The network for 'blood vessel endothelial cell migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

blood vessel endothelial cell migration

The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.

Mus musculus
Name Description Probability Func Analog Organism
Efnb2 ephrin B2 0.997
Notch1 Notch gene homolog 1 (Drosophila) 0.966
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.945
Nos3 nitric oxide synthase 3, endothelial cell 0.941
Jag1 jagged 1 0.918
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.916
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.903
Psen1 presenilin 1 0.896
Vegfa vascular endothelial growth factor A 0.830
Apoe apolipoprotein E 0.741
Kdr kinase insert domain protein receptor 0.738
Eng endoglin 0.732
Ephb2 Eph receptor B2 0.698
Cyr61 cysteine rich protein 61 0.679
Tgfb2 transforming growth factor, beta 2 0.640
Flt4 FMS-like tyrosine kinase 4 0.627
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.607
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.600
Gata4 GATA binding protein 4 0.580
Gli3 GLI-Kruppel family member GLI3 0.535
Fgfr1 fibroblast growth factor receptor 1 0.524
Epha4 Eph receptor A4 0.504
Flt1 FMS-like tyrosine kinase 1 0.495
Meox2 mesenchyme homeobox 2 0.459
Csf1 colony stimulating factor 1 (macrophage) 0.459
Notch2 Notch gene homolog 2 (Drosophila) 0.435
Ptk2 PTK2 protein tyrosine kinase 2 0.409
Ntf3 neurotrophin 3 0.407
Plxnd1 plexin D1 0.403
Rb1 retinoblastoma 1 0.374
Fgfr2 fibroblast growth factor receptor 2 0.373
Slit2 slit homolog 2 (Drosophila) 0.343
Efna1 ephrin A1 0.341
Dll1 delta-like 1 (Drosophila) 0.304
Smad3 MAD homolog 3 (Drosophila) 0.298
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.285
Slit3 slit homolog 3 (Drosophila) 0.283
Efnb1 ephrin B1 0.277
Pax1 paired box gene 1 0.260
Dock1 dedicator of cytokinesis 1 0.235
Tcte3 t-complex-associated testis expressed 3 0.231
Mef2d myocyte enhancer factor 2D 0.221
Itga5 integrin alpha 5 (fibronectin receptor alpha) 0.213
Hif1a hypoxia inducible factor 1, alpha subunit 0.209
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.194
Gata6 GATA binding protein 6 0.189
Gli2 GLI-Kruppel family member GLI2 0.184
Ephb3 Eph receptor B3 0.183
Sox7 SRY-box containing gene 7 0.169
Rag1 recombination activating gene 1 0.169
Itga3 integrin alpha 3 0.164
Cdh5 cadherin 5 0.152
Foxf2 forkhead box F2 0.148
Lrp1 low density lipoprotein receptor-related protein 1 0.146
Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 0.141
Foxg1 forkhead box G1 0.140
Lmna lamin A 0.139
Gdnf glial cell line derived neurotrophic factor 0.136
Nog noggin 0.128
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.128
Klf2 Kruppel-like factor 2 (lung) 0.127
Pax3 paired box gene 3 0.127
Vangl2 vang-like 2 (van gogh, Drosophila) 0.126
Actn1 actinin, alpha 1 0.121
Plcg1 phospholipase C, gamma 1 0.119
Itgb3 integrin beta 3 0.116
Col4a2 collagen, type IV, alpha 2 0.115
Bcl2 B-cell leukemia/lymphoma 2 0.115
Wwtr1 WW domain containing transcription regulator 1 0.114
Hlx H2.0-like homeobox 0.111
Egfr epidermal growth factor receptor 0.109
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.106
Prl7d1 prolactin family 7, subfamily d, member 1 0.104
Emp2 epithelial membrane protein 2 0.104
Tead1 TEA domain family member 1 0.103
Tgfb1 transforming growth factor, beta 1 0.100
Mmp15 matrix metallopeptidase 15 0.099
Ctnnb1 catenin (cadherin associated protein), beta 1 0.097
Ptk7 PTK7 protein tyrosine kinase 7 0.095
Dcx doublecortin 0.092
Prl8a6 prolactin family 8, subfamily a, member 6 0.092
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.092
Jup junction plakoglobin 0.091
Smad6 MAD homolog 6 (Drosophila) 0.090
Trp63 transformation related protein 63 0.090
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.089
Myo1c myosin IC 0.088
Emx1 empty spiracles homolog 1 (Drosophila) 0.087
Tgfb1i1 transforming growth factor beta 1 induced transcript 1 0.085
Cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.084
Snai1 snail homolog 1 (Drosophila) 0.083
Robo2 roundabout homolog 2 (Drosophila) 0.082
Nkx2-1 NK2 homeobox 1 0.082
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.082
Eya1 eyes absent 1 homolog (Drosophila) 0.079
Prl3d1 prolactin family 3, subfamily d, member 1 0.077
Chd7 chromodomain helicase DNA binding protein 7 0.074
F12 coagulation factor XII (Hageman factor) 0.073
Zfpm2 zinc finger protein, multitype 2 0.073
Notch3 Notch gene homolog 3 (Drosophila) 0.072
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
kdrl kinase insert domain receptor like 0.971
notch3 notch homolog 3 0.864
itgb1b.2 integrin, beta 1b.2 0.706
vegfc vascular endothelial growth factor c 0.676
dll4 delta-like 4 (Drosophila) 0.597
plcg1 phospholipase C, gamma 1 0.482
dlc deltaC 0.428
pak2a p21 (CDKN1A)-activated kinase 2a 0.419
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.406
tal1 T-cell acute lymphocytic leukemia 1 0.290
itgb1a integrin, beta 1a 0.249
efnb2a ephrin B2a 0.224
cdh5 cadherin 5 0.215
jag2 jagged 2 0.212
vegfaa vascular endothelial growth factor Aa 0.208
ntrk3b neurotrophic tyrosine kinase, receptor, type 3b 0.178
aox3 aldehyde oxidase 3 0.174
pax7b paired box gene 7b 0.172
cav1 caveolin 1 0.172
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.168
ptgs1 prostaglandin-endoperoxide synthase 1 0.157
cdh23 cadherin-like 23 0.157
lpar1 lysophosphatidic acid receptor 1 0.146
csf1ra colony stimulating factor 1 receptor, a 0.140
calcrla calcitonin receptor-like a 0.138
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.132
tbx2b T-box 2b 0.127
dld deltaD 0.126
epha4a eph receptor A4a 0.122
cxcr4b chemokine (C-X-C motif), receptor 4b 0.119
mmp2 matrix metalloproteinase 2 0.116
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.114
hsp47 heat shock protein 47 0.114
ptch2 patched 2 0.112
nrp2a neuropilin 2a 0.109
itgb1b integrin, beta 1b 0.109
smad9 MAD homolog 9 (Drosophila) 0.106
dlb deltaB 0.100
ntn4 netrin 4 0.096
myod1 myogenic differentiation 1 0.093
mitfa microphthalmia-associated transcription factor a 0.092
plxnd1 plexin D1 0.091
acta2 actin, alpha 2, smooth muscle, aorta 0.089
hdac4 histone deacetylase 4 0.088
LOC100003514 protein kinase C alpha type-like 0.085
lef1 lymphocyte enhancer binding factor 1 0.083
cxcr4a chemokine (C-X-C motif) receptor 4a 0.083
ptprf protein tyrosine phosphatase, receptor type, F 0.082
sdc2 syndecan 2 0.079
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.076
nrp1a neuropilin 1a 0.074
myh11a myosin, heavy polypeptide 11, smooth muscle a 0.073
ikzf5 IKAROS family zinc finger 5 0.073
ptprk protein tyrosine phosphatase, receptor type, K 0.072
spry4 sprouty (Drosophila) homolog 4 0.068
dsc2l desmocollin 2 like 0.068
slc16a3 solute carrier family 16 (monocarboxylic acid transporters), member 3 0.066
pparg peroxisome proliferator activated receptor gamma 0.066
itgb3b integrin beta 3b 0.066
dusp5 dual specificity phosphatase 5 0.065
lpp LIM domain containing preferred translocation partner in lipoma 0.064
fstl1b follistatin-like 1b 0.063
csrp1a cysteine and glycine-rich protein 1a 0.063
ntn1a netrin 1a 0.059
pcsk5a proprotein convertase subtilisin/kexin type 5a 0.059
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.058
sardh sarcosine dehydrogenase 0.057
etv2 ets variant gene 2 0.056
pdgfrb2 platelet derived growth factor receptor beta 2 0.056
pax8 paired box gene 8 0.055
emx3 empty spiracles homeobox 3 0.055
antxr1 anthrax toxin receptor 1 0.054
ptprc protein tyrosine phosphatase, receptor type, C 0.054
ascl1a achaete-scute complex-like 1a (Drosophila) 0.052
ccm2 cerebral cavernous malformation 2 0.052
mcamb melanoma cell adhesion molecule b 0.051
alcamb activated leukocyte cell adhesion molecule b 0.050
sgk1 serum/glucocorticoid regulated kinase 1 0.049
si:ch211-212m21.5 si:ch211-212m21.5 0.048
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.048
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.047
twist1a twist1a 0.046
pcsk5b proprotein convertase subtilisin/kexin type 5b 0.045
itgav integrin, alpha V 0.045
crb2a crumbs homolog 2a 0.044
smad1 MAD homolog 1 (Drosophila) 0.044
si:ch73-60e21.1 si:ch73-60e21.1 0.043
mpll myeloproliferative leukemia virus oncogene, like 0.043
ptrfb polymerase I and transcript release factor b 0.042
unc5b unc-5 homolog B (C. elegans) 0.042
kitlga kit ligand a 0.042
guca1c guanylate cyclase activator 1C 0.041
fabp11a fatty acid binding protein 11a 0.041
furinb furin (paired basic amino acid cleaving enzyme) b 0.041
ren renin 0.040
pax7a paired box gene 7a 0.040
tll1 tolloid-like 1 0.039
ryr3 ryanodine receptor 3 0.039
wt1b wilms tumor 1b 0.039
gli2b GLI-Kruppel family member GLI2b 0.038
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FN1 fibronectin 1 1.000
JAG1 jagged 1 0.994
FGFR2 fibroblast growth factor receptor 2 0.992
FLNA filamin A, alpha 0.990
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.985
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.980
ENG endoglin 0.979
YAP1 Yes-associated protein 1 0.978
TEK TEK tyrosine kinase, endothelial 0.972
VEGFA vascular endothelial growth factor A 0.945
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.941
TGFB1 transforming growth factor, beta 1 0.936
BMP2 bone morphogenetic protein 2 0.924
NCF1 neutrophil cytosolic factor 1 0.922
NOTCH1 notch 1 0.915
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.878
FKBP1A FK506 binding protein 1A, 12kDa 0.876
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.874
ZYX zyxin 0.870
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.868
JUN jun proto-oncogene 0.863
NRP1 neuropilin 1 0.841
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.837
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.834
NOTCH3 notch 3 0.818
KLF4 Kruppel-like factor 4 (gut) 0.809
BAG3 BCL2-associated athanogene 3 0.799
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.794
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.724
FGF1 fibroblast growth factor 1 (acidic) 0.672
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.660
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.651
FOS FBJ murine osteosarcoma viral oncogene homolog 0.642
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.640
EGR1 early growth response 1 0.636
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.628
ACTB actin, beta 0.620
SMAD7 SMAD family member 7 0.618
PDLIM7 PDZ and LIM domain 7 (enigma) 0.611
EGR3 early growth response 3 0.582
MEF2C myocyte enhancer factor 2C 0.573
CYR61 cysteine-rich, angiogenic inducer, 61 0.554
FGFR1 fibroblast growth factor receptor 1 0.528
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.505
AMOTL1 angiomotin like 1 0.484
LCK lymphocyte-specific protein tyrosine kinase 0.457
NOXA1 NADPH oxidase activator 1 0.414
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.413
MYH9 myosin, heavy chain 9, non-muscle 0.413
CRYAB crystallin, alpha B 0.393
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.374
HDAC7 histone deacetylase 7 0.349
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.342
EPHA7 EPH receptor A7 0.337
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.316
THBS1 thrombospondin 1 0.307
ACTN4 actinin, alpha 4 0.300
ILK integrin-linked kinase 0.300
GRB7 growth factor receptor-bound protein 7 0.295
FYN FYN oncogene related to SRC, FGR, YES 0.291
PRKCA protein kinase C, alpha 0.288
FBLN1 fibulin 1 0.281
HP haptoglobin 0.270
A2M alpha-2-macroglobulin 0.269
PSEN2 presenilin 2 (Alzheimer disease 4) 0.262
SKIL SKI-like oncogene 0.261
POU3F2 POU class 3 homeobox 2 0.235
AMOT angiomotin 0.233
TGFBR1 transforming growth factor, beta receptor 1 0.230
HSPG2 heparan sulfate proteoglycan 2 0.213
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.212
PXN paxillin 0.208
ACTN1 actinin, alpha 1 0.198
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.193
PRKCD protein kinase C, delta 0.190
MSN moesin 0.189
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.189
PTPRB protein tyrosine phosphatase, receptor type, B 0.188
LAT linker for activation of T cells 0.188
EGR2 early growth response 2 0.182
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.180
FGA fibrinogen alpha chain 0.179
TLN1 talin 1 0.175
IER2 immediate early response 2 0.174
PAX3 paired box 3 0.171
LMNA lamin A/C 0.169
POU5F1 POU class 5 homeobox 1 0.168
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.163
TPM4 tropomyosin 4 0.161
EFNA1 ephrin-A1 0.156
PLCG1 phospholipase C, gamma 1 0.155
ANXA1 annexin A1 0.149
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.148
JAG2 jagged 2 0.147
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.147
JUNB jun B proto-oncogene 0.146
DUSP1 dual specificity phosphatase 1 0.146
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.145
EFNA5 ephrin-A5 0.145
FHL2 four and a half LIM domains 2 0.145
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism