The network for 'cellular response to ketone' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to ketone

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus.

Mus musculus
Name Description Probability Func Analog Organism
LOC100048884 novel member of the major urinary protein (Mup) gene family 0.332
Mup10 major urinary protein 10 0.244
Foxc1 forkhead box C1 0.189
Ptgs2 prostaglandin-endoperoxide synthase 2 0.188
Egfr epidermal growth factor receptor 0.180
Mup19 major urinary protein 19 0.167
Lep leptin 0.149
Mup9 major urinary protein 9 0.132
Akr1c6 aldo-keto reductase family 1, member C6 0.125
Sfrp2 secreted frizzled-related protein 2 0.119
Lepr leptin receptor 0.102
Fas Fas (TNF receptor superfamily member 6) 0.074
Mup5 major urinary protein 5 0.070
Vegfa vascular endothelial growth factor A 0.064
Tgfb1 transforming growth factor, beta 1 0.059
Gbp5 guanylate binding protein 5 0.054
Slc12a1 solute carrier family 12, member 1 0.053
Mup11 major urinary protein 11 0.052
Mup7 major urinary protein 7 0.050
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.050
Mup13 major urinary protein 13 0.048
Ren1 renin 1 structural 0.048
Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 0.048
Socs1 suppressor of cytokine signaling 1 0.048
Plau plasminogen activator, urokinase 0.048
Mup8 major urinary protein 8 0.047
H2-Aa histocompatibility 2, class II antigen A, alpha 0.047
Mup4 major urinary protein 4 0.046
Slco1b2 solute carrier organic anion transporter family, member 1b2 0.046
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.044
Insr insulin receptor 0.041
Mup12 major urinary protein 12 0.041
Pten phosphatase and tensin homolog 0.041
Mup1 major urinary protein 1 0.040
F13b coagulation factor XIII, beta subunit 0.039
Mup17 major urinary protein 17 0.039
Nos1 nitric oxide synthase 1, neuronal 0.039
Mup2 major urinary protein 2 0.036
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.036
Il1b interleukin 1 beta 0.035
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.034
Nr2e1 nuclear receptor subfamily 2, group E, member 1 0.033
Mup14 major urinary protein 14 0.032
Nos3 nitric oxide synthase 3, endothelial cell 0.032
Mup3 major urinary protein 3 0.031
Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.031
LOC100048885 major urinary protein LOC100048885 0.031
Pomc pro-opiomelanocortin-alpha 0.030
Aire autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) 0.029
Slco1a1 solute carrier organic anion transporter family, member 1a1 0.028
Mup15 major urinary protein 15 0.028
Keg1 kidney expressed gene 1 0.027
Mmp3 matrix metallopeptidase 3 0.026
Vhl von Hippel-Lindau tumor suppressor 0.026
Akr1c21 aldo-keto reductase family 1, member C21 0.025
Bmp4 bone morphogenetic protein 4 0.024
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.023
Pparg peroxisome proliferator activated receptor gamma 0.023
Mug2 murinoglobulin 2 0.023
Agtr1a angiotensin II receptor, type 1a 0.023
Dmd dystrophin, muscular dystrophy 0.023
Rdh7 retinol dehydrogenase 7 0.022
Msx2 homeobox, msh-like 2 0.022
Il18 interleukin 18 0.022
Crp C-reactive protein, pentraxin-related 0.022
Rxra retinoid X receptor alpha 0.022
Otc ornithine transcarbamylase 0.021
Dsg4 desmoglein 4 0.021
Elovl3 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 0.021
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.021
Clec4d C-type lectin domain family 4, member d 0.020
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.020
Il1a interleukin 1 alpha 0.019
Cyp2j5 cytochrome P450, family 2, subfamily j, polypeptide 5 0.019
Hif1a hypoxia inducible factor 1, alpha subunit 0.018
Adam17 a disintegrin and metallopeptidase domain 17 0.018
C9 complement component 9 0.018
Cfhr1 complement factor H-related 1 0.017
Nos2 nitric oxide synthase 2, inducible 0.017
Stat3 signal transducer and activator of transcription 3 0.017
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.017
Gja1 gap junction protein, alpha 1 0.017
Ccr2 chemokine (C-C motif) receptor 2 0.017
Ptk2 PTK2 protein tyrosine kinase 2 0.016
Twist2 twist homolog 2 (Drosophila) 0.016
Vdr vitamin D receptor 0.016
Hao1 hydroxyacid oxidase 1, liver 0.016
Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 0.016
Tead3 TEA domain family member 3 0.015
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.015
Pla2r1 phospholipase A2 receptor 1 0.015
Acvr1b activin A receptor, type 1B 0.015
Umod uromodulin 0.015
Grpr gastrin releasing peptide receptor 0.015
Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 0.015
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.015
Nf1 neurofibromatosis 1 0.015
Htra3 HtrA serine peptidase 3 0.014
Agtrap angiotensin II, type I receptor-associated protein 0.014
Adipoq adiponectin, C1Q and collagen domain containing 0.014
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
usp ultraspiracle 0.255
CG13310 CG13310 gene product from transcript CG13310-RA 0.138
Dscam Down syndrome cell adhesion molecule 0.097
Src64B Src oncogene at 64B 0.097
pzg putzig 0.093
gcl germ cell-less 0.087
MED6 Mediator complex subunit 6 0.086
cg combgap 0.076
Sgs4 Salivary gland secretion 4 0.056
eas easily shocked 0.048
Chro Chromator 0.047
CG10562 CG10562 gene product from transcript CG10562-RA 0.041
gfA giant fibre A 0.040
Mgat1 UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I 0.039
myoglianin CG1838 gene product from transcript CG1838-RD 0.037
Su(var)2-HP2 CG12864 gene product from transcript CG12864-RB 0.037
fne found in neurons 0.037
CG11149 CG11149 gene product from transcript CG11149-RD 0.036
InR Insulin-like receptor 0.035
esn espinas 0.033
CG31958 CG31958 gene product from transcript CG31958-RA 0.033
Cyp6d4 CG12800 gene product from transcript CG12800-RA 0.032
CG8773 CG8773 gene product from transcript CG8773-RB 0.032
Jarid2 CG3654 gene product from transcript CG3654-RD 0.030
Hr51 Hormone receptor 51 0.030
CG32810 CG32810 gene product from transcript CG32810-RB 0.030
CG3638 CG3638 gene product from transcript CG3638-RE 0.028
CG13032 CG13032 gene product from transcript CG13032-RA 0.027
ftz-f1 ftz transcription factor 1 0.027
TBPH CG10327 gene product from transcript CG10327-RC 0.027
Tango6 Transport and Golgi organization 6 0.027
Ten-a Tenascin accessory 0.027
CG1941 CG1941 gene product from transcript CG1941-RA 0.026
uri unconventional prefoldin RPB5 interactor 0.026
fkh fork head 0.026
Ugt86Dj CG15902 gene product from transcript CG15902-RA 0.025
tara taranis 0.025
tna tonalli 0.023
CG12020 CG12020 gene product from transcript CG12020-RA 0.023
l(2)35Bg lethal (2) 35Bg 0.022
Cyp6a13 CG2397 gene product from transcript CG2397-RA 0.021
dco discs overgrown 0.021
sinah sina homologue 0.021
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.020
CG34168 CG34168 gene product from transcript CG34168-RA 0.020
CG6465 CG6465 gene product from transcript CG6465-RA 0.020
east enhanced adult sensory threshold 0.019
Sfmbt Scm-related gene containing four mbt domains 0.019
CG15784 CG15784 gene product from transcript CG15784-RA 0.019
Tm1 Tropomyosin 1 0.019
Mi-2 CG8103 gene product from transcript CG8103-RA 0.019
nej nejire 0.018
CG1965 CG1965 gene product from transcript CG1965-RA 0.018
CG14047 CG14047 gene product from transcript CG14047-RH 0.018
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.018
Iswi Imitation SWI 0.017
Ugt86Dh CG4772 gene product from transcript CG4772-RA 0.017
Fkbp13 CG9847 gene product from transcript CG9847-RC 0.017
CG31792 CG31792 gene product from transcript CG31792-RA 0.017
CG10051 CG10051 gene product from transcript CG10051-RA 0.017
pb proboscipedia 0.017
Cyp4ac1 CG14032 gene product from transcript CG14032-RA 0.017
CG4328 CG4328 gene product from transcript CG4328-RB 0.017
bip1 CG7574 gene product from transcript CG7574-RA 0.016
Sgs5 Salivary gland secretion 5 0.016
CG4239 CG4239 gene product from transcript CG4239-RA 0.016
CG33012 CG33012 gene product from transcript CG33012-RA 0.016
CG17221 CG17221 gene product from transcript CG17221-RB 0.016
CG17026 CG17026 gene product from transcript CG17026-RA 0.016
CG9960 CG9960 gene product from transcript CG9960-RA 0.015
Cyp28a5 CG8864 gene product from transcript CG8864-RA 0.015
MED1 Mediator complex subunit 1 0.015
Ugt86Dc CG4739 gene product from transcript CG4739-RA 0.015
bwa brain washing 0.015
wdb widerborst 0.015
CG34376 CG34376 gene product from transcript CG34376-RB 0.014
Cyp12e1 CG14680 gene product from transcript CG14680-RC 0.014
CG5724 CG5724 gene product from transcript CG5724-RA 0.014
toy twin of eyeless 0.014
CG10560 CG10560 gene product from transcript CG10560-RA 0.014
CG5361 CG5361 gene product from transcript CG5361-RA 0.014
Ugt37b1 UDP-glycosyltransferase 37b1 0.014
CG2064 CG2064 gene product from transcript CG2064-RA 0.014
retn retained 0.014
Sgs7 Salivary gland secretion 7 0.014
PrBP Prenyl-binding protein 0.014
btl breathless 0.014
CG14457 CG14457 gene product from transcript CG14457-RA 0.013
G9a CG2995 gene product from transcript CG2995-RA 0.013
Ugt35a UDP-glycosyltransferase 35a 0.013
trk trunk 0.013
CG11093 CG11093 gene product from transcript CG11093-RB 0.013
JhI-26 Juvenile hormone-inducible protein 26 0.013
Usf CG17592 gene product from transcript CG17592-RB 0.013
CG4302 CG4302 gene product from transcript CG4302-RA 0.013
CG13285 CG13285 gene product from transcript CG13285-RA 0.013
klu klumpfuss 0.013
ATbp (A+T)-stretch binding protein 0.012
spn-F CG12114 gene product from transcript CG12114-RA 0.012
mrt martik 0.012
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Homo sapiens
Name Description Probability Func Analog Organism
PLAU plasminogen activator, urokinase 0.079
NRP1 neuropilin 1 0.061
AXL AXL receptor tyrosine kinase 0.033
ENG endoglin 0.032
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.031
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.028
APAF1 apoptotic peptidase activating factor 1 0.021
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.018
CCR5 chemokine (C-C motif) receptor 5 0.017
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.016
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.016
VEZF1 vascular endothelial zinc finger 1 0.015
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.014
SOCS1 suppressor of cytokine signaling 1 0.013
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.012
FSTL1 follistatin-like 1 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-Ba RT1 class II, locus Ba 0.622
Ccl2 chemokine (C-C motif) ligand 2 0.372
Cd14 CD14 molecule 0.353
Il1b interleukin 1 beta 0.340
Ccl3 chemokine (C-C motif) ligand 3 0.205
Cp ceruloplasmin 0.201
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.198
RT1-Bb RT1 class II, locus Bb 0.184
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.179
Agtr1a angiotensin II receptor, type 1a 0.176
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.161
Ccl4 chemokine (C-C motif) ligand 4 0.143
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C 0.136
Cxcl10 chemokine (C-X-C motif) ligand 10 0.131
Plau plasminogen activator, urokinase 0.131
Vcan versican 0.125
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.125
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.122
G6pc glucose-6-phosphatase, catalytic subunit 0.119
Il1a interleukin 1 alpha 0.116
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.114
RGD1564327 similar to integrin alpha 8 0.105
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.103
Mmp12 matrix metallopeptidase 12 0.099
Ptgs2 prostaglandin-endoperoxide synthase 2 0.097
Sult2al1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1 0.097
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.095
Cd37 CD37 molecule 0.094
Pparg peroxisome proliferator-activated receptor gamma 0.088
Galnt5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) 0.088
B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.087
Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 0.081
Mef2d myocyte enhancer factor 2D 0.078
Akr1c14 aldo-keto reductase family 1, member C14 0.075
Anpep alanyl (membrane) aminopeptidase 0.075
Ces1f carboxylesterase 1F 0.075
P22k15 cystatin related protein 2 0.074
Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 0.073
Cd44 Cd44 molecule 0.069
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.068
Bgn biglycan 0.067
Jak1 Janus kinase 1 0.067
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.067
Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 0.066
Cxcl2 chemokine (C-X-C motif) ligand 2 0.066
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.065
Cyb5a cytochrome b5 type A (microsomal) 0.064
Lbp lipopolysaccharide binding protein 0.064
Crygf crystallin, gamma F 0.064
Pigr polymeric immunoglobulin receptor 0.064
Plek pleckstrin 0.064
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.063
Lox lysyl oxidase 0.062
Ccl20 chemokine (C-C motif) ligand 20 0.062
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.062
Vom1r100 vomeronasal 1 receptor 100 0.061
Pgr progesterone receptor 0.061
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.060
Gja1 gap junction protein, alpha 1 0.059
Acsm2 acyl-CoA synthetase medium-chain family member 2 0.058
LOC100361547 Cytochrome P450, family 2, subfamily c, polypeptide 7-like 0.058
Ptgfr prostaglandin F receptor 0.058
Pla1a phospholipase A1 member A 0.057
Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.057
Mgst2 microsomal glutathione S-transferase 2 0.056
Smad1 SMAD family member 1 0.056
Adam17 ADAM metallopeptidase domain 17 0.056
Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 0.056
C8b complement component 8, beta polypeptide 0.054
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.054
Selp selectin P 0.053
LOC100361864 UDP-glucuronosyltransferase 2B3-like 0.053
Nrg2 neuregulin 2 0.053
Dpep1 dipeptidase 1 (renal) 0.052
Gucy2d guanylate cyclase 2d 0.050
Aqp4 aquaporin 4 0.050
Gabrp gamma-aminobutyric acid (GABA-A) receptor, pi 0.050
Akr1c12 aldo-keto reductase family 1, member C12 0.050
Mmp3 matrix metallopeptidase 3 0.050
Qpct glutaminyl-peptide cyclotransferase 0.049
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.049
Hmox1 heme oxygenase (decycling) 1 0.049
Onecut1 one cut homeobox 1 0.048
Psgb1 pregnancy-specific beta 1-glycoprotein 0.048
Pcdhga11 protocadherin gamma subfamily A, 11 0.047
Met met proto-oncogene 0.047
Pth1r parathyroid hormone 1 receptor 0.046
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.046
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.046
Tcrb T-cell receptor beta chain 0.046
Vom1r101 vomeronasal 1 receptor 101 0.046
Prkcb protein kinase C, beta 0.046
Myo1a myosin IA 0.045
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.045
Icam1 intercellular adhesion molecule 1 0.045
Ugt2b37 UDP-glucuronosyltransferase 2 family, member 37 0.045
RT1-M5 RT1 class Ib, locus M5 0.045
Akr1c18 aldo-keto reductase family 1, member C18 0.044
Tas2r107 taste receptor, type 2, member 107 0.044
Pnlip pancreatic lipase 0.044
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
UBI4 Ubi4p 0.023
FEN1 Fen1p 0.013
SUR4 Sur4p 0.012
GIS2 Gis2p 0.010