IMP

Process View

Homo sapiens

32 genes annotated in human

regulation of stress fiber assembly

Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of stress fiber assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of stress fiber assembly" (in gray)

Name	Description	Probability	Func Analog Organism
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	1.000
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	1.000	Human
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.993
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.992
FN1	fibronectin 1	0.968
RHOA	ras homolog gene family, member A	0.965
BAIAP2	BAI1-associated protein 2	0.915
S100A8	S100 calcium binding protein A8	0.791	Human
S100A6	S100 calcium binding protein A6	0.783	Human
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.778
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.710	Fly
ZYX	zyxin	0.670
FLNA	filamin A, alpha	0.567
S100B	S100 calcium binding protein B	0.502	Human
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.491
S100A11	S100 calcium binding protein A11	0.437	Human
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.437	Human
S100A9	S100 calcium binding protein A9	0.431	Human
FBLN1	fibulin 1	0.430
S100A1	S100 calcium binding protein A1	0.401	Human
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.393
RHOC	ras homolog gene family, member C	0.377	Human
ANXA2	annexin A2	0.347
ARHGAP1	Rho GTPase activating protein 1	0.319	Fly
ACTB	actin, beta	0.315
CTGF	connective tissue growth factor	0.267
S100A4	S100 calcium binding protein A4	0.262	Human
FYN	FYN oncogene related to SRC, FGR, YES	0.254
LMNA	lamin A/C	0.245
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.238
HTT	huntingtin	0.238
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.230
LGALS1	lectin, galactoside-binding, soluble, 1	0.229
PXN	paxillin	0.218
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.202
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.186	Fly
ACTG1	actin, gamma 1	0.176
SH3KBP1	SH3-domain kinase binding protein 1	0.164
VAV1	vav 1 guanine nucleotide exchange factor	0.162
EZR	ezrin	0.158	Human
PFN1	profilin 1	0.151
MYO10	myosin X	0.139
PALLD	palladin, cytoskeletal associated protein	0.137
EPS8	epidermal growth factor receptor pathway substrate 8	0.132
NCF2	neutrophil cytosolic factor 2	0.122
EMP3	epithelial membrane protein 3	0.119
SH3RF3	SH3 domain containing ring finger 3	0.103
RHOG	ras homolog gene family, member G (rho G)	0.102	Human
HP	haptoglobin	0.101
PLEC	plectin	0.099
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.097
IQGAP1	IQ motif containing GTPase activating protein 1	0.096
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.092
MSN	moesin	0.091	Human
SFN	stratifin	0.087
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.085
ANXA5	annexin A5	0.082
MYH9	myosin, heavy chain 9, non-muscle	0.079
ENG	endoglin	0.077
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.075
SCHIP1	schwannomin interacting protein 1	0.075
NCKAP1	NCK-associated protein 1	0.075
APOC1	apolipoprotein C-I	0.073
RAP1A	RAP1A, member of RAS oncogene family	0.069
SORBS3	sorbin and SH3 domain containing 3	0.067
ACTN1	actinin, alpha 1	0.062
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.060
TMSB10	thymosin beta 10	0.060
ALB	albumin	0.057
CYR61	cysteine-rich, angiogenic inducer, 61	0.056	Human
TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.055
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.053	Fly
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.052
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.051
A2M	alpha-2-macroglobulin	0.049
CAPG	capping protein (actin filament), gelsolin-like	0.047
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.047
VASP	vasodilator-stimulated phosphoprotein	0.047	Human
APOC3	apolipoprotein C-III	0.046
CD44	CD44 molecule (Indian blood group)	0.045
FLNB	filamin B, beta	0.044
WASL	Wiskott-Aldrich syndrome-like	0.044
DLG5	discs, large homolog 5 (Drosophila)	0.044
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.042
LCAT	lecithin-cholesterol acyltransferase	0.041
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.041
WASF1	WAS protein family, member 1	0.040	Human
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.039
AREG	amphiregulin	0.039
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.039
AGTPBP1	ATP/GTP binding protein 1	0.039
FMNL1	formin-like 1	0.039
DIAPH1	diaphanous homolog 1 (Drosophila)	0.038
RPTOR	regulatory associated protein of MTOR, complex 1	0.038
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.038
AMOTL2	angiomotin like 2	0.036
CALD1	caldesmon 1	0.036
UNC119	unc-119 homolog (C. elegans)	0.035
BCAR1	breast cancer anti-estrogen resistance 1	0.035
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.035
NCL	nucleolin	0.033
TSG101	tumor susceptibility gene 101	0.033
TIMP1	TIMP metallopeptidase inhibitor 1	0.033
VCL	vinculin	0.033
CYTH1	cytohesin 1	0.033
ITSN1	intersectin 1 (SH3 domain protein)	0.032
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.032
ANXA1	annexin A1	0.032
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.031
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.031
PTRF	polymerase I and transcript release factor	0.031
CNN2	calponin 2	0.030
INPPL1	inositol polyphosphate phosphatase-like 1	0.030
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.029	Fly
CLTC	clathrin, heavy chain (Hc)	0.029
SH3GL3	SH3-domain GRB2-like 3	0.029
SH3RF1	SH3 domain containing ring finger 1	0.029
TBC1D10A	TBC1 domain family, member 10A	0.029
SPRY2	sprouty homolog 2 (Drosophila)	0.028
RTKN	rhotekin	0.028
STK10	serine/threonine kinase 10	0.028
SORBS2	sorbin and SH3 domain containing 2	0.028	Human
HCK	hemopoietic cell kinase	0.028
CFL1	cofilin 1 (non-muscle)	0.028
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.027
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.027
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.027
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.027
ILK	integrin-linked kinase	0.027
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.027
COL17A1	collagen, type XVII, alpha 1	0.026
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.026
NCKIPSD	NCK interacting protein with SH3 domain	0.026
AGER	advanced glycosylation end product-specific receptor	0.026
COTL1	coactosin-like 1 (Dictyostelium)	0.026
ITGA6	integrin, alpha 6	0.026
VIM	vimentin	0.026
S100P	S100 calcium binding protein P	0.025	Human
CHN2	chimerin (chimaerin) 2	0.025
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.025
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.025
FGF18	fibroblast growth factor 18	0.024
UBC	ubiquitin C	0.024
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.024
JUP	junction plakoglobin	0.024
SYNJ2	synaptojanin 2	0.024
GAS7	growth arrest-specific 7	0.024
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.024
KSR1	kinase suppressor of ras 1	0.024
CAMSAP1L1	calmodulin regulated spectrin-associated protein 1-like 1	0.024
ITGB5	integrin, beta 5	0.023	Fly
AHNAK	AHNAK nucleoprotein	0.023
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.023
RDX	radixin	0.023	Human
TGFBR1	transforming growth factor, beta receptor 1	0.022
LGALS3	lectin, galactoside-binding, soluble, 3	0.022
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.022
DNM2	dynamin 2	0.021
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.021
EMP1	epithelial membrane protein 1	0.021
MYO9B	myosin IXB	0.021
WASF2	WAS protein family, member 2	0.021
ADAM9	ADAM metallopeptidase domain 9	0.021
GOLGB1	golgin B1	0.021
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.021
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.021
RPL11	ribosomal protein L11	0.021
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.020
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.020
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.020
S100A10	S100 calcium binding protein A10	0.020
TSC22D1	TSC22 domain family, member 1	0.020
FERMT2	fermitin family member 2	0.019
GRB2	growth factor receptor-bound protein 2	0.019
HIP1	huntingtin interacting protein 1	0.019
KLF2	Kruppel-like factor 2 (lung)	0.019
SH3BP2	SH3-domain binding protein 2	0.018
VCAM1	vascular cell adhesion molecule 1	0.018
CD2	CD2 molecule	0.018
APOE	apolipoprotein E	0.018	Human
QKI	quaking homolog, KH domain RNA binding (mouse)	0.018
ANGPTL4	angiopoietin-like 4	0.018
RRAS	related RAS viral (r-ras) oncogene homolog	0.018
ABI2	abl-interactor 2	0.018
APOA2	apolipoprotein A-II	0.017
PDCD6IP	programmed cell death 6 interacting protein	0.017
NCK1	NCK adaptor protein 1	0.017
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.017
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.017
LCK	lymphocyte-specific protein tyrosine kinase	0.017
GLTPD1	glycolipid transfer protein domain containing 1	0.017
TLN1	talin 1	0.017
NDUFB8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	0.016
S100A12	S100 calcium binding protein A12	0.016	Human
SMAD2	SMAD family member 2	0.016
LAD1	ladinin 1	0.016
PDLIM5	PDZ and LIM domain 5	0.016
PPAP2B	phosphatidic acid phosphatase type 2B	0.016
PRKCE	protein kinase C, epsilon	0.016
CLDN4	claudin 4	0.016
RAB6A	RAB6A, member RAS oncogene family	0.016
MPRIP	myosin phosphatase Rho interacting protein	0.016
ENAH	enabled homolog (Drosophila)	0.016	Human
FXYD5	FXYD domain containing ion transport regulator 5	0.016
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.015
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.015	Human
DEF6	differentially expressed in FDCP 6 homolog (mouse)	0.015
FEM1B	fem-1 homolog b (C. elegans)	0.015
PTPRC	protein tyrosine phosphatase, receptor type, C	0.015
ARHGAP29	Rho GTPase activating protein 29	0.015
DOCK2	dedicator of cytokinesis 2	0.015
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.015
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.015
NFIB	nuclear factor I/B	0.015
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.015
ERC2	ELKS/RAB6-interacting/CAST family member 2	0.015
PI3	peptidase inhibitor 3, skin-derived	0.014
SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	0.014
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.014
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.014
TLN2	talin 2	0.014
PTK2	PTK2 protein tyrosine kinase 2	0.014
ACVRL1	activin A receptor type II-like 1	0.014
CREBBP	CREB binding protein	0.014
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.014
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.014
ADAM15	ADAM metallopeptidase domain 15	0.014
RNF5	ring finger protein 5	0.014
FGA	fibrinogen alpha chain	0.014
XIRP1	xin actin-binding repeat containing 1	0.014
CLDN7	claudin 7	0.014
ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	0.014
INSR	insulin receptor	0.014
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.014
ARRB2	arrestin, beta 2	0.013
PAK4	p21 protein (Cdc42/Rac)-activated kinase 4	0.013
TPM4	tropomyosin 4	0.013
FYB	FYN binding protein	0.013
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.013
CTTN	cortactin	0.013
SPTBN1	spectrin, beta, non-erythrocytic 1	0.013
WIPF1	WAS/WASL interacting protein family, member 1	0.013
LASP1	LIM and SH3 protein 1	0.013
CFD	complement factor D (adipsin)	0.013
MED31	mediator complex subunit 31	0.013
TES	testis derived transcript (3 LIM domains)	0.013
WIF1	WNT inhibitory factor 1	0.013
CEP70	centrosomal protein 70kDa	0.013
SPRR2A	small proline-rich protein 2A	0.012
CSTA	cystatin A (stefin A)	0.012
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.012
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.012
GOLGA1	golgin A1	0.012
OSBPL3	oxysterol binding protein-like 3	0.012
DOCK1	dedicator of cytokinesis 1	0.012
DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.012
ING4	inhibitor of growth family, member 4	0.012
HOXB7	homeobox B7	0.012
KRT14	keratin 14	0.012
S100A2	S100 calcium binding protein A2	0.012	Human
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.012
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.012
PKP3	plakophilin 3	0.012
LRRK2	leucine-rich repeat kinase 2	0.012
APOC2	apolipoprotein C-II	0.012
PDIA3	protein disulfide isomerase family A, member 3	0.012
RAMP3	receptor (G protein-coupled) activity modifying protein 3	0.012
SFRP1	secreted frizzled-related protein 1	0.012
IGF1R	insulin-like growth factor 1 receptor	0.011
IRS2	insulin receptor substrate 2	0.011
GDF10	growth differentiation factor 10	0.011
PECAM1	platelet/endothelial cell adhesion molecule	0.011
LST1	leukocyte specific transcript 1	0.011
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.011
PLTP	phospholipid transfer protein	0.011
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	0.011
GORAB	golgin, RAB6-interacting	0.011
CRMP1	collapsin response mediator protein 1	0.011
CGN	cingulin	0.011
SH3BP4	SH3-domain binding protein 4	0.011
TRIM29	tripartite motif containing 29	0.011
GNL3L	guanine nucleotide binding protein-like 3 (nucleolar)-like	0.011
ACVR1	activin A receptor, type I	0.011
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	0.011
ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)	0.011
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.011	Fly
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.011
LYZ	lysozyme	0.011
RYBP	RING1 and YY1 binding protein	0.011
ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.011
CCDC113	coiled-coil domain containing 113	0.011
THBS1	thrombospondin 1	0.011
ALOX5AP	arachidonate 5-lipoxygenase-activating protein	0.011
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.011
LAMC2	laminin, gamma 2	0.011
KIAA1949	KIAA1949	0.011
ATP8	ATP synthase F0 subunit 8	0.011
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.011
ARHGAP15	Rho GTPase activating protein 15	0.011
PICALM	phosphatidylinositol binding clathrin assembly protein	0.011
HDAC7	histone deacetylase 7	0.011
PTEN	phosphatase and tensin homolog	0.010
SEPT7	septin 7	0.010
SYNJ1	synaptojanin 1	0.010
NCF4	neutrophil cytosolic factor 4, 40kDa	0.010
LCP1	lymphocyte cytosolic protein 1 (L-plastin)	0.010
NPNT	nephronectin	0.010
ARHGAP31	Rho GTPase activating protein 31	0.010
ADRB2	adrenergic, beta-2-, receptor, surface	0.010
ACAN	aggrecan	0.010
ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	0.010	Human
USP2	ubiquitin specific peptidase 2	0.010
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.010
SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.010
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.010
CCDC88A	coiled-coil domain containing 88A	0.010
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.010
PIM1	pim-1 oncogene	0.010
EFHD2	EF-hand domain family, member D2	0.010
SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	0.010