IMP

Process View

Homo sapiens

33 genes annotated in human

Multi-species View

single organism carbohydrate catabolic process

GO:0044724

The chemical reactions and pathways resulting in the breakdown of carbohydrates, occurring within a single organism.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "single organism carbohydrate catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "single organism carbohydrate catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.998	Fly
ENO1	enolase 1, (alpha)	0.992	Mouse
ALDOA	aldolase A, fructose-bisphosphate	0.987
PGK1	phosphoglycerate kinase 1	0.984	Mouse
GPI	glucose-6-phosphate isomerase	0.978	Mouse
PKM2	pyruvate kinase, muscle	0.973
TPI1	triosephosphate isomerase 1	0.970	Fly
LDHA	lactate dehydrogenase A	0.896
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.876
NCOR2	nuclear receptor corepressor 2	0.872	Human
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.869	Rat
CTSA	cathepsin A	0.797
PGAM1	phosphoglycerate mutase 1 (brain)	0.622
GRN	granulin	0.604
TKT	transketolase	0.597
GLB1	galactosidase, beta 1	0.576	Rat
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.536
HK1	hexokinase 1	0.507	Yeast
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.502
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.457
ENO2	enolase 2 (gamma, neuronal)	0.370	Rat
PPARA	peroxisome proliferator-activated receptor alpha	0.352
HNF4A	hepatocyte nuclear factor 4, alpha	0.294
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.242
PFKL	phosphofructokinase, liver	0.237
RXRA	retinoid X receptor, alpha	0.233
IGF2R	insulin-like growth factor 2 receptor	0.217
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.200
IGF1R	insulin-like growth factor 1 receptor	0.180	Human
PPARG	peroxisome proliferator-activated receptor gamma	0.179	Human
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.177
NCOR1	nuclear receptor corepressor 1	0.173
NCOA1	nuclear receptor coactivator 1	0.148
GRB10	growth factor receptor-bound protein 10	0.144
ITGB1BP3	integrin beta 1 binding protein 3	0.143
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.132
EGFR	epidermal growth factor receptor	0.122
VEGFA	vascular endothelial growth factor A	0.100
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.099
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.096
IRS1	insulin receptor substrate 1	0.087
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.084
GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.079	Mouse
TALDO1	transaldolase 1	0.071
AGXT2	alanine--glyoxylate aminotransferase 2	0.070
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.069
VDAC1	voltage-dependent anion channel 1	0.068
ESR1	estrogen receptor 1	0.065
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.064
GYS1	glycogen synthase 1 (muscle)	0.064
BCL6	B-cell CLL/lymphoma 6	0.063
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.063
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.062	Human
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.061
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.060
BBS1	Bardet-Biedl syndrome 1	0.059
RARA	retinoic acid receptor, alpha	0.056
GCKR	glucokinase (hexokinase 4) regulator	0.050
NEU1	sialidase 1 (lysosomal sialidase)	0.050
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.048
GHR	growth hormone receptor	0.047
ESRRG	estrogen-related receptor gamma	0.043
FAF1	Fas (TNFRSF6) associated factor 1	0.042
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.040
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.040
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.039
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.039
BCL3	B-cell CLL/lymphoma 3	0.039
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.038
SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	0.037
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.037
PFKP	phosphofructokinase, platelet	0.035	Human
SMAD9	SMAD family member 9	0.034
JAK2	Janus kinase 2	0.034
PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.034	Rat
PDPK1	3-phosphoinositide dependent protein kinase-1	0.033
CAPRIN2	caprin family member 2	0.033
MEF2A	myocyte enhancer factor 2A	0.033
BHLHE40	basic helix-loop-helix family, member e40	0.033
MAP4	microtubule-associated protein 4	0.032
FBP2	fructose-1,6-bisphosphatase 2	0.032	Human
