IMP
Process View
The network for 'negative regulation of cell motility' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of cell motility
Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 1.000 | |
| FN1 | fibronectin 1 | 0.994 | |
| FGFR2 | fibroblast growth factor receptor 2 | 0.975 | |
| ENG | endoglin | 0.973 | |
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.971 | |
| JAG1 | jagged 1 | 0.967 | |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.966 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.939 | |
| TEK | TEK tyrosine kinase, endothelial | 0.935 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.930 | |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.920 | |
| KRT15 | keratin 15 | 0.874 | |
| FLNA | filamin A, alpha | 0.869 | |
| THBS1 | thrombospondin 1 | 0.828 | |
| VCAM1 | vascular cell adhesion molecule 1 | 0.819 | |
| BMP2 | bone morphogenetic protein 2 | 0.809 | |
| TGFB1 | transforming growth factor, beta 1 | 0.765 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.706 | |
| IFITM2 | interferon induced transmembrane protein 2 (1-8D) | 0.661 | |
| IFITM1 | interferon induced transmembrane protein 1 (9-27) | 0.659 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.657 | |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.655 | |
| HOXB5 | homeobox B5 | 0.653 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.635 | |
| TBX5 | T-box 5 | 0.633 | |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.630 | |
| IFITM3 | interferon induced transmembrane protein 3 (1-8U) | 0.628 | |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.622 | |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.617 | |
| APOE | apolipoprotein E | 0.611 | |
| NOTCH3 | notch 3 | 0.561 | |
| NCOA1 | nuclear receptor coactivator 1 | 0.548 | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.537 | |
| NOTCH1 | notch 1 | 0.505 | |
| EMP3 | epithelial membrane protein 3 | 0.495 | |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.490 | |
| KRT8 | keratin 8 | 0.479 | |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.464 | |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.455 | |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) | 0.441 | |
| SMAD3 | SMAD family member 3 | 0.437 | |
| KRT6B | keratin 6B | 0.434 | |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.426 | |
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.422 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.418 | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.408 | |
| HTT | huntingtin | 0.401 | |
| ESRRG | estrogen-related receptor gamma | 0.392 | |
| GRB7 | growth factor receptor-bound protein 7 | 0.378 | |
| BAIAP2 | BAI1-associated protein 2 | 0.376 | |
| ACVR1 | activin A receptor, type I | 0.364 | |
| ANGPT2 | angiopoietin 2 | 0.364 | |
| COL1A1 | collagen, type I, alpha 1 | 0.346 | |
| COX17 | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.343 | |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.335 | |
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.334 | |
| APOC1 | apolipoprotein C-I | 0.328 | |
| ABI2 | abl-interactor 2 | 0.327 | |
| TBXA2R | thromboxane A2 receptor | 0.324 | |
| VCAN | versican | 0.321 | |
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.318 | |
| VCL | vinculin | 0.308 | |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.308 | |
| JUN | jun proto-oncogene | 0.306 | |
| CD63 | CD63 molecule | 0.301 | |
| STRN3 | striatin, calmodulin binding protein 3 | 0.301 | |
| ADRB1 | adrenergic, beta-1-, receptor | 0.298 | |
| NCOR1 | nuclear receptor corepressor 1 | 0.292 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.290 | |
| BMP1 | bone morphogenetic protein 1 | 0.290 | |
| NPR1 | natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | 0.289 | |
| ADORA2A | adenosine A2a receptor | 0.285 | |
| HOXB6 | homeobox B6 | 0.284 | |
| ZNF746 | zinc finger protein 746 | 0.284 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.283 | |
| MEF2A | myocyte enhancer factor 2A | 0.282 | |
| C1QB | complement component 1, q subcomponent, B chain | 0.281 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.277 | |
| MEF2C | myocyte enhancer factor 2C | 0.274 | |
| PLAT | plasminogen activator, tissue | 0.272 | |
| PKP1 | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 0.271 | |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.270 | |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.268 | |
| ALB | albumin | 0.267 | |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.265 | |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.263 | |
| ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.261 | |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.261 | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.258 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.258 | |
| KRT6A | keratin 6A | 0.254 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.253 | |
| PVRL3 | poliovirus receptor-related 3 | 0.250 | |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.250 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.248 | |
| TGFB3 | transforming growth factor, beta 3 | 0.248 | |
| BCL6 | B-cell CLL/lymphoma 6 | 0.240 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.237 | |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.236 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.234 |
Loading network...
