IMP

Process View

Mus musculus

8 genes annotated in mouse

transcription initiation from rna polymerase ii promoter

Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "transcription initiation from rna polymerase ii promoter"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "transcription initiation from rna polymerase ii promoter" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.943
Psmc3	proteasome (prosome, macropain) 26S subunit, ATPase 3	0.627	Yeast
Hand1	heart and neural crest derivatives expressed transcript 1	0.602
Hand2	heart and neural crest derivatives expressed transcript 2	0.518
Psmd4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.496
Fgf8	fibroblast growth factor 8	0.435
Gli2	GLI-Kruppel family member GLI2	0.430
Gata4	GATA binding protein 4	0.317
Pax8	paired box gene 8	0.271
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.258
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.246
Tcf3	transcription factor 3	0.207	Mouse
Wnt3a	wingless-related MMTV integration site 3A	0.194	Mouse
Vax1	ventral anterior homeobox containing gene 1	0.177
Sox9	SRY-box containing gene 9	0.169
Ikzf1	IKAROS family zinc finger 1	0.151
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.142
Tbx1	T-box 1	0.129
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.116
Foxc1	forkhead box C1	0.116
T	brachyury	0.106
Psmb6	proteasome (prosome, macropain) subunit, beta type 6	0.100
Foxc2	forkhead box C2	0.098
Rarb	retinoic acid receptor, beta	0.091
Stat2	signal transducer and activator of transcription 2	0.085
Nkx6-1	NK6 homeobox 1	0.078
Hoxd3	homeobox D3	0.076
Cd19	CD19 antigen	0.072
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.070
Tal1	T-cell acute lymphocytic leukemia 1	0.070
Pax2	paired box gene 2	0.070
Uba7	ubiquitin-like modifier activating enzyme 7	0.062
Tbx5	T-box 5	0.062
Tbp	TATA box binding protein	0.061
Hoxd13	homeobox D13	0.059
Rxra	retinoid X receptor alpha	0.058
Rarg	retinoic acid receptor, gamma	0.057
Pitx2	paired-like homeodomain transcription factor 2	0.057
Bmp7	bone morphogenetic protein 7	0.056
Isg15	ISG15 ubiquitin-like modifier	0.054
Socs1	suppressor of cytokine signaling 1	0.053
Gdnf	glial cell line derived neurotrophic factor	0.053
Lhx3	LIM homeobox protein 3	0.053
Wnt4	wingless-related MMTV integration site 4	0.052	Mouse
Gata5	GATA binding protein 5	0.050
Tbcb	tubulin folding cofactor B	0.050
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.049
Insm1	insulinoma-associated 1	0.049
En1	engrailed 1	0.047
Pou5f1	POU domain, class 5, transcription factor 1	0.047
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.046
Hoxa4	homeobox A4	0.046
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.046
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.045
Barx1	BarH-like homeobox 1	0.045
Barx2	BarH-like homeobox 2	0.045
Mesp1	mesoderm posterior 1	0.044
Lhx1	LIM homeobox protein 1	0.044
Trp63	transformation related protein 63	0.044
Ncoa6	nuclear receptor coactivator 6	0.043
Pax1	paired box gene 1	0.042
Lef1	lymphoid enhancer binding factor 1	0.042
Tgfb2	transforming growth factor, beta 2	0.041
Hmx3	H6 homeobox 3	0.041
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.041
Pou3f3	POU domain, class 3, transcription factor 3	0.041
Ctnnb1	catenin (cadherin associated protein), beta 1	0.040
Stat1	signal transducer and activator of transcription 1	0.039
Srebf2	sterol regulatory element binding factor 2	0.039
Foxn1	forkhead box N1	0.039
Gli3	GLI-Kruppel family member GLI3	0.039
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.039
Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.038	Yeast
Tbx3	T-box 3	0.037
Gli1	GLI-Kruppel family member GLI1	0.037
Hoxa13	homeobox A13	0.037
Cct7	chaperonin containing Tcp1, subunit 7 (eta)	0.036
Foxe1	forkhead box E1	0.036
Sfpi1	SFFV proviral integration 1	0.035
Psma2	proteasome (prosome, macropain) subunit, alpha type 2	0.034
Ntf3	neurotrophin 3	0.034
Fgf15	fibroblast growth factor 15	0.034
Rnf2	ring finger protein 2	0.034
Tbx2	T-box 2	0.034
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.033
Wnt1	wingless-related MMTV integration site 1	0.033	Mouse
Gata6	GATA binding protein 6	0.031
Nkx3-2	NK3 homeobox 2	0.031	Mouse
Pdx1	pancreatic and duodenal homeobox 1	0.031
Ccz1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	0.030
Wnt2b	wingless related MMTV integration site 2b	0.030	Mouse
Fgf3	fibroblast growth factor 3	0.030
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.030
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.029	Mouse
Trp53	transformation related protein 53	0.029
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.029
Rara	retinoic acid receptor, alpha	0.028
Hoxd1	homeobox D1	0.028
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.028
Psmb7	proteasome (prosome, macropain) subunit, beta type 7	0.027
Scn5a	sodium channel, voltage-gated, type V, alpha	0.027
Rpa1	replication protein A1	0.027
Cdc73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.027
Emx2	empty spiracles homolog 2 (Drosophila)	0.027
Wnt6	wingless-related MMTV integration site 6	0.026	Mouse
Stag1	stromal antigen 1	0.026
Tcf4	transcription factor 4	0.026
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.026
Adra2b	adrenergic receptor, alpha 2b	0.026
Zfpm2	zinc finger protein, multitype 2	0.026
Scaf11	SR-related CTD-associated factor 11	0.025
Amh	anti-Mullerian hormone	0.025
Med28	mediator of RNA polymerase II transcription, subunit 28 homolog (yeast)	0.025
Hoxa2	homeobox A2	0.025
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.024
Msx1	homeobox, msh-like 1	0.024
Pitx3	paired-like homeodomain transcription factor 3	0.024
Col22a1	collagen, type XXII, alpha 1	0.023
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.023
Nog	noggin	0.023
Bud31	BUD31 homolog (yeast)	0.023
Efna4	ephrin A4	0.023
Foxd2	forkhead box D2	0.023
Sall3	sal-like 3 (Drosophila)	0.022
Irf8	interferon regulatory factor 8	0.022
Pax9	paired box gene 9	0.022
Psmd6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.022
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.022
Btbd17	BTB (POZ) domain containing 17	0.022
Nfya	nuclear transcription factor-Y alpha	0.021
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.021
Alx3	aristaless-like homeobox 3	0.021
Neurog1	neurogenin 1	0.021
Pou3f1	POU domain, class 3, transcription factor 1	0.021
Pax5	paired box gene 5	0.021
Id2	inhibitor of DNA binding 2	0.020
Efna2	ephrin A2	0.020
Esrrb	estrogen related receptor, beta	0.020
Fgfr2	fibroblast growth factor receptor 2	0.020
Irgm2	immunity-related GTPase family M member 2	0.019
Tapbp	TAP binding protein	0.019
Col2a1	collagen, type II, alpha 1	0.019
Psmd13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.019
Lmx1b	LIM homeobox transcription factor 1 beta	0.019
Dlx5	distal-less homeobox 5	0.019
Fzd8	frizzled homolog 8 (Drosophila)	0.019
Cdx1	caudal type homeobox 1	0.019
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.018
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.018
Ltb	lymphotoxin B	0.018
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.018	Human
Aicda	activation-induced cytidine deaminase	0.018
Hoxb6	homeobox B6	0.018
Pten	phosphatase and tensin homolog	0.018
Wnt10b	wingless related MMTV integration site 10b	0.018
Pcm1	pericentriolar material 1	0.018
Igh	immunoglobulin heavy chain complex	0.018
Sox3	SRY-box containing gene 3	0.018
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.018
Gja5	gap junction protein, alpha 5	0.018
Sim2	single-minded homolog 2 (Drosophila)	0.018
Psma6	proteasome (prosome, macropain) subunit, alpha type 6	0.018
Gata1	GATA binding protein 1	0.017
Usp18	ubiquitin specific peptidase 18	0.017
Baz1b	bromodomain adjacent to zinc finger domain, 1B	0.017
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.017
Hoxa3	homeobox A3	0.017
Pknox1	Pbx/knotted 1 homeobox	0.017
Zic2	zinc finger protein of the cerebellum 2	0.017
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.017
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.017
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.017
Pthlh	parathyroid hormone-like peptide	0.017
Foxp3	forkhead box P3	0.016
Zfp771	zinc finger protein 771	0.016
Fgf18	fibroblast growth factor 18	0.016
Irf4	interferon regulatory factor 4	0.016	Mouse
Idua	iduronidase, alpha-L-	0.016
Igtp	interferon gamma induced GTPase	0.016
Lhx5	LIM homeobox protein 5	0.015
Pomp	proteasome maturation protein	0.015
Npas1	neuronal PAS domain protein 1	0.015
Hmx1	H6 homeobox 1	0.015
Fgf17	fibroblast growth factor 17	0.015
Cdx2	caudal type homeobox 2	0.015
Lmx1a	LIM homeobox transcription factor 1 alpha	0.015
Hcfc1	host cell factor C1	0.014
Stat6	signal transducer and activator of transcription 6	0.014
Aimp1	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	0.014
Irf7	interferon regulatory factor 7	0.014	Mouse
Sall4	sal-like 4 (Drosophila)	0.014
Padi3	peptidyl arginine deiminase, type III	0.014
Hoxb3	homeobox B3	0.014
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.014
Otx2	orthodenticle homolog 2 (Drosophila)	0.014
Ap1g1	adaptor protein complex AP-1, gamma 1 subunit	0.014
Psmd14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	0.014
Wnt7a	wingless-related MMTV integration site 7A	0.014	Mouse
Srrt	serrate RNA effector molecule homolog (Arabidopsis)	0.013
Acvr1	activin A receptor, type 1	0.013
Efnb2	ephrin B2	0.013
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.013
Traf6	TNF receptor-associated factor 6	0.013
Sox1	SRY-box containing gene 1	0.013
Trim30a	tripartite motif-containing 30A	0.013
Pou2f2	POU domain, class 2, transcription factor 2	0.013
Arl6ip4	ADP-ribosylation factor-like 6 interacting protein 4	0.013
Pitx1	paired-like homeodomain transcription factor 1	0.013
Tcf15	transcription factor 15	0.013
Zic1	zinc finger protein of the cerebellum 1	0.013
Esr1	estrogen receptor 1 (alpha)	0.013
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.013
Fbrs	fibrosin	0.013
Hoxd11	homeobox D11	0.012
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.012
Psmc5	protease (prosome, macropain) 26S subunit, ATPase 5	0.012	Yeast
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.012
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.012
Trim21	tripartite motif-containing 21	0.012
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.012
Ghr	growth hormone receptor	0.012
Fgf5	fibroblast growth factor 5	0.012
Pml	promyelocytic leukemia	0.012
Epha1	Eph receptor A1	0.012
Nup85	nucleoporin 85	0.012
Psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.012
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.012
Fgf10	fibroblast growth factor 10	0.012
Smo	smoothened homolog (Drosophila)	0.012
Tlx3	T-cell leukemia, homeobox 3	0.012
Prkcd	protein kinase C, delta	0.012
Emid2	EMI domain containing 2	0.012
Irx4	Iroquois related homeobox 4 (Drosophila)	0.012
Hoxc8	homeobox C8	0.011
Hnf1a	HNF1 homeobox A	0.011	Human
Foxf2	forkhead box F2	0.011
Cops5	COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)	0.011
Bik	BCL2-interacting killer	0.011
Sh3pxd2a	SH3 and PX domains 2A	0.011
Fgfr1	fibroblast growth factor receptor 1	0.011
Irf5	interferon regulatory factor 5	0.011	Mouse
Otp	orthopedia homolog (Drosophila)	0.011
Irs1	insulin receptor substrate 1	0.011
Tnf	tumor necrosis factor	0.011
Psmb5	proteasome (prosome, macropain) subunit, beta type 5	0.011
Fgf4	fibroblast growth factor 4	0.011
Zeb1	zinc finger E-box binding homeobox 1	0.011
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.011
Bcl3	B-cell leukemia/lymphoma 3	0.011
Prop1	paired like homeodomain factor 1	0.011
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.011
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.011
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.011
Pou3f2	POU domain, class 3, transcription factor 2	0.011
Gja3	gap junction protein, alpha 3	0.011
Ube2i	ubiquitin-conjugating enzyme E2I	0.010
Kl	klotho	0.010
Creb1	cAMP responsive element binding protein 1	0.010	Rat
Tcfap2c	transcription factor AP-2, gamma	0.010
Gipc3	GIPC PDZ domain containing family, member 3	0.010
Pax3	paired box gene 3	0.010
Eif4ebp2	eukaryotic translation initiation factor 4E binding protein 2	0.010
Tlx2	T-cell leukemia, homeobox 2	0.010
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.010