IMP
Process View
signal transduction involved in cell cycle checkpoint
A signal transduction process that contributes to a cell cycle checkpoint.
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Click on a gene's description to view its network relationships with genes known to be involved in "signal transduction involved in cell cycle checkpoint"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Trp53 | transformation related protein 53 | 1.000 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.982 | Human | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.848 | Human | |
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.798 | ||
| Rb1 | retinoblastoma 1 | 0.740 | ||
| Brca2 | breast cancer 2 | 0.674 | ||
| Daxx | Fas death domain-associated protein | 0.594 | ||
| Pten | phosphatase and tensin homolog | 0.436 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.383 | ||
| Cdkn2a | cyclin-dependent kinase inhibitor 2A | 0.246 | ||
| Skil | SKI-like | 0.239 | ||
| Meox2 | mesenchyme homeobox 2 | 0.209 | ||
| Apc | adenomatosis polyposis coli | 0.205 | ||
| Runx1 | runt related transcription factor 1 | 0.127 | ||
| Nf1 | neurofibromatosis 1 | 0.127 | ||
| Sfn | stratifin | 0.124 | ||
| Sox4 | SRY-box containing gene 4 | 0.108 | Human | |
| Cdk4 | cyclin-dependent kinase 4 | 0.095 | ||
| Braf | Braf transforming gene | 0.090 | ||
| Rara | retinoic acid receptor, alpha | 0.090 | ||
| Kit | kit oncogene | 0.072 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.071 | ||
| Mybl2 | myeloblastosis oncogene-like 2 | 0.066 | ||
| Brca1 | breast cancer 1 | 0.065 | ||
| Thbs1 | thrombospondin 1 | 0.060 | ||
| Ikbkap | inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein | 0.058 | ||
| E2f1 | E2F transcription factor 1 | 0.057 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.056 | ||
| Cdkn2c | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.053 | ||
| Rnf8 | ring finger protein 8 | 0.049 | ||
| Tcf3 | transcription factor 3 | 0.049 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.049 | ||
| Hhat | hedgehog acyltransferase | 0.049 | ||
| Trp73 | transformation related protein 73 | 0.048 | Mouse | |
| Ccnd1 | cyclin D1 | 0.044 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.043 | ||
| Hipk1 | homeodomain interacting protein kinase 1 | 0.041 | ||
| Smn1 | survival motor neuron 1 | 0.035 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.032 | ||
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.032 | ||
| Rbl1 | retinoblastoma-like 1 (p107) | 0.029 | ||
| Trp63 | transformation related protein 63 | 0.028 | Mouse | |
| Parp1 | poly (ADP-ribose) polymerase family, member 1 | 0.028 | ||
| Gadd45a | growth arrest and DNA-damage-inducible 45 alpha | 0.028 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.027 | ||
| Wrn | Werner syndrome homolog (human) | 0.027 | ||
| Tsc1 | tuberous sclerosis 1 | 0.027 | ||
| Ppp1ca | protein phosphatase 1, catalytic subunit, alpha isoform | 0.026 | ||
| Ifrd2 | interferon-related developmental regulator 2 | 0.025 | ||
| Gtf2h3 | general transcription factor IIH, polypeptide 3 | 0.024 | ||
| Yap1 | yes-associated protein 1 | 0.024 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.024 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.024 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.024 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.023 | ||
| Xpa | xeroderma pigmentosum, complementation group A | 0.023 | ||
| Tnf | tumor necrosis factor | 0.023 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.023 | ||
| Nbn | nibrin | 0.023 | ||
| Cbx5 | chromobox homolog 5 (Drosophila HP1a) | 0.022 | ||
| Bax | BCL2-associated X protein | 0.022 | ||
| Psen1 | presenilin 1 | 0.022 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.022 | ||
| Ahr | aryl-hydrocarbon receptor | 0.022 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.022 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.021 | ||
| Rcc2 | regulator of chromosome condensation 2 | 0.021 | ||
| Nf2 | neurofibromatosis 2 | 0.021 | ||
| Mta2 | metastasis-associated gene family, member 2 | 0.020 | ||
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.020 | ||
| Dok1 | docking protein 1 | 0.020 | ||
| Srsf9 | serine/arginine-rich splicing factor 9 | 0.020 | ||
| Ddx41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.020 | ||
| Cdx2 | caudal type homeobox 2 | 0.020 | ||
| Fadd | Fas (TNFRSF6)-associated via death domain | 0.020 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.019 | ||
| Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.019 | ||
| Ret | ret proto-oncogene | 0.019 | ||
| Fzr1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.018 | ||
| Nfya | nuclear transcription factor-Y alpha | 0.018 | ||
| Cnot6 | CCR4-NOT transcription complex, subunit 6 | 0.017 | ||
| Gata3 | GATA binding protein 3 | 0.017 | ||
| Elf3 | E74-like factor 3 | 0.017 | ||
| Prmt1 | protein arginine N-methyltransferase 1 | 0.017 | ||
| Mlh1 | mutL homolog 1 (E. coli) | 0.017 | ||
| Poglut1 | protein O-glucosyltransferase 1 | 0.017 | ||
| Cldn7 | claudin 7 | 0.016 | ||
| Telo2 | TEL2, telomere maintenance 2, homolog (S. cerevisiae) | 0.016 | ||
| Rnf38 | ring finger protein 38 | 0.016 | ||
| Stk11 | serine/threonine kinase 11 | 0.016 | ||
| Cxcr4 | chemokine (C-X-C motif) receptor 4 | 0.016 | ||
| Pms2 | postmeiotic segregation increased 2 (S. cerevisiae) | 0.016 | ||
| Fam60a | family with sequence similarity 60, member A | 0.016 | ||
| Foxp3 | forkhead box P3 | 0.016 | ||
| Prps2 | phosphoribosyl pyrophosphate synthetase 2 | 0.016 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.016 | ||
| Pkp3 | plakophilin 3 | 0.015 | ||
| Men1 | multiple endocrine neoplasia 1 | 0.015 | ||
| Elp3 | elongation protein 3 homolog (S. cerevisiae) | 0.015 | ||
| Cdk6 | cyclin-dependent kinase 6 | 0.014 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.014 | ||
| Snrpb | small nuclear ribonucleoprotein B | 0.014 | ||
| Trpc2 | transient receptor potential cation channel, subfamily C, member 2 | 0.014 | ||
| Irf6 | interferon regulatory factor 6 | 0.014 | ||
| Smad5 | MAD homolog 5 (Drosophila) | 0.014 | ||
| Asxl1 | additional sex combs like 1 (Drosophila) | 0.014 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.014 | ||
| Rab25 | RAB25, member RAS oncogene family | 0.014 | ||
| Myc | myelocytomatosis oncogene | 0.014 | ||
| Rxra | retinoid X receptor alpha | 0.013 | ||
| Ints7 | integrator complex subunit 7 | 0.013 | ||
| Ruvbl2 | RuvB-like protein 2 | 0.013 | ||
| Cpne1 | copine I | 0.013 | ||
| Ptk7 | PTK7 protein tyrosine kinase 7 | 0.013 | ||
| Ntf3 | neurotrophin 3 | 0.013 | ||
| Hr | hairless | 0.013 | ||
| Terf1 | telomeric repeat binding factor 1 | 0.013 | ||
| Vav2 | vav 2 oncogene | 0.013 | ||
| Casp3 | caspase 3 | 0.012 | ||
| Cdk2 | cyclin-dependent kinase 2 | 0.012 | ||
| Lmnb1 | lamin B1 | 0.012 | ||
| Armc10 | armadillo repeat containing 10 | 0.012 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.012 | ||
| Cenpm | centromere protein M | 0.012 | ||
| Gpx2 | glutathione peroxidase 2 | 0.012 | ||
| Sytl1 | synaptotagmin-like 1 | 0.012 | ||
| Pfn1 | profilin 1 | 0.012 | ||
| Lfng | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.012 | ||
| Ap1m2 | adaptor protein complex AP-1, mu 2 subunit | 0.012 | ||
| Lsm2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.011 | ||
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 0.011 | ||
| Zfp865 | zinc finger protein 865 | 0.011 | ||
| Fam64a | family with sequence similarity 64, member A | 0.011 | ||
| Pknox1 | Pbx/knotted 1 homeobox | 0.011 | ||
| Fcgbp | Fc fragment of IgG binding protein | 0.011 | ||
| Anapc1 | anaphase promoting complex subunit 1 | 0.011 | ||
| Cxcr2 | chemokine (C-X-C motif) receptor 2 | 0.011 | ||
| Dsc3 | desmocollin 3 | 0.011 | ||
| Eif4b | eukaryotic translation initiation factor 4B | 0.011 | ||
| H2afx | H2A histone family, member X | 0.011 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.011 | ||
| Mcm8 | minichromosome maintenance deficient 8 (S. cerevisiae) | 0.011 | ||
| Cables1 | CDK5 and Abl enzyme substrate 1 | 0.011 | ||
| Tcfap4 | transcription factor AP4 | 0.011 | ||
| Ccdc114 | coiled-coil domain containing 114 | 0.011 | ||
| Krt14 | keratin 14 | 0.011 | ||
| Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.011 | ||
| Ilf3 | interleukin enhancer binding factor 3 | 0.011 | ||
| Numa1 | nuclear mitotic apparatus protein 1 | 0.011 | ||
| Mbd3 | methyl-CpG binding domain protein 3 | 0.011 | ||
| Ccnd3 | cyclin D3 | 0.011 | ||
| Dnajb13 | DnaJ (Hsp40) related, subfamily B, member 13 | 0.011 | ||
| Zfp292 | zinc finger protein 292 | 0.011 | ||
| Foxo1 | forkhead box O1 | 0.011 | ||
| Psmb2 | proteasome (prosome, macropain) subunit, beta type 2 | 0.011 | ||
| Helb | helicase (DNA) B | 0.011 | ||
| Map4k1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.011 | ||
| Nhej1 | nonhomologous end-joining factor 1 | 0.011 | ||
| Nap1l4 | nucleosome assembly protein 1-like 4 | 0.011 | ||
| Plxna3 | plexin A3 | 0.011 | ||
| Swap70 | SWA-70 protein | 0.011 | ||
| Casp2 | caspase 2 | 0.010 | Human | |
| Hcfc1 | host cell factor C1 | 0.010 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.010 | ||
| Gna15 | guanine nucleotide binding protein, alpha 15 | 0.010 | ||
| Zfp740 | zinc finger protein 740 | 0.010 | ||
| Spice1 | spindle and centriole associated protein 1 | 0.010 | ||
| Suv420h2 | suppressor of variegation 4-20 homolog 2 (Drosophila) | 0.010 | ||
| Slc39a4 | solute carrier family 39 (zinc transporter), member 4 | 0.010 | ||
| Cldn4 | claudin 4 | 0.010 | ||
| Zbtb32 | zinc finger and BTB domain containing 32 | 0.010 | ||
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.010 | ||
| Tacstd2 | tumor-associated calcium signal transducer 2 | 0.010 | ||
| Ctsw | cathepsin W | 0.010 | ||
| St14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.010 | ||
| Zfp275 | zinc finger protein 275 | 0.010 | ||
| Cbl | Casitas B-lineage lymphoma | 0.010 | ||
| Eif2s3x | eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked | 0.010 |