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.032
TUBA4A	tubulin, alpha 4a	0.032
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.032
CTSB	cathepsin B	0.031
ALDOC	aldolase C, fructose-bisphosphate	0.030	Human Fly
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.030
LRRK2	leucine-rich repeat kinase 2	0.029
PGM1	phosphoglucomutase 1	0.029
CALR	calreticulin	0.029
PGD	phosphogluconate dehydrogenase	0.028
PRKCSH	protein kinase C substrate 80K-H	0.027
NDRG1	N-myc downstream regulated 1	0.027
RNPEP	arginyl aminopeptidase (aminopeptidase B)	0.027
PGR	progesterone receptor	0.027
GSK3B	glycogen synthase kinase 3 beta	0.026
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.026
IRS2	insulin receptor substrate 2	0.026
PTN	pleiotrophin	0.025
CAPNS1	calpain, small subunit 1	0.025
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.025
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.025
HDAC1	histone deacetylase 1	0.024
MBL2	mannose-binding lectin (protein C) 2, soluble	0.024
CORO1B	coronin, actin binding protein, 1B	0.024
HDAC5	histone deacetylase 5	0.023
PGAM2	phosphoglycerate mutase 2 (muscle)	0.023
EGLN3	egl nine homolog 3 (C. elegans)	0.022
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.022
GAPDHS	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.022	Fly
GNS	glucosamine (N-acetyl)-6-sulfatase	0.022
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.022
BCKDK	branched chain ketoacid dehydrogenase kinase	0.021
EPOR	erythropoietin receptor	0.021
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.020
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.020
MIF4GD	MIF4G domain containing	0.020
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.020
ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.019
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.019
IL8	interleukin 8	0.019
HR	hairless homolog (mouse)	0.019
G6PD	glucose-6-phosphate dehydrogenase	0.019
C16orf45	chromosome 16 open reading frame 45	0.019
PFKM	phosphofructokinase, muscle	0.018
APOC2	apolipoprotein C-II	0.018
SS18	synovial sarcoma translocation, chromosome 18	0.018
ENO3	enolase 3 (beta, muscle)	0.018	Yeast
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.018
HDAC4	histone deacetylase 4	0.018	Mouse
SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	0.018
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.017
ARID2	AT rich interactive domain 2 (ARID, RFX-like)	0.017
PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A	0.017
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.017
SND1	staphylococcal nuclease and tudor domain containing 1	0.017
ACACA	acetyl-CoA carboxylase alpha	0.017
INSR	insulin receptor	0.017
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.016	Human
TF	transferrin	0.016
MPV17	MpV17 mitochondrial inner membrane protein	0.016
OSGEPL1	O-sialoglycoprotein endopeptidase-like 1	0.016
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.016
HCFC1	host cell factor C1 (VP16-accessory protein)	0.016
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.016
MARCO	macrophage receptor with collagenous structure	0.016
LOC729020	rcRPE	0.016
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.016
PPT1	palmitoyl-protein thioesterase 1	0.015
HDAC3	histone deacetylase 3	0.015
BBS2	Bardet-Biedl syndrome 2	0.015
DDB1	damage-specific DNA binding protein 1, 127kDa	0.015
SAP30	Sin3A-associated protein, 30kDa	0.015
HEXB	hexosaminidase B (beta polypeptide)	0.015	Mouse
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.015
KDELR1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	0.015
CDHR2	cadherin-related family member 2	0.015
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.015
APP	amyloid beta (A4) precursor protein	0.014
GK	glycerol kinase	0.014
BAD	BCL2-associated agonist of cell death	0.014
IDH2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	0.014
CHD4	chromodomain helicase DNA binding protein 4	0.014
DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase	0.014
TXNIP	thioredoxin interacting protein	0.014
AQP7	aquaporin 7	0.014
FUCA1	fucosidase, alpha-L- 1, tissue	0.014
VIL1	villin 1	0.014
MLX	MAX-like protein X	0.014
SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	0.013
S100A1	S100 calcium binding protein A1	0.013
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.013	Yeast
BBS4	Bardet-Biedl syndrome 4	0.013
TUBB	tubulin, beta	0.013
PID1	phosphotyrosine interaction domain containing 1	0.013
NONO	non-POU domain containing, octamer-binding	0.013
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.013	Human
ERP29	endoplasmic reticulum protein 29	0.013
PCNA	proliferating cell nuclear antigen	0.013
APOE	apolipoprotein E	0.013
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.013
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.013
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.013
MAN2B1	mannosidase, alpha, class 2B, member 1	0.013
HEXA	hexosaminidase A (alpha polypeptide)	0.013
CDHR5	cadherin-related family member 5	0.013
C9orf16	chromosome 9 open reading frame 16	0.013
ADM	adrenomedullin	0.013
HP	haptoglobin	0.012
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.012
ZBTB7B	zinc finger and BTB domain containing 7B	0.012
PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	0.012
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.012
C7orf68	chromosome 7 open reading frame 68	0.012
SP1	Sp1 transcription factor	0.012
M6PR	mannose-6-phosphate receptor (cation dependent)	0.012
CD300C	CD300c molecule	0.012
RXRG	retinoid X receptor, gamma	0.012
MBD1	methyl-CpG binding domain protein 1	0.012
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.012
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.012
SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	0.012
MORC4	MORC family CW-type zinc finger 4	0.012
CTSL1	cathepsin L1	0.012
TPP1	tripeptidyl peptidase I	0.012
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.012
MED25	mediator complex subunit 25	0.012
CD33	CD33 molecule	0.012
GLYAT	glycine-N-acyltransferase	0.012
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.012
NIPSNAP1	nipsnap homolog 1 (C. elegans)	0.012
BSG	basigin (Ok blood group)	0.012
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.012
LMTK2	lemur tyrosine kinase 2	0.011
TM9SF4	transmembrane 9 superfamily protein member 4	0.011
IGFBP3	insulin-like growth factor binding protein 3	0.011
DCN	decorin	0.011
MANBA	mannosidase, beta A, lysosomal	0.011
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.011
FABP1	fatty acid binding protein 1, liver	0.011
CHD9	chromodomain helicase DNA binding protein 9	0.011
SOD2	superoxide dismutase 2, mitochondrial	0.011
CFL1	cofilin 1 (non-muscle)	0.011
PLD3	phospholipase D family, member 3	0.011
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.011
PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	0.011	Human
PPP1R10	protein phosphatase 1, regulatory (inhibitor) subunit 10	0.011
CD4	CD4 molecule	0.011
ACTN3	actinin, alpha 3	0.011
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.011
GLA	galactosidase, alpha	0.011
DDX41	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	0.011
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.011
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.011	Human
APOB	apolipoprotein B (including Ag(x) antigen)	0.011
NFIL3	nuclear factor, interleukin 3 regulated	0.011
UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	0.011
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.011
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.011
ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	0.011
RBM11	RNA binding motif protein 11	0.011
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.011
CAV1	caveolin 1, caveolae protein, 22kDa	0.010
BBS7	Bardet-Biedl syndrome 7	0.010
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.010
CKMT2	creatine kinase, mitochondrial 2 (sarcomeric)	0.010
HAAO	3-hydroxyanthranilate 3,4-dioxygenase	0.010
CXCL3	chemokine (C-X-C motif) ligand 3	0.010
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.010
PROX1	prospero homeobox 1	0.010
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.010
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.010
SGK2	serum/glucocorticoid regulated kinase 2	0.010
ANGPTL4	angiopoietin-like 4	0.010
ALDOB	aldolase B, fructose-bisphosphate	0.010
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.010
CLCN1	chloride channel 1, skeletal muscle	0.010
MUC20	mucin 20, cell surface associated	0.010
AGXT	alanine-glyoxylate aminotransferase	0.010
APOC3	apolipoprotein C-III	0.010
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.010
C3orf1	chromosome 3 open reading frame 1	0.010
LDHC	lactate dehydrogenase C	0.010