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Drosophila melanogaster

17 genes annotated in fly

g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger" (in gray)

Name	Description	Probability	Func Analog Organism
CG42629	CG42629 gene product from transcript CG42629-RB	0.625
mtt	mangetout	0.307
PIP5K59B	CG3682 gene product from transcript CG3682-RE	0.288
TyrR	Tyramine receptor	0.287
5-HT1A	Serotonin receptor 1A	0.260
Nmdar1	NMDA receptor 1	0.234
Mkp3	Mitogen-activated protein kinase phosphatase 3	0.222
dnc	dunce	0.220
CG13253	CG13253 gene product from transcript CG13253-RB	0.183
Ank2	Ankyrin 2	0.166
Mad	Mothers against dpp	0.141
Clk	Clock	0.140
Ac3	CG1506 gene product from transcript CG1506-RA	0.134
NPFR1	neuropeptide F receptor	0.127
dnr1	defense repressor 1	0.127
Tbh	Tyramine beta hydroxylase	0.120
tim	timeless	0.119
Atf-2	Activating transcription factor-2	0.113
Pde8	Phosphodiesterase 8	0.107
Dat	Dopamine N acetyltransferase	0.106
RanBPM	Ran-binding protein M	0.105
per	period	0.096
CG18437	CG18437 gene product from transcript CG18437-RB	0.095
CG32813	CG32813 gene product from transcript CG32813-RE	0.092
Glut1	Glucose transporter 1	0.088
Octbeta2R	CG33976 gene product from transcript CG33976-RA	0.083
unc79	CG5237 gene product from transcript CG5237-RB	0.079
l(3)82Fd	CG32464 gene product from transcript CG32464-RR	0.078
Eip63F-1	Ecdysone-induced protein 63F 1	0.072
CRMP	Collapsin Response Mediator Protein	0.072
dhd	deadhead	0.072
Gr28b	Gustatory receptor 28b	0.065
cngl	CNG channel-like	0.065
Dsk	Drosulfakinin	0.062
5-HT1B	Serotonin receptor 1B	0.058
Corin	CG2105 gene product from transcript CG2105-RB	0.057
dpr20	CG12191 gene product from transcript CG12191-RA	0.054
Pdp1	PAR-domain protein 1	0.054
nord	CG30418 gene product from transcript CG30418-RA	0.050
ppk	pickpocket	0.048
ClC-a	Chloride channel-a	0.045
CG34400	CG34400 gene product from transcript CG34400-RD	0.043
rho	rhomboid	0.042
eys	eyes shut	0.042
Hs3st-A	Heparan sulfate 3-O sulfotransferase-A	0.040
sty	sprouty	0.040
norpA	no receptor potential A	0.038
Gr43a	Gustatory receptor 43a	0.037
CG14274	CG14274 gene product from transcript CG14274-RA	0.037
mol	moladietz	0.036
fd85E	forkhead domain 85E	0.036
Ast-C	Allatostatin C	0.036
GluRIIA	Glutamate receptor IIA	0.034
KCNQ	KCNQ potassium channel	0.034
unc-13-4A	CG32381 gene product from transcript CG32381-RB	0.033
Nha2	Na[+]/H[+] hydrogen antiporter 2	0.032
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	0.032
CG34393	CG34393 gene product from transcript CG34393-RA	0.032
CG34347	CG34347 gene product from transcript CG34347-RB	0.032
foxo	forkhead box, sub-group O	0.032
CG15479	CG15479 gene product from transcript CG15479-RA	0.031
oa2	octopamine receptor 2	0.030
Cpr92A	Cuticular protein 92A	0.030
CG14459	CG14459 gene product from transcript CG14459-RB	0.029
CG14160	CG14160 gene product from transcript CG14160-RA	0.029
Ptp99A	Protein tyrosine phosphatase 99A	0.028
CG14545	CG14545 gene product from transcript CG14545-RA	0.027
beat-Vb	CG31298 gene product from transcript CG31298-RA	0.027
Vsx2	CG33980 gene product from transcript CG33980-RA	0.027
Ilp3	Insulin-like peptide 3	0.027
Gyc76C	Guanylyl cyclase at 76C	0.026
Dh44-R1	Diuretic hormone 44 receptor 1	0.026	Human Rat
CG31999	CG31999 gene product from transcript CG31999-RA	0.026
CG33696	CG33696 gene product from transcript CG33696-RA	0.026
Socs36E	Suppressor of cytokine signaling at 36E	0.026
Nmdar2	NMDA receptor 2	0.026
E(Pc)	Enhancer of Polycomb	0.025
Spf45	CG17540 gene product from transcript CG17540-RB	0.025
mAcR-60C	muscarinic Acetylcholine Receptor 60C	0.025	Mouse
AR-2	Allatostatin Receptor 2	0.024
Pde6	Phosphodiesterase 6	0.024
Sox100B	CG15552 gene product from transcript CG15552-RA	0.024
SIFR	SIFamide receptor	0.024
CG15088	CG15088 gene product from transcript CG15088-RC	0.023
bin	biniou	0.023
CG14570	CG14570 gene product from transcript CG14570-RA	0.023
Lcp65Ag1	CG10530 gene product from transcript CG10530-RA	0.022
CG9447	CG9447 gene product from transcript CG9447-RB	0.022
stet	stem cell tumor	0.022
CG12851	CG12851 gene product from transcript CG12851-RB	0.022
D2R	Dopamine 2-like receptor	0.021	Human Mouse Rat
Ric	Ras which interacts with Calmodulin	0.021
CG10858	CG10858 gene product from transcript CG10858-RB	0.021
GABA-B-R3	metabotropic GABA-B receptor subtype 3	0.021
Cpr72Eb	Cuticular protein 72Eb	0.021
CG1909	CG1909 gene product from transcript CG1909-RA	0.021
CG16778	CG16778 gene product from transcript CG16778-RA	0.021
Tre1	trapped in endoderm-1	0.021
CG5386	CG5386 gene product from transcript CG5386-RA	0.021
beat-Ic	beaten path Ic	0.021
5-HT7	Serotonin receptor 7	0.020
CG31191	CG31191 gene product from transcript CG31191-RA	0.020
Dms	Dromyosuppressin	0.020
Gr64e	Gustatory receptor 64e	0.020
CG13579	CG13579 gene product from transcript CG13579-RA	0.020
jeb	jelly belly	0.020
CG4239	CG4239 gene product from transcript CG4239-RA	0.020
2mit	CG42573 gene product from transcript CG42573-RA	0.020
flower	CG6151 gene product from transcript CG6151-RA	0.020
Frq2	Frequenin 2	0.019
os	outstretched	0.019
ens	ensconsin	0.019
CG11317	CG11317 gene product from transcript CG11317-RA	0.019
CG15153	CG15153 gene product from transcript CG15153-RA	0.019
CcapR	Cardioacceleratory peptide receptor	0.019
CG9059	CG9059 gene product from transcript CG9059-RD	0.019
DmsR-2	Dromyosuppressin receptor 2	0.019
endoB	endophilin B	0.018
stg1	stargazin-like protein	0.018
capaR	capa receptor	0.018
amon	amontillado	0.018
CG32206	CG32206 gene product from transcript CG32206-RB	0.018
CG7708	CG7708 gene product from transcript CG7708-RA	0.018
Act57B	Actin 57B	0.018
form3	formin 3	0.018
CG7191	CG7191 gene product from transcript CG7191-RA	0.018
Sgs8	Salivary gland secretion 8	0.018
pHCl	CG33989 gene product from transcript CG33989-RD	0.018
Ir76b	Ionotropic receptor 76b	0.018
CG17341	CG17341 gene product from transcript CG17341-RA	0.017
CG8888	CG8888 gene product from transcript CG8888-RA	0.017
cic	capicua	0.017
laza	lazaro	0.017
Nep3	Neprilysin 3	0.017
Or94b	Odorant receptor 94b	0.017
dmrt99B	doublesex-Mab related 99B	0.017
Nhe2	Na[+]/H[+] hydrogen exchanger 2	0.017
CG14086	CG14086 gene product from transcript CG14086-RB	0.017
GluRIIB	Glutamate receptor IIB	0.017
Fer2	48 related 2	0.017
luna	CG33473 gene product from transcript CG33473-RB	0.017
Ac78C	Adenylyl cyclase 78C	0.017	Rat
bap	bagpipe	0.016
beta4GalNAcTA	CG8536 gene product from transcript CG8536-RA	0.016
AdoR	Adenosine receptor	0.016
Ir47a	Ionotropic receptor 47a	0.016
Takr99D	Tachykinin-like receptor at 99D	0.016
CG6282	CG6282 gene product from transcript CG6282-RC	0.016
CG7431	CG7431 gene product from transcript CG7431-RA	0.016	Fly
CG14416	CG14416 gene product from transcript CG14416-RA	0.016
trpgamma	CG5996 gene product from transcript CG5996-RB	0.016
ppk7	pickpocket 7	0.016
lin-28	CG17334 gene product from transcript CG17334-RA	0.015
CG12402	CG12402 gene product from transcript CG12402-RA	0.015
edl	ETS-domain lacking	0.015
CG33203	CG33203 gene product from transcript CG33203-RB	0.015
to	takeout	0.015
stl	stall	0.015
GluRIIE	Glutamate receptor IIE	0.015
CG7053	CG7053 gene product from transcript CG7053-RA	0.015
CG11221	CG11221 gene product from transcript CG11221-RA	0.015
zpg	zero population growth	0.015
CG5621	CG5621 gene product from transcript CG5621-RA	0.015
CCKLR-17D3	CCK-like receptor at 17D3	0.015
dpr18	CG14948 gene product from transcript CG14948-RA	0.015
tey	teyrha-meyrha	0.015
Or69a	Odorant receptor 69a	0.015
CG16718	CG16718 gene product from transcript CG16718-RA	0.015
Rdl	Resistant to dieldrin	0.014
CG3921	CG3921 gene product from transcript CG3921-RA	0.014
CG12541	CG12541 gene product from transcript CG12541-RD	0.014
CG34381	CG34381 gene product from transcript CG34381-RB	0.014
dpr5	CG5308 gene product from transcript CG5308-RA	0.014
repo	reversed polarity	0.014
Gr8a	Gustatory receptor 8a	0.014
Rbp9	RNA-binding protein 9	0.014
cry	cryptochrome	0.014
CG5768	CG5768 gene product from transcript CG5768-RB	0.014
CG13724	CG13724 gene product from transcript CG13724-RA	0.014
Gr43b	CG1339 gene product from transcript CG1339-RA	0.014
CG15253	CG15253 gene product from transcript CG15253-RA	0.014
CG30158	CG30158 gene product from transcript CG30158-RA	0.014
beat-IV	CG10152 gene product from transcript CG10152-RA	0.014
CG13424	CG13424 gene product from transcript CG13424-RA	0.014
dpr3	CG33516 gene product from transcript CG33516-RB	0.014
CG42513	CG42513 gene product from transcript CG42513-RB	0.014
CG3822	CG3822 gene product from transcript CG3822-RA	0.014
RunxA	CG34145 gene product from transcript CG34145-RA	0.014
CG5361	CG5361 gene product from transcript CG5361-RA	0.014
CG14089	CG14089 gene product from transcript CG14089-RA	0.014
CG11071	CG11071 gene product from transcript CG11071-RA	0.014
Ir85a	Ionotropic receptor 85a	0.013
Ef1alpha48D	Elongation factor 1alpha48D	0.013
CG4678	CG4678 gene product from transcript CG4678-RE	0.013
CG1688	CG1688 gene product from transcript CG1688-RA	0.013
orb	oo18 RNA-binding protein	0.013
LpR1	CG31094 gene product from transcript CG31094-RJ	0.013
Ipk1	CG30295 gene product from transcript CG30295-RB	0.013
CG14669	CG14669 gene product from transcript CG14669-RA	0.013
CG12194	CG12194 gene product from transcript CG12194-RA	0.013
Osi22	Osiris 22	0.013
Or59b	Odorant receptor 59b	0.013
CG15765	CG15765 gene product from transcript CG15765-RA	0.013
Ilp4	Insulin-like peptide 4	0.013
Ca-alpha1T	CG15899 gene product from transcript CG15899-RC	0.013
CG17321	CG17321 gene product from transcript CG17321-RA	0.013
CG34362	CG34362 gene product from transcript CG34362-RD	0.013
CG5160	CG5160 gene product from transcript CG5160-RA	0.012
CG6106	CG6106 gene product from transcript CG6106-RA	0.012
Pde1c	Phosphodiesterase 1c	0.012
CG3081	CG3081 gene product from transcript CG3081-RA	0.012
CG31219	CG31219 gene product from transcript CG31219-RA	0.012
CG34139	CG34139 gene product from transcript CG34139-RD	0.012
CG17364	CG17364 gene product from transcript CG17364-RA	0.012
CG10830	CG10830 gene product from transcript CG10830-RA	0.012
OdsH	Ods-site homeobox	0.012
CG14244	CG14244 gene product from transcript CG14244-RB	0.012
CG14565	CG14565 gene product from transcript CG14565-RA	0.012
CG7248	CG7248 gene product from transcript CG7248-RA	0.012
CG17105	CG17105 gene product from transcript CG17105-RA	0.012
CG3635	CG3635 gene product from transcript CG3635-RB	0.012
Rgk3	CG34397 gene product from transcript CG34397-RC	0.012
Cyp308a1	CG6585 gene product from transcript CG6585-RA	0.012
Ir7a	Ionotropic receptor 7a	0.012
inaE	inactivation no afterpotential E	0.012
CG3713	CG3713 gene product from transcript CG3713-RA	0.012
CG8641	CG8641 gene product from transcript CG8641-RA	0.012
CG30181	CG30181 gene product from transcript CG30181-RA	0.012
Muc91C	Mucin 91C	0.012
CG12826	CG12826 gene product from transcript CG12826-RA	0.012
AlCR2	allatostatin C receptor 2	0.012	Rat
CG10804	CG10804 gene product from transcript CG10804-RB	0.012
CG14082	CG14082 gene product from transcript CG14082-RB	0.012
spz4	spatzle 4	0.012
CG16800	CG16800 gene product from transcript CG16800-RB	0.012
CG4459	CG4459 gene product from transcript CG4459-RA	0.012
AlstR	Allatostatin Receptor	0.012
CG13712	CG13712 gene product from transcript CG13712-RA	0.012
Task6	CG9637 gene product from transcript CG9637-RC	0.012
Hey	Hairy/E(spl)-related with YRPW motif	0.012
Scr	Sex combs reduced	0.011
CG6462	CG6462 gene product from transcript CG6462-RA	0.011
CG13408	CG13408 gene product from transcript CG13408-RA	0.011
CG5079	CG5079 gene product from transcript CG5079-RA	0.011
CG11768	CG11768 gene product from transcript CG11768-RB	0.011
CG9395	CG9395 gene product from transcript CG9395-RB	0.011
Gadd45	CG11086 gene product from transcript CG11086-RA	0.011
dpr15	CG10095 gene product from transcript CG10095-RA	0.011
pgc	polar granule component	0.011
sick	sickie	0.011
CG12029	CG12029 gene product from transcript CG12029-RB	0.011
CG13563	CG13563 gene product from transcript CG13563-RB	0.011
Vsx1	CG4136 gene product from transcript CG4136-RA	0.011
klg	klingon	0.011
rtGEF	rho-type guanine exchange factor	0.011
p38b	CG7393 gene product from transcript CG7393-RA	0.011
CG14340	CG14340 gene product from transcript CG14340-RA	0.011
CG34375	CG34375 gene product from transcript CG34375-RA	0.011
Shaw	Shaker cognate w	0.011
CG14358	CG14358 gene product from transcript CG14358-RB	0.011
beat-IIa	beaten path IIa	0.011
CG13065	CG13065 gene product from transcript CG13065-RA	0.011
vn	vein	0.011
CG12645	CG12645 gene product from transcript CG12645-RB	0.011
nAcRbeta-64B	nicotinic Acetylcholine Receptor beta 64B	0.011
GluClalpha	CG7535 gene product from transcript CG7535-RG	0.011
Gr28a	Gustatory receptor 28a	0.011
Tusp	CG5586 gene product from transcript CG5586-RE	0.011
Cyp313b1	CG9716 gene product from transcript CG9716-RA	0.011
CG11203	CG11203 gene product from transcript CG11203-RB	0.011
Myo28B1	CG6976 gene product from transcript CG6976-RB	0.011
Art9	Arginine methyltransferase 9	0.011
CG42594	CG42594 gene product from transcript CG42594-RB	0.011
CG15005	CG15005 gene product from transcript CG15005-RA	0.011
CG3009	CG3009 gene product from transcript CG3009-RA	0.011
if	inflated	0.011
CG14854	CG14854 gene product from transcript CG14854-RB	0.011
CdsA	CDP diglyceride synthetase	0.010
CG13045	CG13045 gene product from transcript CG13045-RA	0.010
CG8046	CG8046 gene product from transcript CG8046-RA	0.010
CG11160	CG11160 gene product from transcript CG11160-RB	0.010
nAcRalpha-34E	nicotinic Acetylcholine Receptor alpha 34E	0.010
CG17922	CG17922 gene product from transcript CG17922-RA	0.010
adat	CG16889 gene product from transcript CG16889-RA	0.010
TwdlK	TweedleK	0.010
CG18577	CG18577 gene product from transcript CG18577-RA	0.010
CG16710	CG16710 gene product from transcript CG16710-RB	0.010
CG14871	CG14871 gene product from transcript CG14871-RB	0.010
CheB98a	Chemosensory protein A 98a	0.010
beat-Vc	CG14390 gene product from transcript CG14390-RA	0.010
Ac76E	Adenylyl cyclase 76E	0.010	Mouse Rat
CG32809	CG32809 gene product from transcript CG32809-RD	0.010
CG15485	CG15485 gene product from transcript CG15485-RA	0.010
CG7510	CG7510 gene product from transcript CG7510-RA	0.010
Dh	Diuretic hormone	0.010
Rapgap1	CG34374 gene product from transcript CG34374-RD	0.010
Ir11a	Ionotropic receptor 11a	0.010
Calx	Na/Ca-exchange protein	0.010
sut2	sugar transporter 2	0.010
be	ben	0.010
niki	nimA-like kinase	0.010