase kinase 7	0.016
INTS1	integrator complex subunit 1	0.016
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.016
GRM6	glutamate receptor, metabotropic 6	0.016
GSK3A	glycogen synthase kinase 3 alpha	0.016
PPHLN1	periphilin 1	0.016
ATF2	activating transcription factor 2	0.015
CRHR2	corticotropin releasing hormone receptor 2	0.015
ST8SIA3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.015
KCNK3	potassium channel, subfamily K, member 3	0.015
MAP2K1	mitogen-activated protein kinase kinase 1	0.015
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.015
SEZ6L	seizure related 6 homolog (mouse)-like	0.015
CENPB	centromere protein B, 80kDa	0.015
MRPL20	mitochondrial ribosomal protein L20	0.014
PRPS1	phosphoribosyl pyrophosphate synthetase 1	0.014
GFAP	glial fibrillary acidic protein	0.014
SIN3B	SIN3 homolog B, transcription regulator (yeast)	0.014
POU4F1	POU class 4 homeobox 1	0.014
HOXD12	homeobox D12	0.014
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.014
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.014
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.014
FDFT1	farnesyl-diphosphate farnesyltransferase 1	0.014
PRDX3	peroxiredoxin 3	0.014
BBS10	Bardet-Biedl syndrome 10	0.014
TCF4	transcription factor 4	0.014
UNC119	unc-119 homolog (C. elegans)	0.014
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.014
HPCAL4	hippocalcin like 4	0.014
LDHA	lactate dehydrogenase A	0.014
ZBTB4	zinc finger and BTB domain containing 4	0.014
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.014
CABP1	calcium binding protein 1	0.013
DCC	deleted in colorectal carcinoma	0.013
WASH1	WAS protein family homolog 1	0.013
DRD1	dopamine receptor D1	0.013	Mouse
RORB	RAR-related orphan receptor B	0.013
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	0.013
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.013
ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	0.013
VCP	valosin containing protein	0.013
SLITRK3	SLIT and NTRK-like family, member 3	0.013
FGF12	fibroblast growth factor 12	0.012
ZNF746	zinc finger protein 746	0.012
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.012
PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	0.012
CYCS	cytochrome c, somatic	0.012
GABRG3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.012
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.012
GRIK3	glutamate receptor, ionotropic, kainate 3	0.012
PGK1	phosphoglycerate kinase 1	0.012
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.012
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.012
FAM123A	family with sequence similarity 123A	0.012
RIMS1	regulating synaptic membrane exocytosis 1	0.012
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.012
FEZF2	FEZ family zinc finger 2	0.012
C14orf1	chromosome 14 open reading frame 1	0.012
BRP44	brain protein 44	0.011
SORCS3	sortilin-related VPS10 domain containing receptor 3	0.011
TRPM3	transient receptor potential cation channel, subfamily M, member 3	0.011
MDH1	malate dehydrogenase 1, NAD (soluble)	0.011
FOXG1	forkhead box G1	0.011
MAP3K12	mitogen-activated protein kinase kinase kinase 12	0.011
GRM7	glutamate receptor, metabotropic 7	0.011	Mouse
MAPK9	mitogen-activated protein kinase 9	0.011
SLC17A6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	0.011
C6orf203	chromosome 6 open reading frame 203	0.011
C10orf46	chromosome 10 open reading frame 46	0.011
NELL1	NEL-like 1 (chicken)	0.011
NSFL1C	NSFL1 (p97) cofactor (p47)	0.011
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.011
GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2	0.011
CACNG2	calcium channel, voltage-dependent, gamma subunit 2	0.011
FAM5B	family with sequence similarity 5, member B	0.011
CHN1	chimerin (chimaerin) 1	0.011
KCNJ3	potassium inwardly-rectifying channel, subfamily J, member 3	0.011
KIAA1045	KIAA1045	0.011
FABP5	fatty acid binding protein 5 (psoriasis-associated)	0.011
IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	0.011
EPHA5	EPH receptor A5	0.011
HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	0.011
GPR6	G protein-coupled receptor 6	0.011
PSEN2	presenilin 2 (Alzheimer disease 4)	0.011
PTPRR	protein tyrosine phosphatase, receptor type, R	0.011
SIX6	SIX homeobox 6	0.011
CDH8	cadherin 8, type 2	0.011
AKAP11	A kinase (PRKA) anchor protein 11	0.011
GRM5	glutamate receptor, metabotropic 5	0.011
COPG2	coatomer protein complex, subunit gamma 2	0.011
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.011
PAX6	paired box 6	0.011
KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.011
ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	0.011
FOXL1	forkhead box L1	0.011
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.011
ADAM11	ADAM metallopeptidase domain 11	0.011
GPR12	G protein-coupled receptor 12	0.011
RBMXL2	RNA binding motif protein, X-linked-like 2	0.011
SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	0.010
FH	fumarate hydratase	0.010
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.010
ACHE	acetylcholinesterase	0.010
NPY5R	neuropeptide Y receptor Y5	0.010
MYOD1	myogenic differentiation 1	0.010
ALDH9A1	aldehyde dehydrogenase 9 family, member A1	0.010
KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1	0.010
DOC2A	double C2-like domains, alpha	0.010
PIK3R4	phosphoinositide-3-kinase, regulatory subunit 4	0.010
MAPRE2	microtubule-associated protein, RP/EB family, member 2	0.010
SFN	stratifin	0.010
KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6	0.010
INA	internexin neuronal intermediate filament protein, alpha	0.010
RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	0.010
GABRD	gamma-aminobutyric acid (GABA) A receptor, delta	0.010
MEF2A	myocyte enhancer factor 2A	0.010
HTR1E	5-hydroxytryptamine (serotonin) receptor 1E	0.010
ATXN3	ataxin 3	0.010
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.010
KCNH1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.010
KCNV1	potassium channel, subfamily V, member 1	0.010
GRM1	glutamate receptor, metabotropic 1	0.010
AMOT	angiomotin	0.010
RALYL	RALY RNA binding protein-like	0.010
CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.010
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.010
DCAF7	DDB1 and CUL4 associated factor 7	0.010
SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)	0.010