IMP

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of leukocyte mediated cytotoxicity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of leukocyte mediated cytotoxicity" (in gray)

Name	Description	Probability	Func Analog Organism
zgc:64115	zgc:64115	0.672
syngr1a	synaptogyrin 1a	0.228
hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.141
coro1a	coronin, actin binding protein, 1A	0.109
styk1	serine/threonine/tyrosine kinase 1	0.107
polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.090
zgc:64161	zgc:64161	0.086	Mouse
itln1	intelectin 1	0.084
zgc:174863	zgc:174863	0.077
wasb	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b	0.075
itln3	intelectin 3	0.070
defbl3	defensin, beta-like 3	0.069
trim25	tripartite motif-containing 25	0.067
dmrt1	doublesex and mab-3 related transcription factor 1	0.062
c1qc	complement component 1, q subcomponent, C chain	0.061
col5a3	collagen, type V, alpha 3	0.060
cx34.4	connexin 34.4	0.055
pkz	protein kinase containing Z-DNA binding domains	0.054
vps39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.052
illr1	immune-related, lectin-like receptor 1	0.052	Zebrafish
pcsk2	proprotein convertase subtilisin/kexin type 2	0.050
pcsk1	proprotein convertase subtilisin/kexin type 1	0.049
b2m	beta-2-microglobulin	0.048	Mouse
cul1b	cullin 1b	0.044
gsk3b	glycogen synthase kinase 3 beta	0.043
zgc:101598	zgc:101598	0.042
foxp3a	forkhead box P3a	0.042
tlr22	toll-like receptor 22	0.042
pcsk7	proprotein convertase subtilisin/kexin type 7	0.038
pigu	phosphatidylinositol glycan anchor biosynthesis, class U	0.038
gch2	GTP cyclohydrolase 2	0.038
illr3	immune-related, lectin-like receptor 3	0.036
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.036
psmb9a	proteasome (prosome, macropain) subunit, beta type, 9a	0.036
zgc:63831	zgc:63831	0.034
zgc:162329	zgc:162329	0.033
trpm6	transient receptor potential cation channel, subfamily M, member 6	0.032
cd40lg	CD40 ligand	0.032
nitr8	novel immune-type receptor 8	0.032
mitfa	microphthalmia-associated transcription factor a	0.032
irf11	interferon regulatory factor 11	0.031
ifnphi1	interferon phi 1	0.031
nitr5	novel immune-type receptor 5 and immune-type receptor 5-like	0.031
slc12a10.1	solute carrier family 12 (sodium/potassium/chloride transporters), member 10.1	0.031
tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.030
asah1b	N-acylsphingosine amidohydrolase (acid ceramidase) 1b	0.030
npy7r	neuropeptide Y receptor Y7	0.030
zgc:112072	zgc:112072	0.030
arpc1b	actin related protein 2/3 complex, subunit 1B	0.029
stat1a	signal transduction and activation of transcription 1a	0.029
cxcr3.2	chemokine (C-X-C motif) receptor 3.2	0.029
zgc:64051	zgc:64051	0.028
nitr4a	novel immune-type receptor 4a	0.028
ppp2r5ea	protein phosphatase 2, regulatory subunit B', epsilon isoform a	0.028
lrrc33	leucine rich repeat containing 33	0.028
pcsk9	proprotein convertase subtilisin/kexin type 9	0.028
eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.027
nitr12	novel immune-type receptor 12	0.027
gmfg	glia maturation factor, gamma	0.027
sdcbp	syndecan binding protein (syntenin)	0.027
c3c	complement component c3c	0.027
LOC567441	interferon-induced protein with tetratricopeptide repeats 5-like	0.027
tnfsf18	tumor necrosis factor (ligand) superfamily, member 18	0.027
psme1	proteasome activator subunit 1	0.026
g6pd	glucose-6-phosphate dehydrogenase	0.026
clica	chloride intracellular channel a	0.026
waca	WW domain containing adaptor with coiled-coil a	0.026
gpr22	G protein-coupled receptor 22	0.026
igfbp6a	insulin-like growth factor binding protein 6a	0.026
zgc:112018	zgc:112018	0.025
zgc:162337	zgc:162337	0.025
tec	tec protein tyrosine kinase	0.025
jak3	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	0.025
ugt5c2	UDP glucuronosyltransferase 5 family, polypeptide C2	0.025
ptk6a	PTK6 protein tyrosine kinase 6a	0.025
si:ch211-140f21.1	si:ch211-140f21.1	0.025
c1qb	complement component 1, q subcomponent, B chain	0.025
ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.024
defbl1	defensin, beta-like 1	0.024
c3b	complement component c3b	0.024
tlr21	toll-like receptor 21	0.024
sec31b	Sec31 homolog B (S. cerevisiae)	0.024
dock8	dedicator of cytokinesis 8	0.024
LOC555739	serine/threonine-protein kinase LMTK1-like	0.024
npy4r	neuropeptide Y receptor Y4	0.023
LOC793458	peptide Y-like	0.023
LOC100538108	tissue-type plasminogen activator-like	0.023
nitr9	novel immune-type receptor 9	0.023
tlr9	toll-like receptor 9	0.023
si:ch211-244b2.4	si:ch211-244b2.4	0.023
LOC794786	interferon-induced protein with tetratricopeptide repeats 1-like	0.022
adipor2	adiponectin receptor 2	0.022
sqstm1	sequestosome 1	0.022
cxc46	CXC chemokine 46	0.022
illr4	immune-related, lectin-like receptor 4	0.021	Zebrafish
fgf23	fibroblast growth factor 23	0.021
taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto	0.021
tbx21	T-box 21	0.021
nitr13	novel immune-type receptor 13	0.021
zgc:171538	zgc:171538	0.020
sh3bp5	SH3-domain binding protein 5 (BTK-associated)	0.020
camk2g2	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2	0.020
glra1	glycine receptor, alpha 1	0.020
psma6b	proteasome (prosome, macropain) subunit, alpha type, 6b	0.020
zgc:153917	zgc:153917	0.020
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.020
pyya	peptide YYa	0.020
cd8a	CD8 antigen, alpha polypeptide	0.020
crfa31.2	IL-4RA-like protein 2	0.020
LOC100005283	Gig2-like protein DreE	0.019
zgc:77817	zgc:77817	0.019
atp2b1b	ATPase, Ca++ transporting, plasma membrane 1b	0.019
mst1rb	macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b	0.019
arrdc3a	arrestin domain containing 3a	0.019
plaua	plasminogen activator, urokinase a	0.019
gpr143	G protein-coupled receptor 143	0.019
wnt5a	wingless-type MMTV integration site family, member 5a	0.019
stat6	signal transducer and activator of transcription 6, interleukin-4 induced	0.019
echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.019
cd209	CD209 molecule	0.019	Zebrafish
grna	granulin a	0.019
adrb2a	adrenergic receptor, beta 2a	0.019
spns2	spinster homolog 2 (Drosophila)	0.019
fcer1gl	Fc receptor, IgE, high affinity I, gamma polypeptide like	0.019
ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	0.018
slco2a1	solute carrier organic anion transporter family, member 2A1	0.018
kpna3	karyopherin (importin) alpha 3	0.018
wisp1b	WNT1 inducible signaling pathway protein 1b	0.018
itk	IL2-inducible T-cell kinase	0.018
aox3	aldehyde oxidase 3	0.018
LOC566020	Gig2-like protein DreO	0.018
LOC555163	myelin protein zero-like protein 1-like	0.018
psme2	proteasome activator subunit 2	0.018
zgc:101614	zgc:101614	0.018
zgc:172101	zgc:172101	0.018
fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.018
ptger2b	prostaglandin E receptor 2b (subtype EP2)	0.018
LOC566708	FL cytokine receptor-like	0.017
npsnl	nephrosin-like	0.017
si:dkeyp-22b2.3	si:dkeyp-22b2.3	0.017
il12bb	interleukin 12B, b	0.017	Mouse
acsl3a	acyl-CoA synthetase long-chain family member 3a	0.017
map1lc3a	microtubule-associated protein 1 light chain 3 alpha	0.017
crygm2f	crystallin, gamma M2f	0.017
rbbp6	retinoblastoma binding protein 6	0.017
cd40	CD40 antigen	0.017
cd4-4	cd4-4 protein	0.017
pth1b	parathyroid hormone 1b	0.016
synpo2la	synaptopodin 2-like a	0.016
LOC100000934	hypothetical protein LOC100000934	0.016
tpsn	tapasin	0.016
nos2a	nitric oxide synthase 2a, inducible	0.016
slc22a7a	solute carrier family 22 (organic anion transporter), member 7a	0.016
irak4	interleukin-1 receptor-associated kinase 4	0.016
LOC100005232	Gig2-like protein DreD	0.016
zgc:110602	zgc:110602	0.016
eomesb	eomesodermin homolog b	0.016
zgc:123282	zgc:123282	0.016
stat1b	signal transducer and activator of transcription 1b	0.016
lrtm2	leucine-rich repeats and transmembrane domains 2	0.016
si:ch211-219p7.1	si:ch211-219p7.1	0.016
ccnt2a	cyclin T2a	0.016
cry1a	cryptochrome 1a	0.015
amh	anti-Mullerian hormone	0.015
inppl1a	inositol polyphosphate phosphatase-like 1a	0.015
pank1a	pantothenate kinase 1a	0.015
cps1	carbamoyl-phosphate synthase 1, mitochondrial	0.015
pax7b	paired box gene 7b	0.015
brd9	bromodomain containing 9	0.015
si:dkey-21e7.2	si:dkey-21e7.2	0.015
ugt5a2	UDP glucuronosyltransferase 5 family, polypeptide A2	0.015
lmo7a	LIM domain only 7a	0.015
LOC100534776	toll-like receptor 7-like	0.015
slco1d1	solute carrier organic anion transporter family, member 1D1	0.015
dub	duboraya	0.015
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.015
gbp1	guanylate binding protein 1	0.015
sult1st4	sulfotransferase family 1, cytosolic sulfotransferase 4	0.015
fcho2	FCH domain only 2	0.015
si:dkey-48j7.5	si:dkey-48j7.5	0.015
samsn1a	SAM domain, SH3 domain and nuclear localisation signals, 1a	0.015
irf7	interferon regulatory factor 7	0.014
ros1	v-ros UR2 sarcoma virus oncogene homolog 1 (avian)	0.014
LOC563797	killer cell lectin-like receptor subfamily B member 1A-like	0.014
exoc6	exocyst complex component 6	0.014
LOC567405	novel protein similar to vertebrate megakaryocyte-associated tyrosine kinase (MATK)	0.014
or111-7	odorant receptor, family D, subfamily 111, member 7	0.014
zgc:92511	zgc:92511	0.014
sc:d173	sc:d173	0.014
slc9a1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.014
ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.014
il10	interleukin 10	0.014
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.014
mep1b	meprin A, beta	0.014
mtx1b	metaxin 1b	0.014
fhl2b	four and a half LIM domains 2b	0.014
irf9	interferon regulatory factor 9	0.013
foxq1b	forkhead box Q1b	0.013
lta	lymphotoxin alpha (TNF superfamily, member 1)	0.013
zgc:77906	zgc:77906	0.013
ugt1a7	UDP glucuronosyltransferase 1 family, polypeptide A7	0.013
il22	interleukin 22	0.013
insl5b	insulin-like 5b	0.013
LOC795096	hypothetical protein LOC795096	0.013
LOC100005405	Gig2-like protein DreJ	0.013
si:dkey-220f10.4	si:dkey-220f10.4	0.013
LOC561406	prostacyclin receptor-like	0.013
bactin2	bactin2	0.013
ugt5c1	UDP glucuronosyltransferase 5 family, polypeptide C1	0.013
ctnnd1	catenin (cadherin-associated protein), delta 1	0.013
impdh1b	inosine 5'-phosphate dehydrogenase 1b	0.013
figla	factor in the germline alpha	0.013
cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.013
tnfaip8l2a	tumor necrosis factor, alpha-induced protein 8, like 2a	0.013
tyrobp	TYRO protein tyrosine kinase binding protein	0.013
sparcl1	SPARC-like 1	0.013
ugt2b6	UDP glucuronosyltransferase 2 family, polypeptide B6	0.013
mavs	mitochondrial antiviral signaling protein	0.013
coro6	coronin 6	0.013
rasgrp3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	0.013
LOC100150997	similar to adenosine A1 receptor	0.013
zgc:113279	zgc:113279	0.013
LOC100330224	fatty acid binding protein 1b-like	0.013
mical3	flavoprotein oxidoreductase MICAL3	0.013
ifnphi4	interferon phi 4	0.013
tcea3	transcription elongation factor A (SII), 3	0.013
zgc:110789	zgc:110789	0.013
zgc:77375	zgc:77375	0.012
slc41a1	solute carrier family 41, member 1	0.012
npy	neuropeptide Y	0.012
c1qa	complement component 1, q subcomponent, A chain	0.012
plekha7	pleckstrin homology domain containing, family A member 7	0.012
ptger4a	prostaglandin E receptor 4 (subtype EP4) a	0.012
cx28.6	connexin 28.6	0.012
ifit2	interferon-induced protein with tetratricopeptide repeats 2	0.012
cyp2k16	cytochrome P450, family 2, subfamily K, polypeptide16	0.012
zap70	zeta-chain (TCR) associated protein kinase	0.012
slc9a3.1	solute carrier family 9 (sodium/hydrogen exchanger), member 3.1	0.012
zswim6	zinc finger, SWIM-type containing 6	0.012
ftr29	finTRIM family, member 29	0.012
tnfb	tumor necrosis factor b (TNF superfamily, member 2)	0.012
zfpm2a	zinc finger protein, multitype 2a	0.012
il15	interleukin 15	0.012
kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.012
dntt	deoxynucleotidyltransferase, terminal	0.012
ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.012
ms4a17a.17	membrane-spanning 4-domains, subfamily A, member 17A.17	0.012
hcn4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.012
itm2bb	integral membrane protein 2Bb	0.012
ythdf1	YTH domain family, member 1	0.012
ugt5a1	UDP glucuronosyltransferase 5 family, polypeptide A1	0.012
zgc:114196	zgc:114196	0.012
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.012
ptpn3	protein tyrosine phosphatase, non-receptor type 3	0.012
sult1st6	sulfotransferase family 1, cytosolic sulfotransferase 6	0.012
irgq2	immunity-related GTPase family, q2	0.012
zgc:152741	zgc:152741	0.012
gygl	glycogenin, like	0.012
trim35	tripartite motif-containing 35	0.012
kcnc3b	potassium voltage-gated channel, Shaw-related subfamily, member 3b	0.012
LOC100003535	prostaglandin E2 receptor subtype EP1-like protein	0.011
LOC567504	interferon-induced protein with tetratricopeptide repeats 5-like	0.011
yth2	YTH domain family 2	0.011
slc9a2	solute carrier family 9 (sodium/hydrogen exchanger), member 2	0.011
si:dkeyp-27b10.2	si:dkeyp-27b10.2	0.011
f7	coagulation factor VII	0.011
LOC100005454	Gig2-like protein DreK	0.011
irf2	interferon regulatory factor 2	0.011
ddr2b	discoidin domain receptor family, member 2b	0.011
mpp6a	membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)	0.011
slc44a2	solute carrier family 44, member 2	0.011
LOC560177	zona pellucida-like domain-containing protein 1-like	0.011
cyp2n13	cytochrome P450, family 2, subfamily N, polypeptide 13	0.011
zgc:63599	zgc:63599	0.011
si:ch211-89f7.4	si:ch211-89f7.4	0.011
ugt5f1	UDP glucuronosyltransferase 5 family, polypeptide F1	0.011
hcst	hematopoietic cell signal transducer	0.011
lgals2a	lectin, galactoside-binding, soluble, 2a	0.011
abhd2a	abhydrolase domain containing 2a	0.011
LOC100333520	hypothetical protein LOC100333520	0.011
cd247l	CD247 antigen like	0.011
si:ch211-222e23.2	si:ch211-222e23.2	0.011
znf148	zinc finger protein 148	0.011
he2	hatching enzyme 2	0.011
LOC792676	similar to N-myc-interactor (Nmi) (N-myc and STAT interactor)	0.011
si:dkey-177e13.4	si:dkey-177e13.4	0.011
LOC100148845	neurogenin-1-like	0.011
cacna1ba	calcium channel, voltage-dependent, N type, alpha 1B subunit, a	0.011
cax1	cation/H+ exchanger protein 1	0.011
ercc4	excision repair cross-complementing rodent repair deficiency, complementation group 4	0.011
ccr12.2	chemokine (C-C motif) receptor 12.2	0.011
pcdh2aa1	protocadherin 2 alpha a 1	0.011
im:7147678	im:7147678	0.011
npy2r	neuropeptide Y receptor Y2	0.011
LOC100535037	leukotriene B4 receptor 1-like	0.011
zgc:103580	zgc:103580	0.011
crfb13	cytokine receptor family member b13	0.011
egf	epidermal growth factor	0.011
LOC567602	cadherin-1-like	0.011
papd7	PAP associated domain containing 7	0.011
ifnphi3	interferon phi 3	0.011
ccnl1	cyclin L1	0.011
igfbp2b	insulin-like growth factor binding protein 2b	0.011
ngfrl	nerve growth factor receptor (TNFR superfamily, member 16) like	0.011
esf1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	0.011
si:dkey-273o13.1	si:dkey-273o13.1	0.011
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.011
tef	thyrotroph embryonic factor	0.011
sirt2	sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)	0.011
ppargc1b	peroxisome proliferative activated receptor, gamma, coactivator 1, beta	0.011
cacna1bb	calcium channel, voltage-dependent, N type, alpha 1B subunit, b	0.011
zgc:171531	zgc:171531	0.011
si:dkeyp-95d10.1	si:dkeyp-95d10.1	0.011
brap	BRCA1 associated protein	0.011
rabep1	rabaptin, RAB GTPase binding effector protein 1	0.011
abcg2b	ATP-binding cassette, sub-family G (WHITE), member 2b	0.011
mgat3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase	0.011
phrf1	PHD and ring finger domains 1	0.011
LOC560057	prostaglandin E receptor 4, subtype EP4-like	0.011
cecr1b	cat eye syndrome chromosome region, candidate 1b	0.010
LOC795106	sterol 26-hydroxylase, mitochondrial-like	0.010
zgc:123207	zgc:123207	0.010
cyp4v2	cytochrome P450, family 4, subfamily V, polypeptide 2	0.010
LOC100149056	pannexin-3-like	0.010
LOC100001239	interferon-induced protein with tetratricopeptide repeats 5-like	0.010
abat	4-aminobutyrate aminotransferase	0.010
arhgap28	Rho GTPase activating protein 28	0.010
tlr4ba	toll-like receptor 4b, duplicate a	0.010
abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.010
slc45a2	solute carrier family 45, member 2	0.010
rapgef3	Rap guanine nucleotide exchange factor (GEF) 3	0.010
il17a/f2	interleukin 17a/f2	0.010
LOC100331628	tumor necrosis factor ligand superfamily member 11-like	0.010
LOC100005504	Gig2-like protein DreL	0.010
snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.010
abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.010
tas1r3	taste receptor, type 1, member 3	0.010
dapk3	death-associated protein kinase 3	0.010
uts2a	urotensin 2, alpha	0.010
zgc:109913	zgc:109913	0.010