The network for 'hair follicle development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hair follicle development

The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.

Mus musculus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 1.000
Foxc1 forkhead box C1 0.999
Bmp4 bone morphogenetic protein 4 0.998
Ctnnb1 catenin (cadherin associated protein), beta 1 0.998
Gli3 GLI-Kruppel family member GLI3 0.996
Krt17 keratin 17 0.985
Egfr epidermal growth factor receptor 0.983
Foxn1 forkhead box N1 0.980
Notch2 Notch gene homolog 2 (Drosophila) 0.973
Bcl2 B-cell leukemia/lymphoma 2 0.971
Pax2 paired box gene 2 0.966
Bmpr1a bone morphogenetic protein receptor, type 1A 0.965
Wnt3a wingless-related MMTV integration site 3A 0.962
Hoxd13 homeobox D13 0.958
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.956
Pten phosphatase and tensin homolog 0.947
Hr hairless 0.946
Tgfa transforming growth factor alpha 0.944
Shh sonic hedgehog 0.939
Msx2 homeobox, msh-like 2 0.932
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.922
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.914
Csf1 colony stimulating factor 1 (macrophage) 0.913
Smad3 MAD homolog 3 (Drosophila) 0.912
Wnt4 wingless-related MMTV integration site 4 0.904
Col1a1 collagen, type I, alpha 1 0.892
Lmx1b LIM homeobox transcription factor 1 beta 0.891
Krt14 keratin 14 0.890
Smad6 MAD homolog 6 (Drosophila) 0.885
Vangl2 vang-like 2 (van gogh, Drosophila) 0.881
Fgfr1 fibroblast growth factor receptor 1 0.879
Psen1 presenilin 1 0.874
Ptk7 PTK7 protein tyrosine kinase 7 0.873
Otx2 orthodenticle homolog 2 (Drosophila) 0.860
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.849
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.848
Emx1 empty spiracles homolog 1 (Drosophila) 0.831
Pax3 paired box gene 3 0.822
Vegfa vascular endothelial growth factor A 0.812
Hes1 hairy and enhancer of split 1 (Drosophila) 0.786
Pthlh parathyroid hormone-like peptide 0.765
Ret ret proto-oncogene 0.761
Rxra retinoid X receptor alpha 0.743
Meox2 mesenchyme homeobox 2 0.743
Smad4 MAD homolog 4 (Drosophila) 0.742
Eda ectodysplasin-A 0.740
Cav1 caveolin 1, caveolae protein 0.738
Pax6 paired box gene 6 0.738
Axin1 axin 1 0.730
Alx4 aristaless-like homeobox 4 0.726
Hif1a hypoxia inducible factor 1, alpha subunit 0.723
Wnt7b wingless-related MMTV integration site 7B 0.696
Fgf8 fibroblast growth factor 8 0.695
Nog noggin 0.688
Tgfbr2 transforming growth factor, beta receptor II 0.686
Sox2 SRY-box containing gene 2 0.667
Fst follistatin 0.663
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.654
Hoxd11 homeobox D11 0.635
Pitx2 paired-like homeodomain transcription factor 2 0.608
Tgfb1 transforming growth factor, beta 1 0.600
Npr3 natriuretic peptide receptor 3 0.591
Gdf11 growth differentiation factor 11 0.584
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.577
Atoh7 atonal homolog 7 (Drosophila) 0.575
Fgfr3 fibroblast growth factor receptor 3 0.568
Krt35 keratin 35 0.567
Sox10 SRY-box containing gene 10 0.556
Msx1 homeobox, msh-like 1 0.549
Twist2 twist homolog 2 (Drosophila) 0.546
Tcfap2a transcription factor AP-2, alpha 0.544
Cldn3 claudin 3 0.543
Lef1 lymphoid enhancer binding factor 1 0.538
Bmp7 bone morphogenetic protein 7 0.537
Gas1 growth arrest specific 1 0.530
Pax8 paired box gene 8 0.524
Jag1 jagged 1 0.521
Tcf21 transcription factor 21 0.515
Wnt7a wingless-related MMTV integration site 7A 0.512
Gdnf glial cell line derived neurotrophic factor 0.508
Apaf1 apoptotic peptidase activating factor 1 0.507
Gjb4 gap junction protein, beta 4 0.504
Isl1 ISL1 transcription factor, LIM/homeodomain 0.504
Nos2 nitric oxide synthase 2, inducible 0.503
Dlx5 distal-less homeobox 5 0.502
Fgf23 fibroblast growth factor 23 0.497
Tcfap2c transcription factor AP-2, gamma 0.493
Pkp1 plakophilin 1 0.491
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.490
Notch1 Notch gene homolog 1 (Drosophila) 0.484
Krt86 keratin 86 0.479
Prrx2 paired related homeobox 2 0.479
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.476
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.471
Lep leptin 0.470
Rarg retinoic acid receptor, gamma 0.469
Krt33b keratin 33B 0.458
Tgfb2 transforming growth factor, beta 2 0.455
Lta lymphotoxin A 0.454
Acvr1 activin A receptor, type 1 0.454
