IMP

Process View

Mus musculus

2 genes annotated in mouse

proepicardium development

The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "proepicardium development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "proepicardium development" (in gray)

Name	Description	Probability	Func Analog Organism
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	1.000
Shh	sonic hedgehog	0.999
Hand1	heart and neural crest derivatives expressed transcript 1	0.995
Hand2	heart and neural crest derivatives expressed transcript 2	0.991	Zebrafish
Fgf8	fibroblast growth factor 8	0.978
Gata4	GATA binding protein 4	0.958
Fgfr2	fibroblast growth factor receptor 2	0.929
Sox9	SRY-box containing gene 9	0.853
Tbx1	T-box 1	0.827
Foxc2	forkhead box C2	0.808
Tgfb2	transforming growth factor, beta 2	0.731
Mesp1	mesoderm posterior 1	0.685
Pitx2	paired-like homeodomain transcription factor 2	0.615
Msx1	homeobox, msh-like 1	0.613
Gata6	GATA binding protein 6	0.608
Tbx3	T-box 3	0.585
Gja5	gap junction protein, alpha 5	0.580
Foxc1	forkhead box C1	0.560
Nkx3-2	NK3 homeobox 2	0.556	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.507
Tbx5	T-box 5	0.457	Zebrafish
Tcfap2a	transcription factor AP-2, alpha	0.438
Scn5a	sodium channel, voltage-gated, type V, alpha	0.411
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.409
Rxra	retinoid X receptor alpha	0.356
Chrd	chordin	0.347
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.327
Gli2	GLI-Kruppel family member GLI2	0.292
Gsc	goosecoid homeobox	0.265
Prrx1	paired related homeobox 1	0.205
Tgfbr2	transforming growth factor, beta receptor II	0.199
Pax3	paired box gene 3	0.185
Bmp7	bone morphogenetic protein 7	0.184
Vegfa	vascular endothelial growth factor A	0.167
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.165
Bmp4	bone morphogenetic protein 4	0.163	Zebrafish
Nog	noggin	0.161
Prrx2	paired related homeobox 2	0.158
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.153	Mouse
Pitx1	paired-like homeodomain transcription factor 1	0.152
Rarg	retinoic acid receptor, gamma	0.150
Rara	retinoic acid receptor, alpha	0.145
Col2a1	collagen, type II, alpha 1	0.133
Vax1	ventral anterior homeobox containing gene 1	0.128
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.127
Smo	smoothened homolog (Drosophila)	0.125
Nkx6-1	NK6 homeobox 1	0.122
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.116
Isl1	ISL1 transcription factor, LIM/homeodomain	0.116
Alx3	aristaless-like homeobox 3	0.109
Junb	Jun-B oncogene	0.108
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.105	Mouse
Otp	orthopedia homolog (Drosophila)	0.105
Pitx3	paired-like homeodomain transcription factor 3	0.103
Foxe3	forkhead box E3	0.102
Pax9	paired box gene 9	0.098
Ednra	endothelin receptor type A	0.097
Tcf21	transcription factor 21	0.080
Barx1	BarH-like homeobox 1	0.076
Lmx1b	LIM homeobox transcription factor 1 beta	0.075
Acvr1	activin A receptor, type 1	0.073
Ighmbp2	immunoglobulin mu binding protein 2	0.070
Hoxa1	homeobox A1	0.067
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.066
Runx2	runt related transcription factor 2	0.061
Alx4	aristaless-like homeobox 4	0.061
Hes2	hairy and enhancer of split 2 (Drosophila)	0.060
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.059
Gipc3	GIPC PDZ domain containing family, member 3	0.058
Hoxd12	homeobox D12	0.058
Fgf3	fibroblast growth factor 3	0.057
Pcdh12	protocadherin 12	0.057
Jag1	jagged 1	0.052
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.051
Wnt3a	wingless-related MMTV integration site 3A	0.051
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.049
Wnt6	wingless-related MMTV integration site 6	0.049
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.048
