IMP

Process View

Homo sapiens

28 genes annotated in human

regulation of glucose metabolic process

Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of glucose metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of glucose metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
INSR	insulin receptor	0.999
C1QA	complement component 1, q subcomponent, A chain	0.966	Human
NCOA1	nuclear receptor coactivator 1	0.946
AR	androgen receptor	0.873
IRS2	insulin receptor substrate 2	0.859
PGK1	phosphoglycerate kinase 1	0.856
GRB10	growth factor receptor-bound protein 10	0.856	Rat
IRS1	insulin receptor substrate 1	0.819
CREBBP	CREB binding protein	0.736
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.725
ESR1	estrogen receptor 1	0.704
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.668
IGF1R	insulin-like growth factor 1 receptor	0.659	Human
TADA3	transcriptional adaptor 3	0.633
GHR	growth hormone receptor	0.589
RXRA	retinoid X receptor, alpha	0.538
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.517
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.438	Human
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.395
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.353
ZNF746	zinc finger protein 746	0.331
NOXA1	NADPH oxidase activator 1	0.329
HNF4A	hepatocyte nuclear factor 4, alpha	0.276	Rat
ALDOA	aldolase A, fructose-bisphosphate	0.247
TPI1	triosephosphate isomerase 1	0.243
RARA	retinoic acid receptor, alpha	0.203	Human
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.198
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.196
SQSTM1	sequestosome 1	0.190
ENO1	enolase 1, (alpha)	0.166
LDHA	lactate dehydrogenase A	0.159
FHL2	four and a half LIM domains 2	0.152
EP300	E1A binding protein p300	0.146
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.137
SH2B1	SH2B adaptor protein 1	0.136
C1QC	complement component 1, q subcomponent, C chain	0.132	Human
GSK3B	glycogen synthase kinase 3 beta	0.123
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.111
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.108
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.098
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.096	Human
USP22	ubiquitin specific peptidase 22	0.096
ACACA	acetyl-CoA carboxylase alpha	0.091
PDPK1	3-phosphoinositide dependent protein kinase-1	0.088
C1QB	complement component 1, q subcomponent, B chain	0.086	Human
KAT2B	K(lysine) acetyltransferase 2B	0.085	Mouse
LZTS2	leucine zipper, putative tumor suppressor 2	0.084
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.083	Yeast
NCOA6	nuclear receptor coactivator 6	0.082
STAT5B	signal transducer and activator of transcription 5B	0.079
RAB6A	RAB6A, member RAS oncogene family	0.079
ITGB1BP3	integrin beta 1 binding protein 3	0.078
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.066
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.065
SIRT1	sirtuin 1	0.065	Mouse
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.060
TADA2A	transcriptional adaptor 2A	0.059
HR	hairless homolog (mouse)	0.059
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.058
FOXO3	forkhead box O3	0.056
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.052
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.052
TRRAP	transformation/transcription domain-associated protein	0.051
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.051
PRKCZ	protein kinase C, zeta	0.050	Human
FUNDC2	FUN14 domain containing 2	0.049
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.047
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.045
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.045
SORBS3	sorbin and SH3 domain containing 3	0.043
GCK	glucokinase (hexokinase 4)	0.041
PRKCA	protein kinase C, alpha	0.038
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.038	Human
TP53	tumor protein p53	0.037
NCOA3	nuclear receptor coactivator 3	0.036
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.035
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.035
PKM2	pyruvate kinase, muscle	0.035
MED25	mediator complex subunit 25	0.034
PROX1	prospero homeobox 1	0.034
OSBP	oxysterol binding protein	0.034
GPI	glucose-6-phosphate isomerase	0.033
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.033
CCDC101	coiled-coil domain containing 101	0.033
HIPK2	homeodomain interacting protein kinase 2	0.033
CREB1	cAMP responsive element binding protein 1	0.033
SMAD3	SMAD family member 3	0.031
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.030	Yeast
PECAM1	platelet/endothelial cell adhesion molecule	0.030
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.030
ULK1	unc-51-like kinase 1 (C. elegans)	0.030
GABARAPL1	GABA(A) receptor-associated protein like 1	0.030
APC	adenomatous polyposis coli	0.030
NCF1	neutrophil cytosolic factor 1	0.029
C5orf41	chromosome 5 open reading frame 41	0.028
PINK1	PTEN induced putative kinase 1	0.027
PRKCB	protein kinase C, beta	0.027
CDCP1	CUB domain containing protein 1	0.027
ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	0.026
ARF4	ADP-ribosylation factor 4	0.025
BCL2	B-cell CLL/lymphoma 2	0.025
WRN	Werner syndrome, RecQ helicase-like	0.025
MARCO	macrophage receptor with collagenous structure	0.025
DCN	decorin	0.024
RUNX1	runt-related transcription factor 1	0.024
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.023
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.023	Rat
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.023
C1R	complement component 1, r subcomponent	0.023
BAG3	BCL2-associated athanogene 3	0.023
FHOD3	formin homology 2 domain containing 3	0.022
ATXN7	ataxin 7	0.022
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.022
CCL14	chemokine (C-C motif) ligand 14	0.022
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.021
BAD	BCL2-associated agonist of cell death	0.021
ADAM12	ADAM metallopeptidase domain 12	0.021
GOLGA8B	golgin A8 family, member B	0.021
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.021
TF	transferrin	0.021
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.021
FAF1	Fas (TNFRSF6) associated factor 1	0.020
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.020	Yeast
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.020
JAK2	Janus kinase 2	0.020
BCAR1	breast cancer anti-estrogen resistance 1	0.020
IGF1	insulin-like growth factor 1 (somatomedin C)	0.020
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.019	Rat
CCND3	cyclin D3	0.019
ZER1	zer-1 homolog (C. elegans)	0.019
RPTOR	regulatory associated protein of MTOR, complex 1	0.019
ING5	inhibitor of growth family, member 5	0.019
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.019
GCKR	glucokinase (hexokinase 4) regulator	0.019
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.019
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.019
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.018
EGFR	epidermal growth factor receptor	0.018
RAD23A	RAD23 homolog A (S. cerevisiae)	0.018
ACTB	actin, beta	0.018
BHLHE40	basic helix-loop-helix family, member e40	0.018
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.017
SESN2	sestrin 2	0.017	Mouse
CXXC1	CXXC finger protein 1	0.017
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.017
ENO2	enolase 2 (gamma, neuronal)	0.017
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.017
ONECUT1	one cut homeobox 1	0.016
CCND1	cyclin D1	0.016
PPARA	peroxisome proliferator-activated receptor alpha	0.016	Mouse
ARID4B	AT rich interactive domain 4B (RBP1-like)	0.016
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.016
GRB14	growth factor receptor-bound protein 14	0.016
CD2	CD2 molecule	0.016
SH2D1A	SH2 domain containing 1A	0.016
PDCD2	programmed cell death 2	0.016
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.016
GLTPD1	glycolipid transfer protein domain containing 1	0.016
SREBF2	sterol regulatory element binding transcription factor 2	0.016
ZNF71	zinc finger protein 71	0.016
CCNL2	cyclin L2	0.015
IER2	immediate early response 2	0.015
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.015
CLK3	CDC-like kinase 3	0.015
NCOR1	nuclear receptor corepressor 1	0.015
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.015
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.015
PICK1	protein interacting with PRKCA 1	0.015
CREBZF	CREB/ATF bZIP transcription factor	0.015
SMAD7	SMAD family member 7	0.015
C1S	complement component 1, s subcomponent	0.015
ASXL1	additional sex combs like 1 (Drosophila)	0.015
LUC7L	LUC7-like (S. cerevisiae)	0.015
IGF2R	insulin-like growth factor 2 receptor	0.014
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.014
NUMB	numb homolog (Drosophila)	0.014
PSEN1	presenilin 1	0.014
TNIK	TRAF2 and NCK interacting kinase	0.014
CXCL12	chemokine (C-X-C motif) ligand 12	0.014
DCAF7	DDB1 and CUL4 associated factor 7	0.014
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.013
IGFBP3	insulin-like growth factor binding protein 3	0.013	Mouse
ERO1L	ERO1-like (S. cerevisiae)	0.013
SOCS3	suppressor of cytokine signaling 3	0.013
COL1A1	collagen, type I, alpha 1	0.013
RNF103	ring finger protein 103	0.013
SH3RF1	SH3 domain containing ring finger 1	0.013
FN1	fibronectin 1	0.013
MBD6	methyl-CpG binding domain protein 6	0.013
BTRC	beta-transducin repeat containing	0.013
AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	0.013
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.013
ARIH2	ariadne homolog 2 (Drosophila)	0.012
CYBA	cytochrome b-245, alpha polypeptide	0.012
PCNA	proliferating cell nuclear antigen	0.012
DEPTOR	DEP domain containing MTOR-interacting protein	0.012
DUSP5	dual specificity phosphatase 5	0.012
EPAS1	endothelial PAS domain protein 1	0.012
NCOR2	nuclear receptor corepressor 2	0.012
CLTC	clathrin, heavy chain (Hc)	0.012
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.012
IL32	interleukin 32	0.012
ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	0.011
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.011
FNBP1L	formin binding protein 1-like	0.011
GLRX3	glutaredoxin 3	0.011
PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.011	Yeast
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.011
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.011
SETD1A	SET domain containing 1A	0.011
BRAP	BRCA1 associated protein	0.011
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.011
PILRB	paired immunoglobin-like type 2 receptor beta	0.011
INPPL1	inositol polyphosphate phosphatase-like 1	0.011
CDK6	cyclin-dependent kinase 6	0.011
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.011
GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.011
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.011
ENPP5	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	0.011
RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	0.010
S100A2	S100 calcium binding protein A2	0.010
APOA1	apolipoprotein A-I	0.010
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.010
VSIG4	V-set and immunoglobulin domain containing 4	0.010
ITGA1	integrin, alpha 1	0.010
SH2D2A	SH2 domain containing 2A	0.010