IMP

Process View

Mus musculus

1 genes annotated in mouse

negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis

GO:2000162

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Fgfr2	fibroblast growth factor receptor 2	1.000
Ctnnb1	catenin (cadherin associated protein), beta 1	0.992
Fgfr1	fibroblast growth factor receptor 1	0.989
Bmp4	bone morphogenetic protein 4	0.987
Gli3	GLI-Kruppel family member GLI3	0.968
Shh	sonic hedgehog	0.965
Tbx3	T-box 3	0.882
Apoe	apolipoprotein E	0.868
Smo	smoothened homolog (Drosophila)	0.858
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.844
Pkd1	polycystic kidney disease 1 homolog	0.831
Vangl2	vang-like 2 (van gogh, Drosophila)	0.820
Fgfr3	fibroblast growth factor receptor 3	0.801
Gsk3b	glycogen synthase kinase 3 beta	0.755
Axin1	axin 1	0.698
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.695
Lrp6	low density lipoprotein receptor-related protein 6	0.645
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.571
Npc1	Niemann Pick type C1	0.561
Foxc1	forkhead box C1	0.504
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.460
Bmp7	bone morphogenetic protein 7	0.454
Ldlr	low density lipoprotein receptor	0.445
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.426
Zeb1	zinc finger E-box binding homeobox 1	0.391
Psen1	presenilin 1	0.333
Msx1	homeobox, msh-like 1	0.320
Foxc2	forkhead box C2	0.298
Runx2	runt related transcription factor 2	0.293
Otx2	orthodenticle homolog 2 (Drosophila)	0.286
Apc	adenomatosis polyposis coli	0.265
Sertad2	SERTA domain containing 2	0.247
Prrx1	paired related homeobox 1	0.239
Ptch1	patched homolog 1	0.221
Pparg	peroxisome proliferator activated receptor gamma	0.217
Pick1	protein interacting with C kinase 1	0.209
Pitx2	paired-like homeodomain transcription factor 2	0.206
Pax3	paired box gene 3	0.204
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.170
Mks1	Meckel syndrome, type 1	0.160
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.141
Sox11	SRY-box containing gene 11	0.135
Eya1	eyes absent 1 homolog (Drosophila)	0.134
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.134
Tgfb2	transforming growth factor, beta 2	0.131
Pbx1	pre B-cell leukemia transcription factor 1	0.129
Smad6	MAD homolog 6 (Drosophila)	0.125
Fgf8	fibroblast growth factor 8	0.120
Col1a1	collagen, type I, alpha 1	0.115
Msx2	homeobox, msh-like 2	0.106
Foxg1	forkhead box G1	0.105
Jag1	jagged 1	0.100
Egfr	epidermal growth factor receptor	0.092
Pofut1	protein O-fucosyltransferase 1	0.088
Gli2	GLI-Kruppel family member GLI2	0.086
Lrp5	low density lipoprotein receptor-related protein 5	0.086	Mouse
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.082
Hes1	hairy and enhancer of split 1 (Drosophila)	0.080
Rarg	retinoic acid receptor, gamma	0.080
Klf15	Kruppel-like factor 15	0.080
Lef1	lymphoid enhancer binding factor 1	0.078
Prrx2	paired related homeobox 2	0.075
Bmp2	bone morphogenetic protein 2	0.074
Crtc3	CREB regulated transcription coactivator 3	0.070
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.070
Sox9	SRY-box containing gene 9	0.069
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.069
T	brachyury	0.065
Cav1	caveolin 1, caveolae protein	0.064
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.062
Foxa2	forkhead box A2	0.061
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.060
Agtr2	angiotensin II receptor, type 2	0.060
Nos3	nitric oxide synthase 3, endothelial cell	0.059
Itga3	integrin alpha 3	0.056
Folr1	folate receptor 1 (adult)	0.055
Wnt5a	wingless-related MMTV integration site 5A	0.055
Ece1	endothelin converting enzyme 1	0.053
Bmp5	bone morphogenetic protein 5	0.050
App	amyloid beta (A4) precursor protein	0.050
Tenc1	tensin like C1 domain-containing phosphatase	0.049
Fgfrl1	fibroblast growth factor receptor-like 1	0.047
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.046
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.045
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.045
Tcfap2a	transcription factor AP-2, alpha	0.044
Notch2	Notch gene homolog 2 (Drosophila)	0.044
Cldn6	claudin 6	0.043
Mesdc2	mesoderm development candidate 2	0.043
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.042
Rxra	retinoid X receptor alpha	0.040
Lrp4	low density lipoprotein receptor-related protein 4	0.040	Mouse
Pax2	paired box gene 2	0.040
Wls	wntless homolog (Drosophila)	0.040
Sox2	SRY-box containing gene 2	0.039
Epas1	endothelial PAS domain protein 1	0.039
Vegfa	vascular endothelial growth factor A	0.039
Ltbr	lymphotoxin B receptor	0.039
Rara	retinoic acid receptor, alpha	0.037
Gas1	growth arrest specific 1	0.035
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.035
Rarb	retinoic acid receptor, beta	0.035
Bmp1	bone morphogenetic protein 1	0.035
Lpin1	lipin 1	0.034
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.034
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.034
Gpc3	glypican 3	0.033
Chd7	chromodomain helicase DNA binding protein 7	0.033
Hand1	heart and neural crest derivatives expressed transcript 1	0.033
Ltbp4	latent transforming growth factor beta binding protein 4	0.032
Anpep	alanyl (membrane) aminopeptidase	0.032
Ift88	intraflagellar transport 88 homolog (Chlamydomonas)	0.031
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.031
Mertk	c-mer proto-oncogene tyrosine kinase	0.031
Fn1	fibronectin 1	0.031
Gbx2	gastrulation brain homeobox 2	0.030
Igfbp4	insulin-like growth factor binding protein 4	0.030
Npr2	natriuretic peptide receptor 2	0.030
Ptprf	protein tyrosine phosphatase, receptor type, F	0.030
Gpx3	glutathione peroxidase 3	0.029
Igf1r	insulin-like growth factor I receptor	0.028
Apaf1	apoptotic peptidase activating factor 1	0.027
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.027
Dlx5	distal-less homeobox 5	0.027
Glg1	golgi apparatus protein 1	0.026
Itgb5	integrin beta 5	0.025
Tnks1bp1	tankyrase 1 binding protein 1	0.025
Lepr	leptin receptor	0.025
Smagp	small cell adhesion glycoprotein	0.025
Chrd	chordin	0.025
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.025
Acvr1	activin A receptor, type 1	0.025
Col4a3	collagen, type IV, alpha 3	0.024
Pten	phosphatase and tensin homolog	0.024
Efnb1	ephrin B1	0.024
Sall4	sal-like 4 (Drosophila)	0.022
Hoxa1	homeobox A1	0.022
Rdh10	retinol dehydrogenase 10 (all-trans)	0.022
Irf6	interferon regulatory factor 6	0.022
Slc4a2	solute carrier family 4 (anion exchanger), member 2	0.021
Ctnnd1	catenin (cadherin associated protein), delta 1	0.020
Fam20c	family with sequence similarity 20, member C	0.020
Jup	junction plakoglobin	0.020
Ghr	growth hormone receptor	0.020
Lbp	lipopolysaccharide binding protein	0.019
Hoxa5	homeobox A5	0.019
Meox2	mesenchyme homeobox 2	0.017
Trp63	transformation related protein 63	0.017
Ptk7	PTK7 protein tyrosine kinase 7	0.017
Mn1	meningioma 1	0.017
Pkdcc	protein kinase domain containing, cytoplasmic	0.017
Grb7	growth factor receptor bound protein 7	0.017
Sox13	SRY-box containing gene 13	0.016
Thra	thyroid hormone receptor alpha	0.016
Nab2	Ngfi-A binding protein 2	0.016
Tbx2	T-box 2	0.016
Pak4	p21 protein (Cdc42/Rac)-activated kinase 4	0.015
Tmem150a	transmembrane protein 150A	0.015
Crebbp	CREB binding protein	0.015
Smad3	MAD homolog 3 (Drosophila)	0.015
Col4a4	collagen, type IV, alpha 4	0.015
Ncoa3	nuclear receptor coactivator 3	0.015
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.015
Zfhx3	zinc finger homeobox 3	0.015
Yap1	yes-associated protein 1	0.015
Nodal	nodal	0.014
Otx1	orthodenticle homolog 1 (Drosophila)	0.014
Efnb2	ephrin B2	0.014
Wnt3a	wingless-related MMTV integration site 3A	0.014
Esr1	estrogen receptor 1 (alpha)	0.014
Vdr	vitamin D receptor	0.014
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.014
Pltp	phospholipid transfer protein	0.013
Alx1	ALX homeobox 1	0.013
Sorbs3	sorbin and SH3 domain containing 3	0.013
Lrp2	low density lipoprotein receptor-related protein 2	0.013	Mouse
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.013
Ephb4	Eph receptor B4	0.013
Zic3	zinc finger protein of the cerebellum 3	0.013
Notch1	Notch gene homolog 1 (Drosophila)	0.013
Ext1	exostoses (multiple) 1	0.013
Mmp2	matrix metallopeptidase 2	0.013
Gja1	gap junction protein, alpha 1	0.013
Tbx1	T-box 1	0.013
Ptms	parathymosin	0.012
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.012
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.012
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.012
Cdh1	cadherin 1	0.012
Cldn3	claudin 3	0.012
Emx2	empty spiracles homolog 2 (Drosophila)	0.011
Slc6a20b	solute carrier family 6 (neurotransmitter transporter), member 20B	0.011
Htt	huntingtin	0.011
Lep	leptin	0.011
Sntg2	syntrophin, gamma 2	0.011
Arsa	arylsulfatase A	0.011
Wwc1	WW, C2 and coiled-coil domain containing 1	0.011
Dhrs3	dehydrogenase/reductase (SDR family) member 3	0.010
Il6st	interleukin 6 signal transducer	0.010
Ppap2b	phosphatidic acid phosphatase type 2B	0.010
Ctsr	cathepsin R	0.010
Itga8	integrin alpha 8	0.010
Rnf111	ring finger 111	0.010
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.010
Sox4	SRY-box containing gene 4	0.010
Gpx1	glutathione peroxidase 1	0.010
Lima1	LIM domain and actin binding 1	0.010
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.010
Dag1	dystroglycan 1	0.010
Ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.010
Col18a1	collagen, type XVIII, alpha 1	0.010