IMP

Process View

Mus musculus

2 genes annotated in mouse

nephrogenic mesenchyme morphogenesis

The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nephrogenic mesenchyme morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nephrogenic mesenchyme morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Smad4	MAD homolog 4 (Drosophila)	1.000
Smad3	MAD homolog 3 (Drosophila)	0.999	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.999
Apc	adenomatosis polyposis coli	0.999
Bmp4	bone morphogenetic protein 4	0.998
Fgfr2	fibroblast growth factor receptor 2	0.987
Axin1	axin 1	0.979
Shh	sonic hedgehog	0.977
Foxc1	forkhead box C1	0.973
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.968
Gli3	GLI-Kruppel family member GLI3	0.966
Erbb2ip	Erbb2 interacting protein	0.938
Bmp7	bone morphogenetic protein 7	0.935
Smo	smoothened homolog (Drosophila)	0.934
Otx2	orthodenticle homolog 2 (Drosophila)	0.933
Smad1	MAD homolog 1 (Drosophila)	0.922	Mouse
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.913
Ptch1	patched homolog 1	0.912
Fgfr3	fibroblast growth factor receptor 3	0.899
Gata4	GATA binding protein 4	0.886
Msx1	homeobox, msh-like 1	0.800
Smad2	MAD homolog 2 (Drosophila)	0.791	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.789
Prrx2	paired related homeobox 2	0.781
Hand1	heart and neural crest derivatives expressed transcript 1	0.761
Sox9	SRY-box containing gene 9	0.729
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.706
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.691
Lrp6	low density lipoprotein receptor-related protein 6	0.685
Foxh1	forkhead box H1	0.590
Pitx2	paired-like homeodomain transcription factor 2	0.589
Hand2	heart and neural crest derivatives expressed transcript 2	0.588
Fgf8	fibroblast growth factor 8	0.587
Bmp2	bone morphogenetic protein 2	0.547
Nodal	nodal	0.546	Mouse
Dlx5	distal-less homeobox 5	0.534
Smad6	MAD homolog 6 (Drosophila)	0.519	Mouse
Gdf5	growth differentiation factor 5	0.502	Mouse
Gdf6	growth differentiation factor 6	0.464	Mouse
Gli2	GLI-Kruppel family member GLI2	0.461
Rnf111	ring finger 111	0.456
Nog	noggin	0.429
Prrx1	paired related homeobox 1	0.400
Gsk3b	glycogen synthase kinase 3 beta	0.381
Pbx1	pre B-cell leukemia transcription factor 1	0.358
Foxc2	forkhead box C2	0.357
Hoxd13	homeobox D13	0.347
Msx2	homeobox, msh-like 2	0.346
Bptf	bromodomain PHD finger transcription factor	0.343
Tbx3	T-box 3	0.340
Tgfb2	transforming growth factor, beta 2	0.338
Acvr1	activin A receptor, type 1	0.329
Meox2	mesenchyme homeobox 2	0.327
Hoxa13	homeobox A13	0.302
Prkg1	protein kinase, cGMP-dependent, type I	0.296
Gas1	growth arrest specific 1	0.273
Zeb1	zinc finger E-box binding homeobox 1	0.265
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.254
Rarg	retinoic acid receptor, gamma	0.250
Gdf1	growth differentiation factor 1	0.235
Bmp5	bone morphogenetic protein 5	0.205	Mouse
Smurf1	SMAD specific E3 ubiquitin protein ligase 1	0.193
Smad7	MAD homolog 7 (Drosophila)	0.192	Mouse
Tbx1	T-box 1	0.191
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.188
Amhr2	anti-Mullerian hormone type 2 receptor	0.187
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.185
Pax2	paired box gene 2	0.183
Gata6	GATA binding protein 6	0.183
Zic3	zinc finger protein of the cerebellum 3	0.181
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.175
Lhx1	LIM homeobox protein 1	0.171
Gsc	goosecoid homeobox	0.166
Tdgf1	teratocarcinoma-derived growth factor 1	0.164
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.153
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.146
Rarb	retinoic acid receptor, beta	0.130
Gpc3	glypican 3	0.104
Tbx15	T-box 15	0.098
Eya1	eyes absent 1 homolog (Drosophila)	0.096
Htt	huntingtin	0.096
Fzd7	frizzled homolog 7 (Drosophila)	0.088
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.085
Tbx2	T-box 2	0.084
Bmper	BMP-binding endothelial regulator	0.082
Lef1	lymphoid enhancer binding factor 1	0.079
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.076
Chrd	chordin	0.075
Alx4	aristaless-like homeobox 4	0.074
Ptgs2	prostaglandin-endoperoxide synthase 2	0.072
Runx2	runt related transcription factor 2	0.071
Eif4enif1	eukaryotic translation initiation factor 4E nuclear import factor 1	0.070
Pknox1	Pbx/knotted 1 homeobox	0.070
Acvr1b	activin A receptor, type 1B	0.069
Hes1	hairy and enhancer of split 1 (Drosophila)	0.066
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.064
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.064
Stk11	serine/threonine kinase 11	0.063
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.061
Ybx2	Y box protein 2	0.061
Foxf1a	forkhead box F1a	0.057
Tgfbr3	transforming growth factor, beta receptor III	0.057
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.057
Axin2	axin2	0.055
Wnt3a	wingless-related MMTV integration site 3A	0.054
Tgfbr2	transforming growth factor, beta receptor II	0.053
Foxa2	forkhead box A2	0.051
Gata5	GATA binding protein 5	0.051
Esr2	estrogen receptor 2 (beta)	0.049
She	src homology 2 domain-containing transforming protein E	0.049
Alx1	ALX homeobox 1	0.046
Wnt5a	wingless-related MMTV integration site 5A	0.046
Zfp362	zinc finger protein 362	0.046
Fzd8	frizzled homolog 8 (Drosophila)	0.043
Vhl	von Hippel-Lindau tumor suppressor	0.043
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.043
Lrp5	low density lipoprotein receptor-related protein 5	0.042
Hhex	hematopoietically expressed homeobox	0.042
Ppap2b	phosphatidic acid phosphatase type 2B	0.041
Acvr2a	activin receptor IIA	0.041
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.041
Efna4	ephrin A4	0.041
Hoxb3	homeobox B3	0.040
Ptk2	PTK2 protein tyrosine kinase 2	0.040
Adra2b	adrenergic receptor, alpha 2b	0.039
Ihh	Indian hedgehog	0.039
Sox17	SRY-box containing gene 17	0.039
Bach1	BTB and CNC homology 1	0.038
Gdf3	growth differentiation factor 3	0.037
Myod1	myogenic differentiation 1	0.036
Fut1	fucosyltransferase 1	0.035
Il6st	interleukin 6 signal transducer	0.034
Gli1	GLI-Kruppel family member GLI1	0.034
Hoxd11	homeobox D11	0.032
Rhox6	reproductive homeobox 6	0.031
Wnt3	wingless-related MMTV integration site 3	0.031
Rxra	retinoid X receptor alpha	0.030
Wnt6	wingless-related MMTV integration site 6	0.030
Fgfrl1	fibroblast growth factor receptor-like 1	0.030
Mn1	meningioma 1	0.030
Jun	Jun oncogene	0.030
Hoxa11	homeobox A11	0.030
Lrp2	low density lipoprotein receptor-related protein 2	0.029
Tcf21	transcription factor 21	0.029
Tead2	TEA domain family member 2	0.028
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.027
Zfp503	zinc finger protein 503	0.027
Podxl	podocalyxin-like	0.026
Hivep1	human immunodeficiency virus type I enhancer binding protein 1	0.026
Hoxb6	homeobox B6	0.026
Itga8	integrin alpha 8	0.026
Angpt1	angiopoietin 1	0.026
Sox18	SRY-box containing gene 18	0.025
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.025
Chuk	conserved helix-loop-helix ubiquitous kinase	0.025
Gja1	gap junction protein, alpha 1	0.024
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.024
Esr1	estrogen receptor 1 (alpha)	0.024
Sox7	SRY-box containing gene 7	0.024
Irs1	insulin receptor substrate 1	0.024
Wnt4	wingless-related MMTV integration site 4	0.024
Itga3	integrin alpha 3	0.024
Cldn6	claudin 6	0.023
Cnga3	cyclic nucleotide gated channel alpha 3	0.023
Yap1	yes-associated protein 1	0.023
Pten	phosphatase and tensin homolog	0.023
Trp63	transformation related protein 63	0.023
Col13a1	collagen, type XIII, alpha 1	0.022
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.022
Rdh10	retinol dehydrogenase 10 (all-trans)	0.022
Tmprss2	transmembrane protease, serine 2	0.022
Zmym2	zinc finger, MYM-type 2	0.022
Arid1a	AT rich interactive domain 1A (SWI-like)	0.021
Crebbp	CREB binding protein	0.021
Wnt11	wingless-related MMTV integration site 11	0.021
Npnt	nephronectin	0.021
Otx1	orthodenticle homolog 1 (Drosophila)	0.021
Wnt5b	wingless-related MMTV integration site 5B	0.021
Klf3	Kruppel-like factor 3 (basic)	0.021
Epas1	endothelial PAS domain protein 1	0.021
Pthlh	parathyroid hormone-like peptide	0.021
Tead3	TEA domain family member 3	0.021
Fmn1	formin 1	0.020
Tcfap2a	transcription factor AP-2, alpha	0.020
Col2a1	collagen, type II, alpha 1	0.020
Hoxa2	homeobox A2	0.019
Vdr	vitamin D receptor	0.019
Eomes	eomesodermin homolog (Xenopus laevis)	0.019
Hoxd9	homeobox D9	0.019
Kif3a	kinesin family member 3A	0.019
Ski	ski sarcoma viral oncogene homolog (avian)	0.018
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.018
Nos3	nitric oxide synthase 3, endothelial cell	0.018
Efnb1	ephrin B1	0.018
Rara	retinoic acid receptor, alpha	0.018
Col9a2	collagen, type IX, alpha 2	0.018
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.018
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.018
Cilp2	cartilage intermediate layer protein 2	0.018
Rnf44	ring finger protein 44	0.018
Fzd1	frizzled homolog 1 (Drosophila)	0.018
Klf10	Kruppel-like factor 10	0.018
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.017
Rab5b	RAB5B, member RAS oncogene family	0.017
Barx1	BarH-like homeobox 1	0.017
Wt1	Wilms tumor 1 homolog	0.017
Npr2	natriuretic peptide receptor 2	0.017
Gtf2i	general transcription factor II I	0.016
Foxf2	forkhead box F2	0.016
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.016
Kit	kit oncogene	0.016
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.016
Fgf15	fibroblast growth factor 15	0.016
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.016
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.016
Pkdcc	protein kinase domain containing, cytoplasmic	0.016
Cfc1	cripto, FRL-1, cryptic family 1	0.015
Bmp6	bone morphogenetic protein 6	0.015	Mouse
Mks1	Meckel syndrome, type 1	0.015
Vangl2	vang-like 2 (van gogh, Drosophila)	0.015
Atr	ataxia telangiectasia and Rad3 related	0.015
Fabp9	fatty acid binding protein 9, testis	0.015
Mecom	MDS1 and EVI1 complex locus	0.015
Megf8	multiple EGF-like-domains 8	0.015
Gip	gastric inhibitory polypeptide	0.014
Cldn3	claudin 3	0.014
Tdh	L-threonine dehydrogenase	0.014
Prop1	paired like homeodomain factor 1	0.014
Art5	ADP-ribosyltransferase 5	0.014
Sall4	sal-like 4 (Drosophila)	0.014
Wwc2	WW, C2 and coiled-coil domain containing 2	0.014
Fgf18	fibroblast growth factor 18	0.014
Tbx4	T-box 4	0.013
Pnliprp2	pancreatic lipase-related protein 2	0.013
Pgap1	post-GPI attachment to proteins 1	0.013
Acvr2b	activin receptor IIB	0.013
Cyp2s1	cytochrome P450, family 2, subfamily s, polypeptide 1	0.013
Gdf9	growth differentiation factor 9	0.013
Lefty1	left right determination factor 1	0.013
Lmx1b	LIM homeobox transcription factor 1 beta	0.013
Il13	interleukin 13	0.013
Ctf1	cardiotrophin 1	0.013
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.013
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.013
Tcfap2c	transcription factor AP-2, gamma	0.013
Phlda2	pleckstrin homology-like domain, family A, member 2	0.013
Fuz	fuzzy homolog (Drosophila)	0.013
Ank	progressive ankylosis	0.013
Gm4980	predicted gene 4980	0.013
Tcf15	transcription factor 15	0.013
Hoxa9	homeobox A9	0.013
T	brachyury	0.013
Rac1	RAS-related C3 botulinum substrate 1	0.012
Gata2	GATA binding protein 2	0.012
Fzd6	frizzled homolog 6 (Drosophila)	0.012
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.012
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.012
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.012
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.012
Emid2	EMI domain containing 2	0.012
Adam17	a disintegrin and metallopeptidase domain 17	0.012
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.012
Csnk1e	casein kinase 1, epsilon	0.012
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.012
Pax3	paired box gene 3	0.012
Otp	orthopedia homolog (Drosophila)	0.012
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.011
Lrp4	low density lipoprotein receptor-related protein 4	0.011
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.011
Padi3	peptidyl arginine deiminase, type III	0.011
Nf1	neurofibromatosis 1	0.011
Kank2	KN motif and ankyrin repeat domains 2	0.011
Krt72-ps	keratin 72, pseudogene	0.011
Tert	telomerase reverse transcriptase	0.011
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.011
Ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.011
Lama1	laminin, alpha 1	0.011
Pofut1	protein O-fucosyltransferase 1	0.011
Sycn	syncollin	0.011
Fzd4	frizzled homolog 4 (Drosophila)	0.011
Emx2	empty spiracles homolog 2 (Drosophila)	0.011
Mylk	myosin, light polypeptide kinase	0.011
Emp2	epithelial membrane protein 2	0.011
Fut7	fucosyltransferase 7	0.011
Npr3	natriuretic peptide receptor 3	0.011
Fgfr4	fibroblast growth factor receptor 4	0.010
Hoxa10	homeobox A10	0.010
Vezf1	vascular endothelial zinc finger 1	0.010
Foxp1	forkhead box P1	0.010
Tcl1	T-cell lymphoma breakpoint 1	0.010
Efna1	ephrin A1	0.010
Ar	androgen receptor	0.010
Mapk12	mitogen-activated protein kinase 12	0.010
Hnf1b	HNF1 homeobox B	0.010
S1pr3	sphingosine-1-phosphate receptor 3	0.010
Myh11	myosin, heavy polypeptide 11, smooth muscle	0.010
Tecta	tectorin alpha	0.010
Mafa	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)	0.010
Kitl	kit ligand	0.010
Ctnna1	catenin (cadherin associated protein), alpha 1	0.010