The network for 'myoblast fusion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

myoblast fusion

A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.

Homo sapiens
Name Description Probability Func Analog Organism
GRB2 growth factor receptor-bound protein 2 0.999
CREBBP CREB binding protein 0.986
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.901
EGFR epidermal growth factor receptor 0.891
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.855
PGK1 phosphoglycerate kinase 1 0.814
IL4R interleukin 4 receptor 0.792
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.749
ALDOA aldolase A, fructose-bisphosphate 0.747
PTK2 PTK2 protein tyrosine kinase 2 0.740
LIMS1 LIM and senescent cell antigen-like domains 1 0.738
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.665
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.632
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.624
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.612
IQGAP1 IQ motif containing GTPase activating protein 1 0.594
AR androgen receptor 0.570
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.569
NCOA3 nuclear receptor coactivator 3 0.557
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.528
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.516
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.436
KAT2B K(lysine) acetyltransferase 2B 0.435
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.433
PGAM1 phosphoglycerate mutase 1 (brain) 0.427
LDHA lactate dehydrogenase A 0.426
ACTB actin, beta 0.419
MYL9 myosin, light chain 9, regulatory 0.413
DPP4 dipeptidyl-peptidase 4 0.409
VAV1 vav 1 guanine nucleotide exchange factor 0.402
WIPF1 WAS/WASL interacting protein family, member 1 0.398
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.391
GPI glucose-6-phosphate isomerase 0.359
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.355
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.315
STK10 serine/threonine kinase 10 0.315
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.314
LRRK2 leucine-rich repeat kinase 2 0.306
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.305
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.305
ENO1 enolase 1, (alpha) 0.303
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.293
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.292
NLRC4 NLR family, CARD domain containing 4 0.289
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.261
GRB10 growth factor receptor-bound protein 10 0.249
IL2RG interleukin 2 receptor, gamma 0.240
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.236
CXCL11 chemokine (C-X-C motif) ligand 11 0.227
IRS1 insulin receptor substrate 1 0.225
LZTS2 leucine zipper, putative tumor suppressor 2 0.212
HIPK2 homeodomain interacting protein kinase 2 0.205
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.203
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.201
SH3RF1 SH3 domain containing ring finger 1 0.199
SH3KBP1 SH3-domain kinase binding protein 1 0.199
HDAC4 histone deacetylase 4 0.196
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.195
BCAR1 breast cancer anti-estrogen resistance 1 0.190
RPTOR regulatory associated protein of MTOR, complex 1 0.190
NCK1 NCK adaptor protein 1 0.185
GAB1 GRB2-associated binding protein 1 0.184
IL4 interleukin 4 0.179
COASY CoA synthase 0.179
NCOA6 nuclear receptor coactivator 6 0.176
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.158
HCK hemopoietic cell kinase 0.158
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.151
MAP2K3 mitogen-activated protein kinase kinase 3 0.149
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.145
EP300 E1A binding protein p300 0.144
MED31 mediator complex subunit 31 0.139
CTTN cortactin 0.137
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.135
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.132
SIRT1 sirtuin 1 0.130
IRS2 insulin receptor substrate 2 0.128
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.127
RICTOR RPTOR independent companion of MTOR, complex 2 0.124
ANKFY1 ankyrin repeat and FYVE domain containing 1 0.124
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.120
CREB1 cAMP responsive element binding protein 1 0.119
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.119
NCF2 neutrophil cytosolic factor 2 0.118
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 0.118
FLNA filamin A, alpha 0.115
RUNX1 runt-related transcription factor 1 0.111
TNS1 tensin 1 0.111
ZYX zyxin 0.110
TPI1 triosephosphate isomerase 1 0.101
HDAC9 histone deacetylase 9 0.101
INSR insulin receptor 0.100
ABI2 abl-interactor 2 0.098
FOXO3 forkhead box O3 0.094
SMAD3 SMAD family member 3 0.092
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.091
JAM3 junctional adhesion molecule 3 0.090
NCOA1 nuclear receptor coactivator 1 0.089
HOXA1 homeobox A1 0.087
TCF4 transcription factor 4 0.086
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
myod1 myogenic differentiation 1 0.918
mef2ca myocyte enhancer factor 2ca 0.844
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.811
mef2d myocyte enhancer factor 2d 0.679
myog myogenin 0.485
jam2a junctional adhesion molecule 2a 0.436
tpm4 tropomyosin 4 0.370
gmfg glia maturation factor, gamma 0.206
kirrel3l kin of IRRE like 3 like 0.199
jam3b junctional adhesion molecule 3b 0.198
dock1 dedicator of cytokinesis 1 0.167
wt1b wilms tumor 1b 0.165
desma desmin a 0.153
met met proto-oncogene (hepatocyte growth factor receptor) 0.146
vegfab vascular endothelial growth factor Ab 0.138
meox1 mesenchyme homeobox 1 0.131
akt2 v-akt murine thymoma viral oncogene homolog 2 0.124
dcc deleted in colorectal carcinoma 0.116
wt1a wilms tumor 1a 0.113
si:dkey-27i16.2 si:dkey-27i16.2 0.110
gata6 GATA-binding protein 6 0.109
ldb2a LIM-domain binding factor 2a 0.107
podxl podocalyxin-like 0.103
colec11 collectin sub-family member 11 0.100
crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.099
lsr lipolysis stimulated lipoprotein receptor 0.097
mef2a myocyte enhancer factor 2a 0.096
zbtb4 zinc finger and BTB domain containing 4 0.094
glcci1 glucocorticoid induced transcript 1 0.093
myf5 myogenic factor 5 0.091
rapsn receptor-associated protein of the synapse, 43kD 0.090
nphs1l nephrosis 1, congenital, Finnish type (nephrin)-like 0.085
etv2 ets variant gene 2 0.083
vmhc ventricular myosin heavy chain 0.082
smyd1b SET and MYND domain containing 1b 0.077
lyz lysozyme 0.073
hsp90a.1 heat shock protein 90-alpha 1 0.068
dock5 dedicator of cytokinesis 5 0.066
cyt1 type I cytokeratin, enveloping layer 0.063
vdra vitamin D receptor a 0.060
cdh1 cadherin 1, epithelial 0.056
myf6 myogenic factor 6 0.055
mmp9 matrix metalloproteinase 9 0.053
caspa caspase a 0.052
adipor1b adiponectin receptor 1b 0.052
atp1b2a ATPase, Na+/K+ transporting, beta 2a polypeptide 0.050
frmd6 FERM domain containing 6 0.047
pkm2a pyruvate kinase, muscle, a 0.046
ldb1a LIM-domain binding factor 1a 0.045
foxn1 forkhead box N1 0.044
vegfaa vascular endothelial growth factor Aa 0.044
ldb3a LIM-domain binding factor 3a 0.043
osr1 odd-skipped related 1 (Drosophila) 0.042
wtip Wilms tumor 1 interacting protein 0.042
tcf12 transcription factor 12 0.042
dhrs3a dehydrogenase/reductase (SDR family) member 3a 0.042
unc5c unc-5 homolog C (C. elegans) 0.039
ctnna catenin (cadherin-associated protein), alpha 0.039
vgll2b vestigial like 2b 0.038
unc45b unc-45 homolog B (C. elegans) 0.038
coro1a coronin, actin binding protein, 1A 0.038
rbfox1l RNA binding protein, fox-1 homolog (C. elegans) 1-like 0.037
zgc:112257 zgc:112257 0.036
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.035
zgc:101523 zgc:101523 0.035
LOC566969 similar to MOX-2 protein 0.034
mpll myeloproliferative leukemia virus oncogene, like 0.034
flncb filamin C, gamma b (actin binding protein 280) 0.033
irx5a iroquois homeobox protein 5a 0.032
zgc:112211 zgc:112211 0.032
mybpc2b myosin binding protein C, fast type b 0.031
bmp2k BMP2 inducible kinase 0.031
hoxa9b homeo box A9b 0.030
hoxb5a homeo box B5a 0.029
rest RE1-silencing transcription factor 0.028
myca myelocytomatosis oncogene a 0.027
sh3gl1b SH3-domain GRB2-like 1b 0.026
zgc:91930 zgc:91930 0.026
crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.026
gpia glucose phosphate isomerase a 0.026
sept2 septin 2 0.026
vax2 ventral anterior homeobox 2 0.025
atp1a2a ATPase, Na+/K+ transporting, alpha 2a polypeptide 0.025
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.025
plce1 phospholipase C, epsilon 1 0.025
arhgef1 rho guanine nucleotide exchange factor (GEF) 1 0.025
emp2 epithelial membrane protein 2 0.024
sema3fa semaphorin 3fa 0.023
LOC557722 similar to transient receptor potential cation channel, subfamily M, member 5 0.023
llgl2 lethal giant larvae homolog 2 (Drosophila) 0.023
zgc:136894 zgc:136894 0.023
nr1h5 nuclear receptor subfamily 1, group H, member 5 0.023
si:dkey-233h2.3 si:dkey-233h2.3 0.022
pgm1 phosphoglucomutase 1 0.022
ryr1b ryanodine receptor 1b (skeletal) 0.022
myhc4 myosin heavy chain 4 0.022
tnfsf18 tumor necrosis factor (ligand) superfamily, member 18 0.022
zgc:112180 zgc:112180 0.021
eno3 enolase 3, (beta, muscle) 0.021
pabpc4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.021
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Vrp1 Verprolin 1 1.000
hbs hibris 1.000
sns sticks and stones 1.000
rols rolling pebbles 1.000
mbc myoblast city 0.999
Rac2 CG8556 gene product from transcript CG8556-RA 0.999
Pglym78 Phosphoglyceromutase 0.999
Pax Paxillin 0.999
rst roughest 0.999
Arf51F ADP ribosylation factor 51F 0.998
blow blown fuse 0.998
Mp20 Muscle protein 20 0.992
pfk piefke 0.991
sls sallimus 0.990
S6k RPS6-p70-protein kinase 0.989
Tpi Triose phosphate isomerase 0.988
WASp CG1520 gene product from transcript CG1520-RA 0.986
PyK Pyruvate kinase 0.985
kirre kin of irre 0.982
Rac1 CG2248 gene product from transcript CG2248-RA 0.977
Mef2 Myocyte enhancer factor 2 0.976
Thor CG8846 gene product from transcript CG8846-RA 0.958
htl heartless 0.946
Arf79F ADP ribosylation factor 79F 0.933
Hem HEM-protein 0.885
mib2 mind bomb 2 0.863
foxo forkhead box, sub-group O 0.845
Rho1 CG8416 gene product from transcript CG8416-RB 0.825
lbe ladybird early 0.811
siz schizo 0.803
Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1 0.797
Sdc Syndecan 0.783
Alk CG8250 gene product from transcript CG8250-RA 0.780
sing singles bar 0.774
lmd lame duck 0.765
Mlp84B Muscle LIM protein at 84B 0.749
ImpL3 Ecdysone-inducible gene L3 0.743
vav CG7893 gene product from transcript CG7893-RB 0.740
aop anterior open 0.720
zfh1 Zn finger homeodomain 1 0.682
slou slouch 0.675
Arp66B Actin-related protein 66B 0.673
p120ctn Adherens junction protein p120 0.626
LamC Lamin C 0.620
kon kon-tiki 0.556
Rala Ras-related protein 0.554
ptc patched 0.507
bib big brain 0.488
InR Insulin-like receptor 0.403
Parp Poly-(ADP-ribose) polymerase 0.387
Abi Abelson interacting protein 0.340
nau nautilus 0.296
Grip Glutamate receptor binding protein 0.288
Pgk Phosphoglycerate kinase 0.282
Sra-1 specifically Rac1-associated protein 1 0.263
Pak3 CG14895 gene product from transcript CG14895-RA 0.253
Him Holes in muscle 0.234
imd immune deficiency 0.225
Akt1 CG4006 gene product from transcript CG4006-RA 0.220
bsk basket 0.185
byn brachyenteron 0.182
pan pangolin 0.181
Kr-h1 Kruppel homolog 1 0.169
sd scalloped 0.152
sr stripe 0.150
mys myospheroid 0.148
eya eyes absent 0.148
C3G CG42328 gene product from transcript CG42328-RC 0.136
Ras85D Ras oncogene at 85D 0.135
tin tinman 0.129
insc inscuteable 0.127
CG1021 CG1021 gene product from transcript CG1021-RE 0.124
RanBPM Ran-binding protein M 0.123
drk downstream of receptor kinase 0.121
Gs1 Glutamine synthetase 1 0.114
otk off-track 0.113
Atg1 Autophagy-specific gene 1 0.105
Dcr-2 Dicer-2 0.104
org-1 optomotor-blind-related-gene-1 0.103
dock dreadlocks 0.101
Lrt Leucine-rich tendon-specific protein 0.095
vimar visceral mesodermal armadillo-repeats 0.093
Taf4 TBP-associated factor 4 0.091
scb scab 0.089
jeb jelly belly 0.086
Myd88 CG2078 gene product from transcript CG2078-RA 0.084
X11L CG5675 gene product from transcript CG5675-RB 0.083
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.082
side sidestep 0.080
CG32528 CG32528 gene product from transcript CG32528-RA 0.076
tio tiptop 0.071
pcs parcas 0.066
eve even skipped 0.065
Eno Enolase 0.062
bin biniou 0.061
scny scrawny 0.060
Atx2 Ataxin-2 0.059
Gyc76C Guanylyl cyclase at 76C 0.059
key kenny 0.058
Tsp Thrombospondin 0.058
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Casp1 caspase 1 0.060
Emp1 epithelial membrane protein 1 0.043
Pgk1 phosphoglycerate kinase 1 0.040
Syngr2 synaptogyrin 2 0.037
Ptbp1 polypyrimidine tract binding protein 1 0.036
Myo1b myosin Ib 0.033
Tpm4 tropomyosin 4 0.033
Msn moesin 0.032
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.030
Ampd1 adenosine monophosphate deaminase 1 (isoform M) 0.030
Lbr lamin B receptor 0.028
Tcf12 transcription factor 12 0.028
Myo1c myosin IC 0.025
Ptprc protein tyrosine phosphatase, receptor type, C 0.025
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.025
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.024
Tgfbr2 transforming growth factor, beta receptor II 0.024
Smad1 SMAD family member 1 0.024
Il5 interleukin 5 0.023
Ms4a11 membrane-spanning 4-domains, subfamily A, member 11 0.022
Skap2 src kinase associated phosphoprotein 2 0.021
Cast calpastatin 0.021
Tpi1 triosephosphate isomerase 1 0.020
Txnrd1 thioredoxin reductase 1 0.020
Arl5a ADP-ribosylation factor-like 5A 0.020
Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) 0.019
Ccnd3 cyclin D3 0.019
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.019
Mdh1 malate dehydrogenase 1, NAD (soluble) 0.019
Myh9 myosin, heavy chain 9, non-muscle 0.019
Cxcl9 chemokine (C-X-C motif) ligand 9 0.019
Plek pleckstrin 0.019
Cald1 caldesmon 1 0.018
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.018
Acvr1 activin A receptor, type I 0.017
Flnb filamin, beta 0.017
Eef2 eukaryotic translation elongation factor 2 0.017
Cdk2 cyclin dependent kinase 2 0.017
Lamc1 laminin, gamma 1 0.017
Adam10 ADAM metallopeptidase domain 10 0.017
Mobkl1b MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.017
Actn4 actinin alpha 4 0.017
Col4a1 collagen, type IV, alpha 1 0.017
Irs1 insulin receptor substrate 1 0.016
Nat1 N-acetyltransferase 1 0.016
Adam17 ADAM metallopeptidase domain 17 0.016
Clic4 chloride intracellular channel 4 0.016
Arf6 ADP-ribosylation factor 6 0.016
Stk17b serine/threonine kinase 17b 0.016
Scarb1 scavenger receptor class B, member 1 0.016
Lin7c lin-7 homolog C (C. elegans) 0.016
S1pr2 sphingosine-1-phosphate receptor 2 0.015
Galnt1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) 0.015
Myh3 myosin, heavy chain 3, skeletal muscle, embryonic 0.015
Cpa1 carboxypeptidase A1 0.015
Shisa5 shisa homolog 5 (Xenopus laevis) 0.015
Itga6 integrin, alpha 6 0.015
Fusip1 FUS interacting protein (serine-arginine rich) 1 0.015
Id2 inhibitor of DNA binding 2 0.015
Ccl20 chemokine (C-C motif) ligand 20 0.015
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.015
Dnajc14 DnaJ (Hsp40) homolog, subfamily C, member 14 0.015
Itgal integrin, alpha L 0.015
Efhd2 EF-hand domain family, member D2 0.015
Itgb2 integrin, beta 2 0.014
Iqgap1 IQ motif containing GTPase activating protein 1 0.014
Prkch protein kinase C, eta 0.014
Hbg1 hemoglobin, gamma A 0.014
Mypn myopalladin 0.014
Cngb1 cyclic nucleotide gated channel beta 1 0.014
Stat6 signal transducer and activator of transcription 6 0.014
Cd48 Cd48 molecule 0.014
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.014
Casp8 caspase 8 0.014
Cd38 CD38 molecule 0.013
Mprip myosin phosphatase Rho interacting protein 0.013
Anxa1 annexin A1 0.013
Glipr1 GLI pathogenesis-related 1 0.013
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.013
Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.013
Snn stannin 0.013
Fam198b family with sequence similarity 198, member B 0.013
Cav3 caveolin 3 0.013
Elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.013
Jak2 Janus kinase 2 0.013
Klk1c10 T-kininogenase 0.013
Mylpf myosin light chain, phosphorylatable, fast skeletal muscle 0.013
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.013
Fbln5 fibulin 5 0.013
Evi2a ecotropic viral integration site 2A 0.013
Cxcl11 chemokine (C-X-C motif) ligand 11 0.013
Arih1 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) 0.013
Gbp2 guanylate binding protein 2 0.013
Arhgap1 Rho GTPase activating protein 1 0.013
Ahnak AHNAK nucleoprotein 0.013
Nras neuroblastoma ras oncogene 0.012
Smpx small muscle protein, X-linked 0.012
Rhoa ras homolog gene family, member A 0.012
Myl1 myosin, light chain 1 0.012
Lamb2 laminin, beta 2 0.012
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism