IMP

Process View

Mus musculus

13 genes annotated in mouse

disruption of cells of other organism involved in symbiotic interaction

A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "disruption of cells of other organism involved in symbiotic interaction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "disruption of cells of other organism involved in symbiotic interaction" (in gray)

Name	Description	Probability	Func Analog Organism
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.707
Elane	elastase, neutrophil expressed	0.624
Ngp	neutrophilic granule protein	0.547	Mouse
Ctsg	cathepsin G	0.532
Mpo	myeloperoxidase	0.456
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.399
Gzmb	granzyme B	0.339	Mouse
Mmp8	matrix metallopeptidase 8	0.307
Cxcl1	chemokine (C-X-C motif) ligand 1	0.279
Cxcl2	chemokine (C-X-C motif) ligand 2	0.251	Mouse
Cma1	chymase 1, mast cell	0.250	Mouse
Cpa3	carboxypeptidase A3, mast cell	0.230
Ccl7	chemokine (C-C motif) ligand 7	0.223
Mcpt2	mast cell protease 2	0.192	Mouse
LOC100504404	h-2 class II histocompatibility antigen, E-K alpha chain-like	0.183
Gzmf	granzyme F	0.165	Mouse
Prg2	proteoglycan 2, bone marrow	0.163
Camp	cathelicidin antimicrobial peptide	0.156
Il18rap	interleukin 18 receptor accessory protein	0.136
Cma2	chymase 2, mast cell	0.130
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.130
Gbp1	guanylate binding protein 1	0.127
Gzmd	granzyme D	0.125	Mouse
Mcpt4	mast cell protease 4	0.122	Mouse
Selp	selectin, platelet	0.105
Fasl	Fas ligand (TNF superfamily, member 6)	0.095
Ccl4	chemokine (C-C motif) ligand 4	0.093
Fcer1a	Fc receptor, IgE, high affinity I, alpha polypeptide	0.091
Il1r2	interleukin 1 receptor, type II	0.089
Iigp1	interferon inducible GTPase 1	0.080
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.078
Ccl8	chemokine (C-C motif) ligand 8	0.077
Prtn3	proteinase 3	0.077	Mouse
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.073
Folr2	folate receptor 2 (fetal)	0.073
Clec4e	C-type lectin domain family 4, member e	0.073
H2-M9	histocompatibility 2, M region locus 9	0.072
Ms4a3	membrane-spanning 4-domains, subfamily A, member 3	0.072
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.070
Niacr1	niacin receptor 1	0.067
Trem3	triggering receptor expressed on myeloid cells 3	0.066
Ccl5	chemokine (C-C motif) ligand 5	0.064
Ltf	lactotransferrin	0.064
Prol1	proline rich, lacrimal 1	0.063
Ubd	ubiquitin D	0.062
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.061
Cxcl10	chemokine (C-X-C motif) ligand 10	0.059	Mouse
Il1b	interleukin 1 beta	0.059
Slpi	secretory leukocyte peptidase inhibitor	0.058
Irg1	immunoresponsive gene 1	0.058
Gzmc	granzyme C	0.058	Mouse
Mapk3	mitogen-activated protein kinase 3	0.058
Il1rn	interleukin 1 receptor antagonist	0.058
Gp1ba	glycoprotein 1b, alpha polypeptide	0.056
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.055
Mcpt8	mast cell protease 8	0.054	Mouse
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.053
Sva	seminal vesicle antigen	0.053
Mmp13	matrix metallopeptidase 13	0.053
Gdf15	growth differentiation factor 15	0.052
Gzma	granzyme A	0.051	Mouse
Akr1c6	aldo-keto reductase family 1, member C6	0.050
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.049
Cidec	cell death-inducing DFFA-like effector c	0.048
Batf	basic leucine zipper transcription factor, ATF-like	0.047
Xcl1	chemokine (C motif) ligand 1	0.047
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.046
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.046
Nkg7	natural killer cell group 7 sequence	0.045
Ccl12	chemokine (C-C motif) ligand 12	0.044
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.044
Ctsw	cathepsin W	0.042
Fcgr1	Fc receptor, IgG, high affinity I	0.041
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.041
Ang2	angiogenin, ribonuclease A family, member 2	0.041
Tcrd	T-cell receptor delta chain	0.040
C2	complement component 2 (within H-2S)	0.040
Bcl2	B-cell leukemia/lymphoma 2	0.039
Fcna	ficolin A	0.039
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.039
Cxcr2	chemokine (C-X-C motif) receptor 2	0.036
Trim10	tripartite motif-containing 10	0.036
Umod	uromodulin	0.035
Gfi1b	growth factor independent 1B	0.035
Prl2b1	prolactin family 2, subfamily b, member 1	0.035
Mup4	major urinary protein 4	0.035
Omt2b	oocyte maturation, beta	0.034
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.034
Ccl11	chemokine (C-C motif) ligand 11	0.034
Sh2d2a	SH2 domain protein 2A	0.033
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.033
Retn	resistin	0.033
Tal1	T-cell acute lymphocytic leukemia 1	0.032
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.031
Ifng	interferon gamma	0.031
Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9	0.031
Prl7d1	prolactin family 7, subfamily d, member 1	0.030
Dpt	dermatopontin	0.028
Il2rb	interleukin 2 receptor, beta chain	0.028
Gzme	granzyme E	0.028	Mouse
Tnxb	tenascin XB	0.027
C5ar1	complement component 5a receptor 1	0.027
Hc	hemolytic complement	0.027
Mmp2	matrix metallopeptidase 2	0.027
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.027
Col14a1	collagen, type XIV, alpha 1	0.027
Ccl22	chemokine (C-C motif) ligand 22	0.026
Ifitm6	interferon induced transmembrane protein 6	0.026
Rag2	recombination activating gene 2	0.026
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.026
Atf3	activating transcription factor 3	0.026
Gpr97	G protein-coupled receptor 97	0.025
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.025
Cd3d	CD3 antigen, delta polypeptide	0.025
Il1rl1	interleukin 1 receptor-like 1	0.024
Itgb3	integrin beta 3	0.024
Nnmt	nicotinamide N-methyltransferase	0.024
Rsad2	radical S-adenosyl methionine domain containing 2	0.024
Mmp3	matrix metallopeptidase 3	0.024
Bcl2l1	BCL2-like 1	0.024
Ccl3	chemokine (C-C motif) ligand 3	0.024
Cst7	cystatin F (leukocystatin)	0.023
Plunc	palate, lung, and nasal epithelium associated	0.023
Ly6i	lymphocyte antigen 6 complex, locus I	0.023
Ltc4s	leukotriene C4 synthase	0.023
Ppbp	pro-platelet basic protein	0.023
Uts2r	urotensin 2 receptor	0.022
Chi3l1	chitinase 3-like 1	0.022
Stfa3	stefin A3	0.022
Cd80	CD80 antigen	0.021
Lmna	lamin A	0.021
Prl7a1	prolactin family 7, subfamily a, member 1	0.021
Ctse	cathepsin E	0.021
Apoh	apolipoprotein H	0.021
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.021
Aqp7	aquaporin 7	0.021
Mgmt	O-6-methylguanine-DNA methyltransferase	0.021
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.021
Rfpl4	ret finger protein-like 4	0.021
Gpr133	G protein-coupled receptor 133	0.021
Cryba1	crystallin, beta A1	0.021
Fpr2	formyl peptide receptor 2	0.021
Slamf8	SLAM family member 8	0.020
Il6	interleukin 6	0.020
Slfn4	schlafen 4	0.020
Mfap5	microfibrillar associated protein 5	0.020
Hemgn	hemogen	0.020
Lcn4	lipocalin 4	0.020
Plaur	plasminogen activator, urokinase receptor	0.019
Igtp	interferon gamma induced GTPase	0.019
Rhag	Rhesus blood group-associated A glycoprotein	0.019
Mucl1	mucin-like 1	0.018
Ddah2	dimethylarginine dimethylaminohydrolase 2	0.018
Car3	carbonic anhydrase 3	0.018
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.018
Ahsp	alpha hemoglobin stabilizing protein	0.018
Ighg	Immunoglobulin heavy chain (gamma polypeptide)	0.018
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.018
Cfi	complement component factor i	0.017
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.017
Glrp1	glutamine repeat protein 1	0.017
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.017
Cxcl9	chemokine (C-X-C motif) ligand 9	0.017	Mouse
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.017
F13a1	coagulation factor XIII, A1 subunit	0.017
Cldn13	claudin 13	0.017
Junb	Jun-B oncogene	0.017
Myf6	myogenic factor 6	0.017
Ager	advanced glycosylation end product-specific receptor	0.016
Spic	Spi-C transcription factor (Spi-1/PU.1 related)	0.016
Areg	amphiregulin	0.016
Svs6	seminal vesicle secretory protein 6	0.016
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.016
Adipoq	adiponectin, C1Q and collagen domain containing	0.016
Mpz	myelin protein zero	0.016
Itm2c	integral membrane protein 2C	0.016
Fabp4	fatty acid binding protein 4, adipocyte	0.016
Pi16	peptidase inhibitor 16	0.016
Kcnj8	potassium inwardly-rectifying channel, subfamily J, member 8	0.015
Clec4d	C-type lectin domain family 4, member d	0.015
Cd5l	CD5 antigen-like	0.015
S1pr4	sphingosine-1-phosphate receptor 4	0.015
Cd177	CD177 antigen	0.015
Cnn1	calponin 1	0.015
Rhd	Rh blood group, D antigen	0.015
Cd3e	CD3 antigen, epsilon polypeptide	0.015
Gpr35	G protein-coupled receptor 35	0.015
Otc	ornithine transcarbamylase	0.015
Pgk2	phosphoglycerate kinase 2	0.015
Rgs1	regulator of G-protein signaling 1	0.015
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.015
Chi3l3	chitinase 3-like 3	0.015
Ear11	eosinophil-associated, ribonuclease A family, member 11	0.014
Vsig4	V-set and immunoglobulin domain containing 4	0.014
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.014
Nfe2	nuclear factor, erythroid derived 2	0.014
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.014
Tnfrsf23	tumor necrosis factor receptor superfamily, member 23	0.014
Tpsb2	tryptase beta 2	0.014
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.014
Lipc	lipase, hepatic	0.014
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.014
Ccl17	chemokine (C-C motif) ligand 17	0.014
Pzp	pregnancy zone protein	0.014
Itgal	integrin alpha L	0.014
Tnip1	TNFAIP3 interacting protein 1	0.014
Alox15	arachidonate 15-lipoxygenase	0.014
Cox8b	cytochrome c oxidase, subunit VIIIb	0.014
Ermap	erythroblast membrane-associated protein	0.014
Gp9	glycoprotein 9 (platelet)	0.014
Ccl1	chemokine (C-C motif) ligand 1	0.014
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.014
Apof	apolipoprotein F	0.014
Artn	artemin	0.013
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.013
Gfi1	growth factor independent 1	0.013
Cd83	CD83 antigen	0.013
Tnni2	troponin I, skeletal, fast 2	0.013
Adrb3	adrenergic receptor, beta 3	0.013
Apoa1	apolipoprotein A-I	0.013
Naip1	NLR family, apoptosis inhibitory protein 1	0.013
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.013
Tgtp2	T-cell specific GTPase 2	0.013
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.013
Bdkrb1	bradykinin receptor, beta 1	0.013
Shox2	short stature homeobox 2	0.013
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.013
Cldn7	claudin 7	0.013
Mrap	melanocortin 2 receptor accessory protein	0.013
Cd209b	CD209b antigen	0.013
Ptgir	prostaglandin I receptor (IP)	0.013
Il3	interleukin 3	0.013
Mmp10	matrix metallopeptidase 10	0.012
Try5	trypsin 5	0.012
Eln	elastin	0.012
Tekt2	tektin 2	0.012
Uox	urate oxidase	0.012
Ccrl2	chemokine (C-C motif) receptor-like 2	0.012
Cd3g	CD3 antigen, gamma polypeptide	0.012
Fosl1	fos-like antigen 1	0.012
Chad	chondroadherin	0.012
Hdc	histidine decarboxylase	0.012
Sept1	septin 1	0.012
Kng1	kininogen 1	0.012
Cd209f	CD209f antigen	0.012
Myl9	myosin, light polypeptide 9, regulatory	0.012
Cd209a	CD209a antigen	0.011
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.011
Sh2d1b1	SH2 domain protein 1B1	0.011
Vav2	vav 2 oncogene	0.011
Ccl2	chemokine (C-C motif) ligand 2	0.011
P2ry4	pyrimidinergic receptor P2Y, G-protein coupled, 4	0.011
Tbx21	T-box 21	0.011
H2-Q7	histocompatibility 2, Q region locus 7	0.011
Saa3	serum amyloid A 3	0.011
Soat2	sterol O-acyltransferase 2	0.011
Cd7	CD7 antigen	0.011
Myh4	myosin, heavy polypeptide 4, skeletal muscle	0.011
Gbp2	guanylate binding protein 2	0.011
Ces1c	carboxylesterase 1C	0.011
Il12rb1	interleukin 12 receptor, beta 1	0.011
Mx2	myxovirus (influenza virus) resistance 2	0.011
Bmp5	bone morphogenetic protein 5	0.011
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.011
Tssk2	testis-specific serine kinase 2	0.011
Cxcl3	chemokine (C-X-C motif) ligand 3	0.010
Sult1c1	sulfotransferase family, cytosolic, 1C, member 1	0.010
Vcam1	vascular cell adhesion molecule 1	0.010
Klk1b26	kallikrein 1-related petidase b26	0.010
Cd300lf	CD300 antigen like family member F	0.010
Gpr84	G protein-coupled receptor 84	0.010
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.010
Gc	group specific component	0.010
F13b	coagulation factor XIII, beta subunit	0.010
Fbn1	fibrillin 1	0.010
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.010
Il2ra	interleukin 2 receptor, alpha chain	0.010
Hpx	hemopexin	0.010
Fabp2	fatty acid binding protein 2, intestinal	0.010
Tfpi2	tissue factor pathway inhibitor 2	0.010
Ifi47	interferon gamma inducible protein 47	0.010