Process View
The network for 'negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Chrd | chordin | 0.978 | |
Nodal | nodal | 0.968 | |
Fgf10 | fibroblast growth factor 10 | 0.936 | |
Notch1 | Notch gene homolog 1 (Drosophila) | 0.935 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.909 | |
Pten | phosphatase and tensin homolog | 0.898 | |
Smad6 | MAD homolog 6 (Drosophila) | 0.871 | |
Wnt5a | wingless-related MMTV integration site 5A | 0.836 | |
Bcl2 | B-cell leukemia/lymphoma 2 | 0.832 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.800 | |
Bgn | biglycan | 0.779 | |
Tbx3 | T-box 3 | 0.779 | |
Wnt3a | wingless-related MMTV integration site 3A | 0.778 | |
Fgfr1 | fibroblast growth factor receptor 1 | 0.670 | |
Bmp4 | bone morphogenetic protein 4 | 0.666 | |
Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.637 | |
Smad7 | MAD homolog 7 (Drosophila) | 0.621 | |
Sfrp2 | secreted frizzled-related protein 2 | 0.552 | |
Smad3 | MAD homolog 3 (Drosophila) | 0.544 | |
Hif1a | hypoxia inducible factor 1, alpha subunit | 0.534 | |
Pitx2 | paired-like homeodomain transcription factor 2 | 0.489 | |
Nog | noggin | 0.478 | |
Gli3 | GLI-Kruppel family member GLI3 | 0.457 | |
Rarb | retinoic acid receptor, beta | 0.450 | |
Acvr1 | activin A receptor, type 1 | 0.448 | |
Psen1 | presenilin 1 | 0.439 | |
T | brachyury | 0.438 | |
Gli2 | GLI-Kruppel family member GLI2 | 0.425 | |
Dll4 | delta-like 4 (Drosophila) | 0.416 | |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.402 | |
Axin1 | axin 1 | 0.399 | |
Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.385 | |
Axin2 | axin2 | 0.383 | |
Lhx1 | LIM homeobox protein 1 | 0.362 | |
Emx1 | empty spiracles homolog 1 (Drosophila) | 0.359 | |
Zic3 | zinc finger protein of the cerebellum 3 | 0.358 | |
Smad4 | MAD homolog 4 (Drosophila) | 0.352 | |
Inhba | inhibin beta-A | 0.349 | |
Amhr2 | anti-Mullerian hormone type 2 receptor | 0.341 | |
Efnb2 | ephrin B2 | 0.337 | |
Fzd1 | frizzled homolog 1 (Drosophila) | 0.324 | |
Tbx2 | T-box 2 | 0.302 | |
Gas1 | growth arrest specific 1 | 0.290 | |
Ptk2 | PTK2 protein tyrosine kinase 2 | 0.287 | |
Wnt3 | wingless-related MMTV integration site 3 | 0.285 | |
Ror1 | receptor tyrosine kinase-like orphan receptor 1 | 0.281 | |
Pax8 | paired box gene 8 | 0.280 | |
Gdf1 | growth differentiation factor 1 | 0.280 | |
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.274 | |
Tgfbr1 | transforming growth factor, beta receptor I | 0.271 | |
Fzd8 | frizzled homolog 8 (Drosophila) | 0.271 | |
Otx2 | orthodenticle homolog 2 (Drosophila) | 0.269 | |
Wnt4 | wingless-related MMTV integration site 4 | 0.266 | |
Lrp5 | low density lipoprotein receptor-related protein 5 | 0.263 | |
Lum | lumican | 0.261 | |
Gopc | golgi associated PDZ and coiled-coil motif containing | 0.258 | |
Dll1 | delta-like 1 (Drosophila) | 0.252 | |
Apc | adenomatosis polyposis coli | 0.249 | |
Hic1 | hypermethylated in cancer 1 | 0.240 | |
Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.239 | |
Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.229 | |
Timp2 | tissue inhibitor of metalloproteinase 2 | 0.227 | |
Ptgfr | prostaglandin F receptor | 0.224 | |
Gpc3 | glypican 3 | 0.224 | |
Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.222 | |
Cdx2 | caudal type homeobox 2 | 0.222 | |
Fmod | fibromodulin | 0.218 | |
Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.216 | |
Sox9 | SRY-box containing gene 9 | 0.210 | |
Foxh1 | forkhead box H1 | 0.208 | |
Gdnf | glial cell line derived neurotrophic factor | 0.208 | |
Smo | smoothened homolog (Drosophila) | 0.207 | |
Sox2 | SRY-box containing gene 2 | 0.202 | |
Sfrp1 | secreted frizzled-related protein 1 | 0.202 | |
Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.201 | |
Eng | endoglin | 0.196 | |
Pitx1 | paired-like homeodomain transcription factor 1 | 0.194 | |
Foxa2 | forkhead box A2 | 0.193 | |
Pou3f3 | POU domain, class 3, transcription factor 3 | 0.193 | |
Scn5a | sodium channel, voltage-gated, type V, alpha | 0.191 | |
Sall1 | sal-like 1 (Drosophila) | 0.191 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.187 | |
Gsk3b | glycogen synthase kinase 3 beta | 0.182 | |
Tgfa | transforming growth factor alpha | 0.179 | |
Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.176 | |
Dvl1 | dishevelled, dsh homolog 1 (Drosophila) | 0.175 | |
Hbb-b1 | hemoglobin, beta adult major chain | 0.172 | |
Rarg | retinoic acid receptor, gamma | 0.172 | |
Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.171 | |
Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.168 | |
Dlg1 | discs, large homolog 1 (Drosophila) | 0.168 | |
Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.167 | |
Acvrl1 | activin A receptor, type II-like 1 | 0.166 | |
Pdgfa | platelet derived growth factor, alpha | 0.165 | |
Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.162 | |
Notch3 | Notch gene homolog 3 (Drosophila) | 0.157 | |
Lef1 | lymphoid enhancer binding factor 1 | 0.156 | |
Dkk3 | dickkopf homolog 3 (Xenopus laevis) | 0.155 | |
Bptf | bromodomain PHD finger transcription factor | 0.154 | |
Notch2 | Notch gene homolog 2 (Drosophila) | 0.154 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
vab-3 | Protein VAB-3 | 0.321 | |
unc-7 | Protein UNC-7 | 0.258 | |
tag-320 | Protein TAG-320 | 0.155 | |
che-3 | Protein CHE-3 | 0.118 | |
ncam-1 | Protein NCAM-1 | 0.113 | |
daf-1 | Protein DAF-1 | 0.107 | |
daf-3 | Protein DAF-3 | 0.106 | |
inx-4 | Protein INX-4 | 0.097 | |
egl-8 | Protein EGL-8 | 0.082 | |
mec-2 | Protein MEC-2 | 0.081 | |
unc-36 | Protein UNC-36 | 0.079 | |
eat-4 | Protein EAT-4 | 0.059 | |
daf-10 | Protein DAF-10 | 0.054 | |
che-13 | Protein CHE-13 | 0.052 | |
osm-6 | Protein OSM-6 | 0.043 | |
scrm-1 | Protein SCRM-1 | 0.040 | |
daf-11 | Protein DAF-11 | 0.037 | |
daf-19 | Protein DAF-19 | 0.035 | |
ZC506.1 | Protein ZC506.1 | 0.034 | |
hsp-1 | Protein HSP-1 | 0.030 | |
imp-2 | Protein IMP-2 | 0.029 | |
daf-4 | Protein DAF-4 | 0.029 | |
C06G1.5 | Protein C06G1.5 | 0.027 | |
B0035.6 | Protein B0035.6 | 0.025 | |
pqn-62 | Protein PQN-62 | 0.023 | |
chd-7 | Protein CHD-7 | 0.023 | |
lin-25 | Protein LIN-25 | 0.023 | |
unc-9 | Protein UNC-9 | 0.022 | |
sma-9 | Protein SMA-9 | 0.020 | |
R05G6.10 | Protein R05G6.10 | 0.020 | |
che-2 | Protein CHE-2 | 0.019 | |
che-1 | Protein CHE-1 | 0.019 | |
vab-8 | Protein VAB-8 | 0.019 | |
elt-6 | Protein ELT-6 | 0.018 | |
mec-1 | Protein MEC-1 | 0.017 | |
CELE_F25E5.1 | Protein F25E5.1 | 0.017 | |
nhr-10 | Protein NHR-10 | 0.017 | |
T14G8.3 | Protein T14G8.3 | 0.017 | |
osm-3 | Protein OSM-3 | 0.016 | |
che-11 | Protein CHE-11 | 0.016 | |
tag-241 | Protein TAG-241 | 0.015 | |
abl-1 | Protein ABL-1 | 0.015 | |
eat-6 | Protein EAT-6 | 0.015 | |
