The network for 'embryo development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryo development

The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.

Name Description Probability Func Analog Organism
SRSF1 serine/arginine-rich splicing factor 1 0.997
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.996
TP53 tumor protein p53 0.993
EGFR epidermal growth factor receptor 0.991
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.990
FN1 fibronectin 1 0.989
HDAC1 histone deacetylase 1 0.989
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.979
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.976
HDAC2 histone deacetylase 2 0.973
BRCA1 breast cancer 1, early onset 0.972
UBC ubiquitin C 0.971
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.971
ICT1 immature colon carcinoma transcript 1 0.968
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.965
C1QBP complement component 1, q subcomponent binding protein 0.965
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.964
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.962
SMAD2 SMAD family member 2 0.949
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.946
ILF3 interleukin enhancer binding factor 3, 90kDa 0.946
SMAD4 SMAD family member 4 0.937
SMAD3 SMAD family member 3 0.936
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.936
ATF2 activating transcription factor 2 0.933
DHX15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 0.926
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.916
MAPK14 mitogen-activated protein kinase 14 0.914
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.909
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.906
RPS6 ribosomal protein S6 0.904
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.893
SRSF7 serine/arginine-rich splicing factor 7 0.891
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.886
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.873
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.870
RPL6 ribosomal protein L6 0.868
TCP1 t-complex 1 0.867
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.859
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.855
EP300 E1A binding protein p300 0.855
APC adenomatous polyposis coli 0.838
CSNK2B casein kinase 2, beta polypeptide 0.835
JUN jun proto-oncogene 0.831
SRPK2 SRSF protein kinase 2 0.830
SRSF2 serine/arginine-rich splicing factor 2 0.829
ESR1 estrogen receptor 1 0.824
CUL3 cullin 3 0.822
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.813
PCGF2 polycomb group ring finger 2 0.809
CREBBP CREB binding protein 0.808
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.799
SRSF3 serine/arginine-rich splicing factor 3 0.783
MRPL3 mitochondrial ribosomal protein L3 0.776
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.773
RPS8 ribosomal protein S8 0.771
RPL14 ribosomal protein L14 0.755
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.750
PGK1 phosphoglycerate kinase 1 0.746
CDC23 cell division cycle 23 homolog (S. cerevisiae) 0.738
PHB prohibitin 0.737
TARDBP TAR DNA binding protein 0.736
SRPK1 SRSF protein kinase 1 0.716
IQGAP1 IQ motif containing GTPase activating protein 1 0.715
RB1 retinoblastoma 1 0.708
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.706
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.702
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.702
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.696
PPP1R12A protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.695
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.693
RHOA ras homolog gene family, member A 0.692
FLNA filamin A, alpha 0.691
RFC4 replication factor C (activator 1) 4, 37kDa 0.684
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.671
COL1A1 collagen, type I, alpha 1 0.669
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.669
PSEN1 presenilin 1 0.665
CDK2 cyclin-dependent kinase 2 0.662
CYC1 cytochrome c-1 0.660
MCM3 minichromosome maintenance complex component 3 0.649
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.648
NCOR1 nuclear receptor corepressor 1 0.643
EIF4A3 eukaryotic translation initiation factor 4A3 0.643
FGFR1 fibroblast growth factor receptor 1 0.639
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.632
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.630
NUDC nuclear distribution gene C homolog (A. nidulans) 0.625
EPS15 epidermal growth factor receptor pathway substrate 15 0.621
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.612
RPS4X ribosomal protein S4, X-linked 0.608
SUMO2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) 0.606
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.606
DAXX death-domain associated protein 0.603
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.603
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.600
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.598
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.589
SEC23A Sec23 homolog A (S. cerevisiae) 0.588
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.584
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
mom-2 Protein MOM-2 0.998
egl-18 Protein EGL-18 0.997
rnr-1 Protein RNR-1 0.997
pal-1 Protein PAL-1 0.994
dlc-1 Protein DLC-1 0.994
nhr-2 Protein NHR-2 0.991
scc-1 Protein SCC-1 0.990
his-45 Protein HIS-45 0.990
eef-1A.1 Protein EEF-1A.1 0.989
mes-3 Protein MES-3 0.989
his-64 Protein HIS-64 0.989
F01G4.6 Protein F01G4.6 0.989
prp-3 Protein PRP-3 0.989
swd-2.2 Protein SWD-2.2 0.987
mcm-7 Protein MCM-7 0.987
stip-1 Protein STIP-1 0.984
sas-5 Protein SAS-5 0.984
vab-3 Protein VAB-3 0.983
san-1 Protein SAN-1 0.983
his-46 Protein HIS-46 0.983
npp-11 Protein NPP-11 0.982
hcp-3 Protein HCP-3 0.982
dao-5 Protein DAO-5 0.982
rars-1 Protein RARS-1 0.981
let-99 Protein LET-99 0.981
par-5 Protein PAR-5 0.981
tag-170 Protein TAG-170 0.980
his-68 Protein HIS-68 0.980
rpl-4 Protein RPL-4 0.980
mrps-18B Protein MRPS-18B 0.978
mig-5 Protein MIG-5 0.978
skr-2 Protein SKR-2 0.977
skr-7 Protein SKR-7 0.977
cam-1 Protein CAM-1 0.976
icd-1 Protein ICD-1 0.975
tba-1 Protein TBA-1 0.974
pch-2 Protein PCH-2 0.974
elt-6 Protein ELT-6 0.973
asb-2 Protein ASB-2 0.972
hsp-1 Protein HSP-1 0.972
his-16 Protein HIS-16 0.972
aos-1 Protein AOS-1 0.970
klp-16 Protein KLP-16 0.969
rbx-1 Protein RBX-1 0.969
pab-1 Protein PAB-1 0.968
flh-1 Protein FLH-1 0.968
his-5 Protein HIS-5 0.968
his-62 Protein HIS-62 0.965
npp-1 Protein NPP-1 0.965
bir-1 Protein BIR-1 0.964
hcp-4 Protein HCP-4 0.964
mig-6 Protein MIG-6 0.963
abce-1 Protein ABCE-1 0.961
ndc-80 Protein NDC-80 0.961
fkb-6 Protein FKB-6 0.961
spn-4 Protein SPN-4 0.960
patr-1 Protein PATR-1 0.959
apc-11 Protein APC-11 0.959
epg-8 Protein EPG-8 0.958
ubc-12 Protein UBC-12 0.957
F53B7.3 Protein F53B7.3 0.957
T11G6.8 Protein T11G6.8 0.956
snr-5 Protein SNR-5 0.956
C44E4.4 Protein C44E4.4 0.953
ran-1 Protein RAN-1 0.953
pqn-59 Protein PQN-59 0.953
bub-1 Protein BUB-1 0.952
ptr-2 Protein PTR-2 0.952
pos-1 Protein POS-1 0.952
rack-1 Protein RACK-1 0.951
rpl-7 Protein RPL-7 0.951
W08E12.7 Protein W08E12.7 0.951
mel-11 Protein MEL-11 0.951
prg-1 Protein PRG-1 0.950
sbds-1 Protein SBDS-1 0.950
unc-37 Protein UNC-37 0.950
ify-1 Protein IFY-1 0.949
dsh-2 Protein DSH-2 0.949
hcp-1 Protein HCP-1 0.948
his-1 Protein HIS-1 0.948
lsy-22 Protein LSY-22 0.948
mat-3 Protein MAT-3 0.946
pfd-1 Protein PFD-1 0.946
mcm-6 Protein MCM-6 0.945
npp-15 Protein NPP-15 0.944
Y110A7A.4 Protein Y110A7A.4 0.944
dhfr-1 Protein DHFR-1 0.944
H28O16.1 Protein H28O16.1 0.944
hpo-35 Protein HPO-35 0.943
dlat-1 Protein DLAT-1 0.942
pat-4 Protein PAT-4 0.942
hda-1 Protein HDA-1 0.941
his-31 Protein HIS-31 0.941
Y47D3A.29 Protein Y47D3A.29 0.941
nap-1 Protein NAP-1 0.941
brc-1 Protein BRC-1 0.940
skn-1 Protein SKN-1 0.939
rad-50 Protein RAD-50 0.939
CELE_F19F10.9 Protein F19F10.9 0.938
wdr-46 Protein WDR-46 0.937
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Tgfbr2 transforming growth factor, beta receptor II 0.264
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.224
Smad7 SMAD family member 7 0.187
Psgb1 pregnancy-specific beta 1-glycoprotein 0.186
Sirpa signal-regulatory protein alpha 0.149
Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.130
Col12a1 collagen, type XII, alpha 1 0.126
Cnbp CCHC-type zinc finger, nucleic acid binding protein 0.118
Psmb3 proteasome (prosome, macropain) subunit, beta type 3 0.110
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.110
Irs1 insulin receptor substrate 1 0.100
Cald1 caldesmon 1 0.097
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.095
Trim47 tripartite motif-containing 47 0.086
Eln elastin 0.082
Tcfe2a transcription factor E2a 0.079
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.079
Myh9 myosin, heavy chain 9, non-muscle 0.078
Actb actin, beta 0.076
Tars threonyl-tRNA synthetase 0.075
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.073
Sdc3 syndecan 3 0.073
Col5a2 collagen, type V, alpha 2 0.073
Lamc1 laminin, gamma 1 0.073
Dusp1 dual specificity phosphatase 1 0.072
Fgfr2 fibroblast growth factor receptor 2 0.072
Met met proto-oncogene 0.071
Bcl2 B-cell CLL/lymphoma 2 0.071
Egr2 early growth response 2 0.071
Rhob ras homolog gene family, member B 0.071
Rara retinoic acid receptor, alpha 0.070
Fn1 fibronectin 1 0.069
Flt1 FMS-related tyrosine kinase 1 0.069
Psma5 proteasome (prosome, macropain) subunit, alpha type 5 0.068
Acvr1 activin A receptor, type I 0.066
Tpm3 tropomyosin 3, gamma 0.064
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.061
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.060
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.059
Col1a2 collagen, type I, alpha 2 0.058
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.058
Foxd3 forkhead box D3 0.057
Myo1b myosin Ib 0.056
Jak1 Janus kinase 1 0.056
Neurog1 neurogenin 1 0.056
Tubb5 tubulin, beta 5 0.055
Hoxb7 homeo box B7 0.054
Clic4 chloride intracellular channel 4 0.053
Tp53 tumor protein p53 0.052
Foxc2 forkhead box C2 0.052
Flna filamin A, alpha 0.051
Dchs1 dachsous 1 (Drosophila) 0.051
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.051
Krt18 keratin 18 0.051
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.051
Rhoa ras homolog gene family, member A 0.050
Wdr26 WD repeat domain 26 0.050
Sfrs2 splicing factor, arginine/serine-rich 2 0.049
Prrx1 paired related homeobox 1 0.049
Dapk3 death-associated protein kinase 3 0.049
Sox17 SRY (sex determining region Y)-box 17 0.049
Gast gastrin 0.049
Acta2 smooth muscle alpha-actin 0.049
Rap1b RAP1B, member of RAS oncogene family 0.048
Grasp GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.048
Psma4 proteasome (prosome, macropain) subunit, alpha type 4 0.048
Abi1 abl-interactor 1 0.048
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.048
Junb jun B proto-oncogene 0.047
Myo1e myosin IE 0.047
Bgn biglycan 0.046
Ptprc protein tyrosine phosphatase, receptor type, C 0.046
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.046
Arih1 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) 0.045
Kl Klotho 0.045
Psma3 proteasome (prosome, macropain) subunit, alpha type 3 0.045
Dlg1 discs, large homolog 1 (Drosophila) 0.045
Timp3 TIMP metallopeptidase inhibitor 3 0.045
Lig3 ligase III, DNA, ATP-dependent 0.043
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.043
Dact3 dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis) 0.043
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.043
Aqp2 aquaporin 2 (collecting duct) 0.043
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.042
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.042
Ptpn1 protein tyrosine phosphatase, non-receptor type 1 0.041
Bmp6 bone morphogenetic protein 6 0.041
Nab1 Ngfi-A binding protein 1 0.041
Ccnb2 cyclin B2 0.041
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.041
Chrng cholinergic receptor, nicotinic, gamma 0.041
Cand1 cullin-associated and neddylation-dissociated 1 0.040
Runx1 runt-related transcription factor 1 0.040
Jun Jun oncogene 0.039
Gja5 gap junction protein, alpha 5 0.039
Prkch protein kinase C, eta 0.039
Nsfl1c NSFL1 (p97) cofactor (p47) 0.039
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.039
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.039
Ins2 insulin 2 0.039
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism