IMP
Process View
positive regulation of tumor necrosis factor production
Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of tumor necrosis factor production"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TRAF2 | TNF receptor-associated factor 2 | 0.989 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.946 | ||
| MYD88 | myeloid differentiation primary response gene (88) | 0.932 | Mouse | |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.862 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.792 | Human Mouse | |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.762 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.738 | ||
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.620 | Human | |
| SYK | spleen tyrosine kinase | 0.610 | ||
| TLR2 | toll-like receptor 2 | 0.408 | ||
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.403 | Human | |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) | 0.398 | Human | |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.320 | ||
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.288 | ||
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.287 | ||
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.280 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.255 | ||
| NLRC4 | NLR family, CARD domain containing 4 | 0.247 | ||
| IDE | insulin-degrading enzyme | 0.227 | ||
| TRAF5 | TNF receptor-associated factor 5 | 0.213 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.192 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.192 | ||
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.183 | ||
| TLR4 | toll-like receptor 4 | 0.181 | ||
| TICAM2 | toll-like receptor adaptor molecule 2 | 0.179 | ||
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.177 | ||
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.175 | ||
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.173 | Human | |
| IL8 | interleukin 8 | 0.169 | ||
| CCL5 | chemokine (C-C motif) ligand 5 | 0.167 | ||
| IL23A | interleukin 23, alpha subunit p19 | 0.156 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.145 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.138 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.129 | Rat | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.127 | Human | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.103 | ||
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.102 | Human | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.083 | Rat | |
| MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 0.074 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.071 | ||
| IL1B | interleukin 1, beta | 0.069 | ||
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.063 | ||
| CCL8 | chemokine (C-C motif) ligand 8 | 0.063 | ||
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.056 | ||
| CCR1 | chemokine (C-C motif) receptor 1 | 0.050 | ||
| PLEK | pleckstrin | 0.049 | ||
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.049 | ||
| CD48 | CD48 molecule | 0.048 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.043 | ||
| CCL2 | chemokine (C-C motif) ligand 2 | 0.039 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.036 | ||
| CYBB | cytochrome b-245, beta polypeptide | 0.036 | ||
| PYDC2 | pyrin domain containing 2 | 0.035 | ||
| DPP4 | dipeptidyl-peptidase 4 | 0.033 | ||
| UBD | ubiquitin D | 0.033 | ||
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.032 | ||
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.032 | ||
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.031 | Human | |
| IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.031 | ||
| TRAF3 | TNF receptor-associated factor 3 | 0.030 | ||
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.029 | ||
| TMEM173 | transmembrane protein 173 | 0.028 | ||
| CD86 | CD86 molecule | 0.028 | ||
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.027 | ||
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) | 0.027 | ||
| BLNK | B-cell linker | 0.026 | ||
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.026 | Human | |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.025 | ||
| MPO | myeloperoxidase | 0.025 | ||
| CCL13 | chemokine (C-C motif) ligand 13 | 0.025 | ||
| CD33 | CD33 molecule | 0.025 | ||
| IL6 | interleukin 6 (interferon, beta 2) | 0.024 | ||
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.023 | ||
| CYTIP | cytohesin 1 interacting protein | 0.021 | ||
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.021 | ||
| ESR1 | estrogen receptor 1 | 0.020 | ||
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.020 | ||
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.019 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.019 | ||
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.019 | ||
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.019 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.019 | ||
| CRYAB | crystallin, alpha B | 0.019 | ||
| S100A12 | S100 calcium binding protein A12 | 0.019 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.019 | ||
| LY86 | lymphocyte antigen 86 | 0.018 | ||
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.018 | ||
| TFEC | transcription factor EC | 0.018 | ||
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.017 | Mouse | |
| GATA2 | GATA binding protein 2 | 0.017 | ||
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.016 | ||
| CSF1R | colony stimulating factor 1 receptor | 0.016 | ||
| CCR2 | chemokine (C-C motif) receptor 2 | 0.016 | Mouse Rat | |
| IRF1 | interferon regulatory factor 1 | 0.016 | ||
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.016 | ||
| AIM2 | absent in melanoma 2 | 0.015 | ||
| S100A8 | S100 calcium binding protein A8 | 0.015 | ||
| CD28 | CD28 molecule | 0.015 | ||
| CCL3 | chemokine (C-C motif) ligand 3 | 0.015 | Mouse | |
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.015 | ||
| TNF | tumor necrosis factor | 0.015 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.015 | ||
| MTA3 | metastasis associated 1 family, member 3 | 0.015 | ||
| LTF | lactotransferrin | 0.015 | ||
| IFNGR1 | interferon gamma receptor 1 | 0.015 | ||
| EMR1 | egf-like module containing, mucin-like, hormone receptor-like 1 | 0.015 | ||
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.015 | Human | |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.014 | ||
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.014 | ||
| IL15 | interleukin 15 | 0.014 | ||
| IL10 | interleukin 10 | 0.014 | ||
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.014 | Human | |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 0.014 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.014 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.014 | Mouse | |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.013 | ||
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.013 | ||
| IFNG | interferon, gamma | 0.013 | ||
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.013 | ||
| CREBBP | CREB binding protein | 0.013 | ||
| AIF1 | allograft inflammatory factor 1 | 0.013 | ||
| FADD | Fas (TNFRSF6)-associated via death domain | 0.013 | ||
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.012 | ||
| RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.012 | Human | |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.012 | ||
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.012 | ||
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.012 | ||
| CD163 | CD163 molecule | 0.012 | ||
| MTA1 | metastasis associated 1 | 0.012 | ||
| IFIH1 | interferon induced with helicase C domain 1 | 0.012 | ||
| SELE | selectin E | 0.012 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.012 | ||
| SAMHD1 | SAM domain and HD domain 1 | 0.012 | ||
| VCAM1 | vascular cell adhesion molecule 1 | 0.012 | ||
| FPR3 | formyl peptide receptor 3 | 0.012 | ||
| IL12A | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 0.012 | ||
| DEFA4 | defensin, alpha 4, corticostatin | 0.012 | ||
| BST1 | bone marrow stromal cell antigen 1 | 0.011 | ||
| CLEC4A | C-type lectin domain family 4, member A | 0.011 | ||
| CD53 | CD53 molecule | 0.011 | ||
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.011 | ||
| MTA2 | metastasis associated 1 family, member 2 | 0.011 | ||
| IGSF6 | immunoglobulin superfamily, member 6 | 0.011 | ||
| SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.011 | ||
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.010 | ||
| CMIP | c-Maf-inducing protein | 0.010 | ||
| STAT5A | signal transducer and activator of transcription 5A | 0.010 | ||
| TLR7 | toll-like receptor 7 | 0.010 | ||
| LAMP3 | lysosomal-associated membrane protein 3 | 0.010 | ||
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.010 |