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Danio rerio

2 genes annotated in zebrafish

pancreatic a cell development

The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "pancreatic a cell development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "pancreatic a cell development" (in gray)

Name	Description	Probability	Func Analog Organism
isl1	islet1	1.000
nkx2.2a	NK2 transcription factor related 2a	0.999
dla	deltaA	0.995
olig2	oligodendrocyte lineage transcription factor 2	0.994
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.982
neurog1	neurogenin 1	0.974
dbx1a	developing brain homeobox 1a	0.958
barhl2	BarH-like 2	0.942
neurod	neurogenic differentiation	0.932
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.797
otx2	orthodenticle homolog 2	0.767
pax2a	paired box gene 2a	0.765
neurod4	neurogenic differentiation 4	0.709
mnx1	motor neuron and pancreas homeobox 1	0.688
prox1	prospero-related homeobox gene 1	0.664
atoh7	atonal homolog 7	0.664
elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.650
shha	sonic hedgehog a	0.618
dlb	deltaB	0.617
pax6a	paired box gene 6a	0.612	Human Mouse Rat
foxa1	forkhead box A1	0.595
otpb	orthopedia homolog b	0.592
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.571
pax6b	paired box gene 6b	0.520	Human Mouse Rat
vsx1	visual system homeobox 1 homolog, chx10-like	0.506	Zebrafish
lhx5	LIM homeobox 5	0.450	Zebrafish
gbx1	gastrulation brain homeobox 1	0.442
ins	preproinsulin	0.432
dld	deltaD	0.431
rx3	retinal homeobox gene 3	0.417
notch1a	notch homolog 1a	0.374
foxn4	forkhead box N4	0.343
lhx1a	LIM homeobox 1a	0.333	Zebrafish
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.332
gata3	GATA-binding protein 3	0.304
six3a	sine oculis homeobox homolog 3a	0.297
foxg1a	forkhead box G1a	0.275
foxa2	forkhead box A2	0.267
gbx2	gastrulation brain homeo box 2	0.258
hlxb9la	homeo box HB9 like a	0.252
mab21l2	mab-21-like 2	0.246
nkx6.1	NK6 transcription factor related, locus 1 (Drosophila)	0.242
irx3a	iroquois homeobox protein 3a	0.238
nkx2.2b	NK2 transcription factor related 2b	0.233
insm1b	insulinoma-associated 1b	0.215
isl2a	islet2a	0.207	Zebrafish
pou3f1	POU class 3 homeobox 1	0.204
evx1	even-skipped homeobox 1	0.203
olig3	oligodendrocyte transcription factor 3	0.200
gata2a	GATA-binding protein 2a	0.196
sox10	SRY-box containing gene 10	0.195
meis2.2	myeloid ecotropic viral integration site 2.2	0.193
hoxa2b	homeo box A2b	0.192
sim1a	single-minded homolog 1a (Drosophila)	0.192
vsx2	visual system homeobox 2	0.191	Zebrafish
hoxb8a	homeo box B8a	0.183
hhex	hematopoietically expressed homeobox	0.181
fezf2	FEZ family zinc finger 2	0.172
tal1	T-cell acute lymphocytic leukemia 1	0.172
otpa	orthopedia homolog a	0.166
lhx3	LIM homeobox 3	0.163
nkx2.1b	NK2 homeobox 1b	0.163
ptf1a	pancreas specific transcription factor, 1a	0.157
irx1b	iroquois homeobox protein 1, b	0.156
tbx2b	T-box 2b	0.156
ntn1b	netrin 1b	0.152
foxd3	forkhead box D3	0.151
dlx2b	distal-less homeobox gene 2b	0.146
pax4	paired box 4	0.142
meis3	myeloid ecotropic viral integration site 3	0.140
meis2.1	myeloid ecotropic viral integration site 2.1	0.137
nkx2.1a	NK2 homeobox 1a	0.135
six3b	sine oculis homeobox homolog 3b	0.134
sst1.1	somatostatin 1, tandem duplicate 1	0.132
pitx2	paired-like homeodomain transcription factor 2	0.128
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.122
mib	mind bomb	0.121
th	tyrosine hydroxylase	0.119
st8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.115
camkvb	CaM kinase-like vesicle-associated b	0.108
hhip	hedgehog interacting protein	0.103
flot1	flotillin 1	0.103
dcc	deleted in colorectal carcinoma	0.101
dlx2a	distal-less homeobox gene 2a	0.101
sox19a	SRY-box containing gene 19a	0.098
eng2b	engrailed 2b	0.095
dbx1b	developing brain homeobox 1b	0.095
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.093	Zebrafish
sst2	somatostatin 2	0.092
mab21l1	mab-21-like 1	0.091
tal2	T-cell acute lymphocytic leukemia 2	0.091
irx4a	iroquois homeobox protein 4a	0.088
hoxc8a	homeo box C8a	0.088
hbbe3	hemoglobin beta embryonic-3	0.086
eng2a	engrailed 2a	0.084
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.084
her3	hairy-related 3	0.081
otx5	orthodenticle homolog 5	0.079
scube2	signal peptide, CUB domain, EGF-like 2	0.077
sox2	SRY-box containing gene 2	0.075
gria1a	glutamate receptor, ionotropic, AMPA 1a	0.074
pou4f2	POU domain, class 4, transcription factor 2	0.074
fgf10a	fibroblast growth factor 10a	0.073
hoxc4a	homeo box C4a	0.072
prl	prolactin	0.072
coe2	coe2	0.072
slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.072
mecom	MDS1 and EVI1 complex locus	0.070
olfm2	olfactomedin 2	0.070
sox1a	SRY-box containing gene 1a	0.069
otx1b	orthodenticle homolog 1b	0.067
nkx2.3	NK2 transcription factor related 3	0.067
foxp2	forkhead box P2	0.067
ek1	eph-like kinase 1	0.066
inab	internexin neuronal intermediate filament protein, alpha b	0.066
lhx2b	LIM homeobox 2b	0.065	Zebrafish
dmbx1a	diencephalon/mesencephalon homeobox 1a	0.063
tfap2a	transcription factor AP-2 alpha	0.062
nkx1.2la	NK1 transcription factor related 2-like,a	0.060
six4b	sine oculis homeobox homolog 4b	0.058
cryaba	crystallin, alpha B, a	0.057
hoxb1a	homeo box B1a	0.056
hoxa4a	homeo box A4a	0.055
eya1	eyes absent homolog 1	0.054
dlx6a	distal-less homeobox gene 6a	0.053
hmx3	homeo box (H6 family) 3	0.053
plp1a	proteolipid protein 1a	0.052
irx7	iroquois homeobox protein 7	0.052
ptch2	patched 2	0.050
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.050
hoxb5a	homeo box B5a	0.050
oprd1b	opioid receptor, delta 1b	0.049
tbx5a	T-box 5a	0.049
zmynd11	zinc finger, MYND domain containing 11	0.046
dlx1a	distal-less homeobox gene 1a	0.044
dlc	deltaC	0.044
pou3f3b	POU class 3 homeobox 3b	0.043
hoxa9a	homeo box A9a	0.043
rad21	RAD21 homolog (S. pombe)	0.043
tlx2	T-cell leukemia, homeobox 2	0.041
jag1b	jagged 1b	0.040
gcga	glucagon a and glucagon a-like	0.040
her8a	hairy-related 8a	0.040
gata6	GATA-binding protein 6	0.039
wnt1	wingless-type MMTV integration site family, member 1	0.039
irx4b	iroquois homeobox protein 4b	0.038
bhlhe22	basic helix-loop-helix family, member e22	0.038
irx1a	iroquois homeobox protein 1, a	0.038
osr2	odd-skipped related 2 (Drosophila)	0.037
chrna6	cholinergic receptor, nicotinic, alpha 6	0.037
ihhb	Indian hedgehog homolog b	0.037
olig4	oligodendrocyte transcription factor 4	0.036
glra4a	glycine receptor, alpha 4a	0.036
suv39h1a	suppressor of variegation 3-9 homolog 1a	0.035
rx2	retinal homeobox gene 2	0.035
barhl1.2	BarH-like 1.2	0.035
nkx2.9	NK2 transcription factor related, locus 9 (Drosophila)	0.034
cdx4	caudal type homeo box transcription factor 4	0.033
tbx20	T-box 20	0.033
fev	FEV (ETS oncogene family)	0.032
tbx6	T-box gene 6	0.031
lef1	lymphocyte enhancer binding factor 1	0.031
dct	dopachrome tautomerase	0.030
phox2b	paired-like homeobox 2b	0.029
grem2	gremlin 2, cysteine knot superfamily	0.029
nxph1	neurexophilin 1	0.029
foxa3	forkhead box A3	0.029
emx3	empty spiracles homeobox 3	0.029
gfra1b	gdnf family receptor alpha 1b	0.029
nkx6.2	NK6 transcription factor related, locus 2	0.029
nanos3	nanos homolog 3	0.028
pou3f3a	POU class 3 homeobox 3a	0.028
eomesa	eomesodermin homolog a	0.028
phox2a	paired-like homeobox 2a	0.028
pcdh10b	protocadherin 10b	0.027
foxi1	forkhead box I1	0.027
mcm3l	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like	0.027
zgc:152986	zgc:152986	0.027
mitfa	microphthalmia-associated transcription factor a	0.027
eng1b	engrailed 1b	0.027
traf4a	tnf receptor-associated factor 4a	0.026
hlxb9lb	homeo box HB9 like b	0.026
cdh6	cadherin 6	0.026
hmx4	H6 family homeobox 4	0.025
irx5a	iroquois homeobox protein 5a	0.025
zgc:55574	zgc:55574	0.025
slc17a6b	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b	0.024
adcyap1r1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	0.024
syne2b	spectrin repeat containing, nuclear envelope 2b	0.024
gng3	guanine nucleotide binding protein (G protein), gamma 3	0.024
six4a	sine oculis homeobox homolog 4a	0.023
opn4a	opsin 4a (melanopsin)	0.023
zgc:162969	zgc:162969	0.023
msgn1	mesogenin 1	0.023
nos1	nitric oxide synthase 1 (neuronal)	0.023
crb2a	crumbs homolog 2a	0.022
fzd8a	frizzled homolog 8a	0.022
hoxb2a	homeo box B2a	0.022
gria3b	glutamate receptor, ionotrophic, AMPA 3b	0.022
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.021
foxb1.1	forkhead box B1.1	0.021
lmo2	LIM domain only 2 (rhombotin-like 1)	0.021
crygmxl2	crystallin, gamma MX, like 2	0.021
mpx	myeloid-specific peroxidase	0.021
has3	hyaluronan synthase 3	0.020
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.020
htr1aa	5-hydroxytryptamine (serotonin) receptor 1A a	0.020
cntn2	contactin 2	0.020
epha4b	eph receptor A4b	0.020
zic6	zic family member 6	0.020
pdx1	pancreatic and duodenal homeobox 1	0.020
sox21b	SRY-box containing gene 21 b	0.020
hnf1ba	HNF1 homeobox Ba	0.019
fzd8b	frizzled homolog 8b	0.019
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.019
her5	hairy-related 5	0.019
fgf8b	fibroblast growth factor 8 b	0.019
gata1a	GATA binding protein 1a	0.019
zgc:64141	zgc:64141	0.019
si:dkeyp-34c12.1	si:dkeyp-34c12.1	0.019
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.019
ptch1	patched 1	0.019
ntn1a	netrin 1a	0.019
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.018
fzd5	frizzled homolog 5	0.018
gfap	glial fibrillary acidic protein	0.018
robo2	roundabout homolog 2	0.018
gria4a	glutamate receptor, ionotropic, AMPA 4a	0.018
zic4	zic family member 4	0.018
fgf3	fibroblast growth factor 3	0.017
dlg4	discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)	0.017
cmn	calymmin	0.017
pbx1a	pre-B-cell leukemia transcription factor 1a	0.017
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.017
foxd5	forkhead box D5	0.017
arntl2	aryl hydrocarbon receptor nuclear translocator-like 2	0.016
tbr1b	T-box, brain, 1b	0.016
hoxd4a	homeo box D4a	0.016
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.016
ca5	carbonic anhydrase V	0.016
sox9b	SRY-box containing gene 9b	0.016
id2a	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a	0.016
sulf2	sulfatase 2	0.016
myl7	myosin, light polypeptide 7, regulatory	0.015
ctnnd2b	catenin (cadherin-associated protein), delta 2b	0.015
barx1	BarH-like homeobox 1	0.015
rgl2	ral guanine nucleotide dissociation stimulator-like 2	0.015
nrxn2a	neurexin 2a	0.015
hand2	heart and neural crest derivatives expressed transcript 2	0.015
sox3	SRY-box containing gene 3	0.015
tfeb	transcription factor EB	0.015
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.015
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.015
sox19b	SRY-box containing gene 19b	0.015
gdf6a	growth differentiation factor 6a	0.014
hoxb5b	homeo box B5b	0.014
mespb	mesoderm posterior b	0.014
hgfa	hepatocyte growth factor a	0.014
oprm1	opioid receptor, mu 1	0.014
wu:fj82b07	wu:fj82b07	0.014
nfasca	neurofascin homolog (chicken) a	0.014
hbae3	hemoglobin alpha embryonic-3	0.014
flh	floating head	0.014
p2rx8	purinergic receptor P2X, ligand-gated ion channel, 8	0.013
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.013
cdh4	cadherin 4, retinal	0.013
cadm1a	cell adhesion molecule 1a	0.013
lhx1b	LIM homeobox 1b	0.013	Zebrafish
her2	hairy-related 2	0.013
myca	myelocytomatosis oncogene a	0.013
jag2	jagged 2	0.013
lmo3	LIM domain only 3	0.013
gdf6b	growth differentiation factor 6b	0.013
alg3	asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)	0.012
tgfb3	transforming growth factor, beta 3	0.012
ret1	receptor tyrosine kinase	0.012
insm1a	insulinoma-associated 1a	0.012
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.012
nkx3.2	NK3 homeobox 2	0.012
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.012
sim2	single-minded homolog 2 (Drosophila)	0.012
cadm3	cell adhesion molecule 3	0.012
gsx1	GS homeobox 1	0.012
hoxb4a	homeo box B4a	0.012
crestin	crestin	0.012
pcdh17	protocadherin 17	0.012
mpp6b	membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)	0.012
nr2f1b	nuclear receptor subfamily 2, group F, member 1b	0.012
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.012
sb:cb1008	sb:cb1008	0.012
hcrt	hypocretin (orexin) neuropeptide precursor	0.011
fzd10	frizzled homolog 10	0.011
fgf8a	fibroblast growth factor 8 a	0.011
tpbgl	trophoblast glycoprotein-like	0.011
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.011
rbm19	RNA binding motif protein 19	0.011
ldb2b	LIM-domain binding factor 2b	0.011
prdm1a	PR domain containing 1a, with ZNF domain	0.011
bmp7b	bone morphogenetic protein 7b	0.011
nr5a2	nuclear receptor subfamily 5, group A, member 2	0.011
cntn1a	contactin 1a	0.011
tfec	transcription factor EC	0.010
pcdh18a	protocadherin 18a	0.010
prdm14	PR domain containing 14	0.010
etv2	ets variant gene 2	0.010
mycl1b	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) b	0.010
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.010
lmx1a	LIM homeobox transcription factor 1, alpha	0.010
creb1	cAMP responsive element binding protein 1	0.010
dab1a	disabled homolog 1a (Drosophila)	0.010
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.010