The network for 'histone h4 acetylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

histone h4 acetylation

The modification of histone H4 by the addition of an acetyl group.

Homo sapiens
Name Description Probability Func Analog Organism
C20orf20 chromosome 20 open reading frame 20 1.000
TP53 tumor protein p53 1.000
CREBBP CREB binding protein 0.999
BRCA1 breast cancer 1, early onset 0.998
RUVBL1 RuvB-like 1 (E. coli) 0.992
ACTL6A actin-like 6A 0.992
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.984
TRRAP transformation/transcription domain-associated protein 0.970
EP300 E1A binding protein p300 0.970
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.951
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.947
WDR5 WD repeat domain 5 0.923
ELP2 elongation protein 2 homolog (S. cerevisiae) 0.898
HTT huntingtin 0.893
YY1 YY1 transcription factor 0.890
TADA3 transcriptional adaptor 3 0.885
ESR1 estrogen receptor 1 0.882
SIRT1 sirtuin 1 0.879
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.874
KAT2B K(lysine) acetyltransferase 2B 0.838
ELP3 elongation protein 3 homolog (S. cerevisiae) 0.825
LRP1 low density lipoprotein receptor-related protein 1 0.789
DAXX death-domain associated protein 0.740
NCOA2 nuclear receptor coactivator 2 0.730
MRFAP1 Morf4 family associated protein 1 0.705
MYST3 MYST histone acetyltransferase (monocytic leukemia) 3 0.696
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.691
CCDC101 coiled-coil domain containing 101 0.691
ING5 inhibitor of growth family, member 5 0.670
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.626
ING3 inhibitor of growth family, member 3 0.615
ELP4 elongation protein 4 homolog (S. cerevisiae) 0.586
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.572
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.567
AR androgen receptor 0.541
DOT1L DOT1-like, histone H3 methyltransferase (S. cerevisiae) 0.530
ZNF496 zinc finger protein 496 0.508
KAT2A K(lysine) acetyltransferase 2A 0.507
NCOA1 nuclear receptor coactivator 1 0.490
DMAP1 DNA methyltransferase 1 associated protein 1 0.487
HIST1H3B histone cluster 1, H3b 0.476
MBIP MAP3K12 binding inhibitory protein 1 0.467
INO80 INO80 homolog (S. cerevisiae) 0.449
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.434
KAT5 K(lysine) acetyltransferase 5 0.426
MYST1 MYST histone acetyltransferase 1 0.410
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.406
CCNT1 cyclin T1 0.384
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.380
FUBP1 far upstream element (FUSE) binding protein 1 0.379
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.340
NBN nibrin 0.288
HIST2H3C histone cluster 2, H3c 0.257
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.248
INO80E INO80 complex subunit E 0.238
SP1 Sp1 transcription factor 0.230
ARRB1 arrestin, beta 1 0.227
HIST1H4F histone cluster 1, H4f 0.211
HIC1 hypermethylated in cancer 1 0.191
EP400 E1A binding protein p400 0.190
PML promyelocytic leukemia 0.185
ATG3 ATG3 autophagy related 3 homolog (S. cerevisiae) 0.184
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.161
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.158
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.158
CREBZF CREB/ATF bZIP transcription factor 0.153
USP22 ubiquitin specific peptidase 22 0.139
MEN1 multiple endocrine neoplasia I 0.128
UBE3A ubiquitin protein ligase E3A 0.128
FOXO1 forkhead box O1 0.127
BARD1 BRCA1 associated RING domain 1 0.124
WRN Werner syndrome, RecQ helicase-like 0.121
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.116
BRD8 bromodomain containing 8 0.115
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.114
MRFAP1L1 Morf4 family associated protein 1-like 1 0.113
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 0.113
CEP70 centrosomal protein 70kDa 0.110
NCOA6 nuclear receptor coactivator 6 0.106
DDX5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 0.105
HIPK2 homeodomain interacting protein kinase 2 0.104
TGIF1 TGFB-induced factor homeobox 1 0.102
MAPK10 mitogen-activated protein kinase 10 0.101
ATM ataxia telangiectasia mutated 0.100
GNMT glycine N-methyltransferase 0.095
HDAC1 histone deacetylase 1 0.094
RXRA retinoid X receptor, alpha 0.093
JUP junction plakoglobin 0.092
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.092
THAP11 THAP domain containing 11 0.092
SCAF8 SR-related CTD-associated factor 8 0.089
PIAS4 protein inhibitor of activated STAT, 4 0.088
YEATS4 YEATS domain containing 4 0.086
ATXN7 ataxin 7 0.085
TCF4 transcription factor 4 0.074
RUVBL2 RuvB-like 2 (E. coli) 0.072
NINL ninein-like 0.072
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.071
HCFC1 host cell factor C1 (VP16-accessory protein) 0.069
IP6K2 inositol hexakisphosphate kinase 2 0.067
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
dik diskette 0.932
Pcaf CG4107 gene product from transcript CG4107-RA 0.914
msl-3 male-specific lethal 3 0.875
Hcf Host cell factor 0.863
mod(mdg4) modifier of mdg4 0.833
CG10414 CG10414 gene product from transcript CG10414-RA 0.815
wds will die slowly 0.779
brm brahma 0.590
msl-2 male-specific lethal 2 0.581
pr-set7 CG3307 gene product from transcript CG3307-RC 0.557
msl-1 male-specific lethal 1 0.535
Snr1 Snf5-related 1 0.478
Nipped-A CG33554 gene product from transcript CG33554-RE 0.454
mle maleless 0.413
Tao-1 CG14217 gene product from transcript CG14217-RF 0.380
Chrac-14 CG13399 gene product from transcript CG13399-RA 0.349
D12 CG13400 gene product from transcript CG13400-RA 0.347
mof males absent on the first 0.330
Atac1 ATAC component 1 0.320
egg eggless 0.304
lid little imaginal discs 0.240
Gmd GDP-mannose 4,6-dehydratase 0.226
Mocs2 Molybdopterin synthase 2 0.220
Atg1 Autophagy-specific gene 1 0.170
dco discs overgrown 0.164
B52 CG10851 gene product from transcript CG10851-RB 0.137
CG14614 CG14614 gene product from transcript CG14614-RA 0.125
Taf5 TBP-associated factor 5 0.123
CTCF CG8591 gene product from transcript CG8591-RA 0.123
His2Av Histone H2A variant 0.111
Sgf29 CG30390 gene product from transcript CG30390-RA 0.105
trx trithorax 0.100
cg combgap 0.090
CG10880 CG10880 gene product from transcript CG10880-RA 0.080
e(y)3 enhancer of yellow 3 0.080
krz kurtz 0.076
NC2beta CG4185 gene product from transcript CG4185-RA 0.074
Sce Sex combs extra 0.074
barr barren 0.071
vir virilizer 0.066
simj simjang 0.063
ash2 absent, small, or homeotic discs 2 0.059
Su(var)3-3 Suppressor of variegation 3-3 0.057
Saf6 SAGA factor-like TAF6 0.055
Traf6 TNF-receptor-associated factor 6 0.054
MRG15 CG6363 gene product from transcript CG6363-RA 0.054
CG16812 CG16812 gene product from transcript CG16812-RA 0.051
fs(1)h female sterile (1) homeotic 0.047
Su(H) Suppressor of Hairless 0.046
Hr39 Hormone receptor-like in 39 0.046
rno rhinoceros 0.043
rdx roadkill 0.042
tsr twinstar 0.041
her hermaphrodite 0.040
phl pole hole 0.040
SF2 CG6987 gene product from transcript CG6987-RA 0.039
Tango6 Transport and Golgi organization 6 0.037
pan pangolin 0.035
prod proliferation disrupter 0.034
CSN6 COP9 complex homolog subunit 6 0.034
Ptp69D Protein tyrosine phosphatase 69D 0.034
l(3)mbt lethal (3) malignant brain tumor 0.033
fend forked end 0.032
CG16908 CG16908 gene product from transcript CG16908-RA 0.030
CG6116 CG6116 gene product from transcript CG6116-RA 0.028
ph-d polyhomeotic distal 0.028
Pka-C1 cAMP-dependent protein kinase 1 0.028
CG8165 CG8165 gene product from transcript CG8165-RA 0.027
Pc Polycomb 0.027
me31B maternal expression at 31B 0.026
hkl hook-like 0.025
Atg7 Autophagy-specific gene 7 0.024
Scm Sex comb on midleg 0.023
ash1 absent, small, or homeotic discs 1 0.023
CG6254 CG6254 gene product from transcript CG6254-RA 0.022
hep hemipterous 0.022
lwr lesswright 0.022
caz cabeza 0.021
CG5222 CG5222 gene product from transcript CG5222-RA 0.021
ctp cut up 0.021
sbb scribbler 0.020
RASSF8 CG5053 gene product from transcript CG5053-RA 0.020
Eip63E Ecdysone-induced protein 63E 0.019
CG5694 CG5694 gene product from transcript CG5694-RA 0.018
CG32016 CG32016 gene product from transcript CG32016-RB 0.018
CG9339 CG9339 gene product from transcript CG9339-RG 0.017
BRWD3 CG31132 gene product from transcript CG31132-RA 0.016
Tip60 CG6121 gene product from transcript CG6121-RA 0.016
CG1347 CG1347 gene product from transcript CG1347-RB 0.016
Rsf1 Repressor splicing factor 1 0.016
pzg putzig 0.015
cdc16 CG6759 gene product from transcript CG6759-RA 0.015
rnh1 ribonuclease H1 0.015
CG32343 CG32343 gene product from transcript CG32343-RB 0.015
CG12042 CG12042 gene product from transcript CG12042-RA 0.015
Taf7 TBP-associated factor 7 0.014
Nf-YB Nuclear factor Y-box B 0.014
Eip75B Ecdysone-induced protein 75B 0.014
key kenny 0.014
Mfap1 Microfibril-associated protein 1 0.014
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Mus musculus
Name Description Probability Func Analog Organism
Trrap transformation/transcription domain-associated protein 0.991
Arid1a AT rich interactive domain 1A (SWI-like) 0.979
Dmap1 DNA methyltransferase 1-associated protein 1 0.926
Crebbp CREB binding protein 0.901
Ep400 E1A binding protein p400 0.897
Per2 period homolog 2 (Drosophila) 0.861
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.829
Kat5 K(lysine) acetyltransferase 5 0.772
Trp53 transformation related protein 53 0.710
Pou5f1 POU domain, class 5, transcription factor 1 0.707
Ep300 E1A binding protein p300 0.688
Mll1 myeloid/lymphoid or mixed-lineage leukemia 1 0.688
Ddx17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.574
Tcf4 transcription factor 4 0.495
Brca1 breast cancer 1 0.477
Cry2 cryptochrome 2 (photolyase-like) 0.439
Stat2 signal transducer and activator of transcription 2 0.421
Clock circadian locomotor output cycles kaput 0.383
Atg12 autophagy-related 12 (yeast) 0.372
Tcfcp2l1 transcription factor CP2-like 1 0.343
Kat2a K(lysine) acetyltransferase 2A 0.323
Arrb2 arrestin, beta 2 0.308
Isg15 ISG15 ubiquitin-like modifier 0.264
Tcf3 transcription factor 3 0.242
Mll3 myeloid/lymphoid or mixed-lineage leukemia 3 0.229
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.186
Ikzf1 IKAROS family zinc finger 1 0.181
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.165
Igh immunoglobulin heavy chain complex 0.159
Rnf44 ring finger protein 44 0.156
Tnrc6c trinucleotide repeat containing 6C 0.154
Csnk1e casein kinase 1, epsilon 0.146
Wdr5 WD repeat domain 5 0.146
Sfpi1 SFFV proviral integration 1 0.144
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 0.134
Sin3a transcriptional regulator, SIN3A (yeast) 0.134
Polr2a polymerase (RNA) II (DNA directed) polypeptide A 0.130
Rbbp5 retinoblastoma binding protein 5 0.123
Arid2 AT rich interactive domain 2 (ARID, RFX-like) 0.121
Hcfc1 host cell factor C1 0.121
Irf4 interferon regulatory factor 4 0.118
Brd4 bromodomain containing 4 0.111
Atm ataxia telangiectasia mutated homolog (human) 0.096
Esr1 estrogen receptor 1 (alpha) 0.095
Cbfa2t3 core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) 0.094
Bptf bromodomain PHD finger transcription factor 0.093
Carm1 coactivator-associated arginine methyltransferase 1 0.092
Nanog Nanog homeobox 0.090
Arid1b AT rich interactive domain 1B (SWI-like) 0.087
Ncoa3 nuclear receptor coactivator 3 0.086
Runx1 runt related transcription factor 1 0.080
Ldb1 LIM domain binding 1 0.077
Irgm2 immunity-related GTPase family M member 2 0.072
Ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.071
Scaf4 SR-related CTD-associated factor 4 0.070
Zmynd11 zinc finger, MYND domain containing 11 0.065
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.065
Bap1 Brca1 associated protein 1 0.063
Acin1 apoptotic chromatin condensation inducer 1 0.062
Sox2 SRY-box containing gene 2 0.057
Unc93b1 unc-93 homolog B1 (C. elegans) 0.055
Max Max protein 0.053
Axin1 axin 1 0.052
Myc myelocytomatosis oncogene 0.051
Sfn stratifin 0.050
Thra thyroid hormone receptor alpha 0.050
Macf1 microtubule-actin crosslinking factor 1 0.050
Atxn7l3 ataxin 7-like 3 0.050
Tapbp TAP binding protein 0.049
Smarcc2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.049
Cd79b CD79B antigen 0.049
Mll5 myeloid/lymphoid or mixed-lineage leukemia 5 0.047
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.046
Cdk9 cyclin-dependent kinase 9 (CDC2-related kinase) 0.046
Kdm5b lysine (K)-specific demethylase 5B 0.046
Trp63 transformation related protein 63 0.045
Kdm1a lysine (K)-specific demethylase 1A 0.045
Nbn nibrin 0.044
Prpf8 pre-mRNA processing factor 8 0.044
Myod1 myogenic differentiation 1 0.043
Pum1 pumilio 1 (Drosophila) 0.043
Smad4 MAD homolog 4 (Drosophila) 0.041
Uba7 ubiquitin-like modifier activating enzyme 7 0.040
Ctnnb1 catenin (cadherin associated protein), beta 1 0.039
Tal1 T-cell acute lymphocytic leukemia 1 0.039
Atg10 autophagy-related 10 (yeast) 0.037
Tmem131 transmembrane protein 131 0.036
Gsk3b glycogen synthase kinase 3 beta 0.036
Apc adenomatosis polyposis coli 0.035
Traf6 TNF receptor-associated factor 6 0.034
Mecp2 methyl CpG binding protein 2 0.034
Fam76b family with sequence similarity 76, member B 0.034
Chd4 chromodomain helicase DNA binding protein 4 0.033
Trim28 tripartite motif-containing 28 0.033
Sf1 splicing factor 1 0.033
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.033
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.033
Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.032
Csnk1d casein kinase 1, delta 0.032
Tcf7 transcription factor 7, T-cell specific 0.031
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism