IMP

Process View

Mus musculus

3 genes annotated in mouse

Multi-species View

regulation of glutamate secretion

GO:0014048

Any process that modulates the frequency, rate or extent of the controlled release of glutamate.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of glutamate secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of glutamate secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	1.000
Dlg4	discs, large homolog 4 (Drosophila)	0.841
Drd2	dopamine receptor D2	0.597
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.524
Grm1	glutamate receptor, metabotropic 1	0.258
Nf1	neurofibromatosis 1	0.184
Crhr1	corticotropin releasing hormone receptor 1	0.169
Epas1	endothelial PAS domain protein 1	0.132
Gabbr2	gamma-aminobutyric acid (GABA) B receptor, 2	0.128
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.118
Clock	circadian locomotor output cycles kaput	0.111
Irak4	interleukin-1 receptor-associated kinase 4	0.108
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.106
Plcb1	phospholipase C, beta 1	0.102
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.099
Nos1	nitric oxide synthase 1, neuronal	0.087
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.082
Nos3	nitric oxide synthase 3, endothelial cell	0.081
Plcg1	phospholipase C, gamma 1	0.077
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.077
Emx1	empty spiracles homolog 1 (Drosophila)	0.077
Jph3	junctophilin 3	0.075
Ptgir	prostaglandin I receptor (IP)	0.068
Prkcc	protein kinase C, gamma	0.065
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.063
Inpp5j	inositol polyphosphate 5-phosphatase J	0.054
Wnt2b	wingless related MMTV integration site 2b	0.054
Cnr1	cannabinoid receptor 1 (brain)	0.052
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.052
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.051
Sstr2	somatostatin receptor 2	0.050
Syn2	synapsin II	0.050
Calb2	calbindin 2	0.049
Vip	vasoactive intestinal polypeptide	0.049
Atxn1	ataxin 1	0.048
App	amyloid beta (A4) precursor protein	0.048
Adam17	a disintegrin and metallopeptidase domain 17	0.045
Lin7b	lin-7 homolog B (C. elegans)	0.044
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.044
Crmp1	collapsin response mediator protein 1	0.044
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.043
Adora2a	adenosine A2a receptor	0.043	Rat
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.042
Aatk	apoptosis-associated tyrosine kinase	0.042
Cx3cr1	chemokine (C-X3-C) receptor 1	0.041
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.040
Cit	citron	0.038
Dnajb8	DnaJ (Hsp40) homolog, subfamily B, member 8	0.038
Slc12a5	solute carrier family 12, member 5	0.038
Ache	acetylcholinesterase	0.038
Adam23	a disintegrin and metallopeptidase domain 23	0.037
Ar	androgen receptor	0.036
Vav2	vav 2 oncogene	0.036
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.036
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.034
Apc2	adenomatosis polyposis coli 2	0.034
Dbh	dopamine beta hydroxylase	0.033
St8sia5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	0.033
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.033
Plp1	proteolipid protein (myelin) 1	0.033
Inpp4a	inositol polyphosphate-4-phosphatase, type I	0.032
Syt1	synaptotagmin I	0.032
Epb4.9	erythrocyte protein band 4.9	0.032
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.032
Apoe	apolipoprotein E	0.032
Apln	apelin	0.031
Rtn4r	reticulon 4 receptor	0.031
Cel	carboxyl ester lipase	0.031
Vstm2l	V-set and transmembrane domain containing 2-like	0.031
Hif1a	hypoxia inducible factor 1, alpha subunit	0.030
Sox10	SRY-box containing gene 10	0.030
Npy2r	neuropeptide Y receptor Y2	0.029
Socs5	suppressor of cytokine signaling 5	0.029
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.029
Tac2	tachykinin 2	0.028
Cplx1	complexin 1	0.028
Ncoa1	nuclear receptor coactivator 1	0.028
Syt2	synaptotagmin II	0.028
Ank1	ankyrin 1, erythroid	0.027
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.027
Sntb1	syntrophin, basic 1	0.027
Xcr1	chemokine (C motif) receptor 1	0.027
Nt5e	5' nucleotidase, ecto	0.026
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.026
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.025
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.025
Th	tyrosine hydroxylase	0.025
Tspo2	translocator protein 2	0.025
Shank2	SH3/ankyrin domain gene 2	0.025
Hba-a2	hemoglobin alpha, adult chain 2	0.024
Dlg2	discs, large homolog 2 (Drosophila)	0.024
Slc23a2	solute carrier family 23 (nucleobase transporters), member 2	0.024
Thrb	thyroid hormone receptor beta	0.024
Gcgr	glucagon receptor	0.024
Abcb9	ATP-binding cassette, sub-family B (MDR/TAP), member 9	0.024
Sorcs3	sortilin-related VPS10 domain containing receptor 3	0.024
2310002J15Rik	RIKEN cDNA 2310002J15 gene	0.024
Rit2	Ras-like without CAAX 2	0.024
Dpysl2	dihydropyrimidinase-like 2	0.023	Rat
Figla	folliculogenesis specific basic helix-loop-helix	0.023
Ldb2	LIM domain binding 2	0.023
Syt5	synaptotagmin V	0.023
Shank1	SH3/ankyrin domain gene 1	0.023
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.023
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.023
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.023
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.023
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.022
a	nonagouti	0.022
Diras1	DIRAS family, GTP-binding RAS-like 1	0.022
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.022
Accn1	amiloride-sensitive cation channel 1, neuronal (degenerin)	0.022
Dmd	dystrophin, muscular dystrophy	0.021
Ucn	urocortin	0.021
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.021
Lrfn1	leucine rich repeat and fibronectin type III domain containing 1	0.021
Dync1i1	dynein cytoplasmic 1 intermediate chain 1	0.021
Neurod2	neurogenic differentiation 2	0.021
Slc30a3	solute carrier family 30 (zinc transporter), member 3	0.021
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.021
Prkce	protein kinase C, epsilon	0.021
Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	0.021
Sult4a1	sulfotransferase family 4A, member 1	0.020
Plxna1	plexin A1	0.020
Pcdh12	protocadherin 12	0.020
Arc	activity regulated cytoskeletal-associated protein	0.020
Snap25	synaptosomal-associated protein 25	0.020
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.020
Cplx3	complexin 3	0.019
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.019
Efna3	ephrin A3	0.019
Oxt	oxytocin	0.019
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.019
Rasgrp2	RAS, guanyl releasing protein 2	0.019
Tlx2	T-cell leukemia, homeobox 2	0.018
Cxcl2	chemokine (C-X-C motif) ligand 2	0.018
Pklr	pyruvate kinase liver and red blood cell	0.018
Krt6a	keratin 6A	0.018
Cntn4	contactin 4	0.018
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.018
Gata1	GATA binding protein 1	0.018
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.018
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.018
Col25a1	collagen, type XXV, alpha 1	0.017
Gpr162	G protein-coupled receptor 162	0.017
Cldn26	claudin 26	0.017
Camk4	calcium/calmodulin-dependent protein kinase IV	0.017
Vmn1r65	vomeronasal 1 receptor 65	0.017
Chi3l1	chitinase 3-like 1	0.017
Abcg8	ATP-binding cassette, sub-family G (WHITE), member 8	0.017
Ntsr2	neurotensin receptor 2	0.017
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.017
Gypa	glycophorin A	0.017
Egfr	epidermal growth factor receptor	0.017
Vhl	von Hippel-Lindau tumor suppressor	0.017
Gpr3	G-protein coupled receptor 3	0.017
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.017	Rat
Stat3	signal transducer and activator of transcription 3	0.017
Tpo	thyroid peroxidase	0.017
Mc5r	melanocortin 5 receptor	0.017
Ghr	growth hormone receptor	0.017
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.017
Tmed8	transmembrane emp24 domain containing 8	0.016
Itm2b	integral membrane protein 2B	0.016
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.016
Tbxa2r	thromboxane A2 receptor	0.016
Dpp7	dipeptidylpeptidase 7	0.016
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.016
Sstr5	somatostatin receptor 5	0.016
Shc3	src homology 2 domain-containing transforming protein C3	0.016
Ldb3	LIM domain binding 3	0.016
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.016
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.016
Mag	myelin-associated glycoprotein	0.016
Tacr1	tachykinin receptor 1	0.016
Chga	chromogranin A	0.015
Ptafr	platelet-activating factor receptor	0.015
Krtap10-4	keratin associated protein 10-4	0.015
Selp	selectin, platelet	0.015
Gnrh1	gonadotropin releasing hormone 1	0.015
Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.015
Krt32	keratin 32	0.015
Rbfox3	RNA binding protein, fox-1 homolog (C. elegans) 3	0.015
Tgfbr1	transforming growth factor, beta receptor I	0.015
Sstr4	somatostatin receptor 4	0.015
Apba1	amyloid beta (A4) precursor protein binding, family A, member 1	0.015
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.015
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.015
2410066E13Rik	RIKEN cDNA 2410066E13 gene	0.015
Rph3a	rabphilin 3A	0.015
Ppyr1	pancreatic polypeptide receptor 1	0.015
Pcx	pyruvate carboxylase	0.015
Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	0.015
S1pr3	sphingosine-1-phosphate receptor 3	0.015
Pparg	peroxisome proliferator activated receptor gamma	0.015
4930404N11Rik	RIKEN cDNA 4930404N11 gene	0.015
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.015
Npy	neuropeptide Y	0.014
Il13	interleukin 13	0.014
Prnp	prion protein	0.014
Htr6	5-hydroxytryptamine (serotonin) receptor 6	0.014
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.014
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.014
Pten	phosphatase and tensin homolog	0.014
1810065E05Rik	RIKEN cDNA 1810065E05 gene	0.014
Cacna2d2	calcium channel, voltage-dependent, alpha 2/delta subunit 2	0.014
Sst	somatostatin	0.014
Cntnap1	contactin associated protein-like 1	0.014
Dpp6	dipeptidylpeptidase 6	0.014
Phf1	PHD finger protein 1	0.014
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.014
F7	coagulation factor VII	0.014
Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.014
Grm2	glutamate receptor, metabotropic 2	0.014
Grin2c	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	0.014
Ccl17	chemokine (C-C motif) ligand 17	0.014
Chst3	carbohydrate (chondroitin 6/keratan) sulfotransferase 3	0.014
Stom	stomatin	0.014
Adam11	a disintegrin and metallopeptidase domain 11	0.014
Ribc2	RIB43A domain with coiled-coils 2	0.014
Qsox1	quiescin Q6 sulfhydryl oxidase 1	0.014
Ccrl2	chemokine (C-C motif) receptor-like 2	0.014
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.013
Trpm2	transient receptor potential cation channel, subfamily M, member 2	0.013
Cry2	cryptochrome 2 (photolyase-like)	0.013
Ngp	neutrophilic granule protein	0.013
Mt3	metallothionein 3	0.013
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.013
Fut7	fucosyltransferase 7	0.013
Baiap3	BAI1-associated protein 3	0.013
Usf2	upstream transcription factor 2	0.013
Gjc2	gap junction protein, gamma 2	0.013
Galr3	galanin receptor 3	0.013
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.013
Fxyd7	FXYD domain-containing ion transport regulator 7	0.013
Shisa9	shisa homolog 9 (Xenopus laevis)	0.013
Acvrl1	activin A receptor, type II-like 1	0.013
Lepr	leptin receptor	0.013
S100a5	S100 calcium binding protein A5	0.013
Aph1b	anterior pharynx defective 1b homolog (C. elegans)	0.013
Fam151a	family with sequence simliarity 151, member A	0.013
Timp4	tissue inhibitor of metalloproteinase 4	0.013
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.012
Stx1b	syntaxin 1B	0.012
3110047P20Rik	RIKEN cDNA 3110047P20 gene	0.012
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.012
Prrt1	proline-rich transmembrane protein 1	0.012
Chrm3	cholinergic receptor, muscarinic 3, cardiac	0.012
Dlgap3	discs, large (Drosophila) homolog-associated protein 3	0.012
Spry4	sprouty homolog 4 (Drosophila)	0.012
Tcte1	t-complex-associated testis expressed 1	0.012
Vav3	vav 3 oncogene	0.012
S1pr1	sphingosine-1-phosphate receptor 1	0.012
Fbxo41	F-box protein 41	0.012
Pax4	paired box gene 4	0.012
Pla2g2e	phospholipase A2, group IIE	0.012
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.012
Hcn2	hyperpolarization-activated, cyclic nucleotide-gated K+ 2	0.012
Sdc3	syndecan 3	0.012
Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	0.012
C1ql1	complement component 1, q subcomponent-like 1	0.012
Nefl	neurofilament, light polypeptide	0.012
Ip6k1	inositol hexaphosphate kinase 1	0.012
Nhedc2	Na+/H+ exchanger domain containing 2	0.012
Accn4	amiloride-sensitive cation channel 4, pituitary	0.012
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.012
Amh	anti-Mullerian hormone	0.012
Scrt1	scratch homolog 1, zinc finger protein (Drosophila)	0.012
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.012
Il1b	interleukin 1 beta	0.012
Insr	insulin receptor	0.012
Rnf112	ring finger protein 112	0.012
Cort	cortistatin	0.012
Tgfbr3	transforming growth factor, beta receptor III	0.012
Trpm5	transient receptor potential cation channel, subfamily M, member 5	0.012
Arhgdig	Rho GDP dissociation inhibitor (GDI) gamma	0.012
Faim2	Fas apoptotic inhibitory molecule 2	0.012
Gja5	gap junction protein, alpha 5	0.012
Dmrtc1a	DMRT-like family C1a	0.012
Arf2	ADP-ribosylation factor 2	0.011
Mmd2	monocyte to macrophage differentiation-associated 2	0.011
A530016L24Rik	RIKEN cDNA A530016L24 gene	0.011
Cd38	CD38 antigen	0.011
Tbxas1	thromboxane A synthase 1, platelet	0.011
Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B	0.011
Gm13275	predicted gene 13275	0.011
Elk1	ELK1, member of ETS oncogene family	0.011
Adam22	a disintegrin and metallopeptidase domain 22	0.011
Abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.011
Mchr1	melanin-concentrating hormone receptor 1	0.011
Wdr78	WD repeat domain 78	0.011
Hrk	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.011
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.011
Lrrk2	leucine-rich repeat kinase 2	0.011
Epor	erythropoietin receptor	0.011
Gab2	growth factor receptor bound protein 2-associated protein 2	0.011
Arnt	aryl hydrocarbon receptor nuclear translocator	0.011
Srcin1	SRC kinase signaling inhibitor 1	0.011
Gna15	guanine nucleotide binding protein, alpha 15	0.011
Rasgrp1	RAS guanyl releasing protein 1	0.011
Vamp2	vesicle-associated membrane protein 2	0.011
Ins2	insulin II	0.011
Epha10	Eph receptor A10	0.011
Ifna1	interferon alpha 1	0.011
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.011
Has1	hyaluronan synthase1	0.011
Homer1	homer homolog 1 (Drosophila)	0.011
Il10rb	interleukin 10 receptor, beta	0.011
Hrh2	histamine receptor H2	0.011
Pigz	phosphatidylinositol glycan anchor biosynthesis, class Z	0.011
Rusc1	RUN and SH3 domain containing 1	0.011
Oprl1	opioid receptor-like 1	0.011
Fgf13	fibroblast growth factor 13	0.011
Braf	Braf transforming gene	0.011
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.011
Xiap	X-linked inhibitor of apoptosis	0.011
Egln3	EGL nine homolog 3 (C. elegans)	0.011
Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	0.011
Gpr27	G protein-coupled receptor 27	0.011
Ctsz	cathepsin Z	0.011
Clps	colipase, pancreatic	0.011
Cmtm5	CKLF-like MARVEL transmembrane domain containing 5	0.011
Pomc	pro-opiomelanocortin-alpha	0.011
Pdzk1ip1	PDZK1 interacting protein 1	0.011
Idua	iduronidase, alpha-L-	0.011
Ppp6r2	protein phosphatase 6, regulatory subunit 2	0.011
Rgs4	regulator of G-protein signaling 4	0.011
Actl7b	actin-like 7b	0.011
Ids	iduronate 2-sulfatase	0.011
Olfr71	olfactory receptor 71	0.011
Gpr33	G protein-coupled receptor 33	0.011
Rap2b	RAP2B, member of RAS oncogene family	0.011
Dsg1a	desmoglein 1 alpha	0.011
Oxtr	oxytocin receptor	0.011
Ctrb1	chymotrypsinogen B1	0.011
Spert	spermatid associated	0.011
Car7	carbonic anhydrase 7	0.011
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.011
Rasal1	RAS protein activator like 1 (GAP1 like)	0.011
Scg3	secretogranin III	0.010
Aplp2	amyloid beta (A4) precursor-like protein 2	0.010
Plau	plasminogen activator, urokinase	0.010
Irf5	interferon regulatory factor 5	0.010
Bcan	brevican	0.010
Mtap2	microtubule-associated protein 2	0.010
Gal	galanin	0.010
Pvrl1	poliovirus receptor-related 1	0.010
Siae	sialic acid acetylesterase	0.010
Nrip3	nuclear receptor interacting protein 3	0.010
Crtac1	cartilage acidic protein 1	0.010
Tnfrsf23	tumor necrosis factor receptor superfamily, member 23	0.010
Il12a	interleukin 12a	0.010
9130404H23Rik	RIKEN cDNA 9130404H23 gene	0.010
Prima1	proline rich membrane anchor 1	0.010
Tdrd1	tudor domain containing 1	0.010
Krtap5-1	keratin associated protein 5-1	0.010
Cryaa	crystallin, alpha A	0.010
Gpr26	G protein-coupled receptor 26	0.010
Rasgrf1	RAS protein-specific guanine nucleotide-releasing factor 1	0.010
Necab3	N-terminal EF-hand calcium binding protein 3	0.010
F5	coagulation factor V	0.010
Folr2	folate receptor 2 (fetal)	0.010
Stk32c	serine/threonine kinase 32C	0.010
Sprr1a	small proline-rich protein 1A	0.010
Klf3	Kruppel-like factor 3 (basic)	0.010
Naga	N-acetyl galactosaminidase, alpha	0.010
Sardh	sarcosine dehydrogenase	0.010
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.010
Ephx1	epoxide hydrolase 1, microsomal	0.010
Usp42	ubiquitin specific peptidase 42	0.010
Trfr2	transferrin receptor 2	0.010