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Homo sapiens

22 genes annotated in human

male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "male gamete generation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "male gamete generation" (in gray)

Name	Description	Probability	Func Analog Organism
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.839
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.802
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.216
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.104
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.099
CDK2	cyclin-dependent kinase 2	0.099
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.091	Fly
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.087
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.079
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.073
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.072
WASL	Wiskott-Aldrich syndrome-like	0.068	Fly
BRCA2	breast cancer 2, early onset	0.067	Mouse
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.063
NOTCH1	notch 1	0.060	Rat
PABPC1	poly(A) binding protein, cytoplasmic 1	0.051
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.050
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.050
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.050
BCL2	B-cell CLL/lymphoma 2	0.048
RIPK2	receptor-interacting serine-threonine kinase 2	0.043
CCNA2	cyclin A2	0.041
BRCA1	breast cancer 1, early onset	0.041
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.040
XIAP	X-linked inhibitor of apoptosis	0.040
BIRC2	baculoviral IAP repeat containing 2	0.038
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.038	Fly
VDAC1	voltage-dependent anion channel 1	0.038	Fly
SIRT1	sirtuin 1	0.037	Mouse
KIF23	kinesin family member 23	0.035
CSNK2B	casein kinase 2, beta polypeptide	0.035
SKP2	S-phase kinase-associated protein 2 (p45)	0.035
PBK	PDZ binding kinase	0.034
H2AFX	H2A histone family, member X	0.032	Mouse
EIF4A2	eukaryotic translation initiation factor 4A2	0.032
NOTCH3	notch 3	0.032
SOS1	son of sevenless homolog 1 (Drosophila)	0.030
UBQLN1	ubiquilin 1	0.030
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.030
MED28	mediator complex subunit 28	0.029
PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	0.029
BAK1	BCL2-antagonist/killer 1	0.029
IRS1	insulin receptor substrate 1	0.028	Fly
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.028	Fly
GSK3B	glycogen synthase kinase 3 beta	0.027	Fly
TSKS	testis-specific serine kinase substrate	0.027
YAP1	Yes-associated protein 1	0.026
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.026
SCHIP1	schwannomin interacting protein 1	0.025
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.025
LAT	linker for activation of T cells	0.025
BCL9	B-cell CLL/lymphoma 9	0.024
SKP1	S-phase kinase-associated protein 1	0.024
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.023
PSEN2	presenilin 2 (Alzheimer disease 4)	0.023
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.023
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.023
CUL4B	cullin 4B	0.023
SYNE1	spectrin repeat containing, nuclear envelope 1	0.023
DYNLL1	dynein, light chain, LC8-type 1	0.022	Fly
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.022
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.022
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.022
EPS15	epidermal growth factor receptor pathway substrate 15	0.021
EIF3L	eukaryotic translation initiation factor 3, subunit L	0.021
SMAD3	SMAD family member 3	0.021
HDAC2	histone deacetylase 2	0.021
UHRF1	ubiquitin-like with PHD and ring finger domains 1	0.021
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.021
DAXX	death-domain associated protein	0.020
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.020
GRB10	growth factor receptor-bound protein 10	0.020
COX17	COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)	0.020
PLK1	polo-like kinase 1	0.020	Fly
HDAC1	histone deacetylase 1	0.020
BCL2L1	BCL2-like 1	0.020	Mouse
EED	embryonic ectoderm development	0.019
EGFR	epidermal growth factor receptor	0.019
ARID4B	AT rich interactive domain 4B (RBP1-like)	0.019	Mouse
PHC2	polyhomeotic homolog 2 (Drosophila)	0.019	Mouse
CAPRIN1	cell cycle associated protein 1	0.019
PTGES3	prostaglandin E synthase 3 (cytosolic)	0.019
APC	adenomatous polyposis coli	0.019
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.019
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.019
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.019	Rat
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.018
PML	promyelocytic leukemia	0.018
UBE3A	ubiquitin protein ligase E3A	0.018
FANCD2	Fanconi anemia, complementation group D2	0.018
MPDZ	multiple PDZ domain protein	0.018
STIL	SCL/TAL1 interrupting locus	0.018
UBE2K	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)	0.018
ATXN1	ataxin 1	0.018
SFN	stratifin	0.018
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.018	Fly
TOB1	transducer of ERBB2, 1	0.018
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.017
HSPA8	heat shock 70kDa protein 8	0.017
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.017	Fly
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.017
BIRC6	baculoviral IAP repeat containing 6	0.017
RAD23A	RAD23 homolog A (S. cerevisiae)	0.017
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.017
SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.017
UQCRC2	ubiquinol-cytochrome c reductase core protein II	0.017
