IMP

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Mus musculus

3 genes annotated in mouse

physiological muscle hypertrophy

The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "physiological muscle hypertrophy"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "physiological muscle hypertrophy" (in gray)

Name	Description	Probability	Func Analog Organism
Ctnnb1	catenin (cadherin associated protein), beta 1	0.905
Apc	adenomatosis polyposis coli	0.754
Axin1	axin 1	0.617
Agtr1a	angiotensin II receptor, type 1a	0.360
Lepr	leptin receptor	0.298
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.176
Lrrk2	leucine-rich repeat kinase 2	0.153
Lrp6	low density lipoprotein receptor-related protein 6	0.136
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.132
Egfr	epidermal growth factor receptor	0.119
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.112
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.108
Epas1	endothelial PAS domain protein 1	0.092
Gsk3b	glycogen synthase kinase 3 beta	0.089	Mouse
Hif1a	hypoxia inducible factor 1, alpha subunit	0.088
Kif1b	kinesin family member 1B	0.068
Vav3	vav 3 oncogene	0.065
Ncoa1	nuclear receptor coactivator 1	0.062
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.055
Mef2a	myocyte enhancer factor 2A	0.054
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.051
Pparg	peroxisome proliferator activated receptor gamma	0.049
Itgbl1	integrin, beta-like 1	0.049
Vegfa	vascular endothelial growth factor A	0.048
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.048
Smad3	MAD homolog 3 (Drosophila)	0.045
Srpx	sushi-repeat-containing protein	0.042
Slc23a2	solute carrier family 23 (nucleobase transporters), member 2	0.039
Kcne4	potassium voltage-gated channel, Isk-related subfamily, gene 4	0.039
Apoe	apolipoprotein E	0.039
Agtr2	angiotensin II receptor, type 2	0.038
Col16a1	collagen, type XVI, alpha 1	0.037
Adamts2	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2	0.037
Mtmr1	myotubularin related protein 1	0.036
Scn7a	sodium channel, voltage-gated, type VII, alpha	0.036
Braf	Braf transforming gene	0.036
Ptgs2	prostaglandin-endoperoxide synthase 2	0.033
Tgfb1	transforming growth factor, beta 1	0.032
Meox2	mesenchyme homeobox 2	0.031
Cpz	carboxypeptidase Z	0.031
Vav2	vav 2 oncogene	0.030
Igf1	insulin-like growth factor 1	0.030
Hoxd8	homeobox D8	0.029
Tfpi2	tissue factor pathway inhibitor 2	0.028
Umod	uromodulin	0.028
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.027
Mapk9	mitogen-activated protein kinase 9	0.027
Il6st	interleukin 6 signal transducer	0.027
Egln3	EGL nine homolog 3 (C. elegans)	0.027
Adrb2	adrenergic receptor, beta 2	0.026
Kpna1	karyopherin (importin) alpha 1	0.026
Vdr	vitamin D receptor	0.026
Col6a3	collagen, type VI, alpha 3	0.026
Htt	huntingtin	0.026
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.026
Adam17	a disintegrin and metallopeptidase domain 17	0.026
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.026
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.025
Fbxo43	F-box protein 43	0.025
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.025
Col11a1	collagen, type XI, alpha 1	0.024
Thbs2	thrombospondin 2	0.024
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.024
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.024
Nf2	neurofibromatosis 2	0.023
Wnk4	WNK lysine deficient protein kinase 4	0.023
Slc12a1	solute carrier family 12, member 1	0.023
Hipk3	homeodomain interacting protein kinase 3	0.023
Gsk3a	glycogen synthase kinase 3 alpha	0.022
Dpt	dermatopontin	0.022
Eln	elastin	0.022
Fcna	ficolin A	0.022
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.022
Arid1b	AT rich interactive domain 1B (SWI-like)	0.022
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.022
Pde4d	phosphodiesterase 4D, cAMP specific	0.021
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.021
Angpt4	angiopoietin 4	0.021
Gatad2b	GATA zinc finger domain containing 2B	0.020
Tnxb	tenascin XB	0.020
Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	0.020
Cxcl12	chemokine (C-X-C motif) ligand 12	0.020
Crh	corticotropin releasing hormone	0.019
Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.019
Col4a4	collagen, type IV, alpha 4	0.019
Nos3	nitric oxide synthase 3, endothelial cell	0.019
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.019
Crhr1	corticotropin releasing hormone receptor 1	0.019
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.019
C1s	complement component 1, s subcomponent	0.018
Rab10	RAB10, member RAS oncogene family	0.018
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.018
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.017
Klhl24	kelch-like 24 (Drosophila)	0.017
Fibin	fin bud initiation factor homolog (zebrafish)	0.017
Pnpla2	patatin-like phospholipase domain containing 2	0.017
C1qtnf3	C1q and tumor necrosis factor related protein 3	0.017
Adam18	a disintegrin and metallopeptidase domain 18	0.017
Fgf7	fibroblast growth factor 7	0.017
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.017
Arl8b	ADP-ribosylation factor-like 8B	0.016
Tnrc6b	trinucleotide repeat containing 6b	0.016
Dmd	dystrophin, muscular dystrophy	0.016
Lep	leptin	0.016
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.016
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.016
Shoc2	soc-2 (suppressor of clear) homolog (C. elegans)	0.016
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.016
Fbln5	fibulin 5	0.016
Vmn1r14	vomeronasal 1 receptor 14	0.016
Tll1	tolloid-like	0.015
Fbxw11	F-box and WD-40 domain protein 11	0.015
Cpxm2	carboxypeptidase X 2 (M14 family)	0.015
Col1a2	collagen, type I, alpha 2	0.015
Psen1	presenilin 1	0.015
Egln1	EGL nine homolog 1 (C. elegans)	0.015
Vhl	von Hippel-Lindau tumor suppressor	0.015
C1qtnf2	C1q and tumor necrosis factor related protein 2	0.015
Tnmd	tenomodulin	0.015
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.015
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.015
Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1	0.015
Klf7	Kruppel-like factor 7 (ubiquitous)	0.015
Mfap5	microfibrillar associated protein 5	0.014
Adamts5	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)	0.014
Mfap4	microfibrillar-associated protein 4	0.014
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.014
Usp25	ubiquitin specific peptidase 25	0.014
Abhd5	abhydrolase domain containing 5	0.014
4930544G11Rik	RIKEN cDNA 4930544G11 gene	0.014
Trpm8	transient receptor potential cation channel, subfamily M, member 8	0.014
Fhl5	four and a half LIM domains 5	0.014
Klhl10	kelch-like 10 (Drosophila)	0.014
Ptgfr	prostaglandin F receptor	0.013
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.013
Masp1	mannan-binding lectin serine peptidase 1	0.013
Adam24	a disintegrin and metallopeptidase domain 24 (testase 1)	0.013
Tspyl1	testis-specific protein, Y-encoded-like 1	0.013
Serpina3a	serine (or cysteine) peptidase inhibitor, clade A, member 3A	0.013
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.013
Ttc23l	tetratricopeptide repeat domain 23-like	0.013
Mas1	MAS1 oncogene	0.013
Pdlim3	PDZ and LIM domain 3	0.013
Lce1l	late cornified envelope 1L	0.013
Eya4	eyes absent 4 homolog (Drosophila)	0.013
Nnmt	nicotinamide N-methyltransferase	0.013
Nek11	NIMA (never in mitosis gene a)-related expressed kinase 11	0.013
Tcf21	transcription factor 21	0.013
Abi3bp	ABI gene family, member 3 (NESH) binding protein	0.013
Gdf10	growth differentiation factor 10	0.013
Med13l	mediator complex subunit 13-like	0.013
Lif	leukemia inhibitory factor	0.013
Speer4a	spermatogenesis associated glutamate (E)-rich protein 4a	0.013
Comp	cartilage oligomeric matrix protein	0.012
Spinkl	serine protease inhibitor, Kazal type-like	0.012
Smad4	MAD homolog 4 (Drosophila)	0.012
Fap	fibroblast activation protein	0.012
Cst10	cystatin 10 (chondrocytes)	0.012
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.012
Vmn1r29	vomeronasal 1 receptor 29	0.012
Tpsb2	tryptase beta 2	0.012
Tshz2	teashirt zinc finger family member 2	0.012
Prl2c1	Prolactin family 2, subfamily c, member 1	0.012
Cts6	cathepsin 6	0.012
Prelp	proline arginine-rich end leucine-rich repeat	0.012
Smad2	MAD homolog 2 (Drosophila)	0.012
Cspg4	chondroitin sulfate proteoglycan 4	0.012
Sardh	sarcosine dehydrogenase	0.012
Folr2	folate receptor 2 (fetal)	0.012
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.012
Ccnd1	cyclin D1	0.012
Cpd	carboxypeptidase D	0.012
Glipr1l2	GLI pathogenesis-related 1 like 2	0.012	Mouse
Postn	periostin, osteoblast specific factor	0.012
Pcdhb18	protocadherin beta 18	0.012
Flt4	FMS-like tyrosine kinase 4	0.012
Smoc2	SPARC related modular calcium binding 2	0.012
Col15a1	collagen, type XV, alpha 1	0.012
Ces2g	carboxylesterase 2G	0.012
Klf3	Kruppel-like factor 3 (basic)	0.012
Mrgprf	MAS-related GPR, member F	0.011
Fmo1	flavin containing monooxygenase 1	0.011
1500015O10Rik	RIKEN cDNA 1500015O10 gene	0.011
Magea5	melanoma antigen, family A, 5	0.011
Pcdhb7	protocadherin beta 7	0.011
Nos2	nitric oxide synthase 2, inducible	0.011
Gm568	predicted gene 568	0.011
Ltbp2	latent transforming growth factor beta binding protein 2	0.011
Wisp1	WNT1 inducible signaling pathway protein 1	0.011
4930403N07Rik	RIKEN cDNA 4930403N07 gene	0.011
Olfr749	olfactory receptor 749	0.011
Taok1	TAO kinase 1	0.011
Fbln7	fibulin 7	0.011
Atp6v1c2	ATPase, H+ transporting, lysosomal V1 subunit C2	0.011
Zswim6	zinc finger, SWIM domain containing 6	0.011
Adamts15	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15	0.011
Cd248	CD248 antigen, endosialin	0.011
Tmem8c	transmembrane protein 8C	0.011
Prnd	prion protein dublet	0.011
Sctr	secretin receptor	0.011
Chrdl1	chordin-like 1	0.011
Homer1	homer homolog 1 (Drosophila)	0.011
Srpx2	sushi-repeat-containing protein, X-linked 2	0.011
Pum1	pumilio 1 (Drosophila)	0.011
Osr2	odd-skipped related 2 (Drosophila)	0.011
Vmn1r30	vomeronasal 1 receptor 30	0.011
Aplnr	apelin receptor	0.011
Tgfbr1	transforming growth factor, beta receptor I	0.011
Pabpc5	poly(A) binding protein, cytoplasmic 5	0.010
1700123K08Rik	RIKEN cDNA 1700123K08 gene	0.010
BC026439	cDNA sequence BC026439	0.010
Npepps	aminopeptidase puromycin sensitive	0.010
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.010
C2	complement component 2 (within H-2S)	0.010
Vmn1r15	vomeronasal 1 receptor 15	0.010
Cux1	cut-like homeobox 1	0.010
Gpc6	glypican 6	0.010
Angptl7	angiopoietin-like 7	0.010
Itga8	integrin alpha 8	0.010
Pcdhb4	protocadherin beta 4	0.010
Crlf1	cytokine receptor-like factor 1	0.010
Pear1	platelet endothelial aggregation receptor 1	0.010
Ptgs1	prostaglandin-endoperoxide synthase 1	0.010
Cilp	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	0.010
Prss52	protease, serine, 52	0.010
Defb5	defensin beta 5	0.010
Pkn2	protein kinase N2	0.010
Krtap3-2	keratin associated protein 3-2	0.010
Wnt2	wingless-related MMTV integration site 2	0.010
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.010
Slc15a5	solute carrier family 15, member 5	0.010