IMP

Process View

Mus musculus

11 genes annotated in mouse

gamma delta t cell differentiation

The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "gamma delta t cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "gamma delta t cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Notch1	Notch gene homolog 1 (Drosophila)	0.998
Fyn	Fyn proto-oncogene	0.980	Mouse
Stat5a	signal transducer and activator of transcription 5A	0.961
Cd247	CD247 antigen	0.945
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.829
Ptprc	protein tyrosine phosphatase, receptor type, C	0.816
Stat5b	signal transducer and activator of transcription 5B	0.712
Foxp3	forkhead box P3	0.694
Irf9	interferon regulatory factor 9	0.627
Inpp5d	inositol polyphosphate-5-phosphatase D	0.608
Lck	lymphocyte protein tyrosine kinase	0.600
Was	Wiskott-Aldrich syndrome homolog (human)	0.476
Il2rg	interleukin 2 receptor, gamma chain	0.464
Fas	Fas (TNF receptor superfamily member 6)	0.415
Notch2	Notch gene homolog 2 (Drosophila)	0.408
Ikzf1	IKAROS family zinc finger 1	0.361
Cd28	CD28 antigen	0.346
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.336
Psen1	presenilin 1	0.324
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.320
Cd19	CD19 antigen	0.318
Nab2	Ngfi-A binding protein 2	0.316
Lat	linker for activation of T cells	0.302
Dll1	delta-like 1 (Drosophila)	0.301	Mouse
Pten	phosphatase and tensin homolog	0.264
Lyz2	lysozyme 2	0.260
Grb2	growth factor receptor bound protein 2	0.243
Ptgs2	prostaglandin-endoperoxide synthase 2	0.231
Egr2	early growth response 2	0.222	Mouse
Cbl	Casitas B-lineage lymphoma	0.220
Zap70	zeta-chain (TCR) associated protein kinase	0.207	Mouse
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.178
Ccr6	chemokine (C-C motif) receptor 6	0.160
Itk	IL2-inducible T-cell kinase	0.153
Fos	FBJ osteosarcoma oncogene	0.148
Hcls1	hematopoietic cell specific Lyn substrate 1	0.140
Kiss1	KiSS-1 metastasis-suppressor	0.130
Ptk2	PTK2 protein tyrosine kinase 2	0.127
Efnb2	ephrin B2	0.126
Ahr	aryl-hydrocarbon receptor	0.123
Efs	embryonal Fyn-associated substrate	0.119
Tcra	T-cell receptor alpha chain	0.113
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.112
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.108
Cd22	CD22 antigen	0.101
Lepr	leptin receptor	0.099
Plcg2	phospholipase C, gamma 2	0.094
Ptpre	protein tyrosine phosphatase, receptor type, E	0.093	Mouse
Ar	androgen receptor	0.093
Vangl2	vang-like 2 (van gogh, Drosophila)	0.088
Myd88	myeloid differentiation primary response gene 88	0.085
Il6st	interleukin 6 signal transducer	0.082
Vav1	vav 1 oncogene	0.080
Trim21	tripartite motif-containing 21	0.070
Rgs14	regulator of G-protein signaling 14	0.069
Pou2af1	POU domain, class 2, associating factor 1	0.067
Fosb	FBJ osteosarcoma oncogene B	0.065
Fgfr1	fibroblast growth factor receptor 1	0.060
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.060
Junb	Jun-B oncogene	0.059
Stat3	signal transducer and activator of transcription 3	0.059	Mouse
Csf1	colony stimulating factor 1 (macrophage)	0.057
Sykb	spleen tyrosine kinase	0.054
Nab1	Ngfi-A binding protein 1	0.054
Gata3	GATA binding protein 3	0.054
Col4a3	collagen, type IV, alpha 3	0.053
Rag2	recombination activating gene 2	0.052
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.051
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.051
Ptf1a	pancreas specific transcription factor, 1a	0.051
Nckap1l	NCK associated protein 1 like	0.049
Tlr4	toll-like receptor 4	0.049
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.047
Esr1	estrogen receptor 1 (alpha)	0.045
Il2	interleukin 2	0.045
Rasal1	RAS protein activator like 1 (GAP1 like)	0.044
Dok1	docking protein 1	0.044
Ifnar2	interferon (alpha and beta) receptor 2	0.044
Cd4	CD4 antigen	0.044
Cd79b	CD79B antigen	0.042
Chd7	chromodomain helicase DNA binding protein 7	0.042
Tbx18	T-box18	0.041
Blnk	B-cell linker	0.041
Fyb	FYN binding protein	0.040
Ager	advanced glycosylation end product-specific receptor	0.040
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.039
Kit	kit oncogene	0.039
Ms4a15	membrane-spanning 4-domains, subfamily A, member 15	0.037
Zfp36	zinc finger protein 36	0.037
Jak2	Janus kinase 2	0.036
Lama5	laminin, alpha 5	0.036
Hes1	hairy and enhancer of split 1 (Drosophila)	0.035
Blk	B lymphoid kinase	0.035	Mouse
Prrt1	proline-rich transmembrane protein 1	0.034
Itgax	integrin alpha X	0.034
Mesp2	mesoderm posterior 2	0.032
Foxn1	forkhead box N1	0.032
Hoxa1	homeobox A1	0.031
Igh	immunoglobulin heavy chain complex	0.030
Egr1	early growth response 1	0.029	Mouse
S1pr4	sphingosine-1-phosphate receptor 4	0.029
Il4ra	interleukin 4 receptor, alpha	0.029
Folr4	folate receptor 4 (delta)	0.028
Cd8a	CD8 antigen, alpha chain	0.028
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.028
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.028
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.027
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.027
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.027
9430031J16Rik	RIKEN cDNA 9430031J16 gene	0.027
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.026
Neurl1a	neuralized homolog 1A (Drosophila)	0.026
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.026
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.026
Sox2	SRY-box containing gene 2	0.025
Csf1r	colony stimulating factor 1 receptor	0.025
Cd5	CD5 antigen	0.025
Sash3	SAM and SH3 domain containing 3	0.025
Atxn1	ataxin 1	0.024
Il2rb	interleukin 2 receptor, beta chain	0.024
Il27ra	interleukin 27 receptor, alpha	0.024
Ptprn	protein tyrosine phosphatase, receptor type, N	0.024
Laptm5	lysosomal-associated protein transmembrane 5	0.024
Nrarp	Notch-regulated ankyrin repeat protein	0.023
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.023
Il7r	interleukin 7 receptor	0.023
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.023
Jak1	Janus kinase 1	0.021
Il17ra	interleukin 17 receptor A	0.021
Pdcd6ip	programmed cell death 6 interacting protein	0.020
Foxo1	forkhead box O1	0.020
Wipf1	WAS/WASL interacting protein family, member 1	0.020
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.020
Itgal	integrin alpha L	0.019
Ebi3	Epstein-Barr virus induced gene 3	0.019
Sftpb	surfactant associated protein B	0.019
Dlx2	distal-less homeobox 2	0.019
Cd44	CD44 antigen	0.019
Ncoa3	nuclear receptor coactivator 3	0.019
Jun	Jun oncogene	0.018
Irf6	interferon regulatory factor 6	0.018
Fgfr2	fibroblast growth factor receptor 2	0.018
Emx2	empty spiracles homolog 2 (Drosophila)	0.017
Socs1	suppressor of cytokine signaling 1	0.017
Lcp1	lymphocyte cytosolic protein 1	0.017
Bcl2	B-cell leukemia/lymphoma 2	0.017
Hcst	hematopoietic cell signal transducer	0.017
Il1r1	interleukin 1 receptor, type I	0.017
Ier2	immediate early response 2	0.016
Adar	adenosine deaminase, RNA-specific	0.016
Src	Rous sarcoma oncogene	0.016	Mouse
Dusp1	dual specificity phosphatase 1	0.016
Il6	interleukin 6	0.016
Stx11	syntaxin 11	0.015
Lhx9	LIM homeobox protein 9	0.015
Rasa3	RAS p21 protein activator 3	0.015
Cd37	CD37 antigen	0.015
Socs3	suppressor of cytokine signaling 3	0.015
Foxg1	forkhead box G1	0.015
Ncr1	natural cytotoxicity triggering receptor 1	0.015
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.015
Pxn	paxillin	0.015
Sit1	suppression inducing transmembrane adaptor 1	0.015
Prkce	protein kinase C, epsilon	0.015
Zfhx4	zinc finger homeodomain 4	0.015
Dok2	docking protein 2	0.015
Jak3	Janus kinase 3	0.015
Dtx1	deltex 1 homolog (Drosophila)	0.014
Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	0.014
Chl1	cell adhesion molecule with homology to L1CAM	0.014
Itga6	integrin alpha 6	0.014
Ctnnb1	catenin (cadherin associated protein), beta 1	0.014
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.014
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.014
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.013
5830411N06Rik	RIKEN cDNA 5830411N06 gene	0.013
Gdnf	glial cell line derived neurotrophic factor	0.013
Ttc7	tetratricopeptide repeat domain 7	0.013
Egr3	early growth response 3	0.013
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.013
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.013
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.012
Arhgap9	Rho GTPase activating protein 9	0.012
Apc	adenomatosis polyposis coli	0.012
Sh2d1a	SH2 domain protein 1A	0.012
Ptprcap	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein	0.012
Rasgrp1	RAS guanyl releasing protein 1	0.012
Rb1	retinoblastoma 1	0.012
Diap1	diaphanous homolog 1 (Drosophila)	0.012
Reln	reelin	0.012
Pax2	paired box gene 2	0.012
Fpr1	formyl peptide receptor 1	0.012
Lhx3	LIM homeobox protein 3	0.012
Sox6	SRY-box containing gene 6	0.012	Mouse
Hoxa2	homeobox A2	0.011
Ccr7	chemokine (C-C motif) receptor 7	0.011
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.011
Eya1	eyes absent 1 homolog (Drosophila)	0.011
Irf8	interferon regulatory factor 8	0.011
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.011
Col25a1	collagen, type XXV, alpha 1	0.011
Cr2	complement receptor 2	0.011
Card11	caspase recruitment domain family, member 11	0.011
Pitx1	paired-like homeodomain transcription factor 1	0.011
Ptk7	PTK7 protein tyrosine kinase 7	0.011
Nrtn	neurturin	0.011
Col4a4	collagen, type IV, alpha 4	0.011
Btg2	B-cell translocation gene 2, anti-proliferative	0.011
Ghr	growth hormone receptor	0.011
Bcar1	breast cancer anti-estrogen resistance 1	0.011
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.011
Stat4	signal transducer and activator of transcription 4	0.010	Mouse
Hmha1	histocompatibility (minor) HA-1	0.010
Notch3	Notch gene homolog 3 (Drosophila)	0.010
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.010
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.010
Acp2	acid phosphatase 2, lysosomal	0.010
Lypd5	Ly6/Plaur domain containing 5	0.010
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.010
Drd4	dopamine receptor D4	0.010
Yes1	Yamaguchi sarcoma viral (v-yes) oncogene homolog 1	0.010	Mouse
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.010
Spna1	spectrin alpha 1	0.010
Lcp2	lymphocyte cytosolic protein 2	0.010