IMP

Process View

Mus musculus

24 genes annotated in mouse

Multi-species View

negative regulation of cell division

GO:0051782

Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cell division"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of cell division" (in gray)

Name	Description	Probability	Func Analog Organism
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.919
Shh	sonic hedgehog	0.753
Trp53	transformation related protein 53	0.409	Zebrafish
Brca1	breast cancer 1	0.283
Brca2	breast cancer 2	0.216
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.170
Gli2	GLI-Kruppel family member GLI2	0.156
Cdk2	cyclin-dependent kinase 2	0.148
Mdm2	transformed mouse 3T3 cell double minute 2	0.139
Ctnnb1	catenin (cadherin associated protein), beta 1	0.107
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.100
Sox9	SRY-box containing gene 9	0.099
Ptch1	patched homolog 1	0.098
Mdm4	transformed mouse 3T3 cell double minute 4	0.090
Lin9	lin-9 homolog (C. elegans)	0.083
Trim59	tripartite motif-containing 59	0.082
Fgfr2	fibroblast growth factor receptor 2	0.070
Cenpe	centromere protein E	0.069
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.067
Dtl	denticleless homolog (Drosophila)	0.067
Rb1	retinoblastoma 1	0.066
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.066	Human
Cdca8	cell division cycle associated 8	0.064
Ccnb1	cyclin B1	0.063
Fbxo5	F-box protein 5	0.063
Atf4	activating transcription factor 4	0.063
Ncapg2	non-SMC condensin II complex, subunit G2	0.062
Trip13	thyroid hormone receptor interactor 13	0.062
Mis18bp1	MIS18 binding protein 1	0.058
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.052
Rpgrip1l	Rpgrip1-like	0.051
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.050
Cnot1	CCR4-NOT transcription complex, subunit 1	0.049
Cdk1	cyclin-dependent kinase 1	0.049
Nog	noggin	0.047
Sgol2	shugoshin-like 2 (S. pombe)	0.047
Max	Max protein	0.045
Kif2c	kinesin family member 2C	0.045
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.045	Fly
Tsc1	tuberous sclerosis 1	0.044
Spag5	sperm associated antigen 5	0.043
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.043
Trp63	transformation related protein 63	0.042
Plk4	polo-like kinase 4 (Drosophila)	0.039
Dna2	DNA replication helicase 2 homolog (yeast)	0.038
4632434I11Rik	RIKEN cDNA 4632434I11 gene	0.037
Ccnf	cyclin F	0.037
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.036
Lrrk2	leucine-rich repeat kinase 2	0.035
Rara	retinoic acid receptor, alpha	0.035
Ncoa3	nuclear receptor coactivator 3	0.035
Fgfr3	fibroblast growth factor receptor 3	0.034
Cenpj	centromere protein J	0.034
Sgol1	shugoshin-like 1 (S. pombe)	0.033
Gli3	GLI-Kruppel family member GLI3	0.033
Alx1	ALX homeobox 1	0.033
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.032
Mastl	microtubule associated serine/threonine kinase-like	0.032
Mns1	meiosis-specific nuclear structural protein 1	0.031
Nlrp5	NLR family, pyrin domain containing 5	0.030
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.029	Fly
Kif23	kinesin family member 23	0.029
Ccna2	cyclin A2	0.029
Ooep	oocyte expressed protein homolog (dog)	0.029
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.028
Cbx1	chromobox homolog 1 (Drosophila HP1 beta)	0.028
Ncapd3	non-SMC condensin II complex, subunit D3	0.028
Trp73	transformation related protein 73	0.028
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.027	Yeast
Capzb	capping protein (actin filament) muscle Z-line, beta	0.027
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.027
Pthlh	parathyroid hormone-like peptide	0.027
Cenpk	centromere protein K	0.027
Polr1a	polymerase (RNA) I polypeptide A	0.026
Hells	helicase, lymphoid specific	0.026
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.025
Bmp4	bone morphogenetic protein 4	0.025	Human
E2f8	E2F transcription factor 8	0.025
Suv39h2	suppressor of variegation 3-9 homolog 2 (Drosophila)	0.025
Gen1	Gen homolog 1, endonuclease (Drosophila)	0.025	Human
Bmp7	bone morphogenetic protein 7	0.024	Human
Neurog2	neurogenin 2	0.024
Apc	adenomatosis polyposis coli	0.024	Human
Prc1	protein regulator of cytokinesis 1	0.024
Zp3	zona pellucida glycoprotein 3	0.024
Skil	SKI-like	0.024
Ncapg	non-SMC condensin I complex, subunit G	0.023
Msx1	homeobox, msh-like 1	0.023
Lig4	ligase IV, DNA, ATP-dependent	0.023
Blm	Bloom syndrome, RecQ helicase-like	0.022	Human
Kif20a	kinesin family member 20A	0.022
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.022
Recql	RecQ protein-like	0.022
Ccne1	cyclin E1	0.022	Fly
Mcm8	minichromosome maintenance deficient 8 (S. cerevisiae)	0.022
Sufu	suppressor of fused homolog (Drosophila)	0.022
Rad18	RAD18 homolog (S. cerevisiae)	0.022
Foxc1	forkhead box C1	0.021
Msh2	mutS homolog 2 (E. coli)	0.021
Apaf1	apoptotic peptidase activating factor 1	0.020
Kif11	kinesin family member 11	0.020
Smad3	MAD homolog 3 (Drosophila)	0.020
Atad5	ATPase family, AAA domain containing 5	0.020
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.020
Kntc1	kinetochore associated 1	0.020
Hist1h2aa	histone cluster 1, H2aa	0.020
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.020
Gsg2	germ cell-specific gene 2	0.020
Dsn1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.019
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.019
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.019
Fancm	Fanconi anemia, complementation group M	0.019
Raf1	v-raf-leukemia viral oncogene 1	0.019
Erg	avian erythroblastosis virus E-26 (v-ets) oncogene related	0.019
Igbp1	immunoglobulin (CD79A) binding protein 1	0.018
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.018
Depdc1a	DEP domain containing 1a	0.018
Mbd4	methyl-CpG binding domain protein 4	0.018
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.018
Arl6ip6	ADP-ribosylation factor-like 6 interacting protein 6	0.017
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.017
Rbl1	retinoblastoma-like 1 (p107)	0.017
Birc5	baculoviral IAP repeat-containing 5	0.017
Atr	ataxia telangiectasia and Rad3 related	0.016
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.016
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.016
Cops7b	COP9 (constitutive photomorphogenic) homolog, subunit 7b (Arabidopsis thaliana)	0.016
Dbf4	DBF4 homolog (S. cerevisiae)	0.016
Haus6	HAUS augmin-like complex, subunit 6	0.016
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.016
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.016
Hist1h2bm	histone cluster 1, H2bm	0.016
Ect2	ect2 oncogene	0.015
Nasp	nuclear autoantigenic sperm protein (histone-binding)	0.015
Zfp101	zinc finger protein 101	0.015
Prmt3	protein arginine N-methyltransferase 3	0.015
Cenpn	centromere protein N	0.015
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.015
Prrx1	paired related homeobox 1	0.015
Srsf1	serine/arginine-rich splicing factor 1	0.015
Lmnb1	lamin B1	0.015
Zeb1	zinc finger E-box binding homeobox 1	0.014
Col2a1	collagen, type II, alpha 1	0.014
Sass6	spindle assembly 6 homolog (C. elegans)	0.014
Gtse1	G two S phase expressed protein 1	0.014
Runx2	runt related transcription factor 2	0.014
Otx2	orthodenticle homolog 2 (Drosophila)	0.014
Stil	Scl/Tal1 interrupting locus	0.014
Lmna	lamin A	0.014
Pias1	protein inhibitor of activated STAT 1	0.013
Pot1a	protection of telomeres 1A	0.013
Skp2	S-phase kinase-associated protein 2 (p45)	0.013
Ifng	interferon gamma	0.013
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.013
4930579G24Rik	RIKEN cDNA 4930579G24 gene	0.013
Mki67	antigen identified by monoclonal antibody Ki 67	0.013
Rbbp4	retinoblastoma binding protein 4	0.013
Hus1	Hus1 homolog (S. pombe)	0.013
Tfdp1	transcription factor Dp 1	0.013
Pten	phosphatase and tensin homolog	0.013
Kif22	kinesin family member 22	0.013
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.013
Rrm1	ribonucleotide reductase M1	0.013
Exo1	exonuclease 1	0.013
Cenpl	centromere protein L	0.013
6720463M24Rik	RIKEN cDNA 6720463M24 gene	0.013
Ilk	integrin linked kinase	0.013
Bard1	BRCA1 associated RING domain 1	0.012
Ifngr1	interferon gamma receptor 1	0.012
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.012
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.012
Anln	anillin, actin binding protein	0.012
Pola1	polymerase (DNA directed), alpha 1	0.012
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.012
Hes1	hairy and enhancer of split 1 (Drosophila)	0.012
Mphosph9	M-phase phosphoprotein 9	0.012
Neurod1	neurogenic differentiation 1	0.012
Gins1	GINS complex subunit 1 (Psf1 homolog)	0.011
Hmgb1	high mobility group box 1	0.011
Phlda2	pleckstrin homology-like domain, family A, member 2	0.011
Orc1	origin recognition complex, subunit 1	0.011
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.011
Tmpo	thymopoietin	0.011
Bmper	BMP-binding endothelial regulator	0.011
Smad2	MAD homolog 2 (Drosophila)	0.011
Rbmxl2	RNA binding motif protein, X-linked-like 2	0.011
Piwil2	piwi-like homolog 2 (Drosophila)	0.011
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.011
Creb1	cAMP responsive element binding protein 1	0.011
Pla2g10	phospholipase A2, group X	0.011
Tert	telomerase reverse transcriptase	0.011
Hmgb2	high mobility group box 2	0.011
Prr11	proline rich 11	0.011
Braf	Braf transforming gene	0.011
Meox2	mesenchyme homeobox 2	0.011
Mks1	Meckel syndrome, type 1	0.011
Ccnb2	cyclin B2	0.011
Sdccag3	serologically defined colon cancer antigen 3	0.011
Hist2h3c2-ps	histone cluster 2, H3c2, pseudogene	0.011
Huwe1	HECT, UBA and WWE domain containing 1	0.011
Ckap2	cytoskeleton associated protein 2	0.011
Tsc2	tuberous sclerosis 2	0.011
Foxo1	forkhead box O1	0.011
Casc5	cancer susceptibility candidate 5	0.010
Ncapd2	non-SMC condensin I complex, subunit D2	0.010
Pms2	postmeiotic segregation increased 2 (S. cerevisiae)	0.010
Gabpb1	GA repeat binding protein, beta 1	0.010
Mms22l	MMS22-like, DNA repair protein	0.010
Prim2	DNA primase, p58 subunit	0.010
Bcl2l1	BCL2-like 1	0.010
Bmp2	bone morphogenetic protein 2	0.010
Eno1	enolase 1, alpha non-neuron	0.010
Cdkn2aipnl	CDKN2A interacting protein N-terminal like	0.010
Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.010
Cstf2	cleavage stimulation factor, 3' pre-RNA subunit 2	0.010
Rbl2	retinoblastoma-like 2	0.010
Tgif1	TGFB-induced factor homeobox 1	0.010
Smn1	survival motor neuron 1	0.010
Rad51	RAD51 homolog (S. cerevisiae)	0.010