SRSF10	serine/arginine-rich splicing factor 10	0.017
RORA	RAR-related orphan receptor A	0.016
NXF1	nuclear RNA export factor 1	0.016
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.016
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.016	Mouse
PDPK1	3-phosphoinositide dependent protein kinase-1	0.016
XPO1	exportin 1 (CRM1 homolog, yeast)	0.016
SNX9	sorting nexin 9	0.016
CREBBP	CREB binding protein	0.016	Worm
CDK1	cyclin-dependent kinase 1	0.016	Fly
MTA1	metastasis associated 1	0.015
RAD21	RAD21 homolog (S. pombe)	0.015
CDT1	chromatin licensing and DNA replication factor 1	0.015
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.015
TXN	thioredoxin	0.015
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.015
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.015
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.015
HDAC4	histone deacetylase 4	0.015
ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.015
SYNE2	spectrin repeat containing, nuclear envelope 2	0.015
RSBN1	round spermatid basic protein 1	0.015
ESR1	estrogen receptor 1	0.015
BCAR1	breast cancer anti-estrogen resistance 1	0.015
RGS2	regulator of G-protein signaling 2, 24kDa	0.014	Mouse
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.014
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.014	Fly
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.014
EZH2	enhancer of zeste homolog 2 (Drosophila)	0.014
MED25	mediator complex subunit 25	0.014
SOS2	son of sevenless homolog 2 (Drosophila)	0.014
TRIP6	thyroid hormone receptor interactor 6	0.014
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.013
CLASP2	cytoplasmic linker associated protein 2	0.013
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.013	Fly
CLCN3	chloride channel 3	0.013
CCNB1	cyclin B1	0.013	Rat
DICER1	dicer 1, ribonuclease type III	0.013
GRB7	growth factor receptor-bound protein 7	0.013
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.013
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.013
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.013
TUBGCP3	tubulin, gamma complex associated protein 3	0.013
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.012
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.012
SAP30BP	SAP30 binding protein	0.012
CKS2	CDC28 protein kinase regulatory subunit 2	0.012
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.012
SYK	spleen tyrosine kinase	0.012
PRDX1	peroxiredoxin 1	0.012
HIST2H3C	histone cluster 2, H3c	0.012
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.012
TLK1	tousled-like kinase 1	0.012
TAL1	T-cell acute lymphocytic leukemia 1	0.012
BAX	BCL2-associated X protein	0.012	Mouse
JAG1	jagged 1	0.012	Human
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.012
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.012
FGFR1	fibroblast growth factor receptor 1	0.012
REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)	0.012
RXRA	retinoid X receptor, alpha	0.012
MED21	mediator complex subunit 21	0.012
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.012
BTRC	beta-transducin repeat containing	0.012
VCP	valosin containing protein	0.012
CCNE1	cyclin E1	0.011
DNM1	dynamin 1	0.011	Fly
ATP13A2	ATPase type 13A2	0.011
MAP2K1	mitogen-activated protein kinase kinase 1	0.011
SF3B4	splicing factor 3b, subunit 4, 49kDa	0.011
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.011
CCNB2	cyclin B2	0.011
TEX11	testis expressed 11	0.011
RBBP4	retinoblastoma binding protein 4	0.011
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.011	Mouse
NLRC4	NLR family, CARD domain containing 4	0.011
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.011
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.011
CNOT8	CCR4-NOT transcription complex, subunit 8	0.011
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.011	Mouse Rat
C5orf41	chromosome 5 open reading frame 41	0.011
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.011
GAB1	GRB2-associated binding protein 1	0.011
MRPL18	mitochondrial ribosomal protein L18	0.011
SP1	Sp1 transcription factor	0.011
UBXN7	UBX domain protein 7	0.011
CLOCK	clock homolog (mouse)	0.011	Mouse
EIF4A1	eukaryotic translation initiation factor 4A1	0.011
SRSF1	serine/arginine-rich splicing factor 1	0.011
HCFC1	host cell factor C1 (VP16-accessory protein)	0.011
TMPO	thymopoietin	0.011
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.011
METTL1	methyltransferase like 1	0.011
UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.011
TAOK1	TAO kinase 1	0.010
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.010
EXOC7	exocyst complex component 7	0.010
MAPK1	mitogen-activated protein kinase 1	0.010
EP300	E1A binding protein p300	0.010	Worm
ARID4A	AT rich interactive domain 4A (RBP1-like)	0.010	Mouse
DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.010	Mouse
PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	0.010
HSF1	heat shock transcription factor 1	0.010	Mouse
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.010
SON	SON DNA binding protein	0.010
ZNF746	zinc finger protein 746	0.010
VPS29	vacuolar protein sorting 29 homolog (S. cerevisiae)	0.010
CNOT6	CCR4-NOT transcription complex, subunit 6	0.010
MAPK6	mitogen-activated protein kinase 6	0.010
ATXN3	ataxin 3	0.010
WEE1	WEE1 homolog (S. pombe)	0.010
FRA10AC1	fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	0.010
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.010
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.010
PRDX3	peroxiredoxin 3	0.010