IMP

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Homo sapiens

18 genes annotated in human

Multi-species View

microtubule polymerization

GO:0046785

The addition of tubulin heterodimers to one or both ends of a microtubule.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "microtubule polymerization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "microtubule polymerization" (in gray)

Name	Description	Probability	Func Analog Organism
TUBGCP3	tubulin, gamma complex associated protein 3	0.994	Fly
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.963
MAPT	microtubule-associated protein tau	0.948
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.939
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.791
ANAPC4	anaphase promoting complex subunit 4	0.737
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.637
ANAPC7	anaphase promoting complex subunit 7	0.631
APC	adenomatous polyposis coli	0.591	Mouse
TBCD	tubulin folding cofactor D	0.571
ANAPC1	anaphase promoting complex subunit 1	0.558
KIF1B	kinesin family member 1B	0.535
ZNF746	zinc finger protein 746	0.495
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.475
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.425
TUBB	tubulin, beta	0.422
ANAPC5	anaphase promoting complex subunit 5	0.398
AURKA	aurora kinase A	0.393
TEX11	testis expressed 11	0.367
NEK6	NIMA (never in mitosis gene a)-related kinase 6	0.361
TUBA1C	tubulin, alpha 1c	0.349
MZT2B	mitotic spindle organizing protein 2B	0.306
MAPRE2	microtubule-associated protein, RP/EB family, member 2	0.303	Human
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.279
SPRR2A	small proline-rich protein 2A	0.277
FNBP1	formin binding protein 1	0.272
ARL2	ADP-ribosylation factor-like 2	0.259
MZT1	mitotic spindle organizing protein 1	0.254
KIF5B	kinesin family member 5B	0.251	Fly
ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	0.251
CCDC85A	coiled-coil domain containing 85A	0.242
CACYBP	calcyclin binding protein	0.231
TACC3	transforming, acidic coiled-coil containing protein 3	0.231
TUBB2C	tubulin, beta 2C	0.228
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.227
TUBA1B	tubulin, alpha 1b	0.223
TUBG1	tubulin, gamma 1	0.223	Worm
MAPRE3	microtubule-associated protein, RP/EB family, member 3	0.218	Human
FYN	FYN oncogene related to SRC, FGR, YES	0.214
TERF1	telomeric repeat binding factor (NIMA-interacting) 1	0.203
STIP1	stress-induced-phosphoprotein 1	0.190
TUBA4A	tubulin, alpha 4a	0.187
LMO2	LIM domain only 2 (rhombotin-like 1)	0.161
TERF2IP	telomeric repeat binding factor 2, interacting protein	0.159
CDK2	cyclin-dependent kinase 2	0.131
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.128
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.125
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.125
STIL	SCL/TAL1 interrupting locus	0.125
CEP135	centrosomal protein 135kDa	0.124
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.123
CDK11B	cyclin-dependent kinase 11B	0.108
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.099
SASS6	spindle assembly 6 homolog (C. elegans)	0.098
IMMT	inner membrane protein, mitochondrial	0.092
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	0.092
KIF23	kinesin family member 23	0.091
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.083
GTSE1	G-2 and S-phase expressed 1	0.082
KIF14	kinesin family member 14	0.081
ANAPC11	anaphase promoting complex subunit 11	0.080
PPID	peptidylprolyl isomerase D	0.077
PTTG1	pituitary tumor-transforming 1	0.073
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.070
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.066
PLK4	polo-like kinase 4	0.066
KIF20A	kinesin family member 20A	0.065
TOP3A	topoisomerase (DNA) III alpha	0.065
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.064
CENPF	centromere protein F, 350/400kDa (mitosin)	0.063
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.062
ORC4	origin recognition complex, subunit 4	0.060
MKI67	antigen identified by monoclonal antibody Ki-67	0.058
CENPE	centromere protein E, 312kDa	0.054
CDC23	cell division cycle 23 homolog (S. cerevisiae)	0.054
RIN3	Ras and Rab interactor 3	0.054
VPS29	vacuolar protein sorting 29 homolog (S. cerevisiae)	0.052
BLM	Bloom syndrome, RecQ helicase-like	0.052
APLP1	amyloid beta (A4) precursor-like protein 1	0.051
SEPT2	septin 2	0.051
KIF2C	kinesin family member 2C	0.048	Worm
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.047
NCAPG	non-SMC condensin I complex, subunit G	0.047
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.045
TUBGCP5	tubulin, gamma complex associated protein 5	0.044
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.044
CKAP5	cytoskeleton associated protein 5	0.044	Worm Fly
UNC119	unc-119 homolog (C. elegans)	0.044
SNCAIP	synuclein, alpha interacting protein	0.042
HJURP	Holliday junction recognition protein	0.039
FEN1	flap structure-specific endonuclease 1	0.038
CLIP1	CAP-GLY domain containing linker protein 1	0.035
S100A2	S100 calcium binding protein A2	0.035
BICD1	bicaudal D homolog 1 (Drosophila)	0.035
MTUS2	microtubule associated tumor suppressor candidate 2	0.034
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.034
TTK	TTK protein kinase	0.032
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.031
TPPP	tubulin polymerization promoting protein	0.030
CCNB1	cyclin B1	0.030
FBXW11	F-box and WD repeat domain containing 11	0.029
UBE2C	ubiquitin-conjugating enzyme E2C	0.028
ARIH2	ariadne homolog 2 (Drosophila)	0.027
SMAD9	SMAD family member 9	0.027
ANKRD17	ankyrin repeat domain 17	0.027
LUC7L2	LUC7-like 2 (S. cerevisiae)	0.026
CDC26	cell division cycle 26 homolog (S. cerevisiae)	0.026
ARL3	ADP-ribosylation factor-like 3	0.025
CEP55	centrosomal protein 55kDa	0.025
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.025
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.024
CTPS	CTP synthase	0.024
PDE4DIP	phosphodiesterase 4D interacting protein	0.024
PRC1	protein regulator of cytokinesis 1	0.024
ZNF775	zinc finger protein 775	0.023
EZR	ezrin	0.023
TUBB3	tubulin, beta 3	0.023
ERCC6L	excision repair cross-complementing rodent repair deficiency, complementation group 6-like	0.023
EVI5	ecotropic viral integration site 5	0.022
NUP133	nucleoporin 133kDa	0.022
HTT	huntingtin	0.022
FYB	FYN binding protein	0.021
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.021
TACC1	transforming, acidic coiled-coil containing protein 1	0.021
UBE2S	ubiquitin-conjugating enzyme E2S	0.020
DCTN1	dynactin 1	0.019
YAP1	Yes-associated protein 1	0.019
BTRC	beta-transducin repeat containing	0.019
GRAP2	GRB2-related adaptor protein 2	0.018
KCNE3	potassium voltage-gated channel, Isk-related family, member 3	0.018
PDPK1	3-phosphoinositide dependent protein kinase-1	0.018
CDCA3	cell division cycle associated 3	0.018
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.018
GSK3B	glycogen synthase kinase 3 beta	0.017
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.017
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.017
DNM1L	dynamin 1-like	0.017
CIT	citron (rho-interacting, serine/threonine kinase 21)	0.016
SPTBN1	spectrin, beta, non-erythrocytic 1	0.016
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.016
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.016
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.016
XPO1	exportin 1 (CRM1 homolog, yeast)	0.015
GIGYF2	GRB10 interacting GYF protein 2	0.015
FHL1	four and a half LIM domains 1	0.015
AARS	alanyl-tRNA synthetase	0.015
ACD	adrenocortical dysplasia homolog (mouse)	0.014
SAE1	SUMO1 activating enzyme subunit 1	0.014
CKS2	CDC28 protein kinase regulatory subunit 2	0.014
WRN	Werner syndrome, RecQ helicase-like	0.013
PSRC1	proline/serine-rich coiled-coil 1	0.013
HARS	histidyl-tRNA synthetase	0.013
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.013
HDAC4	histone deacetylase 4	0.013
SPAG5	sperm associated antigen 5	0.013
MFAP1	microfibrillar-associated protein 1	0.013
MCM10	minichromosome maintenance complex component 10	0.013
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	0.012
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.012
CCNF	cyclin F	0.012
KLC2	kinesin light chain 2	0.012
BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	0.012
CDYL	chromodomain protein, Y-like	0.012
RAI14	retinoic acid induced 14	0.011
KIAA1279	KIAA1279	0.011
HMMR	hyaluronan-mediated motility receptor (RHAMM)	0.011
GPRASP2	G protein-coupled receptor associated sorting protein 2	0.011
INTS7	integrator complex subunit 7	0.011
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.011
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.011
GPSM2	G-protein signaling modulator 2	0.011
VRK2	vaccinia related kinase 2	0.011
NEK9	NIMA (never in mitosis gene a)- related kinase 9	0.011
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.011
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	0.011
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.011
MARK1	MAP/microtubule affinity-regulating kinase 1	0.011
RNGTT	RNA guanylyltransferase and 5'-phosphatase	0.011
SKA1	spindle and kinetochore associated complex subunit 1	0.011
CCDC99	coiled-coil domain containing 99	0.011
MED21	mediator complex subunit 21	0.011
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.010
CDK8	cyclin-dependent kinase 8	0.010
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.010