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.048	Mouse
Gli3	GLI-Kruppel family member GLI3	0.048
Znrf4	zinc and ring finger 4	0.046
Fgfr3	fibroblast growth factor receptor 3	0.045
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.045
Odf3	outer dense fiber of sperm tails 3	0.044
Bdkrb2	bradykinin receptor, beta 2	0.044
Otx2	orthodenticle homolog 2 (Drosophila)	0.044
Klf3	Kruppel-like factor 3 (basic)	0.043
Amh	anti-Mullerian hormone	0.043
Foxf1a	forkhead box F1a	0.043
Dlx5	distal-less homeobox 5	0.042
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.042
BC057022	cDNA sequence BC057022	0.042
Socs1	suppressor of cytokine signaling 1	0.042
Dusp1	dual specificity phosphatase 1	0.042
Adam17	a disintegrin and metallopeptidase domain 17	0.040
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.040
Zeb1	zinc finger E-box binding homeobox 1	0.039
4930527J03Rik	RIKEN cDNA 4930527J03 gene	0.039
Tcf15	transcription factor 15	0.039
Dlx6	distal-less homeobox 6	0.039
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.039
Ager	advanced glycosylation end product-specific receptor	0.039
Tssk1	testis-specific serine kinase 1	0.038
Npas1	neuronal PAS domain protein 1	0.038
Hoxd11	homeobox D11	0.037
Myl3	myosin, light polypeptide 3	0.037
Omp	olfactory marker protein	0.037
Tlx2	T-cell leukemia, homeobox 2	0.036
Fgf16	fibroblast growth factor 16	0.036
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.036	Mouse
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.036
Gh	growth hormone	0.035
Mybpc3	myosin binding protein C, cardiac	0.034
Ntf3	neurotrophin 3	0.034
Fos	FBJ osteosarcoma oncogene	0.034
Ribc2	RIB43A domain with coiled-coils 2	0.033
Btg2	B-cell translocation gene 2, anti-proliferative	0.033
Spdef	SAM pointed domain containing ets transcription factor	0.032
Bmp2	bone morphogenetic protein 2	0.032
Kcnk3	potassium channel, subfamily K, member 3	0.032
Hoxa13	homeobox A13	0.031
Fgf17	fibroblast growth factor 17	0.030
Gp9	glycoprotein 9 (platelet)	0.030
Ece1	endothelin converting enzyme 1	0.030
Rhox6	reproductive homeobox 6	0.029
Rax	retina and anterior neural fold homeobox	0.029
Hist1h1t	histone cluster 1, H1t	0.029
Hes3	hairy and enhancer of split 3 (Drosophila)	0.029
Sct	secretin	0.029
Gata5	GATA binding protein 5	0.029
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.029
Wnt11	wingless-related MMTV integration site 11	0.028
Ucn	urocortin	0.028
Tlx3	T-cell leukemia, homeobox 3	0.027
Klf6	Kruppel-like factor 6	0.027
Ptk7	PTK7 protein tyrosine kinase 7	0.027
Lhx3	LIM homeobox protein 3	0.026
Xirp1	xin actin-binding repeat containing 1	0.026
Spert	spermatid associated	0.026
Neurog1	neurogenin 1	0.026
Atoh7	atonal homolog 7 (Drosophila)	0.026
Evx2	even skipped homeotic gene 2 homolog	0.026
Pthlh	parathyroid hormone-like peptide	0.025
Cort	cortistatin	0.025
Snai1	snail homolog 1 (Drosophila)	0.025
Galr3	galanin receptor 3	0.024
Fgf22	fibroblast growth factor 22	0.024
Hoxd3	homeobox D3	0.024
Sycn	syncollin	0.024
Etv2	ets variant gene 2	0.024
Hoxb13	homeobox B13	0.024
Btg1	B-cell translocation gene 1, anti-proliferative	0.024
Gip	gastric inhibitory polypeptide	0.023
Bmper	BMP-binding endothelial regulator	0.023
Sox4	SRY-box containing gene 4	0.023
Utf1	undifferentiated embryonic cell transcription factor 1	0.023
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.023
Hdac7	histone deacetylase 7	0.023
Klf2	Kruppel-like factor 2 (lung)	0.023
Sall4	sal-like 4 (Drosophila)	0.023
Foxb2	forkhead box B2	0.022
Hoxd13	homeobox D13	0.022
Foxa2	forkhead box A2	0.022
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.021
Eya1	eyes absent 1 homolog (Drosophila)	0.021
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.021
2810449G22Rik	RIKEN cDNA 2810449G22 gene	0.021
Cdx1	caudal type homeobox 1	0.021
Cabp2	calcium binding protein 2	0.021
Grid2ip	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1	0.020
Mdfi	MyoD family inhibitor	0.020
Klf4	Kruppel-like factor 4 (gut)	0.020
Bmp10	bone morphogenetic protein 10	0.020
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.020
Art5	ADP-ribosyltransferase 5	0.020
Pou2f2	POU domain, class 2, transcription factor 2	0.020
Sfrp5	secreted frizzled-related sequence protein 5	0.020
Gja1	gap junction protein, alpha 1	0.020
Twist2	twist homolog 2 (Drosophila)	0.019
Bmp8b	bone morphogenetic protein 8b	0.019
Rtn4r	reticulon 4 receptor	0.019
Pim3	proviral integration site 3	0.019
Mzf1	myeloid zinc finger 1	0.019
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.019
Pyy	peptide YY	0.019
Tead3	TEA domain family member 3	0.019
Prss29	protease, serine, 29	0.019
Rsph6a	radial spoke head 6 homolog A (Chlamydomonas)	0.019
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.019
Nrtn	neurturin	0.019
Msx2	homeobox, msh-like 2	0.018
1700011A15Rik	RIKEN cDNA 1700011A15 gene	0.018
Shank1	SH3/ankyrin domain gene 1	0.018
Hmx1	H6 homeobox 1	0.018
Foxb1	forkhead box B1	0.018
6030468B19Rik	RIKEN cDNA 6030468B19 gene	0.018
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.018
Myl7	myosin, light polypeptide 7, regulatory	0.018
Sftpb	surfactant associated protein B	0.018
Smad6	MAD homolog 6 (Drosophila)	0.018
Zscan2	zinc finger and SCAN domain containing 2	0.018
Pdx1	pancreatic and duodenal homeobox 1	0.018
Zfpm2	zinc finger protein, multitype 2	0.018
Prm1	protamine 1	0.018
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.018
Fam65c	family with sequence similarity 65, member C	0.018
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.018
Chst3	carbohydrate (chondroitin 6/keratan) sulfotransferase 3	0.017
Des	desmin	0.017
Nodal	nodal	0.017
Onecut3	one cut domain, family member 3	0.017
Rarb	retinoic acid receptor, beta	0.017
Nobox	NOBOX oogenesis homeobox	0.017
Nos3	nitric oxide synthase 3, endothelial cell	0.017
Foxg1	forkhead box G1	0.017
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.017
Cyr61	cysteine rich protein 61	0.016
Guca2b	guanylate cyclase activator 2b (retina)	0.016
4930404N11Rik	RIKEN cDNA 4930404N11 gene	0.016
Fgf10	fibroblast growth factor 10	0.016
Foxd2	forkhead box D2	0.016
Egr4	early growth response 4	0.016
Foxl2	forkhead box L2	0.016
Dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b	0.016
1700029H14Rik	RIKEN cDNA 1700029H14 gene	0.016
Krt15	keratin 15	0.016
Gab2	growth factor receptor bound protein 2-associated protein 2	0.016
Gjc2	gap junction protein, gamma 2	0.016
Defa-rs12	defensin, alpha, related sequence 12	0.016
Mxd1	MAX dimerization protein 1	0.016
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.015
Ppy	pancreatic polypeptide	0.015
Efnb2	ephrin B2	0.015
Zfp771	zinc finger protein 771	0.015
Fgf15	fibroblast growth factor 15	0.015
Fut7	fucosyltransferase 7	0.015
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.015
Msgn1	mesogenin 1	0.015
Ms4a15	membrane-spanning 4-domains, subfamily A, member 15	0.015
Hoxa7	homeobox A7	0.015
1700008P20Rik	RIKEN cDNA 1700008P20 gene	0.015
Crybb2	crystallin, beta B2	0.014
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.014
Bhlhe23	basic helix-loop-helix family, member e23	0.014
Avp	arginine vasopressin	0.014
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.014
Kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.014
Tbx20	T-box 20	0.014
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.014
Bcl3	B-cell leukemia/lymphoma 3	0.014
Oc90	otoconin 90	0.014
Pth2	parathyroid hormone 2	0.014
Dmrtb1	DMRT-like family B with proline-rich C-terminal, 1	0.014
Krt17	keratin 17	0.014
Rhcg	Rhesus blood group-associated C glycoprotein	0.014
Tnf	tumor necrosis factor	0.014
Btbd17	BTB (POZ) domain containing 17	0.014
4921517D21Rik	RIKEN cDNA 4921517D21 gene	0.014
Gja3	gap junction protein, alpha 3	0.014
Popdc2	popeye domain containing 2	0.014
Sox3	SRY-box containing gene 3	0.014
Slurp1	secreted Ly6/Plaur domain containing 1	0.013
Clec3b	C-type lectin domain family 3, member b	0.013
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.013
Cmklr1	chemokine-like receptor 1	0.013
Cd40	CD40 antigen	0.013
Ccr10	chemokine (C-C motif) receptor 10	0.013
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.013
Dmbx1	diencephalon/mesencephalon homeobox 1	0.013
Mn1	meningioma 1	0.013
Wnt2b	wingless related MMTV integration site 2b	0.013
Lactbl1	lactamase, beta-like 1	0.013
Cldn3	claudin 3	0.013
Cela2a	chymotrypsin-like elastase family, member 2A	0.013
T	brachyury	0.013
Gdf15	growth differentiation factor 15	0.013
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.013
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.012
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.012
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.012
Tctex1d4	Tctex1 domain containing 4	0.012
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.012
Barx2	BarH-like homeobox 2	0.012
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.012
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.012
Ier2	immediate early response 2	0.012
Cela3b	chymotrypsin-like elastase family, member 3B	0.012
Zbtb7c	zinc finger and BTB domain containing 7C	0.012
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.012
Adra2b	adrenergic receptor, alpha 2b	0.012
Foxl1	forkhead box L1	0.012
Gdnf	glial cell line derived neurotrophic factor	0.012
Fgf4	fibroblast growth factor 4	0.012
Ivl	involucrin	0.012
Gpr27	G protein-coupled receptor 27	0.012
Dusp13	dual specificity phosphatase 13	0.012
Hmha1	histocompatibility (minor) HA-1	0.012
Rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.012
Neurog3	neurogenin 3	0.012
Fgf9	fibroblast growth factor 9	0.012
Spata3	spermatogenesis associated 3	0.012
Gas1	growth arrest specific 1	0.012
Adra1b	adrenergic receptor, alpha 1b	0.011
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.011
Chrm4	cholinergic receptor, muscarinic 4	0.011
Capn9	calpain 9	0.011
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.011
Jup	junction plakoglobin	0.011
Krt16	keratin 16	0.011
Egfr	epidermal growth factor receptor	0.011
Atf3	activating transcription factor 3	0.011
Sox18	SRY-box containing gene 18	0.011
Glis1	GLIS family zinc finger 1	0.011
Edn3	endothelin 3	0.011
Pax1	paired box gene 1	0.011
S1pr4	sphingosine-1-phosphate receptor 4	0.011
Kcng2	potassium voltage-gated channel, subfamily G, member 2	0.011
Gpc3	glypican 3	0.011
Lalba	lactalbumin, alpha	0.011
Papln	papilin, proteoglycan-like sulfated glycoprotein	0.011
Dnm2	dynamin 2	0.011
Hapln3	hyaluronan and proteoglycan link protein 3	0.011
Ctgf	connective tissue growth factor	0.011
Tmem210	transmembrane protein 210	0.011
Hoxc9	homeobox C9	0.011
Fgf18	fibroblast growth factor 18	0.011
Cxadr	coxsackie virus and adenovirus receptor	0.011
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.011
Bik	BCL2-interacting killer	0.011
Smad9	MAD homolog 9 (Drosophila)	0.010
Lmod1	leiomodin 1 (smooth muscle)	0.010
Ccna1	cyclin A1	0.010
Pax8	paired box gene 8	0.010
Foxe1	forkhead box E1	0.010
Meox2	mesenchyme homeobox 2	0.010
Tssk3	testis-specific serine kinase 3	0.010
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.010
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.010
Pax4	paired box gene 4	0.010
Padi1	peptidyl arginine deiminase, type I	0.010
BC024139	cDNA sequence BC024139	0.010
Tff3	trefoil factor 3, intestinal	0.010
Artn	artemin	0.010