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
KRT15 keratin 15 0.716
PKP1 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) 0.599
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.592
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.388
TP63 tumor protein p63 0.311
KRT17 keratin 17 0.257
KDM1A lysine (K)-specific demethylase 1A 0.235
KRT19 keratin 19 0.230
DSG2 desmoglein 2 0.204
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.180
KRT18 keratin 18 0.172
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.159
GSK3B glycogen synthase kinase 3 beta 0.151
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.139
FGF10 fibroblast growth factor 10 0.127
C19orf50 chromosome 19 open reading frame 50 0.119
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.117
LMO4 LIM domain only 4 0.108
BCL2L1 BCL2-like 1 0.097
FKBP1A FK506 binding protein 1A, 12kDa 0.082
KRT6C keratin 6C 0.082
KRT5 keratin 5 0.071
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.070
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.068
PDZD11 PDZ domain containing 11 0.055
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 0.053
JUP junction plakoglobin 0.044
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.044
TRIM29 tripartite motif containing 29 0.039
KRT6B keratin 6B 0.038
ARRB1 arrestin, beta 1 0.037
FGF1 fibroblast growth factor 1 (acidic) 0.035
JAG1 jagged 1 0.034
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.033
FLNB filamin B, beta 0.032
SPEN spen homolog, transcriptional regulator (Drosophila) 0.031
APC adenomatous polyposis coli 0.028
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.027
SMAD2 SMAD family member 2 0.027
TP53 tumor protein p53 0.026
FGFR1 fibroblast growth factor receptor 1 0.026
LRP6 low density lipoprotein receptor-related protein 6 0.026
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.025
KRT6A keratin 6A 0.025
CIB1 calcium and integrin binding 1 (calmyrin) 0.022
PPL periplakin 0.021
EP300 E1A binding protein p300 0.021
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.021
UBXN2A UBX domain protein 2A 0.020
FGF18 fibroblast growth factor 18 0.020
ERBB2IP erbb2 interacting protein 0.020
INHBA inhibin, beta A 0.020
YY1 YY1 transcription factor 0.019
KRT34 keratin 34 0.019
FHL2 four and a half LIM domains 2 0.018
MSX1 msh homeobox 1 0.018
GLIS2 GLIS family zinc finger 2 0.018
RLIM ring finger protein, LIM domain interacting 0.018
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.017
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.017
CTNND1 catenin (cadherin-associated protein), delta 1 0.017
FST follistatin 0.017
COL7A1 collagen, type VII, alpha 1 0.017
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.016
TGFB3 transforming growth factor, beta 3 0.016
ATXN3 ataxin 3 0.015
AR androgen receptor 0.015
NUCB1 nucleobindin 1 0.015
SFRP1 secreted frizzled-related protein 1 0.015
NOTCH3 notch 3 0.015
FGFR3 fibroblast growth factor receptor 3 0.015
ALOX12 arachidonate 12-lipoxygenase 0.014
BCAM basal cell adhesion molecule (Lutheran blood group) 0.014
ACVR2B activin A receptor, type IIB 0.014
ENG endoglin 0.014
BTRC beta-transducin repeat containing 0.014
RCOR1 REST corepressor 1 0.013
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.013
NCOR2 nuclear receptor corepressor 2 0.013
MAML1 mastermind-like 1 (Drosophila) 0.013
STK3 serine/threonine kinase 3 0.013
KRT75 keratin 75 0.013
MTA3 metastasis associated 1 family, member 3 0.013
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.012
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.012
KRT81 keratin 81 0.012
STMN2 stathmin-like 2 0.012
ATXN1L ataxin 1-like 0.012
EDAR ectodysplasin A receptor 0.012
BMP2 bone morphogenetic protein 2 0.012
CXCR5 chemokine (C-X-C motif) receptor 5 0.012
FGF7 fibroblast growth factor 7 0.012
PKP4 plakophilin 4 0.012
DSG3 desmoglein 3 0.012
LYPD3 LY6/PLAUR domain containing 3 0.012
CABLES1 Cdk5 and Abl enzyme substrate 1 0.011
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.011
SKIL SKI-like oncogene 0.011
THBS1 thrombospondin 1 0.011
KRT14 keratin 14 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
Lamp2 lysosomal-associated membrane protein 2 0.248
Pebp1 phosphatidylethanolamine binding protein 1 0.145
Tmem205 transmembrane protein 205 0.144