Danio rerio
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| kdrl | kinase insert domain receptor like | 0.385 | |
| efnb2a | ephrin B2a | 0.354 | |
| notch3 | notch homolog 3 | 0.160 | |
| jag1b | jagged 1b | 0.150 | |
| sulf1 | sulfatase 1 | 0.104 | |
| utrn | utrophin | 0.102 | |
| lhx2b | LIM homeobox 2b | 0.092 | |
| dlc | deltaC | 0.090 | |
| tbx1 | T-box 1 | 0.088 | |
| itgb1b.2 | integrin, beta 1b.2 | 0.087 | |
| ilk | integrin linked kinase | 0.087 | |
| fgf3 | fibroblast growth factor 3 | 0.086 | |
| mmp2 | matrix metalloproteinase 2 | 0.083 | |
| clstn1 | calsyntenin 1 | 0.075 | |
| lmx1b.1 | LIM homeobox transcription factor 1, beta 1 | 0.066 | |
| ntn1a | netrin 1a | 0.065 | |
| fgfr2 | fibroblast growth factor receptor 2 | 0.064 | |
| dtng | dystrobrevin, gamma and dystrobrevin, gamma-like | 0.063 | |
| nf1a | neurofibromin 1a | 0.063 | |
| prkci | protein kinase C, iota | 0.059 | |
| gli1 | GLI-Kruppel family member 1 | 0.059 | |
| midn | midnolin | 0.058 | |
| notch1a | notch homolog 1a | 0.057 | |
| gcm2 | glial cells missing homolog 2 (Drosophila) | 0.057 | |
| epha4a | eph receptor A4a | 0.055 | |
| tnfa | tumor necrosis factor a (TNF superfamily, member 2) | 0.050 | |
| hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.049 | |
| pdlim1 | PDZ and LIM domain 1 (elfin) | 0.047 | |
| sall1a | sal-like 1a (Drosophila) | 0.046 | |
| dag1 | dystroglycan 1 | 0.046 | |
| sox10 | SRY-box containing gene 10 | 0.046 | |
| srf | serum response factor | 0.043 | |
| zgc:171802 | zgc:171802 | 0.043 | |
| fabp11a | fatty acid binding protein 11a | 0.043 | |
| dll4 | delta-like 4 (Drosophila) | 0.043 | |
| gata3 | GATA-binding protein 3 | 0.042 | |
| ptger2a | prostaglandin E receptor 2a (subtype EP2) | 0.042 | |
| tbx2b | T-box 2b | 0.041 | |
| appa | amyloid beta (A4) precursor protein a | 0.041 | |
| sulf2l | sulfatase 2, like | 0.039 | |
| tmem2 | transmembrane protein 2 | 0.039 | |
| ptmaa | prothymosin, alpha a | 0.038 | |
| slit3 | slit (Drosophila) homolog 3 | 0.037 | |
| tnfsf10l | tumor necrosis factor (ligand) superfamily, member 10 like | 0.036 | |
| nrarpa | notch-regulated ankyrin repeat protein a | 0.036 | |
| tie2 | endothelium-specific receptor tyrosine kinase 2 | 0.035 | |
| robo3 | roundabout homolog 3 | 0.034 | |
| ubiad1 | UbiA prenyltransferase domain containing 1 | 0.034 | |
| itgb1a | integrin, beta 1a | 0.034 | |
| foxg1a | forkhead box G1a | 0.033 | |
| itgb1b | integrin, beta 1b | 0.032 | |
| mtp | microsomal triglyceride transfer protein | 0.030 | |
| spry4 | sprouty (Drosophila) homolog 4 | 0.029 | |
| cxcl12b | chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) | 0.029 | |
| unc5b | unc-5 homolog B (C. elegans) | 0.029 | |
| cxcr4b | chemokine (C-X-C motif), receptor 4b | 0.029 | |
| plp1a | proteolipid protein 1a | 0.029 | |
| rtn4b | reticulon 4b | 0.029 | |
| eya1 | eyes absent homolog 1 | 0.028 | |
| foxn1 | forkhead box N1 | 0.028 | |
| wnt10a | wingless-type MMTV integration site family, member 10a | 0.027 | |
| fbn2b | fibrillin 2b | 0.026 | |
| ptp4a1 | protein tyrosine phosphatase type IVA, member 1 | 0.026 | |
| foxn4 | forkhead box N4 | 0.026 | |
| wnt11r | wingless-type MMTV integration site family, member 11, related | 0.026 | |
| stc1l | stanniocalcin 1, like | 0.026 | |
| aldh1a2 | aldehyde dehydrogenase 1 family, member A2 | 0.025 | |
| pitx3 | paired-like homeodomain transcription factor 3 | 0.025 | |
| zdhhc8b | zinc finger, DHHC-type containing 8b | 0.025 | |
| dlb | deltaB | 0.025 | |
| nrg2a | neuregulin 2a | 0.024 | |
| pou3f1 | POU class 3 homeobox 1 | 0.024 | |
| ascl1a | achaete-scute complex-like 1a (Drosophila) | 0.024 | |
| xirp2a | xin actin-binding repeat containing 2a | 0.024 | |
| pkd2 | polycystic kidney disease 2 | 0.024 | |
| boc | brother of CDO | 0.024 | |
| isl1 | islet1 | 0.024 | |
| rtn1a | reticulon 1a | 0.023 | |
| pak2a | p21 (CDKN1A)-activated kinase 2a | 0.023 | |
| sox32 | SRY-box containing gene 32 | 0.023 | |
| col7a1l | collagen type VII alpha 1-like | 0.023 | |
| prox1 | prospero-related homeobox gene 1 | 0.022 | |
| adipoql2 | adiponectin, C1Q and collagen domain containing, like 2 | 0.022 | |
| hoxa13b | homeo box A13b | 0.022 | |
| otpb | orthopedia homolog b | 0.022 | |
| notch1b | notch homolog 1b | 0.021 | |
| zgc:77123 | zgc:77123 | 0.021 | |
| clic4 | chloride intracellular channel 4 | 0.021 | |
| cdh23 | cadherin-like 23 | 0.021 | |
| esrra | estrogen-related receptor alpha | 0.021 | |
| spns2 | spinster homolog 2 (Drosophila) | 0.021 | |
| myod1 | myogenic differentiation 1 | 0.021 | |
| bmp2a | bone morphogenetic protein 2a | 0.020 | |
| irx2a | iroquois homeobox protein 2, a | 0.020 | |
| birc2 | baculoviral IAP repeat-containing 2 | 0.020 | |
| tgfb1a | transforming growth factor, beta 1a | 0.020 | |
| bmp4 | bone morphogenetic protein 4 | 0.020 | |
| aplnra | apelin receptor a | 0.020 | |
| otc | ornithine carbamoyltransferase | 0.020 | |
| adipoql | adiponectin, C1Q and collagen domain containing, like | 0.020 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Col1a1 | collagen, type I, alpha 1 | 0.994 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.991 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.986 | |
| Fbn1 | fibrillin 1 | 0.964 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.961 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.953 | |
| Lox | lysyl oxidase | 0.924 | |
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.920 | |
| Eln | elastin | 0.834 | |
| Kit | kit oncogene | 0.810 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.790 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.638 | |
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.629 | |
| Dll1 | delta-like 1 (Drosophila) | 0.625 | |
| Dll4 | delta-like 4 (Drosophila) | 0.614 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.580 | |
| Trp53 | transformation related protein 53 | 0.575 | |
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.561 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.546 | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.538 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.528 | |
| Lama5 | laminin, alpha 5 | 0.501 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.475 | |
| C1qc | complement component 1, q subcomponent, C chain | 0.469 | |
| Eng | endoglin | 0.459 | |
| Srcin1 | SRC kinase signaling inhibitor 1 | 0.428 | |
| Vasp | vasodilator-stimulated phosphoprotein | 0.412 | |
| Tbx3 | T-box 3 | 0.409 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.403 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.402 | |
| Col5a2 | collagen, type V, alpha 2 | 0.376 | |
| Cdh5 | cadherin 5 | 0.375 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.368 | |
| Stat5b | signal transducer and activator of transcription 5B | 0.364 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.362 | |
| Ar | androgen receptor | 0.356 | |
| Itga3 | integrin alpha 3 | 0.342 | |
| C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.330 | |
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.327 | |
| Col3a1 | collagen, type III, alpha 1 | 0.325 | |
| Pcolce | procollagen C-endopeptidase enhancer protein | 0.317 | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.308 | |
| Pgr | progesterone receptor | 0.306 | |
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.299 | |
| Acan | aggrecan | 0.296 | |
| Foxf1a | forkhead box F1a | 0.295 | |
| Slit3 | slit homolog 3 (Drosophila) | 0.292 | |
| Pax1 | paired box gene 1 | 0.276 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.270 | |
| Kdr | kinase insert domain protein receptor | 0.259 | |
| Tnks1bp1 | tankyrase 1 binding protein 1 | 0.256 | |
| Itga5 | integrin alpha 5 (fibronectin receptor alpha) | 0.255 | |
| Nrp1 | neuropilin 1 | 0.252 | |
| Flt4 | FMS-like tyrosine kinase 4 | 0.252 | |
| Adra2c | adrenergic receptor, alpha 2c | 0.250 | |
| Sox10 | SRY-box containing gene 10 | 0.243 | |
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.239 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.235 | |
| Enah | enabled homolog (Drosophila) | 0.235 | |
| Pten | phosphatase and tensin homolog | 0.235 | |
| C1qb | complement component 1, q subcomponent, beta polypeptide | 0.233 | |
| Psen1 | presenilin 1 | 0.232 | |
| Meox2 | mesenchyme homeobox 2 | 0.231 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.230 | |
| Ptprn | protein tyrosine phosphatase, receptor type, N | 0.228 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.226 | |
| Cldn5 | claudin 5 | 0.222 | |
| Pax3 | paired box gene 3 | 0.220 | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.220 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.219 | |
| Fstl1 | follistatin-like 1 | 0.219 | |
| Egfr | epidermal growth factor receptor | 0.218 | |
| Prl8a2 | prolactin family 8, subfamily a, member 2 | 0.218 | |
| Sox7 | SRY-box containing gene 7 | 0.216 | |
| Col6a2 | collagen, type VI, alpha 2 | 0.215 | |
| Sstr5 | somatostatin receptor 5 | 0.214 | |
| Flt1 | FMS-like tyrosine kinase 1 | 0.210 | |
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.209 | |
| Pdgfb | platelet derived growth factor, B polypeptide | 0.208 | |
| Loxl1 | lysyl oxidase-like 1 | 0.207 | |
| Tgfa | transforming growth factor alpha | 0.205 | |
| Gja5 | gap junction protein, alpha 5 | 0.204 | |
| Plcg1 | phospholipase C, gamma 1 | 0.202 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.199 | |
| Des | desmin | 0.199 | |
| Robo1 | roundabout homolog 1 (Drosophila) | 0.198 | |
| Ptprn2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.196 | |
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.196 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.194 | |
| Col12a1 | collagen, type XII, alpha 1 | 0.193 | |
| Kl | klotho | 0.189 | |
| Prlr | prolactin receptor | 0.187 | |
| Amhr2 | anti-Mullerian hormone type 2 receptor | 0.186 | |
| Hoxc9 | homeobox C9 | 0.185 | |
| Suds3 | suppressor of defective silencing 3 homolog (S. cerevisiae) | 0.185 | |
| Col4a1 | collagen, type IV, alpha 1 | 0.184 | |
| C3ar1 | complement component 3a receptor 1 | 0.177 | |
| Itgb3 | integrin beta 3 | 0.174 | |
| F2r | coagulation factor II (thrombin) receptor | 0.171 | |
| Smad1 | MAD homolog 1 (Drosophila) | 0.170 |