The network for 'positive regulation of mononuclear cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of mononuclear cell proliferation

Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.

Name Description Probability Func Analog Organism
GRB2 growth factor receptor-bound protein 2 0.999
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.985
HLA-DRA major histocompatibility complex, class II, DR alpha 0.954
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.951
FGFR2 fibroblast growth factor receptor 2 0.943
BCL2 B-cell CLL/lymphoma 2 0.883
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.864
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.829
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.798
CD80 CD80 molecule 0.766
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.744
IL1R1 interleukin 1 receptor, type I 0.733
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.692
BTN3A3 butyrophilin, subfamily 3, member A3 0.648
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.634
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.631
SOCS3 suppressor of cytokine signaling 3 0.617
IRAK1 interleukin-1 receptor-associated kinase 1 0.595
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.545
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.506
CCR5 chemokine (C-C motif) receptor 5 0.499
LCK lymphocyte-specific protein tyrosine kinase 0.496
TICAM2 toll-like receptor adaptor molecule 2 0.485
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.481
CD86 CD86 molecule 0.479
LST1 leukocyte specific transcript 1 0.476
ICAM1 intercellular adhesion molecule 1 0.474
CCL4 chemokine (C-C motif) ligand 4 0.446
BCL2L1 BCL2-like 1 0.428
IL2RB interleukin 2 receptor, beta 0.418
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.400
LAT linker for activation of T cells 0.398
CCR7 chemokine (C-C motif) receptor 7 0.391
CXCL9 chemokine (C-X-C motif) ligand 9 0.382
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.364
IL1B interleukin 1, beta 0.359
HLA-DMA major histocompatibility complex, class II, DM alpha 0.345
IL8 interleukin 8 0.303
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.298
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 0.298
CCL2 chemokine (C-C motif) ligand 2 0.295
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.295
SYK spleen tyrosine kinase 0.284
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.276
IL6 interleukin 6 (interferon, beta 2) 0.263
CCL22 chemokine (C-C motif) ligand 22 0.261
BTN3A2 butyrophilin, subfamily 3, member A2 0.257
CCL13 chemokine (C-C motif) ligand 13 0.255
JAK1 Janus kinase 1 0.247
BCL10 B-cell CLL/lymphoma 10 0.241
IL2RG interleukin 2 receptor, gamma 0.241
TRAF3IP3 TRAF3 interacting protein 3 0.237
TRAF6 TNF receptor-associated factor 6 0.232
CCL8 chemokine (C-C motif) ligand 8 0.221
CXCL2 chemokine (C-X-C motif) ligand 2 0.213
RUNX1 runt-related transcription factor 1 0.210
PLCG1 phospholipase C, gamma 1 0.209
IRF4 interferon regulatory factor 4 0.200
SLA Src-like-adaptor 0.198
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.197
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.191
FGF1 fibroblast growth factor 1 (acidic) 0.182
MYD88 myeloid differentiation primary response gene (88) 0.178
GAS7 growth arrest-specific 7 0.177
IRAK2 interleukin-1 receptor-associated kinase 2 0.177
STAT4 signal transducer and activator of transcription 4 0.172
INSR insulin receptor 0.170
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.167
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.164
FGFR1 fibroblast growth factor receptor 1 0.159
IL10 interleukin 10 0.158
HDAC9 histone deacetylase 9 0.157
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.152
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.150
BTK Bruton agammaglobulinemia tyrosine kinase 0.148
GRB10 growth factor receptor-bound protein 10 0.148
BCAR1 breast cancer anti-estrogen resistance 1 0.143
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.139
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.139
IL4R interleukin 4 receptor 0.138
NLRP3 NLR family, pyrin domain containing 3 0.137
SIGLEC7 sialic acid binding Ig-like lectin 7 0.132
PILRA paired immunoglobin-like type 2 receptor alpha 0.131
TRAF1 TNF receptor-associated factor 1 0.131
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.129
CXCL3 chemokine (C-X-C motif) ligand 3 0.129
BTN3A1 butyrophilin, subfamily 3, member A1 0.125
TAL1 T-cell acute lymphocytic leukemia 1 0.125
GRAP2 GRB2-related adaptor protein 2 0.121
CCR1 chemokine (C-C motif) receptor 1 0.118
BID BH3 interacting domain death agonist 0.117
AOAH acyloxyacyl hydrolase (neutrophil) 0.114
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.112
IL1R2 interleukin 1 receptor, type II 0.110
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.109
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.108
HCK hemopoietic cell kinase 0.107
CD1C CD1c molecule 0.106
SLAMF1 signaling lymphocytic activation molecule family member 1 0.106
CSK c-src tyrosine kinase 0.104
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-Db1 RT1 class II, locus Db1 0.209
RT1-Da RT1 class II, locus Da 0.132
Cd247 Cd247 molecule 0.115
Tcrb T-cell receptor beta chain 0.088
RT1-Ba RT1 class II, locus Ba 0.064
Cd5 Cd5 molecule 0.052
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.050
Lcp1 lymphocyte cytosolic protein 1 0.048
Cd53 Cd53 molecule 0.047
Il10 interleukin 10 0.046
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.045
Cd37 CD37 molecule 0.042
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.040
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.040
Il1b interleukin 1 beta 0.038
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.036
Gzmk granzyme K 0.035
Ptprc protein tyrosine phosphatase, receptor type, C 0.033
Kl Klotho 0.032
Sash3 SAM and SH3 domain containing 3 0.032
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.031
Cd2 Cd2 molecule 0.029
Hck hemopoietic cell kinase 0.029
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.028
Calcr calcitonin receptor 0.027
Il1rl1 interleukin 1 receptor-like 1 0.027
Itgad integrin, alpha D 0.025
Plin perilipin 0.024
Trpm8 transient receptor potential cation channel, subfamily M, member 8 0.024
Ncr1 natural cytotoxicity triggering receptor 1 0.024
Mmp10 matrix metallopeptidase 10 0.024
Prss1 protease, serine, 1 (trypsin 1) 0.024
Il1r1 interleukin 1 receptor, type I 0.024
Inpp5d inositol polyphosphate-5-phosphatase D 0.023
Syt8 synaptotagmin VIII 0.023
Ccl5 chemokine (C-C motif) ligand 5 0.023
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 0.023
Serpinb2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.023
Prl8a9 prolactin family 8, subfamily a, member 9 0.022
Ptafr platelet-activating factor receptor 0.022
Arhgap4 Rho GTPase activating protein 4 0.022
Psp parotid secretory protein 0.022
Scn11a sodium channel, voltage-gated, type XI, alpha 0.021
Vip vasoactive intestinal peptide 0.020
Vom1r90 vomeronasal 1 receptor 90 0.020
Nkg7 natural killer cell group 7 sequence 0.019
Olr1500 olfactory receptor 1500 0.019
Reg3g regenerating islet-derived 3 gamma 0.019
Il2rb interleukin 2 receptor, beta 0.019
Cfp complement factor properdin 0.019
Itgb7 integrin, beta 7 0.019
Oprk1 opioid receptor, kappa 1 0.018
Zbp1 Z-DNA binding protein 1 0.018
Spn sialophorin 0.018
Reg3b regenerating islet-derived 3 beta 0.017
Impg2 interphotoreceptor matrix proteoglycan 2 0.017
Inhbe inhibin beta E 0.017
Pth parathyroid hormone 0.017
Csn1s1 casein alpha s1 0.017
Npy5r neuropeptide Y receptor Y5 0.017
Trh thyrotropin releasing hormone 0.017
Lhfpl2 lipoma HMGIC fusion partner-like 2 0.017
Olr1496 olfactory receptor 1496 0.016
Dnase1l3 deoxyribonuclease 1-like 3 0.016
Ucn urocortin 0.015
Ccr5 chemokine (C-C motif) receptor 5 0.015
Il6 interleukin 6 0.015
Laptm5 lysosomal protein transmembrane 5 0.015
Crisp1 cysteine-rich secretory protein 1 0.015
Crygc crystallin, gamma C 0.015
Chrnb3 cholinergic receptor, nicotinic, beta 3 0.015
Il4 interleukin 4 0.014
Kcnv1 potassium channel, subfamily V, member 1 0.014
Slco1a5 solute carrier organic anion transporter family, member 1a5 0.014
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.014
Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.014
Pmfbp1 polyamine modulated factor 1 binding protein 1 0.014
Faslg Fas ligand (TNF superfamily, member 6) 0.014
Srd5a2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 0.014
Olah oleoyl-ACP hydrolase 0.014
Napsa napsin A aspartic peptidase 0.014
Kcng3 potassium voltage-gated channel, subfamily G, member 3 0.014
Psg19 pregnancy specific glycoprotein 19 0.014
Dgkg diacylglycerol kinase, gamma 0.014
Vom2r32 vomeronasal 2 receptor, 32 0.014
Scp2 sterol carrier protein 2 0.014
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.014
Casp1 caspase 1 0.013
LOC689770 similar to osteoclast inhibitory lectin 0.013
Gja3 gap junction protein, alpha 3 0.013
Ncf4 neutrophil cytosolic factor 4 0.013
Mamdc4 MAM domain containing 4 0.013
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.013
Met met proto-oncogene 0.013
Oprl1 opiate receptor-like 1 0.013
Bin2 bridging integrator 2 0.013
Npffr1 neuropeptide FF receptor 1 0.012
Sell selectin L 0.012
Ugt8 UDP glycosyltransferase 8 0.012
Cpxm2 carboxypeptidase X (M14 family), member 2 0.012
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism