The network for 'negative regulation of growth of symbiont involved in interaction with host' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of growth of symbiont involved in interaction with host

Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.

Mus musculus
Name Description Probability Func Analog Organism
Tnf tumor necrosis factor 0.984
Fasl Fas ligand (TNF superfamily, member 6) 0.977
Tlr4 toll-like receptor 4 0.918
Lta lymphotoxin A 0.839
Il10 interleukin 10 0.815
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.707
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.689
Cd44 CD44 antigen 0.658
Apoe apolipoprotein E 0.656
Cd40 CD40 antigen 0.547
Ldlr low density lipoprotein receptor 0.474
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.409
Ccl4 chemokine (C-C motif) ligand 4 0.376
Mpo myeloperoxidase 0.371
Nos2 nitric oxide synthase 2, inducible 0.369
Elane elastase, neutrophil expressed 0.312
Myd88 myeloid differentiation primary response gene 88 0.297
Ctsg cathepsin G 0.295
Cma1 chymase 1, mast cell 0.292
Ticam1 toll-like receptor adaptor molecule 1 0.271
Cxcr5 chemokine (C-X-C motif) receptor 5 0.260
Unc93b1 unc-93 homolog B1 (C. elegans) 0.244
Pdcd1 programmed cell death 1 0.233
Ngp neutrophilic granule protein 0.230
Camp cathelicidin antimicrobial peptide 0.226
Ltf lactotransferrin 0.210
Klra9 killer cell lectin-like receptor subfamily A, member 9 0.204
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.166
Ms4a3 membrane-spanning 4-domains, subfamily A, member 3 0.163
Ifnar2 interferon (alpha and beta) receptor 2 0.151
Ccr2 chemokine (C-C motif) receptor 2 0.150
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.148
Mmp9 matrix metallopeptidase 9 0.146
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.145
Pou2af1 POU domain, class 2, associating factor 1 0.142
Mcpt8 mast cell protease 8 0.134
Ccl2 chemokine (C-C motif) ligand 2 0.129
Mmp8 matrix metallopeptidase 8 0.128
Cxcl13 chemokine (C-X-C motif) ligand 13 0.127
Il4 interleukin 4 0.121
Xcl1 chemokine (C motif) ligand 1 0.120
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.113
Il1r1 interleukin 1 receptor, type I 0.101
Ncr1 natural cytotoxicity triggering receptor 1 0.098
Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) 0.096
Il12rb1 interleukin 12 receptor, beta 1 0.095
Lyz2 lysozyme 2 0.094
Oas3 2'-5' oligoadenylate synthetase 3 0.093
Gbp1 guanylate binding protein 1 0.083
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.082
Il7 interleukin 7 0.081
Prg2 proteoglycan 2, bone marrow 0.081
Irg1 immunoresponsive gene 1 0.079
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.079
Cd19 CD19 antigen 0.078
Cd7 CD7 antigen 0.077
Stat2 signal transducer and activator of transcription 2 0.077
Rhd Rh blood group, D antigen 0.075
Il2rb interleukin 2 receptor, beta chain 0.074
Cpa3 carboxypeptidase A3, mast cell 0.074
Cst7 cystatin F (leukocystatin) 0.072
Duox2 dual oxidase 2 0.072
Ltb lymphotoxin B 0.068
Jak3 Janus kinase 3 0.065
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.064
Itgal integrin alpha L 0.064
Gp1ba glycoprotein 1b, alpha polypeptide 0.064
Vdr vitamin D receptor 0.063
Ifng interferon gamma 0.062
Il22 interleukin 22 0.060
Batf basic leucine zipper transcription factor, ATF-like 0.057
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.055
Il1b interleukin 1 beta 0.055
Slpi secretory leukocyte peptidase inhibitor 0.054
Gfi1b growth factor independent 1B 0.053
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.052
Tbx21 T-box 21 0.050
Nlrp3 NLR family, pyrin domain containing 3 0.050
Ooep oocyte expressed protein homolog (dog) 0.049
Gzmb granzyme B 0.047
Casp1 caspase 1 0.047
Dsg4 desmoglein 4 0.047
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.046
Ubd ubiquitin D 0.045
Klf1 Kruppel-like factor 1 (erythroid) 0.045
Esr1 estrogen receptor 1 (alpha) 0.044
Cxcl10 chemokine (C-X-C motif) ligand 10 0.042
Irak1 interleukin-1 receptor-associated kinase 1 0.042
F2rl2 coagulation factor II (thrombin) receptor-like 2 0.041
Tnfrsf13b tumor necrosis factor receptor superfamily, member 13b 0.041
Trem3 triggering receptor expressed on myeloid cells 3 0.040
Tlr2 toll-like receptor 2 0.040
Sfrp4 secreted frizzled-related protein 4 0.039
Lyl1 lymphoblastomic leukemia 1 0.038
Nkg7 natural killer cell group 7 sequence 0.038
1810019J16Rik RIKEN cDNA 1810019J16 gene 0.038
Aoah acyloxyacyl hydrolase 0.037
Prf1 perforin 1 (pore forming protein) 0.037
Lipc lipase, hepatic 0.036
Gzmd granzyme D 0.036
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rel Relish 0.185
Rab7 Rab-protein 7 0.133
ird1 immune response deficient 1 0.126
Rheb CG1081 gene product from transcript CG1081-RA 0.123
vps2 CG14542 gene product from transcript CG14542-RA 0.095
shrb shrub 0.080
drpr draper 0.069
SNF1A SNF1A/AMP-activated protein kinase 0.053
Crag Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein 0.050
Mgat1 UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I 0.048
CG1347 CG1347 gene product from transcript CG1347-RB 0.046
mys myospheroid 0.042
mop myopic 0.039
HLH106 Helix loop helix protein 106 0.035
Atg7 Autophagy-specific gene 7 0.031
snama something that sticks like glue 0.026
Xbp1 X box binding protein-1 0.025
Atg8a Autophagy-specific gene 8a 0.021
Fatp Fatty acid (long chain) transport protein 0.020
eIF-1A Eukaryotic initiation factor 1A 0.020
TSG101 tumor suppressor protein 101 0.020
Thor CG8846 gene product from transcript CG8846-RA 0.019
Mmp1 Matrix metalloproteinase 1 0.019
lqf liquid facets 0.018
CG11791 CG11791 gene product from transcript CG11791-RB 0.018
Rfabg Retinoid- and fatty acid-binding glycoprotein 0.017
vps24 Charged multivesicular body protein 3 0.017
imd immune deficiency 0.016
CG10103 CG10103 gene product from transcript CG10103-RA 0.016
Chc Clathrin heavy chain 0.015
bun bunched 0.015
Marf Mitochondrial assembly regulatory factor 0.014
Rab2 Rab-protein 2 0.014
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.012
A3-3 CG11405 gene product from transcript CG11405-RA 0.012
BG4 CG12297 gene product from transcript CG12297-RA 0.012
rhea CG6831 gene product from transcript CG6831-RA 0.011
CdsA CDP diglyceride synthetase 0.011
Dlic Dynein light intermediate chain 0.011
Sc2 CG10849 gene product from transcript CG10849-RA 0.011
sw short wing 0.011
Dredd Death related ced-3/Nedd2-like protein 0.011
Lk6 CG17342 gene product from transcript CG17342-RA 0.010
Pi3K68D Phosphotidylinositol 3 kinase 68D 0.010
AGO2 Argonaute 2 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.972
TLR4 toll-like receptor 4 0.562
IRAK1 interleukin-1 receptor-associated kinase 1 0.482
IRAK3 interleukin-1 receptor-associated kinase 3 0.477
PDCD6IP programmed cell death 6 interacting protein 0.475
IRAK2 interleukin-1 receptor-associated kinase 2 0.440
MYD88 myeloid differentiation primary response gene (88) 0.264
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.227
IRAK4 interleukin-1 receptor-associated kinase 4 0.197
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.165
CHMP1A chromatin modifying protein 1A 0.148
DHCR7 7-dehydrocholesterol reductase 0.133
SH3KBP1 SH3-domain kinase binding protein 1 0.114
FDPS farnesyl diphosphate synthase 0.099
TLR2 toll-like receptor 2 0.092
SAMHD1 SAM domain and HD domain 1 0.071
TICAM2 toll-like receptor adaptor molecule 2 0.042
DHCR24 24-dehydrocholesterol reductase 0.036
EIF1B eukaryotic translation initiation factor 1B 0.034
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.034
SH3GL2 SH3-domain GRB2-like 2 0.033
IQGAP1 IQ motif containing GTPase activating protein 1 0.033
CHMP4B chromatin modifying protein 4B 0.033
FADS2 fatty acid desaturase 2 0.032
DMBT1 deleted in malignant brain tumors 1 0.031
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.031
PELI3 pellino homolog 3 (Drosophila) 0.031
FADS1 fatty acid desaturase 1 0.030
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.029
PRTN3 proteinase 3 0.028
CHMP5 chromatin modifying protein 5 0.027
SPOP speckle-type POZ protein 0.023
TLR7 toll-like receptor 7 0.023
SC4MOL sterol-C4-methyl oxidase-like 0.022
PDCD6 programmed cell death 6 0.022
SFTPD surfactant protein D 0.022
INSIG1 insulin induced gene 1 0.021
RNF41 ring finger protein 41 0.020
STARD4 StAR-related lipid transfer (START) domain containing 4 0.020
DPT dermatopontin 0.018
ELANE elastase, neutrophil expressed 0.018
CMA1 chymase 1, mast cell 0.018
SQLE squalene epoxidase 0.018
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.017
STAP2 signal transducing adaptor family member 2 0.017
OCRL oculocerebrorenal syndrome of Lowe 0.015
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.015
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.015
SFTPB surfactant protein B 0.015
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.015
MPO myeloperoxidase 0.014
BPI bactericidal/permeability-increasing protein 0.014
LRP1 low density lipoprotein receptor-related protein 1 0.014
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) 0.014
CFD complement factor D (adipsin) 0.013
PLIN1 perilipin 1 0.013
CD2AP CD2-associated protein 0.013
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.013
RAB6A RAB6A, member RAS oncogene family 0.013
ATG9A ATG9 autophagy related 9 homolog A (S. cerevisiae) 0.012
DOCK8 dedicator of cytokinesis 8 0.012
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.012
BABAM1 BRISC and BRCA1 A complex member 1 0.012
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 0.011
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.011
CTSG cathepsin G 0.011
DYNLT1 dynein, light chain, Tctex-type 1 0.011
EXOC8 exocyst complex component 8 0.011
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.011
HBD hemoglobin, delta 0.010
SREBF1 sterol regulatory element binding transcription factor 1 0.010
LTF lactotransferrin 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism