Process View
The network for 'positive regulation of mononuclear cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
GRB2 | growth factor receptor-bound protein 2 | 0.999 | |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.985 | |
HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.954 | |
ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.951 | |
FGFR2 | fibroblast growth factor receptor 2 | 0.943 | |
BCL2 | B-cell CLL/lymphoma 2 | 0.883 | |
LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.864 | |
CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.829 | |
TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.798 | |
CD80 | CD80 molecule | 0.766 | |
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.744 | |
IL1R1 | interleukin 1 receptor, type I | 0.733 | |
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.692 | |
BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.648 | |
LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.634 | |
IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.631 | |
SOCS3 | suppressor of cytokine signaling 3 | 0.617 | |
IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.595 | |
LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 0.545 | |
CTLA4 | cytotoxic T-lymphocyte-associated protein 4 | 0.506 | |
CCR5 | chemokine (C-C motif) receptor 5 | 0.499 | |
LCK | lymphocyte-specific protein tyrosine kinase | 0.496 | |
TICAM2 | toll-like receptor adaptor molecule 2 | 0.485 | |
LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.481 | |
CD86 | CD86 molecule | 0.479 | |
LST1 | leukocyte specific transcript 1 | 0.476 | |
ICAM1 | intercellular adhesion molecule 1 | 0.474 | |
CCL4 | chemokine (C-C motif) ligand 4 | 0.446 | |
BCL2L1 | BCL2-like 1 | 0.428 | |
IL2RB | interleukin 2 receptor, beta | 0.418 | |
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.400 | |
LAT | linker for activation of T cells | 0.398 | |
CCR7 | chemokine (C-C motif) receptor 7 | 0.391 | |
CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.382 | |
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.364 | |
IL1B | interleukin 1, beta | 0.359 | |
HLA-DMA | major histocompatibility complex, class II, DM alpha | 0.345 | |
IL8 | interleukin 8 | 0.303 | |
CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.298 | |
HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 | 0.298 | |
CCL2 | chemokine (C-C motif) ligand 2 | 0.295 | |
PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.295 | |
SYK | spleen tyrosine kinase | 0.284 | |
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.276 | |
IL6 | interleukin 6 (interferon, beta 2) | 0.263 | |
CCL22 | chemokine (C-C motif) ligand 22 | 0.261 | |
BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.257 | |
CCL13 | chemokine (C-C motif) ligand 13 | 0.255 | |
JAK1 | Janus kinase 1 | 0.247 | |
BCL10 | B-cell CLL/lymphoma 10 | 0.241 | |
IL2RG | interleukin 2 receptor, gamma | 0.241 | |
TRAF3IP3 | TRAF3 interacting protein 3 | 0.237 | |
TRAF6 | TNF receptor-associated factor 6 | 0.232 | |
CCL8 | chemokine (C-C motif) ligand 8 | 0.221 | |
CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.213 | |
RUNX1 | runt-related transcription factor 1 | 0.210 | |
PLCG1 | phospholipase C, gamma 1 | 0.209 | |
IRF4 | interferon regulatory factor 4 | 0.200 | |
SLA | Src-like-adaptor | 0.198 | |
BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.197 | |
LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.191 | |
FGF1 | fibroblast growth factor 1 (acidic) | 0.182 | |
MYD88 | myeloid differentiation primary response gene (88) | 0.178 | |
GAS7 | growth arrest-specific 7 | 0.177 | |
IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.177 | |
STAT4 | signal transducer and activator of transcription 4 | 0.172 | |
INSR | insulin receptor | 0.170 | |
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.167 | |
IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.164 | |
FGFR1 | fibroblast growth factor receptor 1 | 0.159 | |
IL10 | interleukin 10 | 0.158 | |
HDAC9 | histone deacetylase 9 | 0.157 | |
CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.152 | |
LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.150 | |
BTK | Bruton agammaglobulinemia tyrosine kinase | 0.148 | |
GRB10 | growth factor receptor-bound protein 10 | 0.148 | |
BCAR1 | breast cancer anti-estrogen resistance 1 | 0.143 | |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.139 | |
CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.139 | |
IL4R | interleukin 4 receptor | 0.138 | |
NLRP3 | NLR family, pyrin domain containing 3 | 0.137 | |
SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.132 | |
PILRA | paired immunoglobin-like type 2 receptor alpha | 0.131 | |
TRAF1 | TNF receptor-associated factor 1 | 0.131 | |
LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.129 | |
CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.129 | |
BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.125 | |
TAL1 | T-cell acute lymphocytic leukemia 1 | 0.125 | |
GRAP2 | GRB2-related adaptor protein 2 | 0.121 | |
CCR1 | chemokine (C-C motif) receptor 1 | 0.118 | |
BID | BH3 interacting domain death agonist | 0.117 | |
AOAH | acyloxyacyl hydrolase (neutrophil) | 0.114 | |
CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.112 | |
IL1R2 | interleukin 1 receptor, type II | 0.110 | |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.109 | |
MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.108 | |
HCK | hemopoietic cell kinase | 0.107 | |
CD1C | CD1c molecule | 0.106 | |
SLAMF1 | signaling lymphocytic activation molecule family member 1 | 0.106 | |
CSK | c-src tyrosine kinase | 0.104 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
RT1-Db1 | RT1 class II, locus Db1 | 0.209 | |
RT1-Da | RT1 class II, locus Da | 0.132 | |
Cd247 | Cd247 molecule | 0.115 | |
Tcrb | T-cell receptor beta chain | 0.088 | |
RT1-Ba | RT1 class II, locus Ba | 0.064 | |
Cd5 | Cd5 molecule | 0.052 | |
Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.050 | |
Lcp1 | lymphocyte cytosolic protein 1 | 0.048 | |
Cd53 | Cd53 molecule | 0.047 | |
Il10 | interleukin 10 | 0.046 | |
Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.045 | |
Cd37 | CD37 molecule | 0.042 | |
Slc18a2 | solute carrier family 18 (vesicular monoamine), member 2 | 0.040 | |
Acap1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | 0.040 | |
Il1b | interleukin 1 beta | 0.038 | |
Ptger4 | prostaglandin E receptor 4 (subtype EP4) | 0.036 | |
Gzmk | granzyme K | 0.035 | |
Ptprc | protein tyrosine phosphatase, receptor type, C | 0.033 | |
Kl | Klotho | 0.032 | |
Sash3 | SAM and SH3 domain containing 3 | 0.032 | |
Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.031 | |
Cd2 | Cd2 molecule | 0.029 | |
Hck | hemopoietic cell kinase | 0.029 | |
P2rx2 | purinergic receptor P2X, ligand-gated ion channel, 2 | 0.028 | |
Calcr | calcitonin receptor | 0.027 | |
Il1rl1 | interleukin 1 receptor-like 1 | 0.027 | |
Itgad | integrin, alpha D | 0.025 | |
Plin | perilipin | 0.024 | |
Trpm8 | transient receptor potential cation channel, subfamily M, member 8 | 0.024 | |
Ncr1 | natural cytotoxicity triggering receptor 1 | 0.024 | |
Mmp10 | matrix metallopeptidase 10 | 0.024 | |
Prss1 | protease, serine, 1 (trypsin 1) | 0.024 | |
Il1r1 | interleukin 1 receptor, type I | 0.024 | |
Inpp5d | inositol polyphosphate-5-phosphatase D | 0.023 | |
Syt8 | synaptotagmin VIII | 0.023 | |
Ccl5 | chemokine (C-C motif) ligand 5 | 0.023 | |
Htr1b | 5-hydroxytryptamine (serotonin) receptor 1B | 0.023 | |
Serpinb2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.023 | |
Prl8a9 | prolactin family 8, subfamily a, member 9 | 0.022 | |
Ptafr | platelet-activating factor receptor | 0.022 | |
Arhgap4 | Rho GTPase activating protein 4 | 0.022 | |
Psp | parotid secretory protein | 0.022 | |
Scn11a | sodium channel, voltage-gated, type XI, alpha | 0.021 | |
Vip | vasoactive intestinal peptide | 0.020 | |
Vom1r90 | vomeronasal 1 receptor 90 | 0.020 | |
Nkg7 | natural killer cell group 7 sequence | 0.019 | |
Olr1500 | olfactory receptor 1500 | 0.019 | |
Reg3g | regenerating islet-derived 3 gamma | 0.019 | |
Il2rb | interleukin 2 receptor, beta | 0.019 | |
Cfp | complement factor properdin | 0.019 | |
Itgb7 | integrin, beta 7 | 0.019 | |
Oprk1 | opioid receptor, kappa 1 | 0.018 | |
Zbp1 | Z-DNA binding protein 1 | 0.018 | |
Spn | sialophorin | 0.018 | |
Reg3b | regenerating islet-derived 3 beta | 0.017 | |
Impg2 | interphotoreceptor matrix proteoglycan 2 | 0.017 | |
Inhbe | inhibin beta E | 0.017 | |
Pth | parathyroid hormone | 0.017 | |
Csn1s1 | casein alpha s1 | 0.017 | |
Npy5r | neuropeptide Y receptor Y5 | 0.017 | |
Trh | thyrotropin releasing hormone | 0.017 | |
Lhfpl2 | lipoma HMGIC fusion partner-like 2 | 0.017 | |
Olr1496 | olfactory receptor 1496 | 0.016 | |
Dnase1l3 | deoxyribonuclease 1-like 3 | 0.016 | |
Ucn | urocortin | 0.015 | |
Ccr5 | chemokine (C-C motif) receptor 5 | 0.015 | |
Il6 | interleukin 6 | 0.015 | |
Laptm5 | lysosomal protein transmembrane 5 | 0.015 | |
Crisp1 | cysteine-rich secretory protein 1 | 0.015 | |
Crygc | crystallin, gamma C | 0.015 | |
Chrnb3 | cholinergic receptor, nicotinic, beta 3 | 0.015 | |
Il4 | interleukin 4 | 0.014 | |
Kcnv1 | potassium channel, subfamily V, member 1 | 0.014 | |
Slco1a5 | solute carrier organic anion transporter family, member 1a5 | 0.014 | |
Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.014 | |
Ugt2b7 | UDP glucuronosyltransferase 2 family, polypeptide B7 | 0.014 | |
Pmfbp1 | polyamine modulated factor 1 binding protein 1 | 0.014 | |
Faslg | Fas ligand (TNF superfamily, member 6) | 0.014 | |
Srd5a2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 0.014 | |
Olah | oleoyl-ACP hydrolase | 0.014 | |
Napsa | napsin A aspartic peptidase | 0.014 | |
Kcng3 | potassium voltage-gated channel, subfamily G, member 3 | 0.014 | |
Psg19 | pregnancy specific glycoprotein 19 | 0.014 | |
Dgkg | diacylglycerol kinase, gamma | 0.014 | |
Vom2r32 | vomeronasal 2 receptor, 32 | 0.014 | |
Scp2 | sterol carrier protein 2 | 0.014 | |
St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.014 | |
Casp1 | caspase 1 | 0.013 | |
LOC689770 | similar to osteoclast inhibitory lectin | 0.013 | |
Gja3 | gap junction protein, alpha 3 | 0.013 | |
Ncf4 | neutrophil cytosolic factor 4 | 0.013 | |
Mamdc4 | MAM domain containing 4 | 0.013 | |
Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.013 | |
Met | met proto-oncogene | 0.013 | |
Oprl1 | opiate receptor-like 1 | 0.013 | |
Bin2 | bridging integrator 2 | 0.013 | |
Npffr1 | neuropeptide FF receptor 1 | 0.012 | |
Sell | selectin L | 0.012 | |
Ugt8 | UDP glycosyltransferase 8 | 0.012 | |
Cpxm2 | carboxypeptidase X (M14 family), member 2 | 0.012 |