The network for 'compound eye development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

compound eye development

The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.

Mus musculus
Name Description Probability Func Analog Organism
Notch1 Notch gene homolog 1 (Drosophila) 0.994
Hes1 hairy and enhancer of split 1 (Drosophila) 0.979
Gli3 GLI-Kruppel family member GLI3 0.936
Dll1 delta-like 1 (Drosophila) 0.924
Emx1 empty spiracles homolog 1 (Drosophila) 0.914
Pitx2 paired-like homeodomain transcription factor 2 0.911
Prrx1 paired related homeobox 1 0.904
Shh sonic hedgehog 0.879
Foxc1 forkhead box C1 0.877
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.825
Cdon cell adhesion molecule-related/down-regulated by oncogenes 0.804
Eya1 eyes absent 1 homolog (Drosophila) 0.789
Foxg1 forkhead box G1 0.788
Gli2 GLI-Kruppel family member GLI2 0.746
Tnf tumor necrosis factor 0.742
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.698
Msx2 homeobox, msh-like 2 0.692
Apc adenomatosis polyposis coli 0.684
Hes5 hairy and enhancer of split 5 (Drosophila) 0.648
Emx2 empty spiracles homolog 2 (Drosophila) 0.633
Pax2 paired box gene 2 0.625
Fgfr1 fibroblast growth factor receptor 1 0.621
Jag2 jagged 2 0.605
Socs1 suppressor of cytokine signaling 1 0.598
Enah enabled homolog (Drosophila) 0.560
Fgf8 fibroblast growth factor 8 0.557
Ric8 resistance to inhibitors of cholinesterase 8 homolog (C. elegans) 0.554
Cpeb3 cytoplasmic polyadenylation element binding protein 3 0.525
Jun Jun oncogene 0.523
Pax3 paired box gene 3 0.517
Gbp5 guanylate binding protein 5 0.515
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.514
Twist2 twist homolog 2 (Drosophila) 0.512
Psen1 presenilin 1 0.512
Atp11c ATPase, class VI, type 11C 0.496
Ntf3 neurotrophin 3 0.495
Set SET nuclear oncogene 0.493
Gata3 GATA binding protein 3 0.490
Otx2 orthodenticle homolog 2 (Drosophila) 0.480
Meox2 mesenchyme homeobox 2 0.480
Casp1 caspase 1 0.460
Nog noggin 0.455
Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.446
Ikzf1 IKAROS family zinc finger 1 0.439
Egr2 early growth response 2 0.431
Pbx1 pre B-cell leukemia transcription factor 1 0.428
Gsc goosecoid homeobox 0.421
Uncx UNC homeobox 0.420
Ncoa3 nuclear receptor coactivator 3 0.414
En1 engrailed 1 0.413
Pycard PYD and CARD domain containing 0.385
Arpc4 actin related protein 2/3 complex, subunit 4 0.371
Apbb1ip amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.369
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.353
Cbl Casitas B-lineage lymphoma 0.350
Chd7 chromodomain helicase DNA binding protein 7 0.344
Il2rg interleukin 2 receptor, gamma chain 0.344
Dlx1 distal-less homeobox 1 0.339
Pip5k1c phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma 0.333
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.330
Egr1 early growth response 1 0.321
Hoxa2 homeobox A2 0.310
Hif1a hypoxia inducible factor 1, alpha subunit 0.305
Hoxd13 homeobox D13 0.304
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.302
Boc biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein 0.302
Efs embryonal Fyn-associated substrate 0.300
Tcfap2a transcription factor AP-2, alpha 0.300
Aim2 absent in melanoma 2 0.294
Rb1 retinoblastoma 1 0.291
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.288
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.278
Tcfap2c transcription factor AP-2, gamma 0.269
Mll1 myeloid/lymphoid or mixed-lineage leukemia 1 0.261
Emid2 EMI domain containing 2 0.258
Egfr epidermal growth factor receptor 0.256
Hoxa1 homeobox A1 0.251
Lhx9 LIM homeobox protein 9 0.250
Ptk7 PTK7 protein tyrosine kinase 7 0.248
Ikbkg inhibitor of kappaB kinase gamma 0.244
Isl1 ISL1 transcription factor, LIM/homeodomain 0.239
Setdb1 SET domain, bifurcated 1 0.238
Plagl2 pleiomorphic adenoma gene-like 2 0.238
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.236
Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 0.236
Foxn1 forkhead box N1 0.235
Hand2 heart and neural crest derivatives expressed transcript 2 0.233
Ptprc protein tyrosine phosphatase, receptor type, C 0.228
Auts2 autism susceptibility candidate 2 0.228
Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.228
Hoxa3 homeobox A3 0.226
Sh2b1 SH2B adaptor protein 1 0.222
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.220
Arid1a AT rich interactive domain 1A (SWI-like) 0.220
Ret ret proto-oncogene 0.215
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.213
Foxc2 forkhead box C2 0.213
Ikbkb inhibitor of kappaB kinase beta 0.206
Dach1 dachshund 1 (Drosophila) 0.206
Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 0.204
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
otx2 orthodenticle homolog 2 0.905
dla deltaA 0.851
dlc deltaC 0.804
dld deltaD 0.784
cdh2 cadherin 2, neuronal 0.741
her1 hairy-related 1 0.666
pea3 ETS-domain transcription factor pea3 0.578
pax6b paired box gene 6b 0.576
fgf3 fibroblast growth factor 3 0.518
otpb orthopedia homolog b 0.518
nkx6.2 NK6 transcription factor related, locus 2 0.513
wt1b wilms tumor 1b 0.470
isl1 islet1 0.459
irx4b iroquois homeobox protein 4b 0.447
sox1a SRY-box containing gene 1a 0.433
spaw southpaw 0.405
notch1a notch homolog 1a 0.402
fgfr4 fibroblast growth factor receptor 4 0.400
socs3a suppressor of cytokine signaling 3a 0.366
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.362
wnt5b wingless-type MMTV integration site family, member 5b 0.358
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.358
pax8 paired box gene 8 0.353
il7r interleukin 7 receptor 0.350
tfr1a transferrin receptor 1a 0.339
pdlim4 PDZ and LIM domain 4 0.339
lrrc50 leucine rich repeat containing 50 0.332
ripply2 ripply2 0.330
cdx4 caudal type homeo box transcription factor 4 0.328
sox3 SRY-box containing gene 3 0.324
pdlim7 PDZ and LIM domain 7 0.310
insm1b insulinoma-associated 1b 0.306
six4b sine oculis homeobox homolog 4b 0.304
cbfb core-binding factor, beta subunit 0.301
wnt1 wingless-type MMTV integration site family, member 1 0.299
foxn4 forkhead box N4 0.297
pitx3 paired-like homeodomain transcription factor 3 0.288
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.286
sesn1 sestrin 1 0.280
emx1 empty spiracles homeobox 1 0.279
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.275
hmx4 H6 family homeobox 4 0.270
etv2 ets variant gene 2 0.270
zgc:112211 zgc:112211 0.264
gbx2 gastrulation brain homeo box 2 0.263
her8a hairy-related 8a 0.263
six4a sine oculis homeobox homolog 4a 0.262
mespb mesoderm posterior b 0.257
dlx4a distal-less homeobox gene 4a 0.248
erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a 0.234
wnt11 wingless-type MMTV integration site family, member 11 0.231
rx3 retinal homeobox gene 3 0.231
ndr2 nodal-related 2 0.230
irx3a iroquois homeobox protein 3a 0.220
six2a sine oculis-related homeobox 2a 0.216
hoxb1b homeo box B1b 0.216
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.213
foxg1a forkhead box G1a 0.211
gli2a GLI-Kruppel family member GLI2a 0.211
limk2 LIM domain kinase 2 0.210
gadd45bb growth arrest and DNA-damage-inducible, beta b 0.208
tmprss4a transmembrane protease, serine 4a 0.206
msgn1 mesogenin 1 0.203
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.196
socs3b suppressor of cytokine signaling 3b 0.190
pcdh8 protocadherin 8 0.189
nrg1 neuregulin 1 0.188
ighm immunoglobulin heavy constant mu and immunoglobulin heavy constant mu 0.188
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.184
shhb sonic hedgehog b 0.181
tbx22 T-box 22 0.181
acsl4a acyl-CoA synthetase long-chain family member 4a 0.179
limk1 LIM domain kinase 1 0.177
bmp4 bone morphogenetic protein 4 0.172
hnf1bb HNF1 homeobox Bb 0.172
sox19a SRY-box containing gene 19a 0.172
chd7 chromodomain helicase DNA binding protein 7 0.171
stap2a signal transducing adaptor family member 2a 0.169
dlb deltaB 0.169
rarab retinoic acid receptor, alpha b 0.168
spsb4a splA/ryanodine receptor domain and SOCS box containing 4a 0.166
ripply1 ripply1 0.163
olig2 oligodendrocyte lineage transcription factor 2 0.162
card14 caspase recruitment domain family, member 14 0.158
tbr1b T-box, brain, 1b 0.157
hlxb9lb homeo box HB9 like b 0.156
flh floating head 0.155
si:ch211-232m7.1 si:ch211-232m7.1 0.154
tlx2 T-cell leukemia, homeobox 2 0.153
esyt3 extended synaptotagmin-like protein 3 0.152
tmem88a transmembrane protein 88 a 0.150
gyltl1b glycosyltransferase-like 1b 0.148
junbl jun B proto-oncogene, like 0.147
pdlim2 PDZ and LIM domain 2 (mystique) 0.147
coe2 coe2 0.146
tbx16 T-box gene 16 0.146
her6 hairy-related 6 0.144
jag1a jagged 1a 0.144
hhex hematopoietically expressed homeobox 0.143
hoxa9a homeo box A9a 0.140
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Drosophila melanogaster
Name Description Probability Func Analog Organism
E(spl) Enhancer of split 0.998
yki yorkie 0.995
Nrt Neurotactin 0.994
eyg eyegone 0.992
trio CG18214 gene product from transcript CG18214-RA 0.991
ttk tramtrack 0.991
hbs hibris 0.988
cno canoe 0.987
dos daughter of sevenless 0.985
nmo nemo 0.984
sev sevenless 0.983
argos CG4531 gene product from transcript CG4531-RA 0.983
Gug Grunge 0.983
so sine oculis 0.982
sina seven in absentia 0.977
hpo hippo 0.976
phyl phyllopod 0.976
msn misshapen 0.974
Rac1 CG2248 gene product from transcript CG2248-RA 0.970
spen split ends 0.970
cutlet CG33122 gene product from transcript CG33122-RA 0.970
HLHm7 E(spl) region transcript m7 0.964
hipk homeodomain interacting protein kinase 0.962
sens senseless 0.961
Tom Twin of m4 0.961
sty sprouty 0.960
eya eyes absent 0.960
phl pole hole 0.959
Ser Serrate 0.956
ey eyeless 0.954
Cdc42 CG12530 gene product from transcript CG12530-RA 0.954
ebi CG4063 gene product from transcript CG4063-RA 0.953
Peb Protein ejaculatory bulb 0.952
Vang Van Gogh 0.951
Kap-alpha3 karyopherin alpha3 0.936
Moe Moesin 0.936
ds dachsous 0.933
shi shibire 0.932
ato atonal 0.930
Akt1 CG4006 gene product from transcript CG4006-RA 0.930
tkv thickveins 0.925
wts warts 0.924
dac dachshund 0.923
S6kII RPS6-protein kinase-II 0.921
ro rough 0.920
N Notch 0.916
fz frizzled 0.915
bif bifocal 0.906
sv shaven 0.905
Egfr Epidermal growth factor receptor 0.903
amos absent MD neurons and olfactory sensilla 0.896
Ten-m Tenascin major 0.896
dsh dishevelled 0.895
Dl Delta 0.895
Rab11 Rab-protein 11 0.894
crb crumbs 0.892
esg escargot 0.888
sd scalloped 0.888
frc fringe connection 0.883
sna snail 0.880
Mi-2 CG8103 gene product from transcript CG8103-RA 0.865
sax saxophone 0.861
cindr CIN85 and CD2AP orthologue 0.859
ac achaete 0.859
Su(Tpl) CG32217 gene product from transcript CG32217-RB 0.856
tsh teashirt 0.856
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.854
mam mastermind 0.854
csw corkscrew 0.843
CG11347 CG11347 gene product from transcript CG11347-RE 0.840
fj four-jointed 0.836
lqf liquid facets 0.828
C3G CG42328 gene product from transcript CG42328-RC 0.828
Dsor1 Downstream of raf1 0.825
pyd polychaetoid 0.825
HLHmdelta E(spl) region transcript mdelta 0.824
emc extra macrochaetae 0.823
ex expanded 0.823
caup caupolican 0.822
Mer Merlin 0.821
Gap1 GTPase-activating protein 1 0.815
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.812
opa odd paired 0.808
klu klumpfuss 0.807
rok Rho-kinase 0.798
Rme-8 Receptor mediated endocytosis 8 0.793
trc tricornered 0.793
Hop Hsp70/Hsp90 organizing protein homolog 0.792
X11L CG5675 gene product from transcript CG5675-RB 0.790
wg wingless 0.783
m4 E(spl) region transcript m4 0.781
hep hemipterous 0.778
fng fringe 0.767
Atx-1 Ataxin 1 0.764
bdg bedraggled 0.752
ninaE neither inactivation nor afterpotential E 0.750
Rala Ras-related protein 0.750
sca scabrous 0.739
ci cubitus interruptus 0.732
RASSF8 CG5053 gene product from transcript CG5053-RA 0.729
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Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 0.992
JUN jun proto-oncogene 0.962
FUS fused in sarcoma 0.940
ATXN1 ataxin 1 0.922
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.913
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.900
NOTCH1 notch 1 0.895
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.892
GRB2 growth factor receptor-bound protein 2 0.882
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.824
CFL1 cofilin 1 (non-muscle) 0.779
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.776
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.764
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.725
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.681
LMO4 LIM domain only 4 0.671
ANAPC5 anaphase promoting complex subunit 5 0.637
APP amyloid beta (A4) precursor protein 0.615
EGR1 early growth response 1 0.582
NOTCH3 notch 3 0.555
NFYA nuclear transcription factor Y, alpha 0.539
RAP1A RAP1A, member of RAS oncogene family 0.535
DUSP1 dual specificity phosphatase 1 0.531
ELF4 E74-like factor 4 (ets domain transcription factor) 0.519
FOS FBJ murine osteosarcoma viral oncogene homolog 0.510
BCR breakpoint cluster region 0.508
JAG1 jagged 1 0.476
SOCS3 suppressor of cytokine signaling 3 0.469
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.454
NLRC4 NLR family, CARD domain containing 4 0.450
FBXO7 F-box protein 7 0.449
IRF2BP1 interferon regulatory factor 2 binding protein 1 0.440
JUB jub, ajuba homolog (Xenopus laevis) 0.422
RIN1 Ras and Rab interactor 1 0.413
ITSN1 intersectin 1 (SH3 domain protein) 0.406
ATN1 atrophin 1 0.406
WDR5 WD repeat domain 5 0.400
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.389
JUND jun D proto-oncogene 0.361
LIMD1 LIM domains containing 1 0.336
UBA1 ubiquitin-like modifier activating enzyme 1 0.333
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.332
BMP1 bone morphogenetic protein 1 0.325
TNRC6A trinucleotide repeat containing 6A 0.323
MAPK8 mitogen-activated protein kinase 8 0.322
RAB14 RAB14, member RAS oncogene family 0.318
BAIAP2 BAI1-associated protein 2 0.298
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.292
LRDD leucine-rich repeats and death domain containing 0.290
GSK3B glycogen synthase kinase 3 beta 0.285
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.281
FOSL1 FOS-like antigen 1 0.277
SMAD1 SMAD family member 1 0.276
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.267
LDOC1 leucine zipper, down-regulated in cancer 1 0.262
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.258
MAML1 mastermind-like 1 (Drosophila) 0.254
ARFIP2 ADP-ribosylation factor interacting protein 2 0.243
FAT1 FAT tumor suppressor homolog 1 (Drosophila) 0.243
JUNB jun B proto-oncogene 0.240
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.231
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.230
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.229
RIPK2 receptor-interacting serine-threonine kinase 2 0.222
RCHY1 ring finger and CHY zinc finger domain containing 1 0.220
EP300 E1A binding protein p300 0.217
RUNX1 runt-related transcription factor 1 0.216
SH3KBP1 SH3-domain kinase binding protein 1 0.213
CDC16 cell division cycle 16 homolog (S. cerevisiae) 0.206
TNRC6B trinucleotide repeat containing 6B 0.205
RBBP5 retinoblastoma binding protein 5 0.197
RLIM ring finger protein, LIM domain interacting 0.195
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.191
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.185
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.183
CDK2 cyclin-dependent kinase 2 0.183
STAT5A signal transducer and activator of transcription 5A 0.180
PGR progesterone receptor 0.175
TSC22D1 TSC22 domain family, member 1 0.168
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.167
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.159
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.154
CREBBP CREB binding protein 0.153
GMFB glia maturation factor, beta 0.152
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.152
NUAK1 NUAK family, SNF1-like kinase, 1 0.150
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.149
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.149
ATF3 activating transcription factor 3 0.148
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.147
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.146
RB1 retinoblastoma 1 0.144
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.141
DCAF7 DDB1 and CUL4 associated factor 7 0.141
PRRC2C proline-rich coiled-coil 2C 0.141
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.140
AIG1 androgen-induced 1 0.138
SOCS1 suppressor of cytokine signaling 1 0.136
TOX4 TOX high mobility group box family member 4 0.133
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 0.132
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism