IMP
Process View
protein sumoylation
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "protein sumoylation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 1.000 | ||
| SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 1.000 | ||
| SUMO2 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) | 0.984 | ||
| TP53 | tumor protein p53 | 0.963 | ||
| DAXX | death-domain associated protein | 0.937 | ||
| EGR1 | early growth response 1 | 0.884 | ||
| RANGAP1 | Ran GTPase activating protein 1 | 0.839 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.826 | ||
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.800 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.681 | ||
| MBD1 | methyl-CpG binding domain protein 1 | 0.667 | ||
| NAP1L5 | nucleosome assembly protein 1-like 5 | 0.635 | ||
| HDAC3 | histone deacetylase 3 | 0.600 | ||
| CTAG1B | cancer/testis antigen 1B | 0.470 | ||
| SMAD4 | SMAD family member 4 | 0.465 | ||
| NSMCE1 | non-SMC element 1 homolog (S. cerevisiae) | 0.372 | ||
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.355 | ||
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.333 | ||
| USPL1 | ubiquitin specific peptidase like 1 | 0.328 | ||
| SP100 | SP100 nuclear antigen | 0.307 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.291 | ||
| MEF2C | myocyte enhancer factor 2C | 0.291 | ||
| EID2 | EP300 interacting inhibitor of differentiation 2 | 0.253 | ||
| PML | promyelocytic leukemia | 0.229 | ||
| EGR3 | early growth response 3 | 0.229 | Human | |
| EGR2 | early growth response 2 | 0.223 | Human | |
| MAGEA2 | melanoma antigen family A, 2 | 0.215 | ||
| NSMCE4A | non-SMC element 4 homolog A (S. cerevisiae) | 0.204 | ||
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.204 | ||
| MAGEA3 | melanoma antigen family A, 3 | 0.181 | ||
| ELK1 | ELK1, member of ETS oncogene family | 0.159 | ||
| MAGEA6 | melanoma antigen family A, 6 | 0.158 | Human | |
| EID2B | EP300 interacting inhibitor of differentiation 2B | 0.136 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.129 | ||
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.119 | ||
| MAGEA12 | melanoma antigen family A, 12 | 0.106 | Human | |
| EID3 | EP300 interacting inhibitor of differentiation 3 | 0.104 | ||
| PRKD2 | protein kinase D2 | 0.097 | ||
| TRIM25 | tripartite motif containing 25 | 0.096 | ||
| HDAC4 | histone deacetylase 4 | 0.094 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.091 | ||
| TTN | titin | 0.082 | ||
| ZNF420 | zinc finger protein 420 | 0.080 | ||
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.078 | ||
| EID1 | EP300 interacting inhibitor of differentiation 1 | 0.075 | ||
| CBX5 | chromobox homolog 5 | 0.075 | ||
| SATB1 | SATB homeobox 1 | 0.073 | ||
| SUMO3 | SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) | 0.068 | ||
| TRIM63 | tripartite motif containing 63 | 0.067 | ||
| DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.066 | ||
| TRIM69 | tripartite motif containing 69 | 0.066 | ||
| MAGEA5 | melanoma antigen family A, 5 | 0.066 | ||
| BCL6 | B-cell CLL/lymphoma 6 | 0.065 | ||
| CAPNS1 | calpain, small subunit 1 | 0.064 | ||
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.058 | ||
| SENP1 | SUMO1/sentrin specific peptidase 1 | 0.057 | ||
| SFN | stratifin | 0.056 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.055 | ||
| PJA1 | praja ring finger 1 | 0.052 | ||
| SMAD2 | SMAD family member 2 | 0.052 | ||
| TRIM27 | tripartite motif containing 27 | 0.051 | ||
| EIF2C2 | eukaryotic translation initiation factor 2C, 2 | 0.048 | ||
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.047 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.047 | ||
| EIF2C1 | eukaryotic translation initiation factor 2C, 1 | 0.046 | ||
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.042 | ||
| SKIL | SKI-like oncogene | 0.041 | ||
| SMAD1 | SMAD family member 1 | 0.040 | ||
| MAGEA1 | melanoma antigen family A, 1 (directs expression of antigen MZ2-E) | 0.037 | Human | |
| MOAP1 | modulator of apoptosis 1 | 0.037 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.037 | ||
| HIPK1 | homeodomain interacting protein kinase 1 | 0.036 | ||
| RANBP2 | RAN binding protein 2 | 0.036 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.035 | ||
| SETDB1 | SET domain, bifurcated 1 | 0.033 | ||
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 0.033 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.032 | ||
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.032 | ||
| MEF2A | myocyte enhancer factor 2A | 0.031 | ||
| SP1 | Sp1 transcription factor | 0.030 | ||
| APC | adenomatous polyposis coli | 0.029 | ||
| GET4 | golgi to ER traffic protein 4 homolog (S. cerevisiae) | 0.029 | ||
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.028 | ||
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.027 | Human | |
| HERC5 | hect domain and RLD 5 | 0.027 | ||
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.026 | ||
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.026 | ||
| BTBD2 | BTB (POZ) domain containing 2 | 0.026 | ||
| TNRC6A | trinucleotide repeat containing 6A | 0.025 | ||
| IPO13 | importin 13 | 0.025 | ||
| SNIP1 | Smad nuclear interacting protein 1 | 0.024 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.024 | ||
| MYCN | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.024 | ||
| MYH10 | myosin, heavy chain 10, non-muscle | 0.023 | ||
| MAGEA4 | melanoma antigen family A, 4 | 0.023 | Human | |
| PHC1 | polyhomeotic homolog 1 (Drosophila) | 0.022 | ||
| SNAI1 | snail homolog 1 (Drosophila) | 0.022 | ||
| TRIM33 | tripartite motif containing 33 | 0.022 | Human | |
| FOXP3 | forkhead box P3 | 0.022 | ||
| IKZF3 | IKAROS family zinc finger 3 (Aiolos) | 0.021 | ||
| MYB | v-myb myeloblastosis viral oncogene homolog (avian) | 0.021 | ||
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.021 | ||
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.020 | ||
| CYLD | cylindromatosis (turban tumor syndrome) | 0.020 | ||
| SSX3 | synovial sarcoma, X breakpoint 3 | 0.020 | ||
| RBBP7 | retinoblastoma binding protein 7 | 0.020 | ||
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.020 | ||
| CASP8AP2 | caspase 8 associated protein 2 | 0.020 | ||
| MAGED1 | melanoma antigen family D, 1 | 0.019 | ||
| SAMD9 | sterile alpha motif domain containing 9 | 0.019 | ||
| IFI44 | interferon-induced protein 44 | 0.018 | ||
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.018 | ||
| TARBP2 | TAR (HIV-1) RNA binding protein 2 | 0.018 | ||
| RUFY1 | RUN and FYVE domain containing 1 | 0.018 | ||
| PPARA | peroxisome proliferator-activated receptor alpha | 0.018 | ||
| PARP1 | poly (ADP-ribose) polymerase 1 | 0.018 | ||
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.017 | ||
| MAGEC2 | melanoma antigen family C, 2 | 0.017 | Human | |
| RNF4 | ring finger protein 4 | 0.017 | ||
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.017 | ||
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) | 0.017 | ||
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 | 0.016 | ||
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.016 | ||
| TNIP1 | TNFAIP3 interacting protein 1 | 0.016 | ||
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.016 | ||
| PIWIL1 | piwi-like 1 (Drosophila) | 0.015 | ||
| MAGEB2 | melanoma antigen family B, 2 | 0.014 | Human | |
| MAGEA9B | melanoma antigen family A, 9B | 0.014 | Human | |
| PLK1 | polo-like kinase 1 | 0.014 | ||
| ACP5 | acid phosphatase 5, tartrate resistant | 0.014 | ||
| TDG | thymine-DNA glycosylase | 0.014 | ||
| MAGEC1 | melanoma antigen family C, 1 | 0.013 | Human | |
| MTA1 | metastasis associated 1 | 0.013 | ||
| CUL7 | cullin 7 | 0.013 | ||
| SAE1 | SUMO1 activating enzyme subunit 1 | 0.013 | ||
| USP42 | ubiquitin specific peptidase 42 | 0.013 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.012 | ||
| ZMYM2 | zinc finger, MYM-type 2 | 0.012 | ||
| MAGEA8 | melanoma antigen family A, 8 | 0.012 | Human | |
| TDRD7 | tudor domain containing 7 | 0.012 | ||
| DSP | desmoplakin | 0.012 | ||
| SAMD9L | sterile alpha motif domain containing 9-like | 0.012 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.012 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.012 | ||
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.012 | ||
| HSPB1 | heat shock 27kDa protein 1 | 0.012 | ||
| NCOA2 | nuclear receptor coactivator 2 | 0.012 | ||
| AICDA | activation-induced cytidine deaminase | 0.011 | ||
| SMC5 | structural maintenance of chromosomes 5 | 0.011 | ||
| HDAC5 | histone deacetylase 5 | 0.011 | Human | |
| RING1 | ring finger protein 1 | 0.011 | ||
| CBX8 | chromobox homolog 8 | 0.011 | ||
| CTAG2 | cancer/testis antigen 2 | 0.011 | ||
| DTX3L | deltex 3-like (Drosophila) | 0.011 | ||
| DUSP2 | dual specificity phosphatase 2 | 0.011 | ||
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.011 | ||
| USP18 | ubiquitin specific peptidase 18 | 0.011 | ||
| OPTN | optineurin | 0.011 | ||
| TRIM28 | tripartite motif containing 28 | 0.010 | ||
| NEB | nebulin | 0.010 | ||
| MAGEA11 | melanoma antigen family A, 11 | 0.010 | ||
| CREBBP | CREB binding protein | 0.010 |