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.132
Unc5b unc-5 homolog B (C. elegans) 0.112
Itpr3 inositol 1,4,5-triphosphate receptor, type 3 0.093
Ddt D-dopachrome tautomerase 0.086
Dchs1 dachsous 1 (Drosophila) 0.085
Ednra endothelin receptor type A 0.061
Atp5g2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) 0.060
Olr37 olfactory receptor 37 0.058
Smad7 SMAD family member 7 0.058
Gars glycyl-tRNA synthetase 0.057
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.056
Muc1 mucin 1, cell surface associated 0.055
Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.052
Dstn destrin 0.051
Sox2 SRY (sex determining region Y)-box 2 0.048
Tgfb2 transforming growth factor, beta 2 0.046
Cxcl2 chemokine (C-X-C motif) ligand 2 0.045
Tst thiosulfate sulfurtransferase 0.044
Fosl1 fos-like antigen 1 0.044
Slit3 slit homolog 3 (Drosophila) 0.043
Creb1 cAMP responsive element binding protein 1 0.042
Ppia peptidylprolyl isomerase A (cyclophilin A) 0.041
Ugt8 UDP glycosyltransferase 8 0.040
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.039
Tead2 TEA domain family member 2 0.037
Edn1 endothelin 1 0.036
Dnajb14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.036
Acy1 aminoacylase 1 0.035
Olr1398 olfactory receptor 1398 0.035
Kl Klotho 0.034
Olr837 olfactory receptor 837 0.033
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.033
Pcdhga11 protocadherin gamma subfamily A, 11 0.033
Ncam1 neural cell adhesion molecule 1 0.032
Nrarp Notch-regulated ankyrin repeat protein 0.032
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.032
Cdh4 cadherin 4 0.032
Prrx1 paired related homeobox 1 0.031
Mif macrophage migration inhibitory factor 0.031
Gja3 gap junction protein, alpha 3 0.030
Bmp3 bone morphogenetic protein 3 0.030
Iah1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) 0.030
Aldh9a1 aldehyde dehydrogenase 9 family, member A1 0.029
Hprt1 hypoxanthine phosphoribosyltransferase 1 0.029
Megf6 multiple EGF-like-domains 6 0.028
Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 0.028
Cbl Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.028
Nit2 nitrilase family, member 2 0.027
Add3 adducin 3 (gamma) 0.027
Plin perilipin 0.027
Tcf4 transcription factor 4 0.026
Nfya nuclear transcription factor-Y alpha 0.026
Akr7a2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.026
Tmem79 transmembrane protein 79 0.026
Arpc2 actin related protein 2/3 complex, subunit 2 0.025
Teddm1 transmembrane epididymal protein 1 0.025
Cdh16 cadherin 16 0.025
Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.025
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.025
Mars methionine-tRNA synthetase 0.024
RGD1310351 similar to RIKEN cDNA 4732418C07 0.023
Vcan versican 0.023
Slc27a3 solute carrier family 27 (fatty acid transporter), member 3 0.023
Col8a1 collagen, type VIII, alpha 1 0.023
Apba3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.022
Gja5 gap junction protein, alpha 5 0.022
Yars tyrosyl-tRNA synthetase 0.022
Socs3 suppressor of cytokine signaling 3 0.021
L3mbtl3 l(3)mbt-like 3 (Drosophila) 0.021
Tecr trans-2,3-enoyl-CoA reductase 0.021
Aif1l allograft inflammatory factor 1-like 0.021
LOC207127 similar to preprotein translocase 0.021
Erp44 endoplasmic reticulum protein 44 0.021
Cish cytokine inducible SH2-containing protein 0.021
Wnt5b wingless-type MMTV integration site family, member 5B 0.020
RT1-DOa RT1 class II, locus DOa 0.020
Gamt guanidinoacetate N-methyltransferase 0.020
LOC312273 Trypsin V-A 0.020
Met met proto-oncogene 0.020
Bsg basigin 0.020
Map2k2 mitogen activated protein kinase kinase 2 0.020
Msx2 msh homeobox 2 0.020
Plagl1 pleiomorphic adenoma gene-like 1 0.020
Dll3 delta-like 3 (Drosophila) 0.020
Chl1 cell adhesion molecule with homology to L1CAM 0.020
Eif3s6ip eukaryotic translation initiation factor 3, subunit 6 interacting protein 0.020
Stc1 stanniocalcin 1 0.019
Gstp1 glutathione S-transferase pi 1 0.019
Cldn3 claudin 3 0.019
Myo1a myosin IA 0.019
Cox8a cytochrome c oxidase subunit VIIIa 0.019
A4galt alpha 1,4-galactosyltransferase 0.019
RGD1565591 similar to Ski protein 0.019
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.019
Sstr1 somatostatin receptor 1 0.019
Jag2 jagged 2 0.019
Nono non-POU domain containing, octamer-binding 0.019
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism