IMP
Process View
negative regulation of neural precursor cell proliferation
Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of neural precursor cell proliferation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Trp53 | transformation related protein 53 | 0.917 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.851 | ||
| Rb1 | retinoblastoma 1 | 0.817 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.796 | ||
| Rxra | retinoid X receptor alpha | 0.739 | ||
| Pten | phosphatase and tensin homolog | 0.737 | ||
| Shh | sonic hedgehog | 0.707 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.666 | ||
| Arid1b | AT rich interactive domain 1B (SWI-like) | 0.654 | ||
| Id1 | inhibitor of DNA binding 1 | 0.638 | Mouse | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.621 | ||
| Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.572 | Fly | |
| Id3 | inhibitor of DNA binding 3 | 0.544 | Mouse | |
| Tcf3 | transcription factor 3 | 0.541 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.474 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.444 | ||
| Egfr | epidermal growth factor receptor | 0.324 | ||
| Gata4 | GATA binding protein 4 | 0.311 | Mouse | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.309 | ||
| Sox2 | SRY-box containing gene 2 | 0.298 | ||
| Pax3 | paired box gene 3 | 0.287 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.265 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.248 | ||
| Efnb2 | ephrin B2 | 0.247 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.209 | ||
| Vegfa | vascular endothelial growth factor A | 0.207 | ||
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.206 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.175 | ||
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.174 | ||
| Grb2 | growth factor receptor bound protein 2 | 0.159 | ||
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.158 | ||
| Apc | adenomatosis polyposis coli | 0.152 | ||
| E2f1 | E2F transcription factor 1 | 0.151 | ||
| Klf3 | Kruppel-like factor 3 (basic) | 0.147 | ||
| Foxc1 | forkhead box C1 | 0.141 | ||
| Rnf2 | ring finger protein 2 | 0.139 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.135 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.133 | ||
| Fgf8 | fibroblast growth factor 8 | 0.133 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.127 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.121 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.120 | ||
| Sox4 | SRY-box containing gene 4 | 0.117 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.114 | ||
| Hoxa1 | homeobox A1 | 0.100 | ||
| Jag1 | jagged 1 | 0.099 | ||
| Ntf3 | neurotrophin 3 | 0.098 | Mouse | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.091 | ||
| Pax6 | paired box gene 6 | 0.087 | ||
| Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | 0.085 | ||
| Braf | Braf transforming gene | 0.081 | ||
| Parva | parvin, alpha | 0.076 | ||
| Myl9 | myosin, light polypeptide 9, regulatory | 0.074 | ||
| Rara | retinoic acid receptor, alpha | 0.070 | ||
| Lims1 | LIM and senescent cell antigen-like domains 1 | 0.069 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.068 | ||
| Cdkn2a | cyclin-dependent kinase inhibitor 2A | 0.068 | ||
| Kit | kit oncogene | 0.067 | ||
| Zfpm2 | zinc finger protein, multitype 2 | 0.067 | ||
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.065 | ||
| Tbx3 | T-box 3 | 0.063 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.061 | ||
| Pax2 | paired box gene 2 | 0.061 | ||
| Gata6 | GATA binding protein 6 | 0.061 | Mouse | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.058 | ||
| Ret | ret proto-oncogene | 0.057 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.055 | ||
| Hr | hairless | 0.054 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.052 | ||
| Trp63 | transformation related protein 63 | 0.052 | Mouse | |
| Ilk | integrin linked kinase | 0.051 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.049 | ||
| Smarcd1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.048 | ||
