The network for 'receptor metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

receptor metabolic process

The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

Homo sapiens
Name Description Probability Func Analog Organism
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.998
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.871
TEK TEK tyrosine kinase, endothelial 0.785
ENG endoglin 0.774
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.772
PSEN1 presenilin 1 0.713
CCR5 chemokine (C-C motif) receptor 5 0.692
ZFYVE9 zinc finger, FYVE domain containing 9 0.618
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.605
ADRB1 adrenergic, beta-1-, receptor 0.578
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.550
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.517
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.504
HOXB5 homeobox B5 0.503
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.493
RARA retinoic acid receptor, alpha 0.477
THBS1 thrombospondin 1 0.475
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.446
EEA1 early endosome antigen 1 0.445
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.431
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.429
CXCL9 chemokine (C-X-C motif) ligand 9 0.384
DNM1 dynamin 1 0.381
IL8 interleukin 8 0.373
CXCL2 chemokine (C-X-C motif) ligand 2 0.355
LRP6 low density lipoprotein receptor-related protein 6 0.347
DNM2 dynamin 2 0.335
PTPRB protein tyrosine phosphatase, receptor type, B 0.322
CXCL3 chemokine (C-X-C motif) ligand 3 0.320
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.302
C1QA complement component 1, q subcomponent, A chain 0.299
FN1 fibronectin 1 0.299
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.297
ARRB2 arrestin, beta 2 0.292
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.287
SMAD4 SMAD family member 4 0.286
ITK IL2-inducible T-cell kinase 0.285
ARRB1 arrestin, beta 1 0.276
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.265
CALCRL calcitonin receptor-like 0.260
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.258
SH3GL3 SH3-domain GRB2-like 3 0.244
CXCL10 chemokine (C-X-C motif) ligand 10 0.240
FGA fibrinogen alpha chain 0.237
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.236
CXCL11 chemokine (C-X-C motif) ligand 11 0.235
NCOR2 nuclear receptor corepressor 2 0.233
RXRA retinoid X receptor, alpha 0.215
PICALM phosphatidylinositol binding clathrin assembly protein 0.210
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.202
HDAC6 histone deacetylase 6 0.195
CXCL5 chemokine (C-X-C motif) ligand 5 0.195
NRP1 neuropilin 1 0.191
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.191
ITGB4 integrin, beta 4 0.182
CCL2 chemokine (C-C motif) ligand 2 0.181
CCR2 chemokine (C-C motif) receptor 2 0.180
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.178
LDLR low density lipoprotein receptor 0.176
BBS10 Bardet-Biedl syndrome 10 0.170
IFNG interferon, gamma 0.169
STX4 syntaxin 4 0.167
HOXA5 homeobox A5 0.167
IL10RA interleukin 10 receptor, alpha 0.164
TLN1 talin 1 0.164
HP haptoglobin 0.161
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.160
CCL5 chemokine (C-C motif) ligand 5 0.159
IL6 interleukin 6 (interferon, beta 2) 0.159
ADRBK1 adrenergic, beta, receptor kinase 1 0.156
HOXA10 homeobox A10 0.155
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.154
SH3GL2 SH3-domain GRB2-like 2 0.148
PDIA3 protein disulfide isomerase family A, member 3 0.142
EPAS1 endothelial PAS domain protein 1 0.141
SNAP23 synaptosomal-associated protein, 23kDa 0.137
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.136
AMPH amphiphysin 0.129
A2M alpha-2-macroglobulin 0.128
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.125
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.122
CD28 CD28 molecule 0.122
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.121
ATXN3 ataxin 3 0.118
CCL20 chemokine (C-C motif) ligand 20 0.118
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 0.118
CXCR2 chemokine (C-X-C motif) receptor 2 0.116
CCL8 chemokine (C-C motif) ligand 8 0.116
APOC1 apolipoprotein C-I 0.115
UBE2D1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 0.115
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.114
DEDD death effector domain containing 0.113
SYNM synemin, intermediate filament protein 0.112
RNF11 ring finger protein 11 0.111
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.110
HOXB7 homeobox B7 0.109
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.109
NCOA6 nuclear receptor coactivator 6 0.109
SNX9 sorting nexin 9 0.108
IL22RA1 interleukin 22 receptor, alpha 1 0.107
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
ace-2 Protein ACE-2 0.327
ace-4 Protein ACE-4 0.229
F41E6.9 Protein F41E6.9 0.116
ace-1 Protein ACE-1 0.104
ace-3 Protein ACE-3 0.076
rpn-6.1 Protein RPN-6.1 0.057
daf-11 Protein DAF-11 0.050
dnc-2 Protein DNC-2 0.041
vps-37 Protein VPS-37 0.041
CELE_Y57G11C.3 Protein Y57G11C.3 0.036
C31E10.5 Protein C31E10.5 0.034
twk-18 Protein TWK-18 0.032
tag-353 Protein TAG-353 0.027
cka-1 Protein CKA-1 0.026
snap-1 Protein SNAP-1 0.025
F21C10.7 Protein F21C10.7 0.024
gpb-1 Protein GPB-1 0.023
ajm-1 Protein AJM-1 0.019
trim-9 Protein TRIM-9 0.019
pkg-1 Protein PKG-1 0.018
egl-44 Protein EGL-44 0.017
T22C1.6 Protein T22C1.6 0.017
CELE_T03F6.3 Protein T03F6.3 0.016
lmn-1 Protein LMN-1 0.015
lgc-34 Protein LGC-34 0.012
T27F6.7 Protein T27F6.7 0.012
ast-1 Protein AST-1 0.012
mvb-12 Protein MVB-12 0.012
rad-23 Protein RAD-23 0.012
F09A5.4 Protein F09A5.4 0.012
CELE_C25A1.5 Protein C25A1.5 0.011
K02A6.2 Protein K02A6.2 0.011
dnj-16 Protein DNJ-16 0.011
pqn-89 Protein PQN-89 0.011
C27C12.1 Protein C27C12.1 0.011
ehs-1 Protein EHS-1 0.010
lst-4 Protein LST-4 0.010
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Danio rerio
Name Description Probability Func Analog Organism
gria2a glutamate receptor, ionotropic, AMPA 2a 0.156
mib mind bomb 0.087
bc2 putative breast adenocarcinoma marker 0.080
dcc deleted in colorectal carcinoma 0.063
dzip1 DAZ interacting protein 1 0.055
gria2b glutamate receptor, ionotropic, AMPA 2b 0.040
gria4a glutamate receptor, ionotropic, AMPA 4a 0.034
chmp4b chromatin modifying protein 4B 0.026
epas1b endothelial PAS domain protein 1b 0.026
prkcq protein kinase C, theta 0.022
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.022
amotl2a angiomotin like 2a 0.020
dlg2 discs, large (Drosophila) homolog 2 0.017
aldocb aldolase C, fructose-bisphosphate, b 0.016
dlg1 discs, large (Drosophila) homolog 1 0.016
grin1a glutamate receptor, ionotropic, N-methyl D-aspartate 1a 0.015
hoxa13a homeo box A13a 0.014
zgc:77849 zgc:77849 0.014
pi4kb phosphatidylinositol 4-kinase, catalytic, beta 0.014
trpc5 transient receptor potential cation channel, subfamily C, member 5 0.013
igfbp1a insulin-like growth factor binding protein 1a 0.013
ghrb growth hormone receptor b 0.013
rcv1 recoverin 0.012
ssbp3b single stranded DNA binding protein 3b 0.012
ube2d1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 0.011
klf2b Kruppel-like factor 2b 0.011
zgc:103663 zgc:103663 0.011
cacna1ab calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b 0.010
cxcr4b chemokine (C-X-C motif), receptor 4b 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Grip1 glutamate receptor interacting protein 1 0.800
Baiap2 BAI1-associated protein 2 0.431
Fgf7 fibroblast growth factor 7 0.329
Gabrr1 gamma-aminobutyric acid (GABA) receptor, rho 1 0.300
Gria3 glutamate receptor, ionotrophic, AMPA 3 0.255
Cd80 Cd80 molecule 0.232
Hpcal1 hippocalcin-like 1 0.203
Sec23a Sec23 homolog A (S. cerevisiae) 0.152
Gria2 glutamate receptor, ionotropic, AMPA 2 0.147
Mmp13 matrix metallopeptidase 13 0.146
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.145
Trhr thyrotropin releasing hormone receptor 0.136
Apbb3 amyloid beta (A4) precursor protein-binding, family B, member 3 0.133
Atp6v1b2 ATPase, H transporting, lysosomal V1 subunit B2 0.125
Ap2b1 adaptor-related protein complex 2, beta 1 subunit 0.123
Dbp D site of albumin promoter (albumin D-box) binding protein 0.118
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.114
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.106
Amph amphiphysin 0.102
Accn3 amiloride-sensitive cation channel 3 0.098
Dgkz diacylglycerol kinase zeta 0.098
Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) 0.097
Impg2 interphotoreceptor matrix proteoglycan 2 0.095
Syt6 synaptotagmin VI 0.089
Ptms parathymosin 0.088
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.082
Cma1 chymase 1, mast cell 0.082
Grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.077
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.075
Cacnb4 calcium channel, voltage-dependent, beta 4 subunit 0.074
Kcna6 potassium voltage gated channel, shaker related subfamily, member 6 0.071
Map2 microtubule-associated protein 2 0.071
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.069
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.065
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.064
Akr1c14 aldo-keto reductase family 1, member C14 0.062
Dlg4 discs, large homolog 4 (Drosophila) 0.062
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.060
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.060
Mag myelin-associated glycoprotein 0.056
Shank1 SH3 and multiple ankyrin repeat domains 1 0.056
Plcg1 phospholipase C, gamma 1 0.054
Ndfip2 Nedd4 family interacting protein 2 0.053
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.051
Cast calpastatin 0.050
Fbxo30 F-box protein 30 0.050
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.050
Pfn1 profilin 1 0.047
Mmp3 matrix metallopeptidase 3 0.047
Gtf2a1 general transcription factor IIA, 1 0.046
Ascl2 achaete-scute complex homolog 2 (Drosophila) 0.046
Prph2 peripherin 2 0.046
Sec24d SEC24 family, member D (S. cerevisiae) 0.045
Dnm1 dynamin 1 0.044
Robo2 roundabout homolog 2 (Drosophila) 0.043
Prkch protein kinase C, eta 0.041
Ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.040
Fgf2 fibroblast growth factor 2 0.040
Efhd2 EF-hand domain family, member D2 0.039
Nudt16l1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 0.039
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.039
Lect1 leukocyte cell derived chemotaxin 1 0.038
Acrv1 acrosomal vesicle protein 1 0.038
Gal galanin prepropeptide 0.038
Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.037
Gpr1 G protein-coupled receptor 1 0.036
Arcn1 archain 1 0.036
Efna5 ephrin A5 0.034
Mmp9 matrix metallopeptidase 9 0.034
Plat plasminogen activator, tissue 0.034
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.033
Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) 0.033
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.033
Lif leukemia inhibitory factor 0.032
Scarb1 scavenger receptor class B, member 1 0.032
Il1rn interleukin 1 receptor antagonist 0.032
Mrgprf MAS-related GPR, member F 0.031
Ncaph2 non-SMC condensin II complex, subunit H2 0.031
Mertk c-mer proto-oncogene tyrosine kinase 0.031
Epha7 Eph receptor A7 0.030
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.030
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.029
Il8ra interleukin 8 receptor, alpha 0.029
Ptma prothymosin alpha 0.029
Arrb2 arrestin, beta 2 0.029
Mapk10 mitogen activated protein kinase 10 0.028
Adrb2 adrenergic, beta-2-, receptor, surface 0.028
Drd1a dopamine receptor D1A 0.027
Bak1 BCL2-antagonist/killer 1 0.027
Gfra1 GDNF family receptor alpha 1 0.026
Dio3 deiodinase, iodothyronine, type III 0.026
Foxa1 forkhead box A1 0.026
Il1r1 interleukin 1 receptor, type I 0.026
Cd46 CD46 molecule, complement regulatory protein 0.026
Nlgn1 neuroligin 1 0.026
Pcnxl3 pecanex-like 3 (Drosophila) 0.025
Il17re interleukin 17 receptor E 0.025
Kcnip4 Kv channel interacting protein 4 0.025
Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 0.025
Lepr leptin receptor 0.025
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
PEX10 Pex10p 0.576
GDI1 Gdi1p 0.575
YPT1 Ypt1p 0.399
YPT10 Ypt10p 0.097
PEX1 Pex1p 0.081
YPT52 Ypt52p 0.074
PEX5 Pex5p 0.052
SLA2 Sla2p 0.049
PEX6 Pex6p 0.038
PEX22 Pex22p 0.037
AKL1 Akl1p 0.037
VPS21 Vps21p 0.034
TFA1 Tfa1p 0.031
PEX15 Pex15p 0.025
PEX14 Pex14p 0.024
UGO1 Ugo1p 0.023
PEX12 Pex12p 0.022
PEX4 Pex4p 0.022
ALY1 Aly1p 0.020
ARG8 Arg8p 0.020
TFB4 Tfb4p 0.020
VPS8 Vps8p 0.020
CCL1 Ccl1p 0.019
TRA1 Tra1p 0.015
FAB1 Fab1p 0.013
YBL039W-B hypothetical protein 0.013
ROG3 Rog3p 0.012
PEX8 Pex8p 0.012
SRD1 Srd1p 0.012
YLR264C-A hypothetical protein 0.011
CUP1-1 Cup1-1p 0.011
SEC21 Sec21p 0.011
LEU2 Leu2p 0.011
UBR2 Ubr2p 0.011
END3 End3p 0.011
PEX13 Pex13p 0.011
UPS3 Ups3p 0.011
YGR102C hypothetical protein 0.010