IMP

Process View

Mus musculus

3 genes annotated in mouse

spindle assembly involved in female meiosis

The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "spindle assembly involved in female meiosis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "spindle assembly involved in female meiosis" (in gray)

Name	Description	Probability	Func Analog Organism
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.944	Fly
Cdk1	cyclin-dependent kinase 1	0.941
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.920
Cdca5	cell division cycle associated 5	0.869
Ccnb1	cyclin B1	0.785
Prc1	protein regulator of cytokinesis 1	0.769
Ccna2	cyclin A2	0.691
Birc5	baculoviral IAP repeat-containing 5	0.631
H2afx	H2A histone family, member X	0.540
Cdc25b	cell division cycle 25 homolog B (S. pombe)	0.522	Fly
Racgap1	Rac GTPase-activating protein 1	0.520
Ccnb2	cyclin B2	0.490
Kif22	kinesin family member 22	0.439
Aurkb	aurora kinase B	0.398
Kif4	kinesin family member 4	0.391
Cdca8	cell division cycle associated 8	0.352
Ube2c	ubiquitin-conjugating enzyme E2C	0.339
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.323
Trim59	tripartite motif-containing 59	0.315
Ccnf	cyclin F	0.289
Kif23	kinesin family member 23	0.278
Cdc25a	cell division cycle 25 homolog A (S. pombe)	0.258	Fly
Ckap2	cytoskeleton associated protein 2	0.240
Ncaph	non-SMC condensin I complex, subunit H	0.238
Kif11	kinesin family member 11	0.223
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.196
Ttk	Ttk protein kinase	0.177
Top2a	topoisomerase (DNA) II alpha	0.175
Anln	anillin, actin binding protein	0.166
Tacc3	transforming, acidic coiled-coil containing protein 3	0.163
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.151
Cdkn3	cyclin-dependent kinase inhibitor 3	0.150
Fam64a	family with sequence similarity 64, member A	0.143
Gtse1	G two S phase expressed protein 1	0.132
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.118
Mxd3	Max dimerization protein 3	0.108
Plk1	polo-like kinase 1 (Drosophila)	0.107	Fly
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.106
Plk4	polo-like kinase 4 (Drosophila)	0.105
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.104
Aspm	asp (abnormal spindle)-like, microcephaly associated (Drosophila)	0.101
Rrm2	ribonucleotide reductase M2	0.097
Spag5	sperm associated antigen 5	0.093
Incenp	inner centromere protein	0.082
Kif20a	kinesin family member 20A	0.082
Rad51ap1	RAD51 associated protein 1	0.081
Gsg2	germ cell-specific gene 2	0.080
Mis18bp1	MIS18 binding protein 1	0.079
Tcf19	transcription factor 19	0.078
Hmgb2	high mobility group box 2	0.077
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.072
Mtpn	myotrophin	0.070
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.068
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.067
Lmnb1	lamin B1	0.066
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.064
Brca1	breast cancer 1	0.063
E2f8	E2F transcription factor 8	0.058
Capza1	capping protein (actin filament) muscle Z-line, alpha 1	0.054
Dtl	denticleless homolog (Drosophila)	0.054
Ccdc99	coiled-coil domain containing 99	0.053
Smc4	structural maintenance of chromosomes 4	0.053
Tmpo	thymopoietin	0.052
Ect2	ect2 oncogene	0.051
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.050
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.050
Smc2	structural maintenance of chromosomes 2	0.050
Stil	Scl/Tal1 interrupting locus	0.047
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.045
Cenpa	centromere protein A	0.045
Lig1	ligase I, DNA, ATP-dependent	0.044
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.044
Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.044
Rasa1	RAS p21 protein activator 1	0.042
Cenpk	centromere protein K	0.041
D2Ertd750e	DNA segment, Chr 2, ERATO Doi 750, expressed	0.040
Pola1	polymerase (DNA directed), alpha 1	0.040
Hells	helicase, lymphoid specific	0.039
Smc6	structural maintenance of chromosomes 6	0.039
Cdca2	cell division cycle associated 2	0.038
Lbr	lamin B receptor	0.038
Trip13	thyroid hormone receptor interactor 13	0.038
Cdc7	cell division cycle 7 (S. cerevisiae)	0.035
Mastl	microtubule associated serine/threonine kinase-like	0.035
Cep55	centrosomal protein 55	0.035
Mki67	antigen identified by monoclonal antibody Ki 67	0.035
Pmf1	polyamine-modulated factor 1	0.034
Cdca4	cell division cycle associated 4	0.032
Rap2c	RAP2C, member of RAS oncogene family	0.032
Cenpn	centromere protein N	0.031
4930427A07Rik	RIKEN cDNA 4930427A07 gene	0.031
Iqgap3	IQ motif containing GTPase activating protein 3	0.031
Nusap1	nucleolar and spindle associated protein 1	0.030
Sae1	SUMO1 activating enzyme subunit 1	0.029
S1pr4	sphingosine-1-phosphate receptor 4	0.029
Diap3	diaphanous homolog 3 (Drosophila)	0.028
Cbx5	chromobox homolog 5 (Drosophila HP1a)	0.028
Kpna3	karyopherin (importin) alpha 3	0.028
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.027
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.026
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.026
Cdt1	chromatin licensing and DNA replication factor 1	0.026
Stag1	stromal antigen 1	0.025
2810417H13Rik	RIKEN cDNA 2810417H13 gene	0.025
Prim2	DNA primase, p58 subunit	0.025
Foxm1	forkhead box M1	0.024
Ccne1	cyclin E1	0.024
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.024
Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.023
Exo1	exonuclease 1	0.023
Cenpm	centromere protein M	0.022
Lims1	LIM and senescent cell antigen-like domains 1	0.021
Hnrpll	heterogeneous nuclear ribonucleoprotein L-like	0.021
Rcc1	regulator of chromosome condensation 1	0.020
Tk1	thymidine kinase 1	0.020
Sept2	septin 2	0.019	Mouse
Eea1	early endosome antigen 1	0.019
Mcm10	minichromosome maintenance deficient 10 (S. cerevisiae)	0.019
Mybl2	myeloblastosis oncogene-like 2	0.019
Morf4l2	mortality factor 4 like 2	0.018
Nptn	neuroplastin	0.018
Gsc	goosecoid homeobox	0.018
Adam10	a disintegrin and metallopeptidase domain 10	0.018
Blm	Bloom syndrome, RecQ helicase-like	0.018
Pbk	PDZ binding kinase	0.017
Cxcr5	chemokine (C-X-C motif) receptor 5	0.016
Melk	maternal embryonic leucine zipper kinase	0.016
Smap1	stromal membrane-associated protein 1	0.016
Ska1	spindle and kinetochore associated complex subunit 1	0.016
Mns1	meiosis-specific nuclear structural protein 1	0.016
Calm1	calmodulin 1	0.016
Sgol1	shugoshin-like 1 (S. pombe)	0.016
Rrm1	ribonucleotide reductase M1	0.016
Tpm4	tropomyosin 4	0.016
Aurka	aurora kinase A	0.016
Kif2c	kinesin family member 2C	0.015	Fly
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.015
Brca2	breast cancer 2	0.015
Gtf2a1	general transcription factor II A, 1	0.015
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.015
Rnf26	ring finger protein 26	0.015
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.015
Cenpe	centromere protein E	0.015
Whsc1	Wolf-Hirschhorn syndrome candidate 1 (human)	0.015
Mtmr6	myotubularin related protein 6	0.014
6720463M24Rik	RIKEN cDNA 6720463M24 gene	0.014
Cr2	complement receptor 2	0.014
Ckap2l	cytoskeleton associated protein 2-like	0.014
Nasp	nuclear autoantigenic sperm protein (histone-binding)	0.014
H2afz	H2A histone family, member Z	0.014
Cks1b	CDC28 protein kinase 1b	0.014	Fly
Cenpf	centromere protein F	0.014
Vps35	vacuolar protein sorting 35	0.014
Dna2	DNA replication helicase 2 homolog (yeast)	0.014
Eme1	essential meiotic endonuclease 1 homolog 1 (S. pombe)	0.014
Cdca3	cell division cycle associated 3	0.014
Haus4	HAUS augmin-like complex, subunit 4	0.013
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.013
Kpna2	karyopherin (importin) alpha 2	0.013
Orc1	origin recognition complex, subunit 1	0.013
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.013
Ccdc88a	coiled coil domain containing 88A	0.013
Mphosph9	M-phase phosphoprotein 9	0.013
Top2b	topoisomerase (DNA) II beta	0.013
Espl1	extra spindle poles-like 1 (S. cerevisiae)	0.013
Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.013
Ncapd2	non-SMC condensin I complex, subunit D2	0.013
Chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.013
Ncapg	non-SMC condensin I complex, subunit G	0.013
Cntrob	centrobin, centrosomal BRCA2 interacting protein	0.012
Trip12	thyroid hormone receptor interactor 12	0.012
Rnaseh2c	ribonuclease H2, subunit C	0.012
Fbxo30	F-box protein 30	0.012
Tfdp1	transcription factor Dp 1	0.012
Sh3bgrl	SH3-binding domain glutamic acid-rich protein like	0.012
Fam83d	family with sequence similarity 83, member D	0.012
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.012
Dync1i2	dynein cytoplasmic 1 intermediate chain 2	0.012
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.012
Blk	B lymphoid kinase	0.012
E130303B06Rik	RIKEN cDNA E130303B06 gene	0.012
Stag2	stromal antigen 2	0.012
Mapre1	microtubule-associated protein, RP/EB family, member 1	0.012
Ccdc123	coiled-coil domain containing 123	0.011
Aaas	achalasia, adrenocortical insufficiency, alacrimia	0.011
Chek2	CHK2 checkpoint homolog (S. pombe)	0.011
Qk	quaking	0.011
Pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.011
Cltc	clathrin, heavy polypeptide (Hc)	0.011
Rangap1	RAN GTPase activating protein 1	0.011
Nans	N-acetylneuraminic acid synthase (sialic acid synthase)	0.011
Haus3	HAUS augmin-like complex, subunit 3	0.011
Ckap5	cytoskeleton associated protein 5	0.011
Prim1	DNA primase, p49 subunit	0.011
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.011
Rdbp	RD RNA-binding protein	0.011
3110003A17Rik	RIKEN cDNA 3110003A17 gene	0.011
Uba6	ubiquitin-like modifier activating enzyme 6	0.011
Taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.011
Sass6	spindle assembly 6 homolog (C. elegans)	0.011
Tuba1b	tubulin, alpha 1B	0.011
Tcf12	transcription factor 12	0.010
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.010
Cks2	CDC28 protein kinase regulatory subunit 2	0.010	Fly
Rap1a	RAS-related protein-1a	0.010
Pycr2	pyrroline-5-carboxylate reductase family, member 2	0.010
Ccnc	cyclin C	0.010
E2f1	E2F transcription factor 1	0.010
Pold2	polymerase (DNA directed), delta 2, regulatory subunit	0.010
Cdk2	cyclin-dependent kinase 2	0.010
Hnrnpr	heterogeneous nuclear ribonucleoprotein R	0.010
Cdca7	cell division cycle associated 7	0.010