Process View
The modification of histone H3 by addition of a methyl group to lysine at position 4 of the histone.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "histone h3 k4 methylation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Rbbp5 | retinoblastoma binding protein 5 | 0.979 | ||
| Wdr5 | WD repeat domain 5 | 0.926 | ||
| Rnf2 | ring finger protein 2 | 0.923 | ||
| Ash2l | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.882 | Human Worm Fly | |
| Gata1 | GATA binding protein 1 | 0.805 | Mouse | |
| Kdm2b | lysine (K)-specific demethylase 2B | 0.765 | ||
| Dnmt3a | DNA methyltransferase 3A | 0.662 | ||
| Trrap | transformation/transcription domain-associated protein | 0.640 | ||
| Arid4b | AT rich interactive domain 4B (RBP1-like) | 0.576 | Mouse | |
| Zfpm2 | zinc finger protein, multitype 2 | 0.565 | ||
| Crebbp | CREB binding protein | 0.485 | ||
| Mll2 | myeloid/lymphoid or mixed-lineage leukemia 2 | 0.430 | ||
| Mll3 | myeloid/lymphoid or mixed-lineage leukemia 3 | 0.404 | Human Worm Fly | |
| Arid4a | AT rich interactive domain 4A (RBP1-like) | 0.295 | ||
| Tnrc6b | trinucleotide repeat containing 6b | 0.216 | ||
| Brca2 | breast cancer 2 | 0.202 | ||
| Runx1 | runt related transcription factor 1 | 0.196 | ||
| Zfp445 | zinc finger protein 445 | 0.150 | ||
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.144 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.140 | ||
| Mll1 | myeloid/lymphoid or mixed-lineage leukemia 1 | 0.133 | ||
| Brwd1 | bromodomain and WD repeat domain containing 1 | 0.133 | ||
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.129 | ||
| Klf3 | Kruppel-like factor 3 (basic) | 0.119 | ||
| Ttc14 | tetratricopeptide repeat domain 14 | 0.112 | ||
| Atrx | alpha thalassemia/mental retardation syndrome X-linked homolog (human) | 0.105 | ||
| Rictor | RPTOR independent companion of MTOR, complex 2 | 0.102 | ||
| Brd4 | bromodomain containing 4 | 0.099 | ||
| Ubtf | upstream binding transcription factor, RNA polymerase I | 0.086 | ||
| Bptf | bromodomain PHD finger transcription factor | 0.078 | ||
| Parp1 | poly (ADP-ribose) polymerase family, member 1 | 0.076 | ||
| Nipbl | Nipped-B homolog (Drosophila) | 0.076 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.072 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.070 | ||
| D4Wsu53e | DNA segment, Chr 4, Wayne State University 53, expressed | 0.069 | ||
| Sfswap | splicing factor, suppressor of white-apricot homolog (Drosophila) | 0.069 | ||
| Rsf1 | remodeling and spacing factor 1 | 0.067 | ||
| Ncoa2 | nuclear receptor coactivator 2 | 0.067 | ||
| Zfp592 | zinc finger protein 592 | 0.066 | ||
| Dnajc5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.064 | ||
| Ctcf | CCCTC-binding factor | 0.064 | ||
| Sf1 | splicing factor 1 | 0.062 | ||
| Zmynd11 | zinc finger, MYND domain containing 11 | 0.059 | ||
| Kdm1a | lysine (K)-specific demethylase 1A | 0.056 | ||
| Med13l | mediator complex subunit 13-like | 0.055 | ||
| Hells | helicase, lymphoid specific | 0.053 | ||
| Gfi1b | growth factor independent 1B | 0.052 | ||
| Ilf3 | interleukin enhancer binding factor 3 | 0.052 | ||
| Rbm5 | RNA binding motif protein 5 | 0.050 | ||
| Pax2 | paired box gene 2 | 0.050 | ||
| Foxp1 | forkhead box P1 | 0.050 | ||
| Myb | myeloblastosis oncogene | 0.050 | Human | |
| Rqcd1 | rcd1 (required for cell differentiation) homolog 1 (S. pombe) | 0.049 | ||
| Chd2 | chromodomain helicase DNA binding protein 2 | 0.045 | ||
| Ncor1 | nuclear receptor co-repressor 1 | 0.044 | ||
| Akt1 | thymoma viral proto-oncogene 1 | 0.044 | ||
| Men1 | multiple endocrine neoplasia 1 | 0.042 | ||
| 4921513D23Rik | RIKEN cDNA 4921513D23 gene | 0.041 | ||
| Ddx46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.040 | ||
| 1700081L11Rik | RIKEN cDNA 1700081L11 gene | 0.040 | ||
| Ncapd3 | non-SMC condensin II complex, subunit D3 | 0.039 | ||
| 2810046L04Rik | RIKEN cDNA 2810046L04 gene | 0.038 | ||
| Zbtb20 | zinc finger and BTB domain containing 20 | 0.038 | ||
| Usp37 | ubiquitin specific peptidase 37 | 0.037 | ||
| Tbx20 | T-box 20 | 0.036 | ||
| Paxip1 | PAX interacting (with transcription-activation domain) protein 1 | 0.036 | ||
| Wbp7 | WW domain binding protein 7 | 0.036 | ||
| Macf1 | microtubule-actin crosslinking factor 1 | 0.035 | ||
| Prr3 | proline-rich polypeptide 3 | 0.035 | ||
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.035 | ||
| Cdk9 | cyclin-dependent kinase 9 (CDC2-related kinase) | 0.035 | Yeast | |
| Zkscan3 | zinc finger with KRAB and SCAN domains 3 | 0.034 | ||
| Phf21a | PHD finger protein 21A | 0.034 | ||
| Setd1b | SET domain containing 1B | 0.034 | ||
| Tnrc6c | trinucleotide repeat containing 6C | 0.033 | ||
| Cbx2 | chromobox homolog 2 (Drosophila Pc class) | 0.031 | ||
| Zfp871 | zinc finger protein 871 | 0.031 | ||
| Ssbp2 | single-stranded DNA binding protein 2 | 0.031 | ||
| Nfat5 | nuclear factor of activated T-cells 5 | 0.030 | ||
| Nbn | nibrin | 0.030 | ||
| Ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.030 | ||
| Hira | histone cell cycle regulation defective homolog A (S. cerevisiae) | 0.029 | ||
| Ankrd16 | ankyrin repeat domain 16 | 0.029 | ||
| Bcor | BCL6 interacting corepressor | 0.029 | Human | |
| Taf4a | TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor | 0.028 | ||
| Hexim1 | hexamethylene bis-acetamide inducible 1 | 0.028 | ||
| Leo1 | Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.028 | ||
| Foxf1a | forkhead box F1a | 0.028 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.028 | ||
| Ino80d | INO80 complex subunit D | 0.028 | ||
| Casc3 | cancer susceptibility candidate 3 | 0.027 | ||
| Paf1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.027 | ||
| Ppara | peroxisome proliferator activated receptor alpha | 0.027 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.026 | ||
| Pold3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.026 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.026 | ||
| Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.025 | ||
| Baz2b | bromodomain adjacent to zinc finger domain, 2B | 0.024 | ||
| Clk1 | CDC-like kinase 1 | 0.024 | ||
| Nup85 | nucleoporin 85 | 0.024 | ||
| Hdac2 | histone deacetylase 2 | 0.024 | ||
| Ncoa6 | nuclear receptor coactivator 6 | 0.023 | ||
| Trim28 | tripartite motif-containing 28 | 0.023 | ||
| Kat2a | K(lysine) acetyltransferase 2A | 0.022 | ||
| Jag1 | jagged 1 | 0.022 | ||
| Plac1 | placental specific protein 1 | 0.022 | ||
| Pknox1 | Pbx/knotted 1 homeobox | 0.022 | ||
| Ddx20 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 0.022 | ||
| Ash1l | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.021 | ||
| Rfwd3 | ring finger and WD repeat domain 3 | 0.021 | ||
| Rcor2 | REST corepressor 2 | 0.021 | ||
| Sfrs18 | serine/arginine-rich splicing factor 18 | 0.021 | ||
| Srrm1 | serine/arginine repetitive matrix 1 | 0.021 | ||
| Smpd4 | sphingomyelin phosphodiesterase 4 | 0.021 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.021 | ||
| Zzef1 | zinc finger, ZZ-type with EF hand domain 1 | 0.021 | ||
| Phrf1 | PHD and ring finger domains 1 | 0.021 | ||
| Srsf4 | serine/arginine-rich splicing factor 4 | 0.020 | ||
| Morc2a | microrchidia 2A | 0.020 | ||
| Lrwd1 | leucine-rich repeats and WD repeat domain containing 1 | 0.020 | ||
| Kdm5a | lysine (K)-specific demethylase 5A | 0.020 | ||
| Rere | arginine glutamic acid dipeptide (RE) repeats | 0.020 | ||
| Mga | MAX gene associated | 0.020 | ||
| Zfp598 | zinc finger protein 598 | 0.020 | ||
| Cbx8 | chromobox homolog 8 (Drosophila Pc class) | 0.019 | ||
| Rfx7 | regulatory factor X, 7 | 0.019 | ||
| Jarid2 | jumonji, AT rich interactive domain 2 | 0.019 | ||
| Rnf44 | ring finger protein 44 | 0.019 | ||
| Phf20 | PHD finger protein 20 | 0.019 | ||
| Kcnj5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.018 | ||
| Prrc2c | proline-rich coiled-coil 2C | 0.018 | ||
| Clk2 | CDC-like kinase 2 | 0.018 | ||
| Smg1 | SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) | 0.018 | ||
| Pom121 | nuclear pore membrane protein 121 | 0.018 | ||
| Pitpnb | phosphatidylinositol transfer protein, beta | 0.018 | ||
| Dhx8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 0.018 | ||
| Klhl24 | kelch-like 24 (Drosophila) | 0.018 | ||
| Gpatch8 | G patch domain containing 8 | 0.018 | ||
| Gata6 | GATA binding protein 6 | 0.017 | Mouse | |
| Braf | Braf transforming gene | 0.017 | ||
| Pcnxl3 | pecanex-like 3 (Drosophila) | 0.017 | ||
| Ehmt1 | euchromatic histone methyltransferase 1 | 0.017 | ||
| Mycbp2 | MYC binding protein 2 | 0.017 | ||
| Ehmt2 | euchromatic histone lysine N-methyltransferase 2 | 0.017 | ||
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.017 | ||
| Mesp1 | mesoderm posterior 1 | 0.017 | ||
| Tmem200b | transmembrane protein 200B | 0.017 | ||
| Myf5 | myogenic factor 5 | 0.017 | ||
| Epor | erythropoietin receptor | 0.017 | ||
| Rbm14 | RNA binding motif protein 14 | 0.017 | ||
| Zfp398 | zinc finger protein 398 | 0.017 | ||
| Brpf1 | bromodomain and PHD finger containing, 1 | 0.016 | ||
| Xpo6 | exportin 6 | 0.016 | ||
| Fam168b | family with sequence similarity 168, member B | 0.016 | ||
| Srpk1 | serine/arginine-rich protein specific kinase 1 | 0.016 | ||
| Smc3 | structural maintenace of chromosomes 3 | 0.016 | ||
| Isg20l2 | interferon stimulated exonuclease gene 20-like 2 | 0.016 | ||
| Orc6 | origin recognition complex, subunit 6 | 0.016 | ||
| Rybp | RING1 and YY1 binding protein | 0.016 | ||
| Prrc2b | proline-rich coiled-coil 2B | 0.016 | ||
| Itsn2 | intersectin 2 | 0.016 | ||
| Nfe2 | nuclear factor, erythroid derived 2 | 0.016 | ||
| Apc | adenomatosis polyposis coli | 0.016 | ||
| Pabpn1 | poly(A) binding protein, nuclear 1 | 0.016 | ||
| Herc1 | hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1 | 0.016 | ||
| Dgcr8 | DiGeorge syndrome critical region gene 8 | 0.016 | ||
| Spnb2 | spectrin beta 2 | 0.015 | ||
| Mecp2 | methyl CpG binding protein 2 | 0.015 | ||
| Hoxa1 | homeobox A1 | 0.015 | ||
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.015 | ||
| Yeats2 | YEATS domain containing 2 | 0.015 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.015 | ||
| Tbx5 | T-box 5 | 0.015 | ||
| Setdb1 | SET domain, bifurcated 1 | 0.015 | ||
| P2rx1 | purinergic receptor P2X, ligand-gated ion channel, 1 | 0.015 | ||
| L3mbtl2 | l(3)mbt-like 2 (Drosophila) | 0.015 | ||
| Ldb1 | LIM domain binding 1 | 0.015 | ||
| Zmym2 | zinc finger, MYM-type 2 | 0.015 | ||
| Zfpm1 | zinc finger protein, multitype 1 | 0.015 | ||
| Suv39h1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.015 | ||
| Smc1a | structural maintenance of chromosomes 1A | 0.014 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.014 | ||
| Ankrd12 | ankyrin repeat domain 12 | 0.014 | ||
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.014 | ||
| Rbm22 | RNA binding motif protein 22 | 0.014 | ||
| Ctr9 | Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.014 | ||
| Muc13 | mucin 13, epithelial transmembrane | 0.014 | ||
| Ncoa5 | nuclear receptor coactivator 5 | 0.014 | ||
| Lats1 | large tumor suppressor | 0.014 | ||
| Prpf3 | PRP3 pre-mRNA processing factor 3 homolog (yeast) | 0.014 | ||
| Kiss1 | KiSS-1 metastasis-suppressor | 0.014 | ||
| Fam48a | family with sequence similarity 48, member A | 0.014 | ||
| Rab23 | RAB23, member RAS oncogene family | 0.014 | ||
| Pafah1b2 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 | 0.014 | ||
| Mcmbp | MCM (minichromosome maintenance deficient) binding protein | 0.014 | ||
| Zfp292 | zinc finger protein 292 | 0.014 | ||
| Tbx3 | T-box 3 | 0.014 | ||
| Man1a2 | mannosidase, alpha, class 1A, member 2 | 0.013 | ||
| Srsf2 | serine/arginine-rich splicing factor 2 | 0.013 | ||
| Polr2a | polymerase (RNA) II (DNA directed) polypeptide A | 0.013 | ||
| Gata5 | GATA binding protein 5 | 0.013 | Mouse | |
| Tmprss2 | transmembrane protease, serine 2 | 0.013 | ||
| Zfp236 | zinc finger protein 236 | 0.013 | ||
| Hmg20a | high mobility group 20A | 0.013 | ||
| Dcaf7 | DDB1 and CUL4 associated factor 7 | 0.013 | ||
| Fbrs | fibrosin | 0.013 | ||
| Ermap | erythroblast membrane-associated protein | 0.013 | ||
| Ep300 | E1A binding protein p300 | 0.013 | ||
| Nolc1 | nucleolar and coiled-body phosphoprotein 1 | 0.013 | ||
| Mbd6 | methyl-CpG binding domain protein 6 | 0.013 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.013 | ||
| Atad5 | ATPase family, AAA domain containing 5 | 0.013 | ||
| Ckap5 | cytoskeleton associated protein 5 | 0.013 | ||
| Ctdp1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | 0.013 | ||
| Cramp1l | Crm, cramped-like (Drosophila) | 0.013 | ||
| Jak2 | Janus kinase 2 | 0.013 | ||
| Hnrnpa0 | heterogeneous nuclear ribonucleoprotein A0 | 0.012 | ||
| Aqr | aquarius | 0.012 | ||
| Med14 | mediator complex subunit 14 | 0.012 | ||
| Usp7 | ubiquitin specific peptidase 7 | 0.012 | ||
| Pum1 | pumilio 1 (Drosophila) | 0.012 | ||
| Mcm4 | minichromosome maintenance deficient 4 homolog (S. cerevisiae) | 0.012 | ||
| Blm | Bloom syndrome, RecQ helicase-like | 0.012 | ||
| Rnf168 | ring finger protein 168 | 0.012 | ||
| Senp7 | SUMO1/sentrin specific peptidase 7 | 0.012 | ||
| Cpsf7 | cleavage and polyadenylation specific factor 7 | 0.012 | ||
| Nvl | nuclear VCP-like | 0.012 | ||
| Rxra | retinoid X receptor alpha | 0.012 | ||
| Hba-x | hemoglobin X, alpha-like embryonic chain in Hba complex | 0.012 | ||
| Atxn7 | ataxin 7 | 0.012 | ||
| She | src homology 2 domain-containing transforming protein E | 0.012 | ||
| Cbx3 | chromobox homolog 3 (Drosophila HP1 gamma) | 0.012 | ||
| Zbtb16 | zinc finger and BTB domain containing 16 | 0.012 | ||
| Brd8 | bromodomain containing 8 | 0.012 | ||
| Rbbp4 | retinoblastoma binding protein 4 | 0.012 | ||
| Hic2 | hypermethylated in cancer 2 | 0.012 | ||
| Xpo5 | exportin 5 | 0.012 | ||
| Helz | helicase with zinc finger domain | 0.012 | ||
| Gclc | glutamate-cysteine ligase, catalytic subunit | 0.012 | ||
| Spen | SPEN homolog, transcriptional regulator (Drosophila) | 0.012 | ||
| Dnmt3l | DNA (cytosine-5-)-methyltransferase 3-like | 0.012 | ||
| Traf7 | TNF receptor-associated factor 7 | 0.011 | ||
| 9030409G11Rik | RIKEN cDNA 9030409G11 gene | 0.011 | ||
| E2f3 | E2F transcription factor 3 | 0.011 | ||
| Rapgef6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.011 | ||
| Prmt3 | protein arginine N-methyltransferase 3 | 0.011 | ||
| Slc38a5 | solute carrier family 38, member 5 | 0.011 | ||
| Slc6a4 | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 0.011 | ||
| Blmh | bleomycin hydrolase | 0.011 | ||
| Abl2 | v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) | 0.011 | ||
| Nfya | nuclear transcription factor-Y alpha | 0.011 | ||
| Zmynd8 | zinc finger, MYND-type containing 8 | 0.011 | ||
| Bap1 | Brca1 associated protein 1 | 0.011 | ||
| Hemgn | hemogen | 0.011 | ||
| Stc2 | stanniocalcin 2 | 0.011 | ||
| Tbc1d23 | TBC1 domain family, member 23 | 0.011 | ||
| Zbtb46 | zinc finger and BTB domain containing 46 | 0.011 | ||
| Atp2b1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.011 | ||
| Sap130 | Sin3A associated protein | 0.011 | ||
| Csrp2bp | cysteine and glycine-rich protein 2 binding protein | 0.011 | ||
| Efnb2 | ephrin B2 | 0.011 | ||
| Polm | polymerase (DNA directed), mu | 0.011 | ||
| Tspyl1 | testis-specific protein, Y-encoded-like 1 | 0.011 | ||
| Nck2 | non-catalytic region of tyrosine kinase adaptor protein 2 | 0.011 | ||
| Ccnt2 | cyclin T2 | 0.011 | ||
| Taok1 | TAO kinase 1 | 0.010 | ||
| Cpsf4 | cleavage and polyadenylation specific factor 4 | 0.010 | ||
| Sp4 | trans-acting transcription factor 4 | 0.010 | ||
| Hcfc1 | host cell factor C1 | 0.010 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.010 | ||
| Cdan1 | congenital dyserythropoietic anemia, type I (human) | 0.010 | ||
| Eml4 | echinoderm microtubule associated protein like 4 | 0.010 | ||
| Hoxa4 | homeobox A4 | 0.010 | ||
| Zfp60 | zinc finger protein 60 | 0.010 | ||
| Adam19 | a disintegrin and metallopeptidase domain 19 (meltrin beta) | 0.010 | ||
| Gypa | glycophorin A | 0.010 | ||
| Rnps1 | ribonucleic acid binding protein S1 | 0.010 | ||
| 2410002F23Rik | RIKEN cDNA 2410002F23 gene | 0.010 | ||
| Taf5l | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor | 0.010 | ||
| Alms1 | Alstrom syndrome 1 homolog (human) | 0.010 | ||
| Rfx3 | regulatory factor X, 3 (influences HLA class II expression) | 0.010 | ||
| Ski | ski sarcoma viral oncogene homolog (avian) | 0.010 | ||
| Hoxb4 | homeobox B4 | 0.010 | ||
| Ewsr1 | Ewing sarcoma breakpoint region 1 | 0.010 | ||
| Top2b | topoisomerase (DNA) II beta | 0.010 |