IMP

Process View

Mus musculus

12 genes annotated in mouse

Multi-species View

sister chromatid cohesion

GO:0007062

The cell cycle process in which the sister chromatids of a replicated chromosome are associated with each other.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "sister chromatid cohesion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "sister chromatid cohesion" (in gray)

Name	Description	Probability	Func Analog Organism
Smc3	structural maintenace of chromosomes 3	0.990	Human Yeast Zebrafish
Smc1a	structural maintenance of chromosomes 1A	0.974	Human Yeast Mouse
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.598
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.563
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.455
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.419
Rb1	retinoblastoma 1	0.390	Human
Gsk3b	glycogen synthase kinase 3 beta	0.277
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.258
Pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.234
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.217
Ccne1	cyclin E1	0.206
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.198	Human Worm
Pole	polymerase (DNA directed), epsilon	0.185	Yeast
Cdt1	chromatin licensing and DNA replication factor 1	0.166
Ccnf	cyclin F	0.165
Mecp2	methyl CpG binding protein 2	0.160
Cdca5	cell division cycle associated 5	0.151
Birc5	baculoviral IAP repeat-containing 5	0.149
Timeless	timeless homolog (Drosophila)	0.136	Worm
Trp53	transformation related protein 53	0.125
Cdk4	cyclin-dependent kinase 4	0.125
Pten	phosphatase and tensin homolog	0.122
Ccna2	cyclin A2	0.118
Kif22	kinesin family member 22	0.104
Rybp	RING1 and YY1 binding protein	0.102
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.102
Ccnb1	cyclin B1	0.101
Lig1	ligase I, DNA, ATP-dependent	0.092
Mybl2	myeloblastosis oncogene-like 2	0.085
Ccnb2	cyclin B2	0.083
Rnf111	ring finger 111	0.083
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.080	Fly
Brca1	breast cancer 1	0.070
Aurkb	aurora kinase B	0.068
Atm	ataxia telangiectasia mutated homolog (human)	0.067
Ckap2	cytoskeleton associated protein 2	0.067
Clspn	claspin homolog (Xenopus laevis)	0.065
Smad4	MAD homolog 4 (Drosophila)	0.064
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.064
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.062
Plk1	polo-like kinase 1 (Drosophila)	0.062
Prim1	DNA primase, p49 subunit	0.062
Cdk1	cyclin-dependent kinase 1	0.060	Yeast
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.060
Msh2	mutS homolog 2 (E. coli)	0.060
Rbl2	retinoblastoma-like 2	0.060	Fly
Pou5f1	POU domain, class 5, transcription factor 1	0.056
Kif20a	kinesin family member 20A	0.053
Kif11	kinesin family member 11	0.052
Brca2	breast cancer 2	0.050
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.049
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.048
Cenpe	centromere protein E	0.047
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.047
Rbl1	retinoblastoma-like 1 (p107)	0.047	Fly
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.044
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.044
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.041
Mdm4	transformed mouse 3T3 cell double minute 4	0.040
Sgol1	shugoshin-like 1 (S. pombe)	0.040
Cenpn	centromere protein N	0.037
Tk1	thymidine kinase 1	0.036
Cnot6l	CCR4-NOT transcription complex, subunit 6-like	0.035
Jarid2	jumonji, AT rich interactive domain 2	0.035
Cenpf	centromere protein F	0.035
Crebbp	CREB binding protein	0.034
Gtse1	G two S phase expressed protein 1	0.034
Nbn	nibrin	0.034
Tcfcp2l1	transcription factor CP2-like 1	0.033
Nab2	Ngfi-A binding protein 2	0.033
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.033
Ints9	integrator complex subunit 9	0.032
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.031
Rfc2	replication factor C (activator 1) 2	0.031
Aurka	aurora kinase A	0.030
Melk	maternal embryonic leucine zipper kinase	0.030
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.029
Nanog	Nanog homeobox	0.029
Rfc5	replication factor C (activator 1) 5	0.028	Yeast
Kif2c	kinesin family member 2C	0.028
Orc1	origin recognition complex, subunit 1	0.026
Chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.026
Tcf19	transcription factor 19	0.026
Ube2c	ubiquitin-conjugating enzyme E2C	0.026
Stil	Scl/Tal1 interrupting locus	0.025
Mms22l	MMS22-like, DNA repair protein	0.025
Ncaph	non-SMC condensin I complex, subunit H	0.024
Igh	immunoglobulin heavy chain complex	0.024
Racgap1	Rac GTPase-activating protein 1	0.023
Eme1	essential meiotic endonuclease 1 homolog 1 (S. pombe)	0.023
Haus5	HAUS augmin-like complex, subunit 5	0.022
Haus4	HAUS augmin-like complex, subunit 4	0.022
Tmem48	transmembrane protein 48	0.022
Apc	adenomatosis polyposis coli	0.022
Kif4	kinesin family member 4	0.022
Ercc6l	excision repair cross-complementing rodent repair deficiency complementation group 6 - like	0.022
Ep400	E1A binding protein p400	0.022
Tert	telomerase reverse transcriptase	0.021
Tcf3	transcription factor 3	0.021
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.021	Human Worm
Smc4	structural maintenance of chromosomes 4	0.021
Cdca8	cell division cycle associated 8	0.021
Vrk1	vaccinia related kinase 1	0.021
Rfc1	replication factor C (activator 1) 1	0.021
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.020
Lrp5	low density lipoprotein receptor-related protein 5	0.020
Smad6	MAD homolog 6 (Drosophila)	0.020
Ccdc99	coiled-coil domain containing 99	0.020
Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.020
E2f1	E2F transcription factor 1	0.020
Smad7	MAD homolog 7 (Drosophila)	0.020
Prc1	protein regulator of cytokinesis 1	0.020
Cdk2	cyclin-dependent kinase 2	0.019	Yeast
Blm	Bloom syndrome, RecQ helicase-like	0.019
Dtl	denticleless homolog (Drosophila)	0.019
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.019
Ccnd1	cyclin D1	0.019
Efnb2	ephrin B2	0.019
Lef1	lymphoid enhancer binding factor 1	0.018
E2f8	E2F transcription factor 8	0.018
Pkdcc	protein kinase domain containing, cytoplasmic	0.018
Casp3	caspase 3	0.018
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.018
Incenp	inner centromere protein	0.018
Sox4	SRY-box containing gene 4	0.017
Gins1	GINS complex subunit 1 (Psf1 homolog)	0.017
Ppih	peptidyl prolyl isomerase H	0.017
Wapal	wings apart-like homolog (Drosophila)	0.017
Xrcc6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.017
Rrm1	ribonucleotide reductase M1	0.017
Pask	PAS domain containing serine/threonine kinase	0.017
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.017
Gsg2	germ cell-specific gene 2	0.016	Human
Ncapg	non-SMC condensin I complex, subunit G	0.016
Baz2a	bromodomain adjacent to zinc finger domain, 2A	0.016
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.016
Rpa2	replication protein A2	0.016
Haus1	HAUS augmin-like complex, subunit 1	0.016
Mdm2	transformed mouse 3T3 cell double minute 2	0.016
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.015
Kdm2b	lysine (K)-specific demethylase 2B	0.015
Rqcd1	rcd1 (required for cell differentiation) homolog 1 (S. pombe)	0.015
Lrp6	low density lipoprotein receptor-related protein 6	0.014
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.014
Rad50	RAD50 homolog (S. cerevisiae)	0.014
Mcm10	minichromosome maintenance deficient 10 (S. cerevisiae)	0.014
Wrn	Werner syndrome homolog (human)	0.014
Kars	lysyl-tRNA synthetase	0.014
Rec8	REC8 homolog (yeast)	0.014
4930427A07Rik	RIKEN cDNA 4930427A07 gene	0.014
Dtymk	deoxythymidylate kinase	0.014
H2afx	H2A histone family, member X	0.014
Msh6	mutS homolog 6 (E. coli)	0.013
Dmtf1	cyclin D binding myb-like transcription factor 1	0.013
Rcc1	regulator of chromosome condensation 1	0.013
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.013
Kif23	kinesin family member 23	0.013
Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.013
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.013
Rad51ap1	RAD51 associated protein 1	0.013
Skiv2l	superkiller viralicidic activity 2-like (S. cerevisiae)	0.013
Cenpi	centromere protein I	0.013
Pkd1	polycystic kidney disease 1 homolog	0.013
Mcm6	minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)	0.013
Capn7	calpain 7	0.013
Rrm2	ribonucleotide reductase M2	0.013
Rfc3	replication factor C (activator 1) 3	0.013	Yeast
Cbx8	chromobox homolog 8 (Drosophila Pc class)	0.013
Bmi1	Bmi1 polycomb ring finger oncogene	0.013
Rsf1	remodeling and spacing factor 1	0.012
Ldb1	LIM domain binding 1	0.012
Ncapd2	non-SMC condensin I complex, subunit D2	0.012
Nubp1	nucleotide binding protein 1	0.012
Zmym2	zinc finger, MYM-type 2	0.012
1810009A15Rik	RIKEN cDNA 1810009A15 gene	0.012
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.012
Dna2	DNA replication helicase 2 homolog (yeast)	0.012
Rad51	RAD51 homolog (S. cerevisiae)	0.012
Scaf11	SR-related CTD-associated factor 11	0.012
Dcaf8	DDB1 and CUL4 associated factor 8	0.012
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.012
Nup43	nucleoporin 43	0.012
Cdc25a	cell division cycle 25 homolog A (S. pombe)	0.012
Cenpa	centromere protein A	0.012
Cul4b	cullin 4B	0.012
Zeb1	zinc finger E-box binding homeobox 1	0.011
Dut	deoxyuridine triphosphatase	0.011
Tmpo	thymopoietin	0.011
Cdc45	cell division cycle 45 homolog (S. cerevisiae)	0.011
Mns1	meiosis-specific nuclear structural protein 1	0.011
Ccng2	cyclin G2	0.011
Ep300	E1A binding protein p300	0.011
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.011
Ncapd3	non-SMC condensin II complex, subunit D3	0.011
Rad21	RAD21 homolog (S. pombe)	0.011
Arid2	AT rich interactive domain 2 (ARID, RFX-like)	0.011
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.011
Espl1	extra spindle poles-like 1 (S. cerevisiae)	0.011
Mael	maelstrom homolog (Drosophila)	0.011
Zfp871	zinc finger protein 871	0.011
Nudt1	nudix (nucleoside diphosphate linked moiety X)-type motif 1	0.011
Txndc16	thioredoxin domain containing 16	0.011
Pum2	pumilio 2 (Drosophila)	0.011
Iqgap3	IQ motif containing GTPase activating protein 3	0.010
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.010
Pcgf2	polycomb group ring finger 2	0.010
Tex11	testis expressed gene 11	0.010
Ttf2	transcription termination factor, RNA polymerase II	0.010
Spag5	sperm associated antigen 5	0.010