IMP

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of cardiac muscle tissue growth"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of cardiac muscle tissue growth" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Pax2	paired box gene 2	1.000
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	1.000
Fgf8	fibroblast growth factor 8	1.000
Tbx3	T-box 3	1.000	Mouse
Tbx1	T-box 1	0.997	Mouse
Foxc1	forkhead box C1	0.996
Notch1	Notch gene homolog 1 (Drosophila)	0.996
Pitx2	paired-like homeodomain transcription factor 2	0.995
Jag1	jagged 1	0.995
Hand2	heart and neural crest derivatives expressed transcript 2	0.992
Gata4	GATA binding protein 4	0.990
Ntf3	neurotrophin 3	0.988
Hoxa1	homeobox A1	0.988
Efnb2	ephrin B2	0.987
Pax3	paired box gene 3	0.975
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.975
Gli3	GLI-Kruppel family member GLI3	0.975
Zfpm2	zinc finger protein, multitype 2	0.951
Bmp4	bone morphogenetic protein 4	0.951
Wt1	Wilms tumor 1 homolog	0.931
Hoxa13	homeobox A13	0.924
Rxra	retinoid X receptor alpha	0.918
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.900
Lhx1	LIM homeobox protein 1	0.880
Gata6	GATA binding protein 6	0.879
Nodal	nodal	0.865	Mouse
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.863	Mouse
Notch2	Notch gene homolog 2 (Drosophila)	0.856	Mouse
Ret	ret proto-oncogene	0.855
Lmx1a	LIM homeobox transcription factor 1 alpha	0.854
Tbx2	T-box 2	0.792
Tcf21	transcription factor 21	0.786
Pitx1	paired-like homeodomain transcription factor 1	0.781
Nos3	nitric oxide synthase 3, endothelial cell	0.775
Fgfr1	fibroblast growth factor receptor 1	0.750
Hand1	heart and neural crest derivatives expressed transcript 1	0.744
Fgf10	fibroblast growth factor 10	0.742	Mouse
Hoxa11	homeobox A11	0.730
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.721	Mouse
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.720
Hoxd11	homeobox D11	0.696
Chd7	chromodomain helicase DNA binding protein 7	0.690
Sox9	SRY-box containing gene 9	0.671
Foxc2	forkhead box C2	0.624
Isl1	ISL1 transcription factor, LIM/homeodomain	0.612
Nog	noggin	0.610
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.575
Wnt10b	wingless related MMTV integration site 10b	0.562	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.547
Dll1	delta-like 1 (Drosophila)	0.547
Bdnf	brain derived neurotrophic factor	0.516
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.498
Gja3	gap junction protein, alpha 3	0.480
Dll4	delta-like 4 (Drosophila)	0.480
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.474
Fgf3	fibroblast growth factor 3	0.474	Mouse
Col13a1	collagen, type XIII, alpha 1	0.459
Ctnnb1	catenin (cadherin associated protein), beta 1	0.458
Gbx2	gastrulation brain homeobox 2	0.452
Vegfa	vascular endothelial growth factor A	0.450
Wnt3a	wingless-related MMTV integration site 3A	0.421	Mouse
Meox2	mesenchyme homeobox 2	0.415
Trp63	transformation related protein 63	0.405
Tbx5	T-box 5	0.399
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.362
Chrd	chordin	0.359
Sox7	SRY-box containing gene 7	0.353
Pax8	paired box gene 8	0.353
Fgf18	fibroblast growth factor 18	0.337
Msx2	homeobox, msh-like 2	0.320
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.314
Pten	phosphatase and tensin homolog	0.304
Mef2c	myocyte enhancer factor 2C	0.302
Gata3	GATA binding protein 3	0.295	Mouse
Foxf1a	forkhead box F1a	0.292
Lef1	lymphoid enhancer binding factor 1	0.288
Twist2	twist homolog 2 (Drosophila)	0.283
Gli2	GLI-Kruppel family member GLI2	0.268
Rarg	retinoic acid receptor, gamma	0.249
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.247
Gdnf	glial cell line derived neurotrophic factor	0.243
Bcl2	B-cell leukemia/lymphoma 2	0.237
Otx1	orthodenticle homolog 1 (Drosophila)	0.229
Lama5	laminin, alpha 5	0.228
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.206
She	src homology 2 domain-containing transforming protein E	0.200
Gli1	GLI-Kruppel family member GLI1	0.199
Tbx15	T-box 15	0.186	Mouse
Otx2	orthodenticle homolog 2 (Drosophila)	0.182
Hmx3	H6 homeobox 3	0.173
Foxn1	forkhead box N1	0.173
Fgf15	fibroblast growth factor 15	0.173
Hoxd13	homeobox D13	0.170
Bmp5	bone morphogenetic protein 5	0.169	Mouse
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.169	Mouse
Ar	androgen receptor	0.163
Apc	adenomatosis polyposis coli	0.163
Tgfb2	transforming growth factor, beta 2	0.161
Vangl2	vang-like 2 (van gogh, Drosophila)	0.160
Padi3	peptidyl arginine deiminase, type III	0.158
Emx2	empty spiracles homolog 2 (Drosophila)	0.157
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.155
Snai1	snail homolog 1 (Drosophila)	0.155
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.152
Wnt7a	wingless-related MMTV integration site 7A	0.152	Mouse
Wnt2b	wingless related MMTV integration site 2b	0.152	Mouse
Gdf5	growth differentiation factor 5	0.149	Mouse
Foxf2	forkhead box F2	0.146
Hoxa10	homeobox A10	0.142
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.140
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.139
Prrx2	paired related homeobox 2	0.136
Msx1	homeobox, msh-like 1	0.134
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.133
Egfr	epidermal growth factor receptor	0.132	Mouse
Sox17	SRY-box containing gene 17	0.130
Pou5f1	POU domain, class 5, transcription factor 1	0.130
Gata5	GATA binding protein 5	0.129	Mouse
Ptk7	PTK7 protein tyrosine kinase 7	0.125
Emid2	EMI domain containing 2	0.125
Alx4	aristaless-like homeobox 4	0.124
Zic3	zinc finger protein of the cerebellum 3	0.123
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.122
Wnt3	wingless-related MMTV integration site 3	0.121	Mouse
Fgfr3	fibroblast growth factor receptor 3	0.118	Mouse
Bnc1	basonuclin 1	0.117
Adra2b	adrenergic receptor, alpha 2b	0.116
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.114
Wnt9b	wingless-type MMTV integration site 9B	0.113	Mouse
Hes1	hairy and enhancer of split 1 (Drosophila)	0.113
Acan	aggrecan	0.112
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.112
Wnt11	wingless-related MMTV integration site 11	0.112	Mouse
Npr3	natriuretic peptide receptor 3	0.112
Wnt6	wingless-related MMTV integration site 6	0.110	Mouse
Tal1	T-cell acute lymphocytic leukemia 1	0.108
Rarb	retinoic acid receptor, beta	0.106
Prc1	protein regulator of cytokinesis 1	0.103
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.101
Foxg1	forkhead box G1	0.099
Hdac4	histone deacetylase 4	0.098
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.097
Lmx1b	LIM homeobox transcription factor 1 beta	0.095
Foxb1	forkhead box B1	0.093
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.093
Alx3	aristaless-like homeobox 3	0.092
Sox2	SRY-box containing gene 2	0.091
Tcfap2a	transcription factor AP-2, alpha	0.090
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.090
Dlx5	distal-less homeobox 5	0.086
Btbd17	BTB (POZ) domain containing 17	0.086
En1	engrailed 1	0.084
Edn3	endothelin 3	0.081
Kcnk3	potassium channel, subfamily K, member 3	0.076
Gpc3	glypican 3	0.076
Bdkrb2	bradykinin receptor, beta 2	0.075
Eya1	eyes absent 1 homolog (Drosophila)	0.073
Epha1	Eph receptor A1	0.072
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.071
Angpt4	angiopoietin 4	0.070
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.069
Axin2	axin2	0.068
Amhr2	anti-Mullerian hormone type 2 receptor	0.067
Pcdh12	protocadherin 12	0.064
Psen1	presenilin 1	0.064
Pthlh	parathyroid hormone-like peptide	0.063
Myl3	myosin, light polypeptide 3	0.061
Nf1	neurofibromatosis 1	0.061
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.060
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.060	Mouse
Tbx4	T-box 4	0.059	Mouse
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.059
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.059
Foxb2	forkhead box B2	0.059
Tbx20	T-box 20	0.059
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.059
Mecom	MDS1 and EVI1 complex locus	0.058
Gja5	gap junction protein, alpha 5	0.056
Prrx1	paired related homeobox 1	0.055
Sult5a1	sulfotransferase family 5A, member 1	0.054
Nkx2-1	NK2 homeobox 1	0.053
Mesp1	mesoderm posterior 1	0.053
Foxi1	forkhead box I1	0.052
Tcl1	T-cell lymphoma breakpoint 1	0.052
Socs1	suppressor of cytokine signaling 1	0.051
Prdm6	PR domain containing 6	0.050
Notch3	Notch gene homolog 3 (Drosophila)	0.050	Mouse
Crhr2	corticotropin releasing hormone receptor 2	0.050
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.049
Foxa2	forkhead box A2	0.048
Tgfbr3	transforming growth factor, beta receptor III	0.048
Adra1a	adrenergic receptor, alpha 1a	0.046
Gdf6	growth differentiation factor 6	0.046	Mouse
Hrc	histidine rich calcium binding protein	0.045
Phox2a	paired-like homeobox 2a	0.045
Rspo1	R-spondin homolog (Xenopus laevis)	0.044
Shox2	short stature homeobox 2	0.044
Epha4	Eph receptor A4	0.044
Kl	klotho	0.044
Acvr1	activin A receptor, type 1	0.044
Zeb1	zinc finger E-box binding homeobox 1	0.043
Dhh	desert hedgehog	0.042
Esr2	estrogen receptor 2 (beta)	0.041
Irx4	Iroquois related homeobox 4 (Drosophila)	0.041
Jag2	jagged 2	0.040
Nobox	NOBOX oogenesis homeobox	0.038
Scn5a	sodium channel, voltage-gated, type V, alpha	0.038
Hdac7	histone deacetylase 7	0.037
Fgf5	fibroblast growth factor 5	0.037	Mouse
Ptgs2	prostaglandin-endoperoxide synthase 2	0.037
Hdac5	histone deacetylase 5	0.037
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.036
Sftpb	surfactant associated protein B	0.036
Ryr2	ryanodine receptor 2, cardiac	0.036
Col4a3	collagen, type IV, alpha 3	0.035
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.035
Barx1	BarH-like homeobox 1	0.035
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.035
Klf3	Kruppel-like factor 3 (basic)	0.034
Heyl	hairy/enhancer-of-split related with YRPW motif-like	0.034	Mouse
Zfp651	zinc finger protein 651	0.034
Ptprb	protein tyrosine phosphatase, receptor type, B	0.034
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.033
Sim2	single-minded homolog 2 (Drosophila)	0.033
Pitx3	paired-like homeodomain transcription factor 3	0.032
T	brachyury	0.032	Mouse
Clic3	chloride intracellular channel 3	0.032
Phox2b	paired-like homeobox 2b	0.032
Hoxc9	homeobox C9	0.031
Hoxc6	homeobox C6	0.031
Nrg1	neuregulin 1	0.031	Human
Wnt9a	wingless-type MMTV integration site 9A	0.031	Mouse
Fzd10	frizzled homolog 10 (Drosophila)	0.031
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.031
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.030
Adrb1	adrenergic receptor, beta 1	0.030	Rat
Edar	ectodysplasin-A receptor	0.030
Gja1	gap junction protein, alpha 1	0.030
Ptgfr	prostaglandin F receptor	0.029
Itga3	integrin alpha 3	0.029
Lrp6	low density lipoprotein receptor-related protein 6	0.029
Amh	anti-Mullerian hormone	0.029
Ntf5	neurotrophin 5	0.028
Hoxd9	homeobox D9	0.028
Gdf3	growth differentiation factor 3	0.027
Nes	nestin	0.027
Art5	ADP-ribosyltransferase 5	0.027
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.026
Sall4	sal-like 4 (Drosophila)	0.026
Sox10	SRY-box containing gene 10	0.026
Rem1	rad and gem related GTP binding protein 1	0.026
Hoxb6	homeobox B6	0.026
Nppa	natriuretic peptide type A	0.025
Hoxb4	homeobox B4	0.025
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.025
Mpl	myeloproliferative leukemia virus oncogene	0.025
Htra3	HtrA serine peptidase 3	0.024
Osr1	odd-skipped related 1 (Drosophila)	0.024
Ppara	peroxisome proliferator activated receptor alpha	0.024
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.023
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.023
Mef2d	myocyte enhancer factor 2D	0.023	Mouse
Foxd3	forkhead box D3	0.023
Oprd1	opioid receptor, delta 1	0.023
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.023
Rnf2	ring finger protein 2	0.023
Des	desmin	0.023
Tcfap2c	transcription factor AP-2, gamma	0.022
Ptf1a	pancreas specific transcription factor, 1a	0.022
Pax9	paired box gene 9	0.022
Npas1	neuronal PAS domain protein 1	0.022
Sh3pxd2a	SH3 and PX domains 2A	0.021
Nfia	nuclear factor I/A	0.021
Smyd1	SET and MYND domain containing 1	0.021
Tbx10	T-box 10	0.021	Mouse
Evx1	even skipped homeotic gene 1 homolog	0.021
Zfp503	zinc finger protein 503	0.021
Sox18	SRY-box containing gene 18	0.020
Efnb1	ephrin B1	0.020
Wnt1	wingless-related MMTV integration site 1	0.020	Mouse
Prnp	prion protein	0.020
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.019
Egfl7	EGF-like domain 7	0.019
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.019
Smad7	MAD homolog 7 (Drosophila)	0.019
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.019
Scube1	signal peptide, CUB domain, EGF-like 1	0.018
Srms	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	0.018
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.018
Epas1	endothelial PAS domain protein 1	0.018
Alx1	ALX homeobox 1	0.017
Adrb3	adrenergic receptor, beta 3	0.017
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.017
Pou3f1	POU domain, class 3, transcription factor 1	0.017
Smo	smoothened homolog (Drosophila)	0.017
Atoh8	atonal homolog 8 (Drosophila)	0.017
Dlx4	distal-less homeobox 4	0.017
Hoxd1	homeobox D1	0.017
Dnase1l2	deoxyribonuclease 1-like 2	0.017
Gsc	goosecoid homeobox	0.017
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.017
Neurog1	neurogenin 1	0.017
Fgfbp1	fibroblast growth factor binding protein 1	0.016
Spry4	sprouty homolog 4 (Drosophila)	0.016
Pgr	progesterone receptor	0.016
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.016
Tead4	TEA domain family member 4	0.016
Ncr1	natural cytotoxicity triggering receptor 1	0.016
Rgnef	Rho-guanine nucleotide exchange factor	0.016
Fzd4	frizzled homolog 4 (Drosophila)	0.016
Vipr2	vasoactive intestinal peptide receptor 2	0.016
En2	engrailed 2	0.015
Pou4f2	POU domain, class 4, transcription factor 2	0.015
Tal2	T-cell acute lymphocytic leukemia 2	0.015
Cer1	cerberus 1 homolog (Xenopus laevis)	0.015
Usp43	ubiquitin specific peptidase 43	0.015
Esr1	estrogen receptor 1 (alpha)	0.015
Moxd2	monooxygenase, DBH-like 2	0.015
Epha3	Eph receptor A3	0.015
Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1	0.015
Fzd1	frizzled homolog 1 (Drosophila)	0.015
Pofut1	protein O-fucosyltransferase 1	0.015
Wnt4	wingless-related MMTV integration site 4	0.015	Mouse
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.015
Krt35	keratin 35	0.015
Hoxa2	homeobox A2	0.015
Ccna2	cyclin A2	0.014
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.014
Efna2	ephrin A2	0.014
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.014
Cdh13	cadherin 13	0.014
Uncx	UNC homeobox	0.014
Bik	BCL2-interacting killer	0.014
Ppl	periplakin	0.014
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.014
Nat3	N-acetyltransferase 3	0.014
Fzd6	frizzled homolog 6 (Drosophila)	0.014
Msi1	Musashi homolog 1(Drosophila)	0.014
Foxh1	forkhead box H1	0.014
Mgat3	mannoside acetylglucosaminyltransferase 3	0.014
Lmod1	leiomodin 1 (smooth muscle)	0.013
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.013
Emx1	empty spiracles homolog 1 (Drosophila)	0.013
Ppyr1	pancreatic polypeptide receptor 1	0.013
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.013
Ptprd	protein tyrosine phosphatase, receptor type, D	0.013
Runx3	runt related transcription factor 3	0.013
Hoxb1	homeobox B1	0.013
Kcnk2	potassium channel, subfamily K, member 2	0.013
Onecut1	one cut domain, family member 1	0.013
Il12a	interleukin 12a	0.013
Lepr	leptin receptor	0.013
Chrm4	cholinergic receptor, muscarinic 4	0.012
Emp2	epithelial membrane protein 2	0.012
Adcy4	adenylate cyclase 4	0.012
Fmn1	formin 1	0.012
Cdx1	caudal type homeobox 1	0.012
Fut7	fucosyltransferase 7	0.012
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.012
Pax7	paired box gene 7	0.012
Adcy8	adenylate cyclase 8	0.012
Fgf9	fibroblast growth factor 9	0.012
Chrdl2	chordin-like 2	0.012
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.012
Angpt1	angiopoietin 1	0.012
Msx3	homeobox, msh-like 3	0.012
Tnnt3	troponin T3, skeletal, fast	0.012
Col22a1	collagen, type XXII, alpha 1	0.012
Ager	advanced glycosylation end product-specific receptor	0.012
C77370	expressed sequence C77370	0.012
Oprm1	opioid receptor, mu 1	0.012
Sox4	SRY-box containing gene 4	0.012
Mybpc3	myosin binding protein C, cardiac	0.012
Tbxa2r	thromboxane A2 receptor	0.012
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.011
Ihh	Indian hedgehog	0.011
Pkdcc	protein kinase domain containing, cytoplasmic	0.011
Cdx2	caudal type homeobox 2	0.011
Fndc7	fibronectin type III domain containing 7	0.011
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.011
Npnt	nephronectin	0.011
Nkd1	naked cuticle 1 homolog (Drosophila)	0.011
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.011
Runx2	runt related transcription factor 2	0.011
Eng	endoglin	0.011
Hoxa4	homeobox A4	0.011
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.011
Fzd8	frizzled homolog 8 (Drosophila)	0.011
Rara	retinoic acid receptor, alpha	0.011
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.011
Npr1	natriuretic peptide receptor 1	0.011
Edil3	EGF-like repeats and discoidin I-like domains 3	0.011
Esrrb	estrogen related receptor, beta	0.010
Tgfa	transforming growth factor alpha	0.010
Hif1a	hypoxia inducible factor 1, alpha subunit	0.010
Mylk2	myosin, light polypeptide kinase 2, skeletal muscle	0.010
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.010
Efna1	ephrin A1	0.010
Asb10	ankyrin repeat and SOCS box-containing 10	0.010
Drd2	dopamine receptor D2	0.010