The network for 'regulation of chemokine production' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of chemokine production

Any process that modulates the frequency, rate, or extent of chemokine production.

Homo sapiens
Name Description Probability Func Analog Organism
MYD88 myeloid differentiation primary response gene (88) 0.997
IL1R1 interleukin 1 receptor, type I 0.997
C1QA complement component 1, q subcomponent, A chain 0.973
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.957
TLR4 toll-like receptor 4 0.904
ABI2 abl-interactor 2 0.617
VEGFA vascular endothelial growth factor A 0.609
HDAC2 histone deacetylase 2 0.587
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.569
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.527
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.396
C1QC complement component 1, q subcomponent, C chain 0.395
NRP1 neuropilin 1 0.356
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.309
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.302
TICAM2 toll-like receptor adaptor molecule 2 0.277
IL4R interleukin 4 receptor 0.260
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.236
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.233
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.230
TMEM173 transmembrane protein 173 0.228
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.222
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.222
IL8 interleukin 8 0.220
BIRC3 baculoviral IAP repeat containing 3 0.212
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.209
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.191
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.177
GAB1 GRB2-associated binding protein 1 0.175
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.173
IL6 interleukin 6 (interferon, beta 2) 0.173
KLF6 Kruppel-like factor 6 0.170
COTL1 coactosin-like 1 (Dictyostelium) 0.166
IL4 interleukin 4 0.161
SNX9 sorting nexin 9 0.154
APOE apolipoprotein E 0.150
IL1RAP interleukin 1 receptor accessory protein 0.136
C1QB complement component 1, q subcomponent, B chain 0.127
RBBP4 retinoblastoma binding protein 4 0.121
PTPRB protein tyrosine phosphatase, receptor type, B 0.121
NLRC4 NLR family, CARD domain containing 4 0.113
MEFV Mediterranean fever 0.113
CXCL2 chemokine (C-X-C motif) ligand 2 0.112
GATA2 GATA binding protein 2 0.110
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.103
FZD1 frizzled homolog 1 (Drosophila) 0.100
PGF placental growth factor 0.096
DLG1 discs, large homolog 1 (Drosophila) 0.084
LDLR low density lipoprotein receptor 0.084
LAT linker for activation of T cells 0.083
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.078
KLF4 Kruppel-like factor 4 (gut) 0.073
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.072
CTBP1 C-terminal binding protein 1 0.069
CFH complement factor H 0.068
TAL1 T-cell acute lymphocytic leukemia 1 0.065
IGFBP3 insulin-like growth factor binding protein 3 0.063
SH3D19 SH3 domain containing 19 0.055
DUSP1 dual specificity phosphatase 1 0.054
IL1R2 interleukin 1 receptor, type II 0.053
IRAK4 interleukin-1 receptor-associated kinase 4 0.052
CXCL3 chemokine (C-X-C motif) ligand 3 0.051
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.050
CDH5 cadherin 5, type 2 (vascular endothelium) 0.049
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.048
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.048
JUN jun proto-oncogene 0.048
ASRGL1 asparaginase like 1 0.047
PDGFA platelet-derived growth factor alpha polypeptide 0.046
TLR2 toll-like receptor 2 0.046
EHMT2 euchromatic histone-lysine N-methyltransferase 2 0.043
IRAK2 interleukin-1 receptor-associated kinase 2 0.042
PDIA3 protein disulfide isomerase family A, member 3 0.042
TICAM1 toll-like receptor adaptor molecule 1 0.042
IL6R interleukin 6 receptor 0.041
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.041
SOS1 son of sevenless homolog 1 (Drosophila) 0.041
KITLG KIT ligand 0.039
CFI complement factor I 0.039
STAB1 stabilin 1 0.038
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.038
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.037
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.037
IRF8 interferon regulatory factor 8 0.035
LY96 lymphocyte antigen 96 0.035
PIAS2 protein inhibitor of activated STAT, 2 0.035
IL2RG interleukin 2 receptor, gamma 0.034
SNX33 sorting nexin 33 0.034
NLRP3 NLR family, pyrin domain containing 3 0.034
TXN thioredoxin 0.033
PYCARD PYD and CARD domain containing 0.033
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.033
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.033
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.032
VSIG4 V-set and immunoglobulin domain containing 4 0.032
MPO myeloperoxidase 0.032
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.030
