IMP

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Homo sapiens

21 genes annotated in human

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cytoskeleton dependent intracellular transport

GO:0030705

The directed movement of substances along cytoskeletal elements such as microfilaments or microtubules within a cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cytoskeleton dependent intracellular transport"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cytoskeleton dependent intracellular transport" (in gray)

Name	Description	Probability	Func Analog Organism
GSK3B	glycogen synthase kinase 3 beta	0.598
DTNA	dystrobrevin, alpha	0.571
APC	adenomatous polyposis coli	0.567
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.479	Mouse Fly
DYNLT3	dynein, light chain, Tctex-type 3	0.463
MAPK1	mitogen-activated protein kinase 1	0.404
NCAM1	neural cell adhesion molecule 1	0.384
GBA	glucosidase, beta, acid	0.354
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.345
CLASP1	cytoplasmic linker associated protein 1	0.342
DCTN1	dynactin 1	0.255
VHL	von Hippel-Lindau tumor suppressor	0.243
LRRK2	leucine-rich repeat kinase 2	0.220
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.189	Mouse
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.173
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.153
EGLN1	egl nine homolog 1 (C. elegans)	0.152
KIF5B	kinesin family member 5B	0.149	Mouse Rat Fly
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.146
OPTN	optineurin	0.135
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.131
TRIM63	tripartite motif containing 63	0.119
TSC2	tuberous sclerosis 2	0.117
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.114
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.106
UNC119	unc-119 homolog (C. elegans)	0.095
MAP4	microtubule-associated protein 4	0.094
MAP2K7	mitogen-activated protein kinase kinase 7	0.092
APP	amyloid beta (A4) precursor protein	0.089	Mouse
OSBPL9	oxysterol binding protein-like 9	0.088
CLIP1	CAP-GLY domain containing linker protein 1	0.088
GOLGA2	golgin A2	0.087
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.084
RUSC2	RUN and SH3 domain containing 2	0.080
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.077
NCSTN	nicastrin	0.077
BBS4	Bardet-Biedl syndrome 4	0.076
DYNLL1	dynein, light chain, LC8-type 1	0.074
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	0.074
AGTPBP1	ATP/GTP binding protein 1	0.070
PEX13	peroxisomal biogenesis factor 13	0.070
MAPT	microtubule-associated protein tau	0.067	Mouse
SEPT2	septin 2	0.066
ARNT	aryl hydrocarbon receptor nuclear translocator	0.055
KIFAP3	kinesin-associated protein 3	0.053
MAPK14	mitogen-activated protein kinase 14	0.052
WDR48	WD repeat domain 48	0.051
DUSP3	dual specificity phosphatase 3	0.050
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.048
CRMP1	collapsin response mediator protein 1	0.048
SDCBP	syndecan binding protein (syntenin)	0.048
VAMP7	vesicle-associated membrane protein 7	0.047
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.047
RAI14	retinoic acid induced 14	0.046
SMAD9	SMAD family member 9	0.044
KIAA0368	KIAA0368	0.044
RAB2A	RAB2A, member RAS oncogene family	0.044
KIAA0408	KIAA0408	0.043
PIAS4	protein inhibitor of activated STAT, 4	0.043
MAPK8	mitogen-activated protein kinase 8	0.042
TUBA1A	tubulin, alpha 1a	0.040
EXOC1	exocyst complex component 1	0.039
STK3	serine/threonine kinase 3	0.038
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.038
DMXL1	Dmx-like 1	0.038
CSNK1G2	casein kinase 1, gamma 2	0.036
DMD	dystrophin	0.035
ARL2	ADP-ribosylation factor-like 2	0.034
PTPRR	protein tyrosine phosphatase, receptor type, R	0.033
SQSTM1	sequestosome 1	0.033
FAM82A2	family with sequence similarity 82, member A2	0.032
DYNC2LI1	dynein, cytoplasmic 2, light intermediate chain 1	0.030
NEK1	NIMA (never in mitosis gene a)-related kinase 1	0.029
CHD3	chromodomain helicase DNA binding protein 3	0.029
PEX5	peroxisomal biogenesis factor 5	0.029
EPS8	epidermal growth factor receptor pathway substrate 8	0.029
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.029
YAP1	Yes-associated protein 1	0.028
NCAPG	non-SMC condensin I complex, subunit G	0.028
ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	0.027
POLI	polymerase (DNA directed) iota	0.027
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.027
KLC1	kinesin light chain 1	0.026	Mouse
MBIP	MAP3K12 binding inhibitory protein 1	0.026
WDYHV1	WDYHV motif containing 1	0.026
EGLN3	egl nine homolog 3 (C. elegans)	0.025
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.025
RABAC1	Rab acceptor 1 (prenylated)	0.025
IFT88	intraflagellar transport 88 homolog (Chlamydomonas)	0.025
SFN	stratifin	0.025
BBS2	Bardet-Biedl syndrome 2	0.025
KLC2	kinesin light chain 2	0.025	Mouse
NIN	ninein (GSK3B interacting protein)	0.024
ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	0.024
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.024
ITSN1	intersectin 1 (SH3 domain protein)	0.024
ARF5	ADP-ribosylation factor 5	0.023
RNF20	ring finger protein 20	0.023
RAB6A	RAB6A, member RAS oncogene family	0.023
GTSE1	G-2 and S-phase expressed 1	0.023
TJP2	tight junction protein 2 (zona occludens 2)	0.023
WDFY3	WD repeat and FYVE domain containing 3	0.023
CCDC53	coiled-coil domain containing 53	0.023
PRKCZ	protein kinase C, zeta	0.023	Rat
AGGF1	angiogenic factor with G patch and FHA domains 1	0.022
RAP1GAP	RAP1 GTPase activating protein	0.022
OR5AR1	olfactory receptor, family 5, subfamily AR, member 1	0.022
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.022
MAP2K4	mitogen-activated protein kinase kinase 4	0.021
PEX19	peroxisomal biogenesis factor 19	0.021
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.021
POU2F1	POU class 2 homeobox 1	0.020
HTT	huntingtin	0.019
CEP70	centrosomal protein 70kDa	0.019
CHMP1A	chromatin modifying protein 1A	0.019
PEA15	phosphoprotein enriched in astrocytes 15	0.019
GNS	glucosamine (N-acetyl)-6-sulfatase	0.019
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.019
MARK2	MAP/microtubule affinity-regulating kinase 2	0.019
PDCD6IP	programmed cell death 6 interacting protein	0.019
MPRIP	myosin phosphatase Rho interacting protein	0.018
USP8	ubiquitin specific peptidase 8	0.018
TXN	thioredoxin	0.018
SH3KBP1	SH3-domain kinase binding protein 1	0.018
DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	0.018	Rat Fly
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.018
LMO4	LIM domain only 4	0.017
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.017
VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C	0.017	Fly
KLC4	kinesin light chain 4	0.017
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.017
ARL15	ADP-ribosylation factor-like 15	0.017
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.017
BACE1	beta-site APP-cleaving enzyme 1	0.017
ATP6V1E1	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	0.017
ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.017
CAPNS1	calpain, small subunit 1	0.017
HDAC7	histone deacetylase 7	0.017
APLP1	amyloid beta (A4) precursor-like protein 1	0.017
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.016
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.016
ACTL6B	actin-like 6B	0.016
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.016
PCM1	pericentriolar material 1	0.016
RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	0.016
SLAIN2	SLAIN motif family, member 2	0.016
SSX2IP	synovial sarcoma, X breakpoint 2 interacting protein	0.016
PEX12	peroxisomal biogenesis factor 12	0.016
ADAM9	ADAM metallopeptidase domain 9	0.016
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.016
RECQL5	RecQ protein-like 5	0.016
WSB2	WD repeat and SOCS box containing 2	0.016
ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1	0.016
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.016
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.016
SAV1	salvador homolog 1 (Drosophila)	0.015
RAB10	RAB10, member RAS oncogene family	0.015
GPAA1	glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)	0.015
RALGPS2	Ral GEF with PH domain and SH3 binding motif 2	0.015
STK25	serine/threonine kinase 25	0.015
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.015
PITPNA	phosphatidylinositol transfer protein, alpha	0.015
BAIAP2	BAI1-associated protein 2	0.015
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.015
NMT2	N-myristoyltransferase 2	0.015
KIAA1009	KIAA1009	0.015
EFCAB7	EF-hand calcium binding domain 7	0.015
DOCK7	dedicator of cytokinesis 7	0.015
PI4KB	phosphatidylinositol 4-kinase, catalytic, beta	0.014
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.014	Fly
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.014
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.014
GDI1	GDP dissociation inhibitor 1	0.014
HDAC4	histone deacetylase 4	0.014
SNAP25	synaptosomal-associated protein, 25kDa	0.014
GGH	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)	0.014
RTN4	reticulon 4	0.014
RAB9A	RAB9A, member RAS oncogene family	0.014
RAB18	RAB18, member RAS oncogene family	0.014
TRMT1L	TRM1 tRNA methyltransferase 1-like	0.014
ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A	0.014
LARP1	La ribonucleoprotein domain family, member 1	0.013
PEX16	peroxisomal biogenesis factor 16	0.013
MFSD1	major facilitator superfamily domain containing 1	0.013
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.013
BICD1	bicaudal D homolog 1 (Drosophila)	0.013
NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.013
CENPF	centromere protein F, 350/400kDa (mitosin)	0.013
RNF13	ring finger protein 13	0.013
GOLGA7	golgin A7	0.013
GAP43	growth associated protein 43	0.013
FOXK1	forkhead box K1	0.013
RASSF3	Ras association (RalGDS/AF-6) domain family member 3	0.013
TDRD3	tudor domain containing 3	0.013
CDK10	cyclin-dependent kinase 10	0.013
CLTB	clathrin, light chain B	0.013
BHLHE40	basic helix-loop-helix family, member e40	0.012
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.012
OSBPL3	oxysterol binding protein-like 3	0.012
DTNBP1	dystrobrevin binding protein 1	0.012
MARK3	MAP/microtubule affinity-regulating kinase 3	0.012
CENPE	centromere protein E, 312kDa	0.012
MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	0.012
HSDL2	hydroxysteroid dehydrogenase like 2	0.012
DCTN2	dynactin 2 (p50)	0.012
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.012
HSPA1B	heat shock 70kDa protein 1B	0.012
ARFGAP2	ADP-ribosylation factor GTPase activating protein 2	0.012
HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor	0.012
CEP290	centrosomal protein 290kDa	0.012
SPATA7	spermatogenesis associated 7	0.012
BAD	BCL2-associated agonist of cell death	0.012
APOBEC3B	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B	0.012
HEXB	hexosaminidase B (beta polypeptide)	0.012
SMAD1	SMAD family member 1	0.012
CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.012
LAPTM4A	lysosomal protein transmembrane 4 alpha	0.012
FBXL5	F-box and leucine-rich repeat protein 5	0.012
ERBB2IP	erbb2 interacting protein	0.012
EFHC1	EF-hand domain (C-terminal) containing 1	0.012
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.012
SH3BGRL	SH3 domain binding glutamic acid-rich protein like	0.012
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.012
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.012
SNX3	sorting nexin 3	0.011
ARMCX3	armadillo repeat containing, X-linked 3	0.011
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.011
LRMP	lymphoid-restricted membrane protein	0.011
KIAA0930	KIAA0930	0.011
ZNF148	zinc finger protein 148	0.011
EDC3	enhancer of mRNA decapping 3 homolog (S. cerevisiae)	0.011
KIFC2	kinesin family member C2	0.011
KCNE3	potassium voltage-gated channel, Isk-related family, member 3	0.011
AR	androgen receptor	0.011
CCDC104	coiled-coil domain containing 104	0.011
DYNC1LI2	dynein, cytoplasmic 1, light intermediate chain 2	0.011
UNC45A	unc-45 homolog A (C. elegans)	0.011
TNFRSF21	tumor necrosis factor receptor superfamily, member 21	0.011
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.011
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.011
RASSF2	Ras association (RalGDS/AF-6) domain family member 2	0.011
CRYAB	crystallin, alpha B	0.011
GANAB	glucosidase, alpha; neutral AB	0.011
DAZAP2	DAZ associated protein 2	0.011
ATXN1	ataxin 1	0.011
CREBL2	cAMP responsive element binding protein-like 2	0.011
SH3BP4	SH3-domain binding protein 4	0.011
MARK1	MAP/microtubule affinity-regulating kinase 1	0.010
ATXN3	ataxin 3	0.010
MAPK3	mitogen-activated protein kinase 3	0.010
MYOZ1	myozenin 1	0.010
CPSF1	cleavage and polyadenylation specific factor 1, 160kDa	0.010
DCX	doublecortin	0.010
TIAM1	T-cell lymphoma invasion and metastasis 1	0.010
PLXNA3	plexin A3	0.010
KIAA1191	KIAA1191	0.010
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.010
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.010
CORO1B	coronin, actin binding protein, 1B	0.010
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.010	Fly
A2M	alpha-2-macroglobulin	0.010
PTPRS	protein tyrosine phosphatase, receptor type, S	0.010
DHRS4	dehydrogenase/reductase (SDR family) member 4	0.010
PRNP	prion protein	0.010
ING4	inhibitor of growth family, member 4	0.010
ITM2B	integral membrane protein 2B	0.010
TNNT1	troponin T type 1 (skeletal, slow)	0.010