| Fos | FBJ osteosarcoma oncogene | 0.048 | ||
| Fgf10 | fibroblast growth factor 10 | 0.045 | ||
| Smarcb1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.043 | ||
| Arhgef7 | Rho guanine nucleotide exchange factor (GEF7) | 0.042 | ||
| Neurod1 | neurogenic differentiation 1 | 0.041 | ||
| Tbx1 | T-box 1 | 0.040 | ||
| Ntrk3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.039 | ||
| Ar | androgen receptor | 0.039 | ||
| Nrg1 | neuregulin 1 | 0.039 | ||
| Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 0.038 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.038 | ||
| Igbp1 | immunoglobulin (CD79A) binding protein 1 | 0.036 | ||
| Egr3 | early growth response 3 | 0.035 | ||
| Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.035 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.034 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.034 | ||
| Psen1 | presenilin 1 | 0.033 | ||
| Mesp1 | mesoderm posterior 1 | 0.033 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.032 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.031 | ||
| Tcf4 | transcription factor 4 | 0.031 | ||
| Runx1 | runt related transcription factor 1 | 0.031 | ||
| Bdnf | brain derived neurotrophic factor | 0.030 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.030 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.030 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.030 | ||
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.030 | ||
| Gfra1 | glial cell line derived neurotrophic factor family receptor alpha 1 | 0.029 | ||
| Smarcc2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.029 | Fly | |
| Foxg1 | forkhead box G1 | 0.027 | ||
| Nf2 | neurofibromatosis 2 | 0.027 | ||
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.026 | ||
| Mitf | microphthalmia-associated transcription factor | 0.025 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.025 | ||
| Flii | flightless I homolog (Drosophila) | 0.024 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.024 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.024 | ||
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.024 | ||
| Cbl | Casitas B-lineage lymphoma | 0.024 | ||
| Asxl1 | additional sex combs like 1 (Drosophila) | 0.023 | ||
| Crkl | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.023 | ||
| Gja5 | gap junction protein, alpha 5 | 0.023 | ||
| Sox9 | SRY-box containing gene 9 | 0.023 | ||
| Tcfcp2l1 | transcription factor CP2-like 1 | 0.023 | ||
| Adam19 | a disintegrin and metallopeptidase domain 19 (meltrin beta) | 0.022 | ||
| Numa1 | nuclear mitotic apparatus protein 1 | 0.022 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.022 | ||
| Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.021 | ||
| Rarg | retinoic acid receptor, gamma | 0.020 | ||
| Kitl | kit ligand | 0.020 | ||
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.020 | ||
| Phox2a | paired-like homeobox 2a | 0.020 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.020 | ||
| Trp73 | transformation related protein 73 | 0.020 | Mouse | |
| Tln1 | talin 1 | 0.020 | ||
| Vsx2 | visual system homeobox 2 | 0.020 | ||
| Numb | numb gene homolog (Drosophila) | 0.020 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.020 | ||
| 6330403K07Rik | RIKEN cDNA 6330403K07 gene | 0.019 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.019 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.019 | ||
| Sfn | stratifin | 0.019 | ||
| Meox2 | mesenchyme homeobox 2 | 0.018 | ||
| Vcl | vinculin | 0.018 | Mouse | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.018 | ||
| Spag8 | sperm associated antigen 8 | 0.018 | ||
| Gdnf | glial cell line derived neurotrophic factor | 0.018 | ||
| Chrd | chordin | 0.018 | ||
| Sox11 | SRY-box containing gene 11 | 0.017 | ||
| Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.017 | ||
| Smarcd3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | 0.017 | ||
| Lhx5 | LIM homeobox protein 5 | 0.017 | ||
| Ptf1a | pancreas specific transcription factor, 1a | 0.017 | ||
| Gja1 | gap junction protein, alpha 1 | 0.016 | ||
| a | nonagouti | 0.016 | ||
| Rarb | retinoic acid receptor, beta | 0.016 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.016 | ||
| Crx | cone-rod homeobox containing gene | 0.016 | ||
| Runx1t1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.016 | ||
| Mab21l1 | mab-21-like 1 (C. elegans) | 0.016 | ||
| Hprt | hypoxanthine guanine phosphoribosyl transferase | 0.016 | ||
| Foxf1a | forkhead box F1a | 0.016 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.015 | ||
| Vti1a | vesicle transport through interaction with t-SNAREs homolog 1A (yeast) | 0.015 | ||
| Nos2 | nitric oxide synthase 2, inducible | 0.015 | ||
| Pdlim5 | PDZ and LIM domain 5 | 0.015 | ||
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.015 | ||
| Krt19 | keratin 19 | 0.015 | ||
| Ccnd1 | cyclin D1 | 0.014 | ||
| Smo | smoothened homolog (Drosophila) | 0.014 | ||
| Shc1 | src homology 2 domain-containing transforming protein C1 | 0.014 | ||
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.014 | ||
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.014 | ||
| Ctbp2 | C-terminal binding protein 2 | 0.014 | ||
| Klf4 | Kruppel-like factor 4 (gut) | 0.014 | ||
| Tbx5 | T-box 5 | 0.014 | ||
| Tuba1a | tubulin, alpha 1A | 0.014 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.014 | ||
| Fzr1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.014 | ||
| Arhgef1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.014 | ||
| Slc38a5 | solute carrier family 38, member 5 | 0.014 | ||
| Ahr | aryl-hydrocarbon receptor | 0.014 | ||
| Gfi1b | growth factor independent 1B | 0.013 | ||
| Ep300 | E1A binding protein p300 | 0.013 | ||
| Hoxa13 | homeobox A13 | 0.013 | ||
| Cd151 | CD151 antigen | 0.013 | ||
| Creb1 | cAMP responsive element binding protein 1 | 0.013 | ||
| Bcor | BCL6 interacting corepressor | 0.013 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.013 | ||
| Foxc2 | forkhead box C2 | 0.013 | ||
| Plekhg2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.012 | ||
| Fgf3 | fibroblast growth factor 3 | 0.012 | ||
| Gnai2 | guanine nucleotide binding protein (G protein), alpha inhibiting 2 | 0.012 | ||
| Nf1 | neurofibromatosis 1 | 0.012 | ||
| Maged1 | melanoma antigen, family D, 1 | 0.012 | ||
| Foxo1 | forkhead box O1 | 0.012 | ||
| She | src homology 2 domain-containing transforming protein E | 0.012 | ||
| Gata5 | GATA binding protein 5 | 0.012 | Mouse | |
| Tax1bp3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.012 | ||
| Srsf4 | serine/arginine-rich splicing factor 4 | 0.012 | ||
| Sox10 | SRY-box containing gene 10 | 0.012 | ||
| Gab1 | growth factor receptor bound protein 2-associated protein 1 | 0.012 | ||
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.012 | ||
| Efna1 | ephrin A1 | 0.012 | ||
| Men1 | multiple endocrine neoplasia 1 | 0.012 | ||
| Tcfap2c | transcription factor AP-2, gamma | 0.012 | ||
| Yap1 | yes-associated protein 1 | 0.012 | ||
| Dcbld2 | discoidin, CUB and LCCL domain containing 2 | 0.011 | ||
| Ikbkap | inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein | 0.011 | ||
| Foxe3 | forkhead box E3 | 0.011 | ||
| Pou3f2 | POU domain, class 3, transcription factor 2 | 0.011 | ||
| Dusp1 | dual specificity phosphatase 1 | 0.011 | ||
| Msx2 | homeobox, msh-like 2 | 0.011 | ||
| Hdac1 | histone deacetylase 1 | 0.011 | ||
| Espn | espin | 0.011 | ||
| Irf6 | interferon regulatory factor 6 | 0.011 | ||
| Cdx2 | caudal type homeobox 2 | 0.011 | ||
| Mybl2 | myeloblastosis oncogene-like 2 | 0.011 | ||
| Neurog2 | neurogenin 2 | 0.011 | ||
| Ets2 | E26 avian leukemia oncogene 2, 3' domain | 0.011 | ||
| Arhgap21 | Rho GTPase activating protein 21 | 0.011 | ||
| Src | Rous sarcoma oncogene | 0.011 | ||
| Fez1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.011 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.010 | ||
| Mecp2 | methyl CpG binding protein 2 | 0.010 | ||
| Hoxb4 | homeobox B4 | 0.010 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.010 | ||
| Stat6 | signal transducer and activator of transcription 6 | 0.010 |