IMP

Process View

Mus musculus

20 genes annotated in mouse

male genitalia development

The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "male genitalia development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "male genitalia development" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.997
Fgfr2	fibroblast growth factor receptor 2	0.989
Gli3	GLI-Kruppel family member GLI3	0.967
Pax8	paired box gene 8	0.938
Fgf8	fibroblast growth factor 8	0.862
Foxc1	forkhead box C1	0.794
Pax6	paired box gene 6	0.702
Pax2	paired box gene 2	0.688
Hoxd13	homeobox D13	0.668
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.654
Amhr2	anti-Mullerian hormone type 2 receptor	0.626
Fgf10	fibroblast growth factor 10	0.598
Sox9	SRY-box containing gene 9	0.533	Mouse
Fgfr3	fibroblast growth factor receptor 3	0.506
Ntf3	neurotrophin 3	0.491
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.489
Trp63	transformation related protein 63	0.448
Bmp4	bone morphogenetic protein 4	0.435
Ret	ret proto-oncogene	0.429
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.416
Nos3	nitric oxide synthase 3, endothelial cell	0.405
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.377
Hoxd11	homeobox D11	0.344
Nog	noggin	0.306
Ar	androgen receptor	0.303
Sall4	sal-like 4 (Drosophila)	0.291	Fly
Foxc2	forkhead box C2	0.290
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.288
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.246
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.239
Rarb	retinoic acid receptor, beta	0.216
Fgf9	fibroblast growth factor 9	0.215	Mouse
Gli2	GLI-Kruppel family member GLI2	0.208
Tbx15	T-box 15	0.208
Pitx2	paired-like homeodomain transcription factor 2	0.206
Tbx3	T-box 3	0.205	Human
Tcf21	transcription factor 21	0.191
Alx4	aristaless-like homeobox 4	0.184
Hoxa13	homeobox A13	0.180
Lmx1b	LIM homeobox transcription factor 1 beta	0.177
Meox2	mesenchyme homeobox 2	0.177
Tbx2	T-box 2	0.172
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.165	Worm
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.165	Worm
Pax3	paired box gene 3	0.161
Foxf2	forkhead box F2	0.148
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.145
Gdnf	glial cell line derived neurotrophic factor	0.145
Pou5f1	POU domain, class 5, transcription factor 1	0.139
Bmp7	bone morphogenetic protein 7	0.131	Mouse
Hoxa1	homeobox A1	0.125
Hand2	heart and neural crest derivatives expressed transcript 2	0.123
Gdf5	growth differentiation factor 5	0.114	Mouse
Vegfa	vascular endothelial growth factor A	0.114
Ctnnb1	catenin (cadherin associated protein), beta 1	0.109
Nab2	Ngfi-A binding protein 2	0.105
Fgfr1	fibroblast growth factor receptor 1	0.105
Kdr	kinase insert domain protein receptor	0.104	Mouse Fly
Hoxa10	homeobox A10	0.100
Hoxa11	homeobox A11	0.099
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.096	Fly
Wnt2b	wingless related MMTV integration site 2b	0.091	Mouse
Pou3f3	POU domain, class 3, transcription factor 3	0.090
Apc	adenomatosis polyposis coli	0.088
Pou3f1	POU domain, class 3, transcription factor 1	0.087
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.086
Pthlh	parathyroid hormone-like peptide	0.084
Kiss1	KiSS-1 metastasis-suppressor	0.082
Esrrb	estrogen related receptor, beta	0.082
Wnt3	wingless-related MMTV integration site 3	0.080	Mouse
Lhx1	LIM homeobox protein 1	0.079
Fgf18	fibroblast growth factor 18	0.079	Mouse
Pten	phosphatase and tensin homolog	0.076
Bcl2	B-cell leukemia/lymphoma 2	0.076
T	brachyury	0.076
Ybx2	Y box protein 2	0.076
Nkx2-1	NK2 homeobox 1	0.075
Fgf5	fibroblast growth factor 5	0.074	Mouse
Ptprb	protein tyrosine phosphatase, receptor type, B	0.067
Sall1	sal-like 1 (Drosophila)	0.066	Fly
Dmrt1	doublesex and mab-3 related transcription factor 1	0.062
Kl	klotho	0.062
Sox10	SRY-box containing gene 10	0.060	Mouse
Isl1	ISL1 transcription factor, LIM/homeodomain	0.058
Npr3	natriuretic peptide receptor 3	0.057
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.057
Twist2	twist homolog 2 (Drosophila)	0.057
Emx2	empty spiracles homolog 2 (Drosophila)	0.055
Tgfb2	transforming growth factor, beta 2	0.054
Msx2	homeobox, msh-like 2	0.053
Btbd17	BTB (POZ) domain containing 17	0.052
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.052
Hoxd9	homeobox D9	0.051
Gli1	GLI-Kruppel family member GLI1	0.051
Acan	aggrecan	0.050
Flt4	FMS-like tyrosine kinase 4	0.047	Mouse Fly
Wnt3a	wingless-related MMTV integration site 3A	0.046	Mouse
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.046
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.045
Gata3	GATA binding protein 3	0.044
Cbl	Casitas B-lineage lymphoma	0.044
Lrp6	low density lipoprotein receptor-related protein 6	0.044
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.044
Fzd8	frizzled homolog 8 (Drosophila)	0.043
Lepr	leptin receptor	0.042
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.041
Fshr	follicle stimulating hormone receptor	0.041	Mouse
Gata6	GATA binding protein 6	0.041
Pbx1	pre B-cell leukemia transcription factor 1	0.040
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.040
Cdx1	caudal type homeobox 1	0.040
Rxra	retinoid X receptor alpha	0.039
Epas1	endothelial PAS domain protein 1	0.039
Efnb2	ephrin B2	0.039
Emid2	EMI domain containing 2	0.039
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.038
Otx2	orthodenticle homolog 2 (Drosophila)	0.037
Flt1	FMS-like tyrosine kinase 1	0.036	Mouse Fly
Wnt9a	wingless-type MMTV integration site 9A	0.036	Mouse
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.036
Tcfap2a	transcription factor AP-2, alpha	0.036
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.036
Hand1	heart and neural crest derivatives expressed transcript 1	0.036
Zeb1	zinc finger E-box binding homeobox 1	0.036
She	src homology 2 domain-containing transforming protein E	0.035
Gata5	GATA binding protein 5	0.035
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.035
Tgfa	transforming growth factor alpha	0.035
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.035
Lrp2	low density lipoprotein receptor-related protein 2	0.034
Hes1	hairy and enhancer of split 1 (Drosophila)	0.034
Esr1	estrogen receptor 1 (alpha)	0.034
Efna4	ephrin A4	0.033
Npas1	neuronal PAS domain protein 1	0.032
Padi3	peptidyl arginine deiminase, type III	0.032
Bdkrb2	bradykinin receptor, beta 2	0.032
Pou3f4	POU domain, class 3, transcription factor 4	0.032
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.031
Pdgfb	platelet derived growth factor, B polypeptide	0.031
Phox2b	paired-like homeobox 2b	0.031
Zic3	zinc finger protein of the cerebellum 3	0.031
Amh	anti-Mullerian hormone	0.031
Sox3	SRY-box containing gene 3	0.031	Mouse
Fos	FBJ osteosarcoma oncogene	0.030
Nanog	Nanog homeobox	0.030
Wnt11	wingless-related MMTV integration site 11	0.030	Mouse
Gja3	gap junction protein, alpha 3	0.030
Sfrp2	secreted frizzled-related protein 2	0.030
Lhx3	LIM homeobox protein 3	0.029
Trp53	transformation related protein 53	0.029
Wt1	Wilms tumor 1 homolog	0.029
Smo	smoothened homolog (Drosophila)	0.029
Pitx1	paired-like homeodomain transcription factor 1	0.028
Angpt4	angiopoietin 4	0.027
Epha4	Eph receptor A4	0.027
Col4a3	collagen, type IV, alpha 3	0.027
Hoxa9	homeobox A9	0.027
Kitl	kit ligand	0.027
Nrg1	neuregulin 1	0.026
Cdh13	cadherin 13	0.026
Adra2b	adrenergic receptor, alpha 2b	0.026
Sox2	SRY-box containing gene 2	0.026
Tnni2	troponin I, skeletal, fast 2	0.026
Lama5	laminin, alpha 5	0.026
Lef1	lymphoid enhancer binding factor 1	0.026
Cxcl12	chemokine (C-X-C motif) ligand 12	0.026
Nkx3-2	NK3 homeobox 2	0.025
Smad6	MAD homolog 6 (Drosophila)	0.025
Sox17	SRY-box containing gene 17	0.025	Mouse
Tek	endothelial-specific receptor tyrosine kinase	0.025
Fut7	fucosyltransferase 7	0.025
Bcl6b	B-cell CLL/lymphoma 6, member B	0.024
Foxa2	forkhead box A2	0.024
Npr2	natriuretic peptide receptor 2	0.024
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.024
Fgf15	fibroblast growth factor 15	0.024
Eya4	eyes absent 4 homolog (Drosophila)	0.023
Hoxb6	homeobox B6	0.023
Cxadr	coxsackie virus and adenovirus receptor	0.023
Rarg	retinoic acid receptor, gamma	0.023
Vangl2	vang-like 2 (van gogh, Drosophila)	0.023
Esr2	estrogen receptor 2 (beta)	0.023
Prrx1	paired related homeobox 1	0.023
Nf1	neurofibromatosis 1	0.023
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.022
Kcns1	K+ voltage-gated channel, subfamily S, 1	0.022
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.022
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.022
Vegfc	vascular endothelial growth factor C	0.022
Hoxc9	homeobox C9	0.022
Foxb2	forkhead box B2	0.022
Foxe3	forkhead box E3	0.021
Barx1	BarH-like homeobox 1	0.021
Wnt10b	wingless related MMTV integration site 10b	0.021	Mouse
Sox18	SRY-box containing gene 18	0.021	Mouse
Ahr	aryl-hydrocarbon receptor	0.021
Robo3	roundabout homolog 3 (Drosophila)	0.021
Gata4	GATA binding protein 4	0.020
Col2a1	collagen, type II, alpha 1	0.020
Ikbkap	inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein	0.020
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.020
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.020
Slurp1	secreted Ly6/Plaur domain containing 1	0.020
Hoxd10	homeobox D10	0.020
Tcfap2c	transcription factor AP-2, gamma	0.020
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.020
Epha1	Eph receptor A1	0.020
Rem1	rad and gem related GTP binding protein 1	0.019
Tbx4	T-box 4	0.019
Rspo1	R-spondin homolog (Xenopus laevis)	0.019
Tsx	testis specific X-linked gene	0.019
Clcnka	chloride channel Ka	0.019
Gab2	growth factor receptor bound protein 2-associated protein 2	0.019
Slc25a48	solute carrier family 25, member 48	0.019
Kiss1r	KISS1 receptor	0.019
Dhh	desert hedgehog	0.019	Mouse
Tcf15	transcription factor 15	0.019
Foxd2	forkhead box D2	0.019
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.019
Figla	folliculogenesis specific basic helix-loop-helix	0.019
Hoxd8	homeobox D8	0.019
Sox7	SRY-box containing gene 7	0.018	Mouse
Hoxa7	homeobox A7	0.018
Drd2	dopamine receptor D2	0.018
Grem1	gremlin 1	0.018
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.018
Prrx2	paired related homeobox 2	0.018
Tulp2	tubby-like protein 2	0.018
Lmx1a	LIM homeobox transcription factor 1 alpha	0.018
Edn3	endothelin 3	0.018
Wnt4	wingless-related MMTV integration site 4	0.018	Mouse
Cldn6	claudin 6	0.018
Klf5	Kruppel-like factor 5	0.018
Fzd9	frizzled homolog 9 (Drosophila)	0.018
Jun	Jun oncogene	0.017
Fgfbp1	fibroblast growth factor binding protein 1	0.017
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.017	Worm
Hoxb9	homeobox B9	0.017
Ngf	nerve growth factor	0.017
Sall3	sal-like 3 (Drosophila)	0.017	Fly
Fzd4	frizzled homolog 4 (Drosophila)	0.017
Foxf1a	forkhead box F1a	0.017
Mapk12	mitogen-activated protein kinase 12	0.017
Alx3	aristaless-like homeobox 3	0.017
Bmp2	bone morphogenetic protein 2	0.017
Gas1	growth arrest specific 1	0.017
Fzd6	frizzled homolog 6 (Drosophila)	0.017
Hoxc4	homeobox C4	0.017
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.016
Nppc	natriuretic peptide type C	0.016
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.016
Clic3	chloride intracellular channel 3	0.016
Tbx1	T-box 1	0.016
Gdf6	growth differentiation factor 6	0.016	Mouse
Fgf2	fibroblast growth factor 2	0.016	Mouse
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.016
Atoh7	atonal homolog 7 (Drosophila)	0.016
Wnt5a	wingless-related MMTV integration site 5A	0.016	Mouse
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.016
Axin2	axin2	0.016
Itga3	integrin alpha 3	0.015
BC024139	cDNA sequence BC024139	0.015
Olig2	oligodendrocyte transcription factor 2	0.015
Gdf1	growth differentiation factor 1	0.015
Adrb1	adrenergic receptor, beta 1	0.015
Gsc	goosecoid homeobox	0.015
Chrdl2	chordin-like 2	0.015
Adam17	a disintegrin and metallopeptidase domain 17	0.015
Cilp2	cartilage intermediate layer protein 2	0.015
Col4a4	collagen, type IV, alpha 4	0.015
Neurog3	neurogenin 3	0.015
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.015	Mouse
Dlx4	distal-less homeobox 4	0.014
Hhex	hematopoietically expressed homeobox	0.014
Vipr1	vasoactive intestinal peptide receptor 1	0.014
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.014
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.014
Glra1	glycine receptor, alpha 1 subunit	0.014
Ivl	involucrin	0.014
Krt15	keratin 15	0.014
Myh11	myosin, heavy polypeptide 11, smooth muscle	0.014
Bdnf	brain derived neurotrophic factor	0.014
Vstm2b	V-set and transmembrane domain containing 2B	0.014
Duox2	dual oxidase 2	0.014
Tdgf1	teratocarcinoma-derived growth factor 1	0.014
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.014
Mmp17	matrix metallopeptidase 17	0.013
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.013
Pkdcc	protein kinase domain containing, cytoplasmic	0.013
Sim2	single-minded homolog 2 (Drosophila)	0.013
Vhl	von Hippel-Lindau tumor suppressor	0.013
Otp	orthopedia homolog (Drosophila)	0.013
Arx	aristaless related homeobox	0.013
Fzd1	frizzled homolog 1 (Drosophila)	0.013
Tcam1	testicular cell adhesion molecule 1	0.013
Grhl2	grainyhead-like 2 (Drosophila)	0.013
Fosb	FBJ osteosarcoma oncogene B	0.013
Lmod1	leiomodin 1 (smooth muscle)	0.013
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.013
Zfp42	zinc finger protein 42	0.013
Gja5	gap junction protein, alpha 5	0.013
Adra1b	adrenergic receptor, alpha 1b	0.013
Cabp2	calcium binding protein 2	0.013
Odz2	odd Oz/ten-m homolog 2 (Drosophila)	0.013
Tcte2	t-complex-associated testis expressed 2	0.013
Fgf17	fibroblast growth factor 17	0.013	Mouse
Otx1	orthodenticle homolog 1 (Drosophila)	0.013
Runx2	runt related transcription factor 2	0.013
Nav1	neuron navigator 1	0.012
Crhr2	corticotropin releasing hormone receptor 2	0.012
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.012
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.012
Nobox	NOBOX oogenesis homeobox	0.012
Hist1h1t	histone cluster 1, H1t	0.012
Irx1	Iroquois related homeobox 1 (Drosophila)	0.012
Chrd	chordin	0.012
Hoxd3	homeobox D3	0.012
Hoxa5	homeobox A5	0.012
Crlf1	cytokine receptor-like factor 1	0.012
Rgnef	Rho-guanine nucleotide exchange factor	0.012
Notch2	Notch gene homolog 2 (Drosophila)	0.012	Fly
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.012
Pgr	progesterone receptor	0.012
Col1a1	collagen, type I, alpha 1	0.012
Omp	olfactory marker protein	0.012
Krt72-ps	keratin 72, pseudogene	0.012
Fmn1	formin 1	0.012
Socs5	suppressor of cytokine signaling 5	0.012
Fscn3	fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)	0.012
Bmp8b	bone morphogenetic protein 8b	0.012	Mouse
Foxd1	forkhead box D1	0.011
Tll2	tolloid-like 2	0.011
Sost	sclerostin	0.011
Fgfrl1	fibroblast growth factor receptor-like 1	0.011
Th	tyrosine hydroxylase	0.011
Tmem204	transmembrane protein 204	0.011
Sult5a1	sulfotransferase family 5A, member 1	0.011
Gm13290	predicted gene 13290	0.011
Ltbp4	latent transforming growth factor beta binding protein 4	0.011
Zfp503	zinc finger protein 503	0.011
Dnase1l2	deoxyribonuclease 1-like 2	0.011
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.011
Gdf3	growth differentiation factor 3	0.011
Sstr5	somatostatin receptor 5	0.011
Dmc1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.011
Barx2	BarH-like homeobox 2	0.011
Tmem132e	transmembrane protein 132E	0.011
Foxn1	forkhead box N1	0.011
Dlx5	distal-less homeobox 5	0.011
Spry2	sprouty homolog 2 (Drosophila)	0.011
Cldn5	claudin 5	0.011
Ihh	Indian hedgehog	0.011	Mouse
Hmx3	H6 homeobox 3	0.011
Wnt8a	wingless-related MMTV integration site 8A	0.011	Mouse
Asb10	ankyrin repeat and SOCS box-containing 10	0.011
Lhx9	LIM homeobox protein 9	0.011
Ntn1	netrin 1	0.011
Ptk7	PTK7 protein tyrosine kinase 7	0.011	Fly
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.010
Efs	embryonal Fyn-associated substrate	0.010
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.010
Twist1	twist homolog 1 (Drosophila)	0.010
Theg	testicular haploid expressed gene	0.010
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.010
Ugt8a	UDP galactosyltransferase 8A	0.010
Tbx20	T-box 20	0.010
Hic1	hypermethylated in cancer 1	0.010
Fgf23	fibroblast growth factor 23	0.010
Kcnk3	potassium channel, subfamily K, member 3	0.010
Hoxb3	homeobox B3	0.010
Tecta	tectorin alpha	0.010
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.010
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.010
Lyzl4	lysozyme-like 4	0.010
Nrg3	neuregulin 3	0.010
Hoxa2	homeobox A2	0.010
Hmga2	high mobility group AT-hook 2	0.010
H1foo	H1 histone family, member O, oocyte-specific	0.010