IMP

Process View

Mus musculus

9 genes annotated in mouse

Multi-species View

tyrosine phosphorylation of stat5 protein

GO:0042506

The process of introducing a phosphate group to a tyrosine residue of a Stat5 protein.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tyrosine phosphorylation of stat5 protein"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "tyrosine phosphorylation of stat5 protein" (in gray)

Name	Description	Probability	Func Analog Organism
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	1.000
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.991	Mouse
Inpp5d	inositol polyphosphate-5-phosphatase D	0.989
Ptprc	protein tyrosine phosphatase, receptor type, C	0.958
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.928	Mouse
Ghr	growth hormone receptor	0.922
Esr1	estrogen receptor 1 (alpha)	0.918
Pten	phosphatase and tensin homolog	0.901
Stat3	signal transducer and activator of transcription 3	0.884
Cbl	Casitas B-lineage lymphoma	0.872
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.826	Mouse
Lepr	leptin receptor	0.824
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.756
Ifng	interferon gamma	0.749
Lck	lymphocyte protein tyrosine kinase	0.722
Nrg1	neuregulin 1	0.718
Ptk2	PTK2 protein tyrosine kinase 2	0.694
Csf1	colony stimulating factor 1 (macrophage)	0.690
Fyn	Fyn proto-oncogene	0.658	Mouse
Il2rg	interleukin 2 receptor, gamma chain	0.645
Jak2	Janus kinase 2	0.614
Il4	interleukin 4	0.609
Kit	kit oncogene	0.528	Human
Grb2	growth factor receptor bound protein 2	0.520
Cav1	caveolin 1, caveolae protein	0.448
Nos3	nitric oxide synthase 3, endothelial cell	0.426
Stat5a	signal transducer and activator of transcription 5A	0.403
Tcra	T-cell receptor alpha chain	0.355
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.354
Tnf	tumor necrosis factor	0.340
Esr2	estrogen receptor 2 (beta)	0.315
Ret	ret proto-oncogene	0.312
S1pr1	sphingosine-1-phosphate receptor 1	0.304
Nf1	neurofibromatosis 1	0.299
Il2rb	interleukin 2 receptor, beta chain	0.290
Dok2	docking protein 2	0.287
Kitl	kit ligand	0.285
Was	Wiskott-Aldrich syndrome homolog (human)	0.284
Pparg	peroxisome proliferator activated receptor gamma	0.280
Egfr	epidermal growth factor receptor	0.274	Mouse
Dok1	docking protein 1	0.270
Hif1a	hypoxia inducible factor 1, alpha subunit	0.243
Apoe	apolipoprotein E	0.242
Csf1r	colony stimulating factor 1 receptor	0.238
Plcg2	phospholipase C, gamma 2	0.220
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.211
Pou2af1	POU domain, class 2, associating factor 1	0.208
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.196
Dmd	dystrophin, muscular dystrophy	0.186
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.177
Cd247	CD247 antigen	0.169
Rag1	recombination activating gene 1	0.166
Lif	leukemia inhibitory factor	0.156
Apc	adenomatosis polyposis coli	0.152
Stat5b	signal transducer and activator of transcription 5B	0.151
Fyb	FYN binding protein	0.150
Phox2b	paired-like homeobox 2b	0.148
Ntf3	neurotrophin 3	0.147
Il10	interleukin 10	0.144
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.138
Blnk	B-cell linker	0.133
Col1a1	collagen, type I, alpha 1	0.125
Tsc1	tuberous sclerosis 1	0.115
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.114
Il6st	interleukin 6 signal transducer	0.103
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.102
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.101	Human
Ptpre	protein tyrosine phosphatase, receptor type, E	0.097
Ccr6	chemokine (C-C motif) receptor 6	0.097
Tek	endothelial-specific receptor tyrosine kinase	0.094
Ncoa3	nuclear receptor coactivator 3	0.090
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.090
Ptrf	polymerase I and transcript release factor	0.083
Mefv	Mediterranean fever	0.081
Prlr	prolactin receptor	0.080
Nsf	N-ethylmaleimide sensitive fusion protein	0.076
Ahr	aryl-hydrocarbon receptor	0.075
Il2	interleukin 2	0.069
Hcst	hematopoietic cell signal transducer	0.068
Cd40	CD40 antigen	0.068
Il25	interleukin 25	0.066
Insr	insulin receptor	0.064
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.064
Tsc2	tuberous sclerosis 2	0.058
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.053
Foxn1	forkhead box N1	0.051
Pxn	paxillin	0.051
Fas	Fas (TNF receptor superfamily member 6)	0.048
Rag2	recombination activating gene 2	0.048
Ctnnb1	catenin (cadherin associated protein), beta 1	0.047
Gja1	gap junction protein, alpha 1	0.047
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.045
Il12b	interleukin 12b	0.045
Tgfb1	transforming growth factor, beta 1	0.042
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.038
Slc20a1	solute carrier family 20, member 1	0.038
Rb1	retinoblastoma 1	0.038
Ifnar1	interferon (alpha and beta) receptor 1	0.037
Clnk	cytokine-dependent hematopoietic cell linker	0.037
Epor	erythropoietin receptor	0.036
Vdr	vitamin D receptor	0.035
Sos1	son of sevenless homolog 1 (Drosophila)	0.035
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.033
Dsg2	desmoglein 2	0.032
Egr2	early growth response 2	0.032
Isl1	ISL1 transcription factor, LIM/homeodomain	0.032
Cd19	CD19 antigen	0.031
Cd160	CD160 antigen	0.030
Lmna	lamin A	0.030
Amhr2	anti-Mullerian hormone type 2 receptor	0.029
Ccl4	chemokine (C-C motif) ligand 4	0.029
Socs3	suppressor of cytokine signaling 3	0.029
Bdnf	brain derived neurotrophic factor	0.028
Ikzf1	IKAROS family zinc finger 1	0.028
Rasa1	RAS p21 protein activator 1	0.027
Jak1	Janus kinase 1	0.027	Mouse
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.025
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.024
Foxp3	forkhead box P3	0.024
Prf1	perforin 1 (pore forming protein)	0.024
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.024
Numb	numb gene homolog (Drosophila)	0.023
Hcls1	hematopoietic cell specific Lyn substrate 1	0.023
Adam17	a disintegrin and metallopeptidase domain 17	0.023
Cd22	CD22 antigen	0.023
Smad4	MAD homolog 4 (Drosophila)	0.023
Dok3	docking protein 3	0.023
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.022
Npc1	Niemann Pick type C1	0.022
Hoxa1	homeobox A1	0.022
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.022
Vegfa	vascular endothelial growth factor A	0.022
Thra	thyroid hormone receptor alpha	0.022
Errfi1	ERBB receptor feedback inhibitor 1	0.022
Cd28	CD28 antigen	0.022
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.021
Sh2d2a	SH2 domain protein 2A	0.020
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.020
Mrc1	mannose receptor, C type 1	0.020
Kiss1	KiSS-1 metastasis-suppressor	0.019
Diap1	diaphanous homolog 1 (Drosophila)	0.019
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.019	Mouse
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.019
Sh3kbp1	SH3-domain kinase binding protein 1	0.019
Spna1	spectrin alpha 1	0.018
Src	Rous sarcoma oncogene	0.018	Mouse
Trp53	transformation related protein 53	0.018
Kl	klotho	0.018
Tlr2	toll-like receptor 2	0.018
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.018
Cd40lg	CD40 ligand	0.018
Il15	interleukin 15	0.017
Prkce	protein kinase C, epsilon	0.017
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.017
Ptpra	protein tyrosine phosphatase, receptor type, A	0.016
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.016
Mapk8	mitogen-activated protein kinase 8	0.016
Rac1	RAS-related C3 botulinum substrate 1	0.015
Il12rb1	interleukin 12 receptor, beta 1	0.015
Lep	leptin	0.014
Ntf5	neurotrophin 5	0.014
Hk1	hexokinase 1	0.014
Smn1	survival motor neuron 1	0.014
Fshr	follicle stimulating hormone receptor	0.014
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.014
Fcgr1	Fc receptor, IgG, high affinity I	0.014
Pax8	paired box gene 8	0.014
Fpr1	formyl peptide receptor 1	0.014
Nos2	nitric oxide synthase 2, inducible	0.014
Rhoj	ras homolog gene family, member J	0.013
Rel	reticuloendotheliosis oncogene	0.013
Rac2	RAS-related C3 botulinum substrate 2	0.013
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.013
Chd7	chromodomain helicase DNA binding protein 7	0.013
Fasl	Fas ligand (TNF superfamily, member 6)	0.013
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.013
Skap2	src family associated phosphoprotein 2	0.013
Pcdh12	protocadherin 12	0.013
Lama4	laminin, alpha 4	0.012
Axl	AXL receptor tyrosine kinase	0.012
Soat2	sterol O-acyltransferase 2	0.012
Pvrl3	poliovirus receptor-related 3	0.012
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.012
Spn	sialophorin	0.012
Ap3b1	adaptor-related protein complex 3, beta 1 subunit	0.012
Cd38	CD38 antigen	0.012
She	src homology 2 domain-containing transforming protein E	0.012
Jak3	Janus kinase 3	0.012	Mouse Rat
Efnb2	ephrin B2	0.012
Ugcg	UDP-glucose ceramide glucosyltransferase	0.011
Rint1	RAD50 interactor 1	0.011
Foxa2	forkhead box A2	0.011
Lyz2	lysozyme 2	0.011
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.011
Tbx21	T-box 21	0.011
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.011
Prss32	protease, serine, 32	0.011
Ar	androgen receptor	0.011
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.011
Stat6	signal transducer and activator of transcription 6	0.011
Ggta1	glycoprotein galactosyltransferase alpha 1, 3	0.011
Hgfac	hepatocyte growth factor activator	0.010
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.010
Meox2	mesenchyme homeobox 2	0.010
Smad1	MAD homolog 1 (Drosophila)	0.010
Cish	cytokine inducible SH2-containing protein	0.010
Mmp9	matrix metallopeptidase 9	0.010
Bcar1	breast cancer anti-estrogen resistance 1	0.010