The network for 'regulation of cardiac muscle cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cardiac muscle cell proliferation

Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.

Mus musculus
Name Description Probability Func Analog Organism
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 1.000
Shh sonic hedgehog 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Tbx3 T-box 3 1.000
Gli2 GLI-Kruppel family member GLI2 1.000
Hand2 heart and neural crest derivatives expressed transcript 2 0.999
Pax2 paired box gene 2 0.999
Fgf8 fibroblast growth factor 8 0.994
Gata4 GATA binding protein 4 0.992
Fgf10 fibroblast growth factor 10 0.987
Ret ret proto-oncogene 0.987
Pax3 paired box gene 3 0.985
Gli3 GLI-Kruppel family member GLI3 0.980
Notch1 Notch gene homolog 1 (Drosophila) 0.977
Foxc1 forkhead box C1 0.971
Hand1 heart and neural crest derivatives expressed transcript 1 0.970
Pitx2 paired-like homeodomain transcription factor 2 0.970
Hoxa13 homeobox A13 0.968
Bmp4 bone morphogenetic protein 4 0.967
Trp63 transformation related protein 63 0.966
Sox9 SRY-box containing gene 9 0.965
Tbx5 T-box 5 0.954
Hoxd13 homeobox D13 0.938
Zfpm2 zinc finger protein, multitype 2 0.930
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.925
Foxc2 forkhead box C2 0.906
Hoxa1 homeobox A1 0.896
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.881
Pten phosphatase and tensin homolog 0.876
Apc adenomatosis polyposis coli 0.873
Tbx15 T-box 15 0.862
Jag1 jagged 1 0.861
Fgfr3 fibroblast growth factor receptor 3 0.852
Lmx1a LIM homeobox transcription factor 1 alpha 0.839
Ntf3 neurotrophin 3 0.833
Fgfr1 fibroblast growth factor receptor 1 0.825
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.815
Gata6 GATA binding protein 6 0.814
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.801
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.799
Gli1 GLI-Kruppel family member GLI1 0.773
Meox2 mesenchyme homeobox 2 0.764
She src homology 2 domain-containing transforming protein E 0.763
Tbx1 T-box 1 0.759
Pitx1 paired-like homeodomain transcription factor 1 0.745
Efnb2 ephrin B2 0.733
Cdx2 caudal type homeobox 2 0.705
Rxra retinoid X receptor alpha 0.683
Fgf15 fibroblast growth factor 15 0.676
Otx2 orthodenticle homolog 2 (Drosophila) 0.666
Trp53 transformation related protein 53 0.652
Tbx2 T-box 2 0.648
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.633
Nog noggin 0.617
Nodal nodal 0.580
Dll4 delta-like 4 (Drosophila) 0.566
Sox2 SRY-box containing gene 2 0.564
Foxf1a forkhead box F1a 0.557
Hoxa11 homeobox A11 0.553
Hoxd11 homeobox D11 0.550
Btbd17 BTB (POZ) domain containing 17 0.546
Fgf18 fibroblast growth factor 18 0.532
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.522
Pthlh parathyroid hormone-like peptide 0.511
Pou5f1 POU domain, class 5, transcription factor 1 0.500
Smad6 MAD homolog 6 (Drosophila) 0.490
Nos3 nitric oxide synthase 3, endothelial cell 0.489
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.488
Fgf5 fibroblast growth factor 5 0.480
Wt1 Wilms tumor 1 homolog 0.478
Pou3f3 POU domain, class 3, transcription factor 3 0.463
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.434
Gdf5 growth differentiation factor 5 0.434
Zeb1 zinc finger E-box binding homeobox 1 0.424
Twist2 twist homolog 2 (Drosophila) 0.413
Msx2 homeobox, msh-like 2 0.399
Alx4 aristaless-like homeobox 4 0.397
Ctnnb1 catenin (cadherin associated protein), beta 1 0.396
Gbx2 gastrulation brain homeobox 2 0.394
Lhx1 LIM homeobox protein 1 0.389
Smad4 MAD homolog 4 (Drosophila) 0.389
Scn5a sodium channel, voltage-gated, type V, alpha 0.372
Hmx3 H6 homeobox 3 0.369
Wnt2b wingless related MMTV integration site 2b 0.368
Wnt11 wingless-related MMTV integration site 11 0.357
Gata5 GATA binding protein 5 0.353
Barx1 BarH-like homeobox 1 0.350
Dlx5 distal-less homeobox 5 0.334
Vangl2 vang-like 2 (van gogh, Drosophila) 0.333
Phox2b paired-like homeobox 2b 0.326
Gsc goosecoid homeobox 0.319
Nkx2-1 NK2 homeobox 1 0.309
Msx1 homeobox, msh-like 1 0.305
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.304
Pdx1 pancreatic and duodenal homeobox 1 0.294
Foxd3 forkhead box D3 0.290
Rarb retinoic acid receptor, beta 0.288
Acan aggrecan 0.286
Ptf1a pancreas specific transcription factor, 1a 0.285
En1 engrailed 1 0.282
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FGFR2 fibroblast growth factor receptor 2 1.000
FGF1 fibroblast growth factor 1 (acidic) 1.000
CDK2 cyclin-dependent kinase 2 0.999
HDAC1 histone deacetylase 1 0.992
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.987
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.984
FGF10 fibroblast growth factor 10 0.974
KRT5 keratin 5 0.863
TGFB3 transforming growth factor, beta 3 0.817
MAML1 mastermind-like 1 (Drosophila) 0.785
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.761
HDAC4 histone deacetylase 4 0.751
JAG1 jagged 1 0.714
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.701
WWOX WW domain containing oxidoreductase 0.697
FGFR1 fibroblast growth factor receptor 1 0.683
FRS2 fibroblast growth factor receptor substrate 2 0.678
TGFB1 transforming growth factor, beta 1 0.614
SATB2 SATB homeobox 2 0.590
TTR transthyretin 0.581
PLCG1 phospholipase C, gamma 1 0.571
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.566
EGFR epidermal growth factor receptor 0.535
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.514
NOTCH1 notch 1 0.503
CCNE1 cyclin E1 0.490
STK3 serine/threonine kinase 3 0.458
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.452
STK4 serine/threonine kinase 4 0.445
FGF7 fibroblast growth factor 7 0.441
CCNB1 cyclin B1 0.429
CCNA2 cyclin A2 0.417
EP300 E1A binding protein p300 0.392
CABLES1 Cdk5 and Abl enzyme substrate 1 0.389
ATXN1L ataxin 1-like 0.304
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.263
HDAC9 histone deacetylase 9 0.259
YAP1 Yes-associated protein 1 0.258
NOTCH3 notch 3 0.251
ESR1 estrogen receptor 1 0.248
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.233
CCNB2 cyclin B2 0.231
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.210
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.204
TRO trophinin 0.199
FGF2 fibroblast growth factor 2 (basic) 0.195
KLF13 Kruppel-like factor 13 0.193
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.186
RB1 retinoblastoma 1 0.172
SKP2 S-phase kinase-associated protein 2 (p45) 0.169
FGFR3 fibroblast growth factor receptor 3 0.168
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.166
SPEN spen homolog, transcriptional regulator (Drosophila) 0.163
BMP2 bone morphogenetic protein 2 0.162
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.161
ENG endoglin 0.160
NCOR2 nuclear receptor corepressor 2 0.152
FSTL1 follistatin-like 1 0.147
TP53BP2 tumor protein p53 binding protein, 2 0.144
TBX5 T-box 5 0.140
CKS2 CDC28 protein kinase regulatory subunit 2 0.136
DLG2 discs, large homolog 2 (Drosophila) 0.121
MