IMP

Process View

Mus musculus

1 genes annotated in mouse

fc receptor mediated inhibitory signaling pathway

A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "fc receptor mediated inhibitory signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "fc receptor mediated inhibitory signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Ikzf1	IKAROS family zinc finger 1	0.891
Ptprc	protein tyrosine phosphatase, receptor type, C	0.640
Cd19	CD19 antigen	0.556
Was	Wiskott-Aldrich syndrome homolog (human)	0.465
Inpp5d	inositol polyphosphate-5-phosphatase D	0.312
Cd22	CD22 antigen	0.292
Fyn	Fyn proto-oncogene	0.245	Mouse
Plcg2	phospholipase C, gamma 2	0.235
Lck	lymphocyte protein tyrosine kinase	0.223	Mouse
Hcls1	hematopoietic cell specific Lyn substrate 1	0.200
Il2rb	interleukin 2 receptor, beta chain	0.200
Cd247	CD247 antigen	0.178
Ptk2	PTK2 protein tyrosine kinase 2	0.159
Cbl	Casitas B-lineage lymphoma	0.147
Il2rg	interleukin 2 receptor, gamma chain	0.142
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.128
Fyb	FYN binding protein	0.121
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.109
Clnk	cytokine-dependent hematopoietic cell linker	0.109
Cd40	CD40 antigen	0.107
Ptpre	protein tyrosine phosphatase, receptor type, E	0.107
Pou2af1	POU domain, class 2, associating factor 1	0.091
Ccr6	chemokine (C-C motif) receptor 6	0.089
Dok2	docking protein 2	0.087
Blnk	B-cell linker	0.081
Itgax	integrin alpha X	0.076
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.073
Lyl1	lymphoblastomic leukemia 1	0.071
Lat	linker for activation of T cells	0.062
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.061
Rasa1	RAS p21 protein activator 1	0.061
Laptm5	lysosomal-associated protein transmembrane 5	0.060
Prkce	protein kinase C, epsilon	0.059
Dok1	docking protein 1	0.058
Itgb2	integrin beta 2	0.057
Foxn1	forkhead box N1	0.056
Cd180	CD180 antigen	0.055
Tnf	tumor necrosis factor	0.053
Ncr1	natural cytotoxicity triggering receptor 1	0.051
Cybb	cytochrome b-245, beta polypeptide	0.049
AF251705	cDNA sequence AF251705	0.047
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.046
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.045
Cd8a	CD8 antigen, alpha chain	0.041
Fas	Fas (TNF receptor superfamily member 6)	0.041
Wipf1	WAS/WASL interacting protein family, member 1	0.041
Cd4	CD4 antigen	0.040
Sykb	spleen tyrosine kinase	0.039
Igh	immunoglobulin heavy chain complex	0.038
Hck	hemopoietic cell kinase	0.037	Mouse
Cd7	CD7 antigen	0.036
Cd5	CD5 antigen	0.036
Sash3	SAM and SH3 domain containing 3	0.035
Cd37	CD37 antigen	0.035
Csf1	colony stimulating factor 1 (macrophage)	0.035
BC013712	cDNA sequence BC013712	0.035
Bcar1	breast cancer anti-estrogen resistance 1	0.034
Zap70	zeta-chain (TCR) associated protein kinase	0.034
Cd72	CD72 antigen	0.032
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.032
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.032
Icos	inducible T-cell co-stimulator	0.032
Cxcr3	chemokine (C-X-C motif) receptor 3	0.031
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.030
Rac2	RAS-related C3 botulinum substrate 2	0.030
Cd28	CD28 antigen	0.030
Cd8b1	CD8 antigen, beta chain 1	0.030
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.029
Myo1f	myosin IF	0.029
Nfam1	Nfat activating molecule with ITAM motif 1	0.029
Pxn	paxillin	0.028
Itgal	integrin alpha L	0.028
Cdcp1	CUB domain containing protein 1	0.028
Csf1r	colony stimulating factor 1 receptor	0.028
Rgs14	regulator of G-protein signaling 14	0.027
Lcp2	lymphocyte cytosolic protein 2	0.027
Ccl4	chemokine (C-C motif) ligand 4	0.027
Myo1g	myosin IG	0.026
Fcgr1	Fc receptor, IgG, high affinity I	0.026
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.026
Ctsw	cathepsin W	0.025
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.025
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.025
Ifng	interferon gamma	0.025
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.024
Mcoln2	mucolipin 2	0.024
Cd96	CD96 antigen	0.024
Fpr1	formyl peptide receptor 1	0.024
Rasal3	RAS protein activator like 3	0.024
Ciita	class II transactivator	0.024
Ptprcap	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein	0.023
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.023
Fam83f	family with sequence similarity 83, member F	0.023
Xcr1	chemokine (C motif) receptor 1	0.023
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.023
Il4	interleukin 4	0.023
Gpr97	G protein-coupled receptor 97	0.023
Ngp	neutrophilic granule protein	0.022
Hcst	hematopoietic cell signal transducer	0.022
Mefv	Mediterranean fever	0.022
Tyrobp	TYRO protein tyrosine kinase binding protein	0.022
Pten	phosphatase and tensin homolog	0.022
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.021
Gna15	guanine nucleotide binding protein, alpha 15	0.021
Grb2	growth factor receptor bound protein 2	0.021
Sell	selectin, lymphocyte	0.020
Il1a	interleukin 1 alpha	0.020
Fpr2	formyl peptide receptor 2	0.019
Fam83h	family with sequence similarity 83, member H	0.019
Pax8	paired box gene 8	0.019
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.019
Slfn4	schlafen 4	0.018
Il27ra	interleukin 27 receptor, alpha	0.018
Lcp1	lymphocyte cytosolic protein 1	0.018
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.018
Il18rap	interleukin 18 receptor accessory protein	0.018
Lrmp	lymphoid-restricted membrane protein	0.017
Vpreb3	pre-B lymphocyte gene 3	0.017
Cd79b	CD79B antigen	0.017
Nlrp3	NLR family, pyrin domain containing 3	0.017
Asprv1	aspartic peptidase, retroviral-like 1	0.017
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.017
Fasl	Fas ligand (TNF superfamily, member 6)	0.017
Il10	interleukin 10	0.017
Cd38	CD38 antigen	0.017
Hmha1	histocompatibility (minor) HA-1	0.017
Il1rn	interleukin 1 receptor antagonist	0.016
Cd3e	CD3 antigen, epsilon polypeptide	0.016
Samd4b	sterile alpha motif domain containing 4B	0.016
H2-Oa	histocompatibility 2, O region alpha locus	0.016
Ncf4	neutrophil cytosolic factor 4	0.016
Ccr7	chemokine (C-C motif) receptor 7	0.016
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.016
Il1b	interleukin 1 beta	0.016
Gzmk	granzyme K	0.016
Ly9	lymphocyte antigen 9	0.016
Itgb7	integrin beta 7	0.016
Cr2	complement receptor 2	0.016
Arhgap9	Rho GTPase activating protein 9	0.015
Cldn4	claudin 4	0.015
Fcrla	Fc receptor-like A	0.015
Clec4d	C-type lectin domain family 4, member d	0.015
Adcy7	adenylate cyclase 7	0.015
Itk	IL2-inducible T-cell kinase	0.015
Psapl1	prosaposin-like 1	0.015
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.015
Ifitm6	interferon induced transmembrane protein 6	0.015
Kit	kit oncogene	0.015
Gzmb	granzyme B	0.015
Lyz2	lysozyme 2	0.015
Cd160	CD160 antigen	0.015
Cd86	CD86 antigen	0.014
Apobr	apolipoprotein B receptor	0.014
Mrc1	mannose receptor, C type 1	0.014
Stat4	signal transducer and activator of transcription 4	0.014
Prdm1	PR domain containing 1, with ZNF domain	0.014
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.014
Il15	interleukin 15	0.014
H2-Ob	histocompatibility 2, O region beta locus	0.014
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.014
Cd3d	CD3 antigen, delta polypeptide	0.014
Rel	reticuloendotheliosis oncogene	0.014
Ifnar1	interferon (alpha and beta) receptor 1	0.014
Ubd	ubiquitin D	0.014
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.014
Ptpra	protein tyrosine phosphatase, receptor type, A	0.014
Fut7	fucosyltransferase 7	0.014
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.013
Tcra	T-cell receptor alpha chain	0.013
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.013
Pla2g2d	phospholipase A2, group IID	0.013
Cd300ld	CD300 molecule-like family member d	0.013
Ebi3	Epstein-Barr virus induced gene 3	0.013
Ptprj	protein tyrosine phosphatase, receptor type, J	0.013
Cd6	CD6 antigen	0.013
Foxb1	forkhead box B1	0.013
Clec7a	C-type lectin domain family 7, member a	0.013
Plaur	plasminogen activator, urokinase receptor	0.013
Slamf8	SLAM family member 8	0.013
Rag1	recombination activating gene 1	0.013
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.013
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.013
Cnr2	cannabinoid receptor 2 (macrophage)	0.013
Gpr132	G protein-coupled receptor 132	0.013
Efs	embryonal Fyn-associated substrate	0.013
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.013
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.013
Cxcr6	chemokine (C-X-C motif) receptor 6	0.012
Hmox1	heme oxygenase (decycling) 1	0.012
Tmprss2	transmembrane protease, serine 2	0.012
Dock2	dedicator of cyto-kinesis 2	0.012
Sh2d2a	SH2 domain protein 2A	0.012
Il10ra	interleukin 10 receptor, alpha	0.012
Nkg7	natural killer cell group 7 sequence	0.012
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.012
Stap1	signal transducing adaptor family member 1	0.012
Plek	pleckstrin	0.012
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.012
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.012
Pilra	paired immunoglobin-like type 2 receptor alpha	0.012
Tlr4	toll-like receptor 4	0.012
Fcgr4	Fc receptor, IgG, low affinity IV	0.012
Krt6a	keratin 6A	0.012
Xiap	X-linked inhibitor of apoptosis	0.012
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.012
Prss30	protease, serine, 30	0.012
Spn	sialophorin	0.012
Diap1	diaphanous homolog 1 (Drosophila)	0.012
Elf3	E74-like factor 3	0.011
Mmp9	matrix metallopeptidase 9	0.011
Cd52	CD52 antigen	0.011
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.011
Ly6d	lymphocyte antigen 6 complex, locus D	0.011
Cd244	CD244 natural killer cell receptor 2B4	0.011
Jak3	Janus kinase 3	0.011
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.011
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.011
Dok3	docking protein 3	0.011
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.011
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.011
Tlr2	toll-like receptor 2	0.011
Sla	src-like adaptor	0.011
Sfpi1	SFFV proviral integration 1	0.011
Ncf1	neutrophil cytosolic factor 1	0.011
Irg1	immunoresponsive gene 1	0.011
Kctd12	potassium channel tetramerisation domain containing 12	0.011
Pld4	phospholipase D family, member 4	0.011
Tbx21	T-box 21	0.011
Gzma	granzyme A	0.011
Cst7	cystatin F (leukocystatin)	0.011
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.011
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.011
Prf1	perforin 1 (pore forming protein)	0.011
Gpr35	G protein-coupled receptor 35	0.010
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.010
Stra8	stimulated by retinoic acid gene 8	0.010
Hhex	hematopoietically expressed homeobox	0.010
Skap2	src family associated phosphoprotein 2	0.010
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.010
Slc25a45	solute carrier family 25, member 45	0.010
Pou2f2	POU domain, class 2, transcription factor 2	0.010
S1pr3	sphingosine-1-phosphate receptor 3	0.010
Slamf1	signaling lymphocytic activation molecule family member 1	0.010
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.010
Nckap1l	NCK associated protein 1 like	0.010
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.010
2310014H01Rik	RIKEN cDNA 2310014H01 gene	0.010
Car6	carbonic anhydrase 6	0.010
Gpr18	G protein-coupled receptor 18	0.010
Tifa	TRAF-interacting protein with forkhead-associated domain	0.010
Tlr6	toll-like receptor 6	0.010
Plekhg6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.010