IMP

Process View

Mus musculus

9 genes annotated in mouse

regulation of dna templated transcription in response to stress

Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of dna templated transcription in response to stress"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of dna templated transcription in response to stress" (in gray)

Name	Description	Probability	Func Analog Organism
Pten	phosphatase and tensin homolog	1.000
Nos3	nitric oxide synthase 3, endothelial cell	0.989
Vhl	von Hippel-Lindau tumor suppressor	0.988	Human
Trp53	transformation related protein 53	0.967	Fly
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.922
Rxra	retinoid X receptor alpha	0.913
Fos	FBJ osteosarcoma oncogene	0.913
Notch2	Notch gene homolog 2 (Drosophila)	0.872	Mouse
Lepr	leptin receptor	0.852
Bcl2	B-cell leukemia/lymphoma 2	0.847
Psen1	presenilin 1	0.788
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.773
Ahr	aryl-hydrocarbon receptor	0.744
Dusp1	dual specificity phosphatase 1	0.696
Egr1	early growth response 1	0.682
Ar	androgen receptor	0.656
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.632
Notch1	Notch gene homolog 1 (Drosophila)	0.628
Ctnnb1	catenin (cadherin associated protein), beta 1	0.599
Mapk8	mitogen-activated protein kinase 8	0.513	Yeast
Hif1a	hypoxia inducible factor 1, alpha subunit	0.504
Ptgs2	prostaglandin-endoperoxide synthase 2	0.500
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.473
Lama5	laminin, alpha 5	0.469
Fgfr2	fibroblast growth factor receptor 2	0.414
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.409
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.379
Arid1a	AT rich interactive domain 1A (SWI-like)	0.375
Kit	kit oncogene	0.336
Trib3	tribbles homolog 3 (Drosophila)	0.333
Vegfa	vascular endothelial growth factor A	0.331	Human
Jun	Jun oncogene	0.328	Human
Pparg	peroxisome proliferator activated receptor gamma	0.324
Rb1	retinoblastoma 1	0.324
Gdnf	glial cell line derived neurotrophic factor	0.289
Btg2	B-cell translocation gene 2, anti-proliferative	0.251
Mdm2	transformed mouse 3T3 cell double minute 2	0.251
Apc	adenomatosis polyposis coli	0.243
Egln1	EGL nine homolog 1 (C. elegans)	0.242
Mapk14	mitogen-activated protein kinase 14	0.230	Yeast
Apoe	apolipoprotein E	0.228
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.218
Hdac7	histone deacetylase 7	0.205
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.203
Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.201
Klf4	Kruppel-like factor 4 (gut)	0.193
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.188
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.186
Arid1b	AT rich interactive domain 1B (SWI-like)	0.186
Foxo1	forkhead box O1	0.182	Worm
Fgf8	fibroblast growth factor 8	0.171
Trp63	transformation related protein 63	0.164	Fly
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.157
Jarid2	jumonji, AT rich interactive domain 2	0.143
Col4a3	collagen, type IV, alpha 3	0.136
Brca1	breast cancer 1	0.135
Atf2	activating transcription factor 2	0.135
Ncoa3	nuclear receptor coactivator 3	0.134
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.128
Cd151	CD151 antigen	0.125
Smad3	MAD homolog 3 (Drosophila)	0.123
Jag1	jagged 1	0.118
Ghr	growth hormone receptor	0.116
Crebbp	CREB binding protein	0.115
Esr1	estrogen receptor 1 (alpha)	0.113
Skil	SKI-like	0.110
Stat3	signal transducer and activator of transcription 3	0.098
Efnb2	ephrin B2	0.098
Insr	insulin receptor	0.097
Pitx2	paired-like homeodomain transcription factor 2	0.097
Hdac4	histone deacetylase 4	0.095
Klf6	Kruppel-like factor 6	0.094
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.089
Egfr	epidermal growth factor receptor	0.086
Hr	hairless	0.083
Junb	Jun-B oncogene	0.083
Egr2	early growth response 2	0.082	Mouse
Egfl7	EGF-like domain 7	0.081
Atf3	activating transcription factor 3	0.079
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.078
Rhob	ras homolog gene family, member B	0.078
Irs2	insulin receptor substrate 2	0.078
Chd7	chromodomain helicase DNA binding protein 7	0.077
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.074
Sox2	SRY-box containing gene 2	0.073
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.072
Gata4	GATA binding protein 4	0.071
Nab2	Ngfi-A binding protein 2	0.068
Dll1	delta-like 1 (Drosophila)	0.067
Pkd1	polycystic kidney disease 1 homolog	0.066
Lep	leptin	0.065
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.064
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.061
Ep300	E1A binding protein p300	0.061
Sertad1	SERTA domain containing 1	0.060
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.060	Yeast
Cav1	caveolin 1, caveolae protein	0.058
Npc1	Niemann Pick type C1	0.055
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.053
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.053
Hdac5	histone deacetylase 5	0.052
Rbl2	retinoblastoma-like 2	0.049
Stag1	stromal antigen 1	0.049
Zfp36	zinc finger protein 36	0.048
Otp	orthopedia homolog (Drosophila)	0.045
Sqstm1	sequestosome 1	0.042
Dusp2	dual specificity phosphatase 2	0.042
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.040
Mdm4	transformed mouse 3T3 cell double minute 4	0.040
Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.040	Yeast
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.039
Foxc1	forkhead box C1	0.039
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.039
Per1	period homolog 1 (Drosophila)	0.039
Psen2	presenilin 2	0.038
Hdac1	histone deacetylase 1	0.038
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.038
Pou5f1	POU domain, class 5, transcription factor 1	0.035
Mecp2	methyl CpG binding protein 2	0.035
Grb10	growth factor receptor bound protein 10	0.035
Braf	Braf transforming gene	0.035
Mt1	metallothionein 1	0.034
Mef2a	myocyte enhancer factor 2A	0.034	Yeast
Rnf220	ring finger protein 220	0.033
Ubc	ubiquitin C	0.033
Ier2	immediate early response 2	0.033
Pnpla2	patatin-like phospholipase domain containing 2	0.032
Ncor2	nuclear receptor co-repressor 2	0.031
Sim1	single-minded homolog 1 (Drosophila)	0.030	Mouse
Foxo3	forkhead box O3	0.030	Worm
Mapkapk2	MAP kinase-activated protein kinase 2	0.030
Itga3	integrin alpha 3	0.028
Klf5	Kruppel-like factor 5	0.028
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.028
E2f1	E2F transcription factor 1	0.027
Sp1	trans-acting transcription factor 1	0.027
Yap1	yes-associated protein 1	0.026
Shh	sonic hedgehog	0.026
Atf4	activating transcription factor 4	0.025
Socs1	suppressor of cytokine signaling 1	0.025
Arnt	aryl hydrocarbon receptor nuclear translocator	0.024	Human
Errfi1	ERBB receptor feedback inhibitor 1	0.024
Nphs2	nephrosis 2 homolog, podocin (human)	0.024
Fosb	FBJ osteosarcoma oncogene B	0.023
Ntf3	neurotrophin 3	0.023
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.023
Mcl1	myeloid cell leukemia sequence 1	0.022
Trp73	transformation related protein 73	0.022	Fly
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.022
Prkci	protein kinase C, iota	0.022
Smad4	MAD homolog 4 (Drosophila)	0.022
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.021	Human Rat
Fzd4	frizzled homolog 4 (Drosophila)	0.020
Foxa2	forkhead box A2	0.019
Gata3	GATA binding protein 3	0.019
Epor	erythropoietin receptor	0.019
Sall4	sal-like 4 (Drosophila)	0.019
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.019
Msh2	mutS homolog 2 (E. coli)	0.018
Qk	quaking	0.018
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.018
Smad5	MAD homolog 5 (Drosophila)	0.018
Gja1	gap junction protein, alpha 1	0.017
Etv2	ets variant gene 2	0.017
Rara	retinoic acid receptor, alpha	0.017
Sfn	stratifin	0.017
Brca2	breast cancer 2	0.017
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.016
Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	0.016
Zfand5	zinc finger, AN1-type domain 5	0.016
Rasal1	RAS protein activator like 1 (GAP1 like)	0.016
Emx2	empty spiracles homolog 2 (Drosophila)	0.016
Smad1	MAD homolog 1 (Drosophila)	0.016
Nf1	neurofibromatosis 1	0.016
Esr2	estrogen receptor 2 (beta)	0.016
Lmx1b	LIM homeobox transcription factor 1 beta	0.016
Thra	thyroid hormone receptor alpha	0.016
Tgfb1	transforming growth factor, beta 1	0.016
Gata6	GATA binding protein 6	0.015
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.015
Amhr2	anti-Mullerian hormone type 2 receptor	0.014
Creb1	cAMP responsive element binding protein 1	0.014
Atm	ataxia telangiectasia mutated homolog (human)	0.014
Ncoa1	nuclear receptor coactivator 1	0.014
Fst	follistatin	0.014
Sun2	Sad1 and UNC84 domain containing 2	0.014
Emx1	empty spiracles homolog 1 (Drosophila)	0.014
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.014
Kl	klotho	0.014
Tcf4	transcription factor 4	0.014
Nab1	Ngfi-A binding protein 1	0.014
Mgea5	meningioma expressed antigen 5 (hyaluronidase)	0.013
Tead3	TEA domain family member 3	0.013
Luc7l2	LUC7-like 2 (S. cerevisiae)	0.013
Klf13	Kruppel-like factor 13	0.013
March7	membrane-associated ring finger (C3HC4) 7	0.013
Snrk	SNF related kinase	0.013
Mnt	max binding protein	0.013
Sall3	sal-like 3 (Drosophila)	0.013
Agtr1a	angiotensin II receptor, type 1a	0.013
Mapk9	mitogen-activated protein kinase 9	0.013	Yeast
Gadd45b	growth arrest and DNA-damage-inducible 45 beta	0.013
Kiss1	KiSS-1 metastasis-suppressor	0.013
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.013
Nfib	nuclear factor I/B	0.012
Dapk3	death-associated protein kinase 3	0.012
Per2	period homolog 2 (Drosophila)	0.012
Raf1	v-raf-leukemia viral oncogene 1	0.012
Sh2b3	SH2B adaptor protein 3	0.012
Foxk1	forkhead box K1	0.012
Klhl24	kelch-like 24 (Drosophila)	0.012
Prkce	protein kinase C, epsilon	0.012
Ifrd1	interferon-related developmental regulator 1	0.012
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.012
Adam17	a disintegrin and metallopeptidase domain 17	0.012
Tgfbr1	transforming growth factor, beta receptor I	0.012
Klf3	Kruppel-like factor 3 (basic)	0.011
Rapsn	receptor-associated protein of the synapse	0.011
Hipk3	homeodomain interacting protein kinase 3	0.011
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.011
Asxl1	additional sex combs like 1 (Drosophila)	0.011
Met	met proto-oncogene	0.011
Rora	RAR-related orphan receptor alpha	0.011
Ubl3	ubiquitin-like 3	0.011
Mef2d	myocyte enhancer factor 2D	0.011	Yeast
Ppard	peroxisome proliferator activator receptor delta	0.010
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.010
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.010
Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	0.010
Ncor1	nuclear receptor co-repressor 1	0.010