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 0.030
CCL20 chemokine (C-C motif) ligand 20 0.030
MTA1 metastasis associated 1 0.029
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Myd88 myeloid differentiation primary response gene 88 0.997
Il1rn interleukin 1 receptor antagonist 0.966
Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) 0.966
Casp1 caspase 1 0.963
Cxcl2 chemokine (C-X-C motif) ligand 2 0.942
Il1rl1 interleukin 1 receptor-like 1 0.913
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.906
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.887
Mmp8 matrix metallopeptidase 8 0.833
Il1r1 interleukin 1 receptor, type I 0.814
Il1b interleukin 1 beta 0.808
Nlrp3 NLR family, pyrin domain containing 3 0.753
Cd44 CD44 antigen 0.738
Ccr2 chemokine (C-C motif) receptor 2 0.707
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.700
Il6 interleukin 6 0.666
Selp selectin, platelet 0.647
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.613
Clec4d C-type lectin domain family 4, member d 0.575
Mmp9 matrix metallopeptidase 9 0.535
Cd14 CD14 antigen 0.520
Clec4e C-type lectin domain family 4, member e 0.500
Chi3l3 chitinase 3-like 3 0.480
Fpr2 formyl peptide receptor 2 0.454
Ccl2 chemokine (C-C motif) ligand 2 0.450
Tnf tumor necrosis factor 0.442
Slpi secretory leukocyte peptidase inhibitor 0.439
Il10 interleukin 10 0.378
Cxcr2 chemokine (C-X-C motif) receptor 2 0.376
Ccl7 chemokine (C-C motif) ligand 7 0.364
Lyz2 lysozyme 2 0.361
Mefv Mediterranean fever 0.361
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.354
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.343
Irg1 immunoresponsive gene 1 0.341
Cd86 CD86 antigen 0.331
Il18rap interleukin 18 receptor accessory protein 0.331
C5ar1 complement component 5a receptor 1 0.320
Irak4 interleukin-1 receptor-associated kinase 4 0.315
Tlr4 toll-like receptor 4 0.315
Il6st interleukin 6 signal transducer 0.294
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.282
Chi3l1 chitinase 3-like 1 0.277
C3ar1 complement component 3a receptor 1 0.271
Msr1 macrophage scavenger receptor 1 0.263
Ch25h cholesterol 25-hydroxylase 0.254
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.233
Btk Bruton agammaglobulinemia tyrosine kinase 0.228
Fpr1 formyl peptide receptor 1 0.226
S100a9 S100 calcium binding protein A9 (calgranulin B) 0.222
Cd33 CD33 antigen 0.221
Gata1 GATA binding protein 1 0.220
Klra2 killer cell lectin-like receptor, subfamily A, member 2 0.206
Rel reticuloendotheliosis oncogene 0.205
Ccl4 chemokine (C-C motif) ligand 4 0.204
Ccl3 chemokine (C-C motif) ligand 3 0.200
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.172
Ticam1 toll-like receptor adaptor molecule 1 0.169
Il2rg interleukin 2 receptor, gamma chain 0.165
Cd300lf CD300 antigen like family member F 0.160
Stat6 signal transducer and activator of transcription 6 0.158
Ngp neutrophilic granule protein 0.154
Ifnar1 interferon (alpha and beta) receptor 1 0.143
Gpr97 G protein-coupled receptor 97 0.139
Trem3 triggering receptor expressed on myeloid cells 3 0.137
Niacr1 niacin receptor 1 0.135
Slfn4 schlafen 4 0.133
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.130
Birc3 baculoviral IAP repeat-containing 3 0.130
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.125
Il1a interleukin 1 alpha 0.120
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.120
Csf1 colony stimulating factor 1 (macrophage) 0.118
1100001G20Rik RIKEN cDNA 1100001G20 gene 0.115
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.111
F2rl2 coagulation factor II (thrombin) receptor-like 2 0.111
Stat3 signal transducer and activator of transcription 3 0.109
Il1r2 interleukin 1 receptor, type II 0.108
Slfn1 schlafen 1 0.107
Asprv1 aspartic peptidase, retroviral-like 1 0.095
Il1f9 interleukin 1 family, member 9 0.093
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.092
Fcgr4 Fc receptor, IgG, low affinity IV 0.092
Cd80 CD80 antigen 0.091
Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.090
Unc93b1 unc-93 homolog B1 (C. elegans) 0.089
Cxcl5 chemokine (C-X-C motif) ligand 5 0.088
Il18r1 interleukin 18 receptor 1 0.082
Mpo myeloperoxidase 0.082
Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 0.082
Lcn2 lipocalin 2 0.080
Cxcl1 chemokine (C-X-C motif) ligand 1 0.080
Saa3 serum amyloid A 3 0.077
Runx1 runt related transcription factor 1 0.077
Icos inducible T-cell co-stimulator 0.076
Tal1 T-cell acute lymphocytic leukemia 1 0.076
Slamf8 SLAM family member 8 0.074
Il4ra interleukin 4 receptor, alpha 0.074
Gfi1b growth factor independent 1B 0.073
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.073
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Rattus norvegicus
Name Description Probability Func Analog Organism
Rps5 ribosomal protein S5 0.017
Rplp0 ribosomal protein, large, P0 0.013
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism