IMP

Process View

Mus musculus

10 genes annotated in mouse

Multi-species View

regulation of hypersensitivity

GO:0002883

Any process that modulates the frequency, rate, or extent of hypersensitivity.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of hypersensitivity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of hypersensitivity" (in gray)

Name	Description	Probability	Func Analog Organism
Ikzf1	IKAROS family zinc finger 1	0.989
Ccr2	chemokine (C-C motif) receptor 2	0.769	Mouse
Ptprc	protein tyrosine phosphatase, receptor type, C	0.730
Lyz2	lysozyme 2	0.719
Cd19	CD19 antigen	0.614
Apoe	apolipoprotein E	0.600
Tyrobp	TYRO protein tyrosine kinase binding protein	0.574
Ifngr1	interferon gamma receptor 1	0.560
Ifng	interferon gamma	0.559
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.351
Ccl2	chemokine (C-C motif) ligand 2	0.344
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.325
Il4	interleukin 4	0.255
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.252
Tlr2	toll-like receptor 2	0.234
Ccr6	chemokine (C-C motif) receptor 6	0.213	Mouse
Tnf	tumor necrosis factor	0.210
Selp	selectin, platelet	0.186
Il2rg	interleukin 2 receptor, gamma chain	0.180
Prdm1	PR domain containing 1, with ZNF domain	0.171
Folr2	folate receptor 2 (fetal)	0.170
Cxcr2	chemokine (C-X-C motif) receptor 2	0.167	Mouse
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.165
Pdcd1	programmed cell death 1	0.160
Cd44	CD44 antigen	0.149
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.124
Fas	Fas (TNF receptor superfamily member 6)	0.121
Ccl3	chemokine (C-C motif) ligand 3	0.119
Cxcl13	chemokine (C-X-C motif) ligand 13	0.104
Il27ra	interleukin 27 receptor, alpha	0.104
Xcr1	chemokine (C motif) receptor 1	0.093	Mouse
C3ar1	complement component 3a receptor 1	0.086
Fasl	Fas ligand (TNF superfamily, member 6)	0.071
Tlr4	toll-like receptor 4	0.067
Il15	interleukin 15	0.066
Clec4n	C-type lectin domain family 4, member n	0.066
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.065
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.062
Cd180	CD180 antigen	0.062
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.061
Blk	B lymphoid kinase	0.061
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.058
Wisp2	WNT1 inducible signaling pathway protein 2	0.057
Cd7	CD7 antigen	0.057
Cd28	CD28 antigen	0.054
Foxp3	forkhead box P3	0.053
Gpr132	G protein-coupled receptor 132	0.052
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.052
Tcra	T-cell receptor alpha chain	0.051
Ccr3	chemokine (C-C motif) receptor 3	0.050	Mouse
Lat	linker for activation of T cells	0.049
Cd4	CD4 antigen	0.049
Myd88	myeloid differentiation primary response gene 88	0.049
C1qb	complement component 1, q subcomponent, beta polypeptide	0.049
Ccr1	chemokine (C-C motif) receptor 1	0.048	Mouse
S1pr4	sphingosine-1-phosphate receptor 4	0.044
Icos	inducible T-cell co-stimulator	0.042
Igh	immunoglobulin heavy chain complex	0.041
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.039
Il10	interleukin 10	0.038
Fcgr3	Fc receptor, IgG, low affinity III	0.036
Vpreb3	pre-B lymphocyte gene 3	0.036
Il1b	interleukin 1 beta	0.035
Ccl6	chemokine (C-C motif) ligand 6	0.035
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.033
Itk	IL2-inducible T-cell kinase	0.032
Ccr5	chemokine (C-C motif) receptor 5	0.031	Mouse
Sit1	suppression inducing transmembrane adaptor 1	0.031
Cxcr3	chemokine (C-X-C motif) receptor 3	0.031	Mouse
Bex6	brain expressed gene 6	0.031
Lta	lymphotoxin A	0.031
Il15ra	interleukin 15 receptor, alpha chain	0.031
Cd96	CD96 antigen	0.029
Inpp5d	inositol polyphosphate-5-phosphatase D	0.029
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.029
H2-Ob	histocompatibility 2, O region beta locus	0.028
Cd247	CD247 antigen	0.028	Mouse
Fcrla	Fc receptor-like A	0.027	Mouse
Itgae	integrin alpha E, epithelial-associated	0.027
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.026
Csf1	colony stimulating factor 1 (macrophage)	0.026
Il2rb	interleukin 2 receptor, beta chain	0.026
Fcna	ficolin A	0.025
Ccl9	chemokine (C-C motif) ligand 9	0.025
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.025
Itgal	integrin alpha L	0.025
Sell	selectin, lymphocyte	0.024
Cybb	cytochrome b-245, beta polypeptide	0.024
Tnfrsf17	tumor necrosis factor receptor superfamily, member 17	0.022
Ccl4	chemokine (C-C motif) ligand 4	0.022
Retn	resistin	0.022
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.022
Cd14	CD14 antigen	0.022
Cd40	CD40 antigen	0.022
Il7r	interleukin 7 receptor	0.022
Prg3	proteoglycan 3	0.021
Cd6	CD6 antigen	0.021
Cd86	CD86 antigen	0.021
Ccl12	chemokine (C-C motif) ligand 12	0.021
Efna1	ephrin A1	0.021
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.021
C3	complement component 3	0.020
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.020
Cd5l	CD5 antigen-like	0.020
Gp9	glycoprotein 9 (platelet)	0.019
Il18r1	interleukin 18 receptor 1	0.019
Gzmk	granzyme K	0.019
Ptgir	prostaglandin I receptor (IP)	0.019
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.019
Lyz1	lysozyme 1	0.018
Ncr1	natural cytotoxicity triggering receptor 1	0.018
Ccr7	chemokine (C-C motif) receptor 7	0.017
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.017
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.017
Pabpc2	poly(A) binding protein, cytoplasmic 2	0.017
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.017
Ccl8	chemokine (C-C motif) ligand 8	0.016
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.016
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.016
Prf1	perforin 1 (pore forming protein)	0.016
Spn	sialophorin	0.016
Gcet2	germinal center expressed transcript 2	0.016
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.016
Tcstv3	2-cell-stage, variable group, member 3	0.016
Batf	basic leucine zipper transcription factor, ATF-like	0.015
Akr1c6	aldo-keto reductase family 1, member C6	0.015
Pou2af1	POU domain, class 2, associating factor 1	0.015
Itgax	integrin alpha X	0.015
Traf3ip2	TRAF3 interacting protein 2	0.015
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.015
Ccr8	chemokine (C-C motif) receptor 8	0.015	Mouse
Sh2d2a	SH2 domain protein 2A	0.015
Il1r1	interleukin 1 receptor, type I	0.015
Birc3	baculoviral IAP repeat-containing 3	0.015
Gpr182	G protein-coupled receptor 182	0.014
AF251705	cDNA sequence AF251705	0.014
Aif1	allograft inflammatory factor 1	0.014
Crtam	cytotoxic and regulatory T cell molecule	0.014
Plg	plasminogen	0.014
Tssk1	testis-specific serine kinase 1	0.014
Ccr4	chemokine (C-C motif) receptor 4	0.014	Mouse
Ciita	class II transactivator	0.014
Il12a	interleukin 12a	0.014
Tbxas1	thromboxane A synthase 1, platelet	0.014
Mpo	myeloperoxidase	0.014
Tlr7	toll-like receptor 7	0.014
F9	coagulation factor IX	0.014
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.013
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.013
Il22	interleukin 22	0.013
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.013
Slamf1	signaling lymphocytic activation molecule family member 1	0.013
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.013
Tnip1	TNFAIP3 interacting protein 1	0.013
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.013
Cd22	CD22 antigen	0.013
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.013
Cxcr5	chemokine (C-X-C motif) receptor 5	0.013	Mouse
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.013
Hp	haptoglobin	0.013
Reg2	regenerating islet-derived 2	0.013
Cd2	CD2 antigen	0.013
Mmp9	matrix metallopeptidase 9	0.013
Mrc1	mannose receptor, C type 1	0.013
Slpi	secretory leukocyte peptidase inhibitor	0.013
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.012
Ccr9	chemokine (C-C motif) receptor 9	0.012	Mouse
Cfh	complement component factor h	0.012
Cd3g	CD3 antigen, gamma polypeptide	0.012
Fcgr1	Fc receptor, IgG, high affinity I	0.012
Il18rap	interleukin 18 receptor accessory protein	0.012
Itgb2	integrin beta 2	0.012
Zp2	zona pellucida glycoprotein 2	0.012
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.012
Zan	zonadhesin	0.012
Apoh	apolipoprotein H	0.012
Il12rb2	interleukin 12 receptor, beta 2	0.012
C1qc	complement component 1, q subcomponent, C chain	0.012
Lck	lymphocyte protein tyrosine kinase	0.012
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.012
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.012
Pzp	pregnancy zone protein	0.011	Mouse
Sele	selectin, endothelial cell	0.011
Ctss	cathepsin S	0.011
Hmox1	heme oxygenase (decycling) 1	0.011
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.011
Fmo3	flavin containing monooxygenase 3	0.011
Elane	elastase, neutrophil expressed	0.011
Fpr2	formyl peptide receptor 2	0.011
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.011
Myf6	myogenic factor 6	0.011
Mcpt8	mast cell protease 8	0.011
Pax5	paired box gene 5	0.010
C1ra	complement component 1, r subcomponent A	0.010
Rhoh	ras homolog gene family, member H	0.010
Oosp1	oocyte secreted protein 1	0.010
Prg2	proteoglycan 2, bone marrow	0.010