E01B7.1 | Protein E01B7.1 | 0.014 | |
R10E4.1 | Protein R10E4.1 | 0.014 | |
nhr-67 | Protein NHR-67 | 0.013 | |
Y40C5A.1 | Protein Y40C5A.1 | 0.011 | |
F13H10.4 | Protein F13H10.4 | 0.010 | |
osm-5 | Protein OSM-5 | 0.010 | |
sdc-2 | Protein SDC-2 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
bmp2b | bone morphogenetic protein 2b | 0.948 | |
hdac4 | histone deacetylase 4 | 0.445 | |
flh | floating head | 0.262 | |
raraa | retinoic acid receptor, alpha a | 0.254 | |
rasl11b | RAS-like, family 11, member B | 0.253 | |
nanos3 | nanos homolog 3 | 0.229 | |
tbx1 | T-box 1 | 0.215 | |
si:ch211-173o4.2 | si:ch211-173o4.2 | 0.182 | |
nkx2.5 | NK2 transcription factor related 5 | 0.181 | |
nr3c1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.170 | |
kif5bb | kinesin family member 5B, b | 0.162 | |
brd2b | bromodomain containing 2b | 0.150 | |
bmp4 | bone morphogenetic protein 4 | 0.147 | |
rarga | retinoic acid receptor gamma a | 0.141 | |
LOC100000687 | signal peptide, CUB and EGF-like domain-containing protein 3-like | 0.114 | |
mib | mind bomb | 0.111 | |
hspb7 | heat shock protein family, alpha-crystallin-related, b7 | 0.108 | |
col11a1a | collagen, type XI, alpha 1a | 0.094 | |
ctsl1b | cathepsin L, 1 b | 0.087 | |
ippk | inositol 1,3,4,5,6-pentakisphosphate 2-kinase | 0.086 | |
gpia | glucose phosphate isomerase a | 0.085 | |
wnt9a | wingless-type MMTV integration site family, member 9A | 0.084 | |
efnb2a | ephrin B2a | 0.084 | |
rxrga | retinoid x receptor, gamma a | 0.083 | |
gng2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.081 | |
pcdh18b | protocadherin 18b | 0.081 | |
cacnb4b | calcium channel, voltage-dependent, beta 4b subunit | 0.076 | |
rxraa | retinoid X receptor, alpha a | 0.073 | |
smad1 | MAD homolog 1 (Drosophila) | 0.070 | |
tcf7 | transcription factor 7 (T-cell specific, HMG-box) | 0.069 | |
gbx2 | gastrulation brain homeo box 2 | 0.069 | |
dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.067 | |
lft1 | lefty1 | 0.064 | |
elavl2 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) | 0.063 | |
grnb | granulin b | 0.062 | |
nog1 | noggin 1 | 0.060 | |
twist3 | twist3 | 0.060 | |
cdx1b | caudal type homeobox 1 b | 0.060 | |
dact2 | dapper homolog 2, antagonist of beta-catenin (xenopus) | 0.059 | |
foxo3b | forkhead box O3b | 0.059 | |
frzb | frizzled-related protein | 0.056 | |
tp53bp2 | tumor protein p53 binding protein, 2 | 0.055 | |
vasa | vasa homolog | 0.055 | |
nog2 | noggin 2 | 0.053 | |
col7a1l | collagen type VII alpha 1-like | 0.052 | |
wnt5b | wingless-type MMTV integration site family, member 5b | 0.051 | |
gng7 | guanine nucleotide binding protein (G protein), gamma 7 | 0.050 | |
foxa3 | forkhead box A3 | 0.049 | |
gng12a | guanine nucleotide binding protein (G protein), gamma 12a | 0.049 | |
cdon | cell adhesion molecule-related/down-regulated by oncogenes | 0.048 | |
mbnl2 | muscleblind-like 2 (Drosophila) | 0.048 | |
e2f5 | E2F transcription factor 5 | 0.048 | |
LOC568379 | von Willebrand factor A domain-containing protein 1-like | 0.045 | |
spon2b | spondin 2b, extracellular matrix protein | 0.045 | |
btg1 | B-cell translocation gene 1 | 0.045 | |
tbx2b | T-box 2b | 0.044 | |
has2 | hyaluronan synthase 2 | 0.044 | |
smoc1 | SPARC related modular calcium binding 1 | 0.044 | |
bmp7b | bone morphogenetic protein 7b | 0.044 | |
satb2 | SATB homeobox 2 | 0.044 | |
cdx4 | caudal type homeo box transcription factor 4 | 0.043 | |
thbs1 | thrombospondin 1 | 0.043 | |
smad7 | MAD, mothers against decapentaplegic homolog 7 (Drosophila) | 0.043 | |
camk2n2 | calcium/calmodulin-dependent protein kinase II inhibitor 2 | 0.042 | |
rarab | retinoic acid receptor, alpha b | 0.042 | |
wnt11 | wingless-type MMTV integration site family, member 11 | 0.041 | |
cxcl12b | chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) | 0.041 | |
ncl1 | nicalin | 0.041 | |
si:ch211-173b8.2 | si:ch211-173b8.2 | 0.040 | |
matn4 | matrilin 4 | 0.040 | |
col5a2l | collagen, type V, alpha 2-like | 0.039 | |
plod3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 0.039 | |
col2a1a | collagen type II, alpha-1a | 0.039 | |
bmp2a | bone morphogenetic protein 2a | 0.038 | |
zbtb4 | zinc finger and BTB domain containing 4 | 0.038 | |
igfbp1a | insulin-like growth factor binding protein 1a | 0.038 | |
gng8 | guanine nucleotide binding protein (G protein), gamma 8 | 0.037 | |
sox17 | SRY-box containing gene 17 | 0.037 | |
bhlhe41 | basic helix-loop-helix family, member e41 | 0.037 | |
fgfr3 | fibroblast growth factor receptor 3 | 0.037 | |
zgc:136773 | zgc:136773 | 0.037 | |
nav3 | neuron navigator 3 | 0.036 | |
igfbp6b | insulin-like growth factor binding protein 6b | 0.036 | |
gadd45ba | growth arrest and DNA-damage-inducible, beta a | 0.036 | |
loxl2b | lysyl oxidase-like 2b | 0.036 | |
wnt8a | wingless-type MMTV integration site family, member 8a | 0.036 | |
ets1a | v-ets erythroblastosis virus E26 oncogene homolog 1a | 0.035 | |
cftr | cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) | 0.035 | |
LOC100000500 | sclerostin-like | 0.035 | |
fgf17 | fibroblast growth factor 17 | 0.035 | |
oep | one-eyed pinhead | 0.035 | |
arg2 | arginase, type II | 0.035 | |
si:dkeyp-34c12.2 | si:dkeyp-34c12.2 | 0.035 | |
mef2a | myocyte enhancer factor 2a | 0.034 | |
gli2a | GLI-Kruppel family member GLI2a | 0.034 | |
dusp6 | dual specificity phosphatase 6 | 0.033 | |
gata4 | GATA-binding protein 4 | 0.033 | |
epb4.1l4 | erythrocyte protein band 4.1-like 4 | 0.033 | |
szl | sizzled | 0.033 | |
bmpr1aa | bone morphogenetic protein receptor, type 1aa | 0.032 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Mad | Mothers against dpp | 0.954 | |
tkv | thickveins | 0.825 | |
Ras85D | Ras oncogene at 85D | 0.786 | |
hh | hedgehog | 0.538 | |
Egfr | Epidermal growth factor receptor | 0.385 | |
wit | wishful thinking | 0.354 | |
babo | baboon | 0.250 | |
sbb | scribbler | 0.161 | |
kay | kayak | 0.160 | |
put | punt | 0.137 | |
daw | dawdle | 0.134 | |
ash1 | absent, small, or homeotic discs 1 | 0.127 | |
gbb | glass bottom boat | 0.116 | |
Sulf1 | Sulfated | 0.111 | |
cwo | clockwork orange | 0.111 | |
cv-2 | crossveinless 2 | 0.109 | |
ci | cubitus interruptus | 0.105 | |
pho | pleiohomeotic | 0.102 | |
fu | fused | 0.095 | |
Dad | Daughters against dpp | 0.095 | |
CG14614 | CG14614 gene product from transcript CG14614-RA | 0.089 | |
Lasp | CG3849 gene product from transcript CG3849-RB | 0.087 | |
Ubqn | Ubiquilin | 0.087 | |
wun | wunen | 0.084 | |
mof | males absent on the first | 0.079 | |
JIL-1 | CG6297 gene product from transcript CG6297-RA | 0.078 | |
mxc | multi sex combs | 0.073 | |
NFAT | NFAT homolog | 0.071 | |
Pi3K92E | CG4141 gene product from transcript CG4141-RB | 0.064 | |
calypso | CG8445 gene product from transcript CG8445-RB | 0.063 | |
kis | kismet | 0.059 | |
kek5 | kekkon5 | 0.057 | |
endoA | endophilin A | 0.055 | |
CG9139 | CG9139 gene product from transcript CG9139-RA | 0.053 | |
Hcf | Host cell factor | 0.053 | |
Suv4-20 | CG13363 gene product from transcript CG13363-RA | 0.053 | |
neuroligin | CG13772 gene product from transcript CG13772-RA | 0.052 | |
mael | maelstrom | 0.046 | |
CG31122 | CG31122 gene product from transcript CG31122-RA | 0.045 | |
ast | asteroid | 0.043 | |
argos | CG4531 gene product from transcript CG4531-RA | 0.043 | |
msl-2 | male-specific lethal 2 | 0.043 | |
park | parkin | 0.042 | |
sqz | squeeze | 0.042 | |
mei-41 | meiotic 41 | 0.041 | |
rl | rolled | 0.040 | |
dpn | deadpan | 0.038 | |
ey | eyeless | 0.037 | |
dpp | decapentaplegic | 0.036 | |
l(2)gl | lethal (2) giant larvae | 0.036 | |
Eip93F | CG18389 gene product from transcript CG18389-RB | 0.035 | |
stj | straightjacket | 0.035 | |
chrw | chrowded | 0.034 | |
Eip63E | Ecdysone-induced protein 63E | 0.034 | |
tok | tolkin | 0.034 | |
piwi | CG6122 gene product from transcript CG6122-RA | 0.033 | |
GluRIIA | Glutamate receptor IIA | 0.033 | |
CG10200 | CG10200 gene product from transcript CG10200-RB | 0.032 | |
Sara | Smad anchor for receptor activation | 0.032 | |
Med | Medea | 0.032 | |
wnd | wallenda | 0.030 | |
mys | myospheroid | 0.030 | |
CG11347 | CG11347 gene product from transcript CG11347-RE | 0.030 | |
flfl | falafel | 0.030 | |
slpr | slipper | 0.030 | |
msl-3 | male-specific lethal 3 | 0.030 | |
Nsf2 | NEM-sensitive fusion protein 2 | 0.029 | |
Acsl | Acyl-CoA synthetase long-chain | 0.029 | |
gro | groucho | 0.029 | |
Atg18 | Autophagy-specific gene 18 | 0.028 | |
brk | brinker | 0.028 | |
nuf | nuclear fallout | 0.028 | |
zfh2 | Zn finger homeodomain 2 | 0.028 | |
rst | roughest | 0.028 | |
CG6051 | CG6051 gene product from transcript CG6051-RB | 0.028 | |
Dap160 | Dynamin associated protein 160 | 0.027 | |
msl-1 | male-specific lethal 1 | 0.027 | |
foxo | forkhead box, sub-group O | 0.027 | |
stet | stem cell tumor | 0.027 | |
EloA | Elongin A | 0.027 | |
dm | diminutive | 0.027 | |
oys | oysgedart | 0.026 | |
CG9940 | CG9940 gene product from transcript CG9940-RB | 0.026 | |
pll | pelle | 0.026 | |
aub | aubergine | 0.026 | |
Irk2 | Inwardly rectifying potassium channel 2 | 0.025 | |
Glut1 | Glucose transporter 1 | 0.025 | |
cic | capicua | 0.025 | |
Su(z)2 | Suppressor of zeste 2 | 0.025 | |
InR | Insulin-like receptor | 0.024 | |
Dhc64C | Dynein heavy chain 64C | 0.024 | |
tamo | CG4057 gene product from transcript CG4057-RA | 0.024 | |
Fak56D | Focal Adhesion Kinase | 0.023 | |
ns2 | nucleostemin 2 | 0.023 | |
LamC | Lamin C | 0.023 | |
CG8090 | CG8090 gene product from transcript CG8090-RB | 0.022 | |
stwl | stonewall | 0.022 | |
lkb1 | CG9374 gene product from transcript CG9374-RJ | 0.022 | |
CG10103 | CG10103 gene product from transcript CG10103-RA | 0.022 | |
CG30372 | CG30372 gene product from transcript CG30372-RC | 0.021 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
SMAD4 | SMAD family member 4 | 1.000 | |
SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 1.000 | |
SMAD2 | SMAD family member 2 | 0.999 | |
SMAD3 | SMAD family member 3 | 0.999 | |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.996 | |
TGFB1 | transforming growth factor, beta 1 | 0.992 | |
SMAD7 | SMAD family member 7 | 0.991 | |
BMPR1A | bone morphogenetic protein receptor, type IA | 0.978 | |
SNX6 | sorting nexin 6 | 0.975 | |
ABI2 | abl-interactor 2 | 0.952 | |
SMAD1 | SMAD family member 1 | 0.952 | |
ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.951 | |
SKIL | SKI-like oncogene | 0.940 | |
BMP2 | bone morphogenetic protein 2 | 0.938 | |
FSTL1 | follistatin-like 1 | 0.933 | |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.933 | |
TGFBR1 | transforming growth factor, beta receptor 1 | 0.857 | |
ADRB1 | adrenergic, beta-1-, receptor | 0.829 | |
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.819 | |
SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.761 | |
SMAD5 | SMAD family member 5 | 0.741 | |
TBX5 | T-box 5 | 0.711 | |
LIN7B | lin-7 homolog B (C. elegans) | 0.656 | |
ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.601 | |
JAG1 | jagged 1 | 0.596 | |
ENG | endoglin | 0.585 | |
ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.577 | |
SNX1 | sorting nexin 1 | 0.554 | |
CREBBP | CREB binding protein | 0.554 | |
TRIM33 | tripartite motif containing 33 | 0.545 | |
SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.542 | |
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.523 | |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.503 | |
TGFB3 | transforming growth factor, beta 3 | 0.483 | |
FKBP1A | FK506 binding protein 1A, 12kDa | 0.469 | |
AR | androgen receptor | 0.462 | |
WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.444 | |
RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.430 | |
FBLN1 | fibulin 1 | 0.426 | |
MAGEF1 | melanoma antigen family F, 1 | 0.422 | |
HIC1 | hypermethylated in cancer 1 | 0.412 | |
WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.378 | |
FHL2 | four and a half LIM domains 2 | 0.377 | |
PTK2 | PTK2 protein tyrosine kinase 2 | 0.357 | |
BMP1 | bone morphogenetic protein 1 | 0.354 | |
SNX9 | sorting nexin 9 | 0.354 | |
CAV2 | caveolin 2 | 0.343 | |
COL1A1 | collagen, type I, alpha 1 | 0.330 | |
NCK2 | NCK adaptor protein 2 | 0.317 | |
APOE | apolipoprotein E | 0.291 | |
SNX33 | sorting nexin 33 | 0.289 | |
COL8A1 | collagen, type VIII, alpha 1 | 0.271 | |
MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.265 | |
SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.230 | |
IGFBP3 | insulin-like growth factor binding protein 3 | 0.224 | |
LPXN | leupaxin | 0.213 | |
SH3D19 | SH3 domain containing 19 | 0.212 | |
SNW1 | SNW domain containing 1 | 0.211 | |
ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.208 | |
CXXC5 | CXXC finger protein 5 | 0.208 | |
MTMR4 | myotubularin related protein 4 | 0.205 | |
LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.203 | |
FN1 | fibronectin 1 | 0.182 | |
BCAR1 | breast cancer anti-estrogen resistance 1 | 0.174 | |
GDF5 | growth differentiation factor 5 | 0.170 | |
FZD1 | frizzled homolog 1 (Drosophila) | 0.169 | |
SNX2 | sorting nexin 2 | 0.161 | |
DLG1 | discs, large homolog 1 (Drosophila) | 0.161 | |
ZMYND11 | zinc finger, MYND-type containing 11 | 0.158 | |
MAPK8 | mitogen-activated protein kinase 8 | 0.150 | |
ACVR1 | activin A receptor, type I | 0.148 | |
RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.148 | |
PAX8 | paired box 8 | 0.146 | |
TRIP6 | thyroid hormone receptor interactor 6 | 0.146 | |
ADAM12 | ADAM metallopeptidase domain 12 | 0.136 | |
YY1 | YY1 transcription factor | 0.128 | |
RARA | retinoic acid receptor, alpha | 0.126 | |
ERBB2IP | erbb2 interacting protein | 0.119 | |
LIMD1 | LIM domains containing 1 | 0.115 | |
AQP1 | aquaporin 1 (Colton blood group) | 0.114 | |
DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.111 | |
DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.106 | |
CTGF | connective tissue growth factor | 0.104 | |
FNBP1 | formin binding protein 1 | 0.103 | |
WNT5A | wingless-type MMTV integration site family, member 5A | 0.102 | |
LRP6 | low density lipoprotein receptor-related protein 6 | 0.102 | |
PRKCDBP | protein kinase C, delta binding protein | 0.101 | |
TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.098 | |
TSC22D1 | TSC22 domain family, member 1 | 0.094 | |
DPT | dermatopontin | 0.093 | |
HEYL | hairy/enhancer-of-split related with YRPW motif-like | 0.092 | |
COL6A1 | collagen, type VI, alpha 1 | 0.092 | |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.092 | |
TGFB2 | transforming growth factor, beta 2 | 0.091 | |
GLIS2 | GLIS family zinc finger 2 | 0.090 | |
BMP7 | bone morphogenetic protein 7 | 0.088 | |
RANBP3 | RAN binding protein 3 | 0.086 | |
SGCE | sarcoglycan, epsilon | 0.083 | |
ZEB2 | zinc finger E-box binding homeobox 2 | 0.082 | |
PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.080 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Pmepa1 | prostate transmembrane protein, androgen induced 1 | 0.199 | |
Lamc1 | laminin, gamma 1 | 0.191 | |
Ednra | endothelin receptor type A | 0.156 | |
Dnaja1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.107 | |
Lum | lumican | 0.107 | |
Col8a1 | collagen, type VIII, alpha 1 | 0.106 | |
Elk3 | ELK3, ETS-domain protein | 0.099 | |
Slit3 | slit homolog 3 (Drosophila) | 0.097 | |
Flt1 | FMS-related tyrosine kinase 1 | 0.095 | |
Dlgap4 | discs, large homolog-associated protein 4 (Drosophila) | 0.088 | |
Fbln5 | fibulin 5 | 0.086 | |
Mmp23 | matrix metallopeptidase 23 | 0.085 | |
Ucp3 | uncoupling protein 3 (mitochondrial, proton carrier) | 0.081 | |
Pla1a | phospholipase A1 member A | 0.081 | |
Lyve1 | lymphatic vessel endothelial hyaluronan receptor 1 | 0.080 | |
Emp1 | epithelial membrane protein 1 | 0.074 | |
Kdr | kinase insert domain receptor | 0.071 | |
Gatad1 | GATA zinc finger domain containing 1 | 0.069 | |
Kcnj6 | potassium inwardly-rectifying channel, subfamily J, member 6 | 0.067 | |
Col4a4 | collagen, type IV, alpha 4 | 0.067 | |
Myh6 | myosin, heavy chain 6, cardiac muscle, alpha | 0.066 | |
Col5a1 | collagen, type V, alpha 1 | 0.065 | |
Jak1 | Janus kinase 1 | 0.063 | |
Agtr1a | angiotensin II receptor, type 1a | 0.059 | |
Smad7 | SMAD family member 7 | 0.058 | |
Slc6a17 | solute carrier family 6 (neurotransmitter transporter), member 17 | 0.058 | |
Hspd1 | heat shock protein 1 (chaperonin) | 0.054 | |
Fam198b | family with sequence similarity 198, member B | 0.054 | |
Mcam | melanoma cell adhesion molecule | 0.053 | |
Dpt | dermatopontin | 0.050 | |
Pygm | phosphorylase, glycogen, muscle | 0.048 | |
Stx12 | syntaxin 12 | 0.047 | |
Rhoj | ras homolog gene family, member J | 0.047 | |
Ddn | dendrin | 0.045 | |
Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.045 | |
Amd1 | adenosylmethionine decarboxylase 1 | 0.044 | |
Pdia4 | protein disulfide isomerase family A, member 4 | 0.044 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.044 | |
Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.044 | |
Hspa13 | heat shock protein 13 | 0.043 | |
Degs1 | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 0.043 | |
Baiap2 | BAI1-associated protein 2 | 0.042 | |
Eltd1 | EGF, latrophilin and seven transmembrane domain containing 1 | 0.042 | |
Col4a1 | collagen, type IV, alpha 1 | 0.041 | |
Clec11a | C-type lectin domain family 11, member a | 0.041 | |
Rims1 | regulating synaptic membrane exocytosis 1 | 0.041 | |
Tcf4 | transcription factor 4 | 0.040 | |
Prkch | protein kinase C, eta | 0.040 | |
Dlgap3 | discs, large (Drosophila) homolog-associated protein 3 | 0.039 | |
Slc22a6 | solute carrier family 22 (organic anion transporter), member 6 | 0.039 | |
Lox | lysyl oxidase | 0.039 | |
Calca | calcitonin-related polypeptide alpha | 0.039 | |
Angpt4 | angiopoietin 4 | 0.039 | |
RGD1311307 | similar to 1300014I06Rik protein | 0.039 | |
Becn1 | beclin 1, autophagy related | 0.039 | |
Fgfr1 | Fibroblast growth factor receptor 1 | 0.038 | |
Pfkfb3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.038 | |
Plac9 | placenta-specific 9 | 0.036 | |
Scn8a | sodium channel, voltage gated, type VIII, alpha subunit | 0.036 | |
Snrk | SNF related kinase | 0.036 | |
Spata9 | spermatogenesis associated 9 | 0.035 | |
Dock6 | dedicator of cytokinesis 6 | 0.035 | |
Cish | cytokine inducible SH2-containing protein | 0.035 | |
Sc65 | synaptonemal complex protein SC65 | 0.035 | |
Lmcd1 | LIM and cysteine-rich domains 1 | 0.035 | |
Hsp90b1 | heat shock protein 90, beta, member 1 | 0.034 | |
Loxl1 | lysyl oxidase-like 1 | 0.034 | |
Il24 | interleukin 24 | 0.034 | |
Mfap5 | microfibrillar associated protein 5 | 0.034 | |
Eif4ebp2 | eukaryotic translation initiation factor 4E binding protein 2 | 0.034 | |
Dchs1 | dachsous 1 (Drosophila) | 0.034 | |
Tgfb3 | transforming growth factor, beta 3 | 0.033 | |
RT1-M4 | RT1 class Ib, locus M4 | 0.033 | |
Ddx1 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 0.033 | |
Hat1 | histone acetyltransferase 1 | 0.032 | |
Mafb | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) | 0.032 | |
Vegfc | vascular endothelial growth factor C | 0.032 | |
RGD1307396 | similar to RIKEN cDNA 6330406I15 | 0.032 | |
Hapln2 | hyaluronan and proteoglycan link protein 2 | 0.032 | |
Cdh5 | cadherin 5 | 0.031 | |
Aldh3a1 | aldehyde dehydrogenase 3 family, member A1 | 0.031 | |
Pdcl | phosducin-like | 0.031 | |
LOC680988 | similar to ribosomal protein S12 | 0.031 | |
Jak2 | Janus kinase 2 | 0.031 | |
Mgll | monoglyceride lipase | 0.031 | |
Notch2 | Notch homolog 2 (Drosophila) | 0.031 | |
Timp3 | TIMP metallopeptidase inhibitor 3 | 0.030 | |
Gsk3b | glycogen synthase kinase 3 beta | 0.030 | |
Atxn2 | ataxin 2 | 0.030 | |
Hipk3 | homeodomain interacting protein kinase 3 | 0.030 | |
Efnb1 | ephrin B1 | 0.030 | |
Lrp1 | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 0.030 | |
Aipl1 | aryl hydrocarbon receptor-interacting protein-like 1 | 0.029 | |
Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.029 | |
Osr2 | odd-skipped related 2 (Drosophila) | 0.029 | |
Megf6 | multiple EGF-like-domains 6 | 0.028 | |
Mustn1 | musculoskeletal, embryonic nuclear protein 1 | 0.028 | |
Srrm2 | serine/arginine repetitive matrix 2 | 0.028 | |
Gpr116 | G protein-coupled receptor 116 | 0.028 | |
Folh1 | folate hydrolase 1 | 0.028 |