IMP
Process View
negative regulation of endothelial cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of endothelial cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Acvr1 | activin A receptor, type 1 | 0.942 | Mouse | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.901 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.829 | ||
| Apc | adenomatosis polyposis coli | 0.792 | ||
| Psen1 | presenilin 1 | 0.786 | ||
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.784 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.621 | ||
| Vegfa | vascular endothelial growth factor A | 0.610 | ||
| Jag1 | jagged 1 | 0.610 | ||
| Foxc1 | forkhead box C1 | 0.603 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.537 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.530 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.509 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.477 | Mouse | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.453 | Mouse | |
| Atp7a | ATPase, Cu++ transporting, alpha polypeptide | 0.440 | ||
| Pten | phosphatase and tensin homolog | 0.439 | ||
| Eng | endoglin | 0.435 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.407 | ||
| Bptf | bromodomain PHD finger transcription factor | 0.384 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.366 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.353 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.345 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.327 | Mouse | |
| Hic1 | hypermethylated in cancer 1 | 0.326 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.302 | ||
| Prrx1 | paired related homeobox 1 | 0.238 | ||
| Sox9 | SRY-box containing gene 9 | 0.203 | ||
| Aplnr | apelin receptor | 0.203 | ||
| Ednra | endothelin receptor type A | 0.202 | ||
| Tgfbr3 | transforming growth factor, beta receptor III | 0.188 | ||
| Rxra | retinoid X receptor alpha | 0.172 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.170 | Mouse | |
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.170 | ||
| Braf | Braf transforming gene | 0.149 | ||
| Cdh5 | cadherin 5 | 0.144 | ||
| Tgfbr1 | transforming growth factor, beta receptor I | 0.136 | Mouse Rat | |
| Lox | lysyl oxidase | 0.115 | ||
| Ece1 | endothelin converting enzyme 1 | 0.110 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.109 | ||
| Fgf8 | fibroblast growth factor 8 | 0.104 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.103 | ||
| Xiap | X-linked inhibitor of apoptosis | 0.100 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.097 | ||
| Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.094 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.093 | ||
| Efnb2 | ephrin B2 | 0.089 | ||
| Ptch1 | patched homolog 1 | 0.089 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.085 | ||
| S1pr2 | sphingosine-1-phosphate receptor 2 | 0.084 | ||
| Psen2 | presenilin 2 | 0.083 | ||
| Espn | espin | 0.083 | ||
| Mrc2 | mannose receptor, C type 2 | 0.081 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.080 | ||
| Gpc3 | glypican 3 | 0.079 | ||
| Rara | retinoic acid receptor, alpha | 0.076 | ||
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.070 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.070 | ||
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.067 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.063 | ||
| Pdgfb | platelet derived growth factor, B polypeptide | 0.060 | ||
| Rarg | retinoic acid receptor, gamma | 0.058 | ||
| Erbb2ip | Erbb2 interacting protein | 0.054 | ||
| Zmym5 | zinc finger, MYM-type 5 | 0.052 | ||
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.050 | ||
| Smo | smoothened homolog (Drosophila) | 0.049 | ||
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.048 | ||
| Ush1c | Usher syndrome 1C homolog (human) | 0.048 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.047 | ||
| Kit | kit oncogene | 0.046 | ||
| Nf1 | neurofibromatosis 1 | 0.046 | ||
| Smad5 | MAD homolog 5 (Drosophila) | 0.045 | ||
| Hipk3 | homeodomain interacting protein kinase 3 | 0.045 | ||
| Kif3a | kinesin family member 3A | 0.044 | ||
| Hoxa1 | homeobox A1 | 0.044 | ||
| Shc1 | src homology 2 domain-containing transforming protein C1 | 0.044 | ||
| Prkg1 | protein kinase, cGMP-dependent, type I | 0.044 | ||
| Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.042 | Mouse | |
| Pax3 | paired box gene 3 | 0.042 | ||
| Aff4 | AF4/FMR2 family, member 4 | 0.041 | ||
| Tbx1 | T-box 1 | 0.039 | ||
| Fshr | follicle stimulating hormone receptor | 0.039 | ||
| Pkd1 | polycystic kidney disease 1 homolog | 0.039 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.037 | ||
| Chrd | chordin | 0.037 | ||
| Ednrb | endothelin receptor type B | 0.036 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.036 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.036 | ||
| Mll1 | myeloid/lymphoid or mixed-lineage leukemia 1 | 0.035 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.034 | ||
| Pik3c2a | phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide | 0.034 | ||
| Dll4 | delta-like 4 (Drosophila) | 0.034 | ||
| Atp2b2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.033 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.033 | ||
| Efnb1 | ephrin B1 | 0.032 | ||
| Gnrh1 | gonadotropin releasing hormone 1 | 0.032 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.032 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.032 | ||
| Cpd | carboxypeptidase D | 0.032 | ||
| Egfl7 | EGF-like domain 7 | 0.031 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.029 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.029 | ||
| Ids | iduronate 2-sulfatase | 0.028 | ||
| Kiss1r | KISS1 receptor | 0.028 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.028 | ||
| Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.028 | ||
| Plxna1 | plexin A1 | 0.027 | ||
| Fzd4 | frizzled homolog 4 (Drosophila) | 0.027 | ||
| Foxg1 | forkhead box G1 | 0.027 | ||
| Gja1 | gap junction protein, alpha 1 | 0.027 | ||
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.026 | ||
| Efemp2 | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | 0.026 | ||
| Fbn1 | fibrillin 1 | 0.026 | ||
| Grb10 | growth factor receptor bound protein 10 | 0.026 | ||
| Epha3 | Eph receptor A3 | 0.026 | ||
| Rarb | retinoic acid receptor, beta | 0.026 | ||
| Prrx2 | paired related homeobox 2 | 0.024 | ||
| Rb1 | retinoblastoma 1 | 0.024 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.024 | ||
| Creb1 | cAMP responsive element binding protein 1 | 0.023 | ||
| Stk3 | serine/threonine kinase 3 (Ste20, yeast homolog) | 0.023 | ||
| Sema6d | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.022 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.022 | ||
| Sgpl1 | sphingosine phosphate lyase 1 | 0.022 | ||
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.021 | ||
| Ar | androgen receptor | 0.021 | ||
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.020 | ||
| Akt3 | thymoma viral proto-oncogene 3 | 0.020 | ||
| Itch | itchy, E3 ubiquitin protein ligase | 0.020 | ||
| Cachd1 | cache domain containing 1 | 0.020 | ||
| Plcb1 | phospholipase C, beta 1 | 0.020 | ||
| Ebf3 | early B-cell factor 3 | 0.020 | ||
| Angpt1 | angiopoietin 1 | 0.020 | ||
| Vcl | vinculin | 0.019 | ||
| Itgav | integrin alpha V | 0.019 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.019 | ||
| Foxc2 | forkhead box C2 | 0.019 | ||
| Cacna2d1 | calcium channel, voltage-dependent, alpha2/delta subunit 1 | 0.019 | ||
| Meox2 | mesenchyme homeobox 2 | 0.018 | ||
| Bmp5 | bone morphogenetic protein 5 | 0.018 | ||
| Ddr2 | discoidin domain receptor family, member 2 | 0.018 | ||
| Yap1 | yes-associated protein 1 | 0.018 | ||
| Kiss1 | KiSS-1 metastasis-suppressor | 0.018 | ||
| Ptprg | protein tyrosine phosphatase, receptor type, G | 0.018 | ||
| Ptf1a | pancreas specific transcription factor, 1a | 0.018 | ||
| Hoxa3 | homeobox A3 | 0.017 | ||
| Egfr | epidermal growth factor receptor | 0.017 | ||
| She | src homology 2 domain-containing transforming protein E | 0.017 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.017 | ||
| Itga8 | integrin alpha 8 | 0.017 | ||
| Trove2 | TROVE domain family, member 2 | 0.017 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.016 | ||
| Kif1b | kinesin family member 1B | 0.016 | ||
| Fmnl3 | formin-like 3 | 0.016 | ||
| Socs5 | suppressor of cytokine signaling 5 | 0.016 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.016 | ||
| Timp2 | tissue inhibitor of metalloproteinase 2 | 0.016 | ||
| Pgr | progesterone receptor | 0.016 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.016 | ||
| Shh | sonic hedgehog | 0.015 | ||
| Emp2 | epithelial membrane protein 2 | 0.015 | ||
| Idua | iduronidase, alpha-L- | 0.015 | ||
| Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.015 | ||
| Ldlr | low density lipoprotein receptor | 0.015 | ||
| Rgs5 | regulator of G-protein signaling 5 | 0.015 | ||
| Jag2 | jagged 2 | 0.015 | ||
| Mef2a | myocyte enhancer factor 2A | 0.015 | ||
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.015 | ||
| Efs | embryonal Fyn-associated substrate | 0.015 | ||
| Nfia | nuclear factor I/A | 0.015 | ||
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.015 | ||
| Inhbb | inhibin beta-B | 0.015 | ||
| Mkl2 | MKL/myocardin-like 2 | 0.015 | ||
| Kcne1 | potassium voltage-gated channel, Isk-related subfamily, member 1 | 0.014 | ||
| Fzd7 | frizzled homolog 7 (Drosophila) | 0.014 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.014 | ||
| Ror1 | receptor tyrosine kinase-like orphan receptor 1 | 0.014 | ||
| Ush1g | Usher syndrome 1G homolog (human) | 0.014 | ||
| Grxcr1 | glutaredoxin, cysteine rich 1 | 0.014 | ||
| Sdc3 | syndecan 3 | 0.014 | ||
| Kitl | kit ligand | 0.014 | ||
| Sema3a | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.014 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.014 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.014 | ||
| Col12a1 | collagen, type XII, alpha 1 | 0.014 | ||
| Gata3 | GATA binding protein 3 | 0.014 | ||
| Mib1 | mindbomb homolog 1 (Drosophila) | 0.013 | ||
| Spred1 | sprouty protein with EVH-1 domain 1, related sequence | 0.013 | ||
| Trp53 | transformation related protein 53 | 0.013 | ||
| Cdh11 | cadherin 11 | 0.013 | ||
| Smad7 | MAD homolog 7 (Drosophila) | 0.013 | ||
| Lama5 | laminin, alpha 5 | 0.013 | ||
| Man1a2 | mannosidase, alpha, class 1A, member 2 | 0.013 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.012 | ||
| Runx1 | runt related transcription factor 1 | 0.012 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.012 | ||
| Fmn1 | formin 1 | 0.012 | ||
| Cacna1c | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.012 | ||
| Zfp260 | zinc finger protein 260 | 0.012 | ||
| Inhba | inhibin beta-A | 0.012 | ||
| Hip1 | huntingtin interacting protein 1 | 0.012 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.012 | ||
| Usp25 | ubiquitin specific peptidase 25 | 0.012 | ||
| Nfib | nuclear factor I/B | 0.012 | ||
| Irs1 | insulin receptor substrate 1 | 0.011 | ||
| Mid2 | midline 2 | 0.011 | ||
| Acvrl1 | activin A receptor, type II-like 1 | 0.011 | ||
| Tcf7l2 | transcription factor 7-like 2, T-cell specific, HMG-box | 0.011 | ||
| Mef2c | myocyte enhancer factor 2C | 0.011 | ||
| Smad2 | MAD homolog 2 (Drosophila) | 0.011 | ||
| Gcnt2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme | 0.011 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.011 | ||
| Jmjd1c | jumonji domain containing 1C | 0.011 | ||
| Tpbg | trophoblast glycoprotein | 0.011 | ||
| Il2rg | interleukin 2 receptor, gamma chain | 0.011 | ||
| Rbfox2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.011 | ||
| Acvr2a | activin receptor IIA | 0.011 | ||
| Sema3c | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.011 | ||
| Tgfb3 | transforming growth factor, beta 3 | 0.011 | ||
| Ext1 | exostoses (multiple) 1 | 0.011 | ||
| Skil | SKI-like | 0.011 | ||
| Twsg1 | twisted gastrulation homolog 1 (Drosophila) | 0.010 | ||
| Hdac7 | histone deacetylase 7 | 0.010 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.010 | ||
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.010 | ||
| Homer3 | homer homolog 3 (Drosophila) | 0.010 | ||
| Tbx2 | T-box 2 | 0.010 | ||
| Maf | avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog | 0.010 | ||
| Kdr | kinase insert domain protein receptor | 0.010 | ||
| Malt1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.010 | ||
| Fzd6 | frizzled homolog 6 (Drosophila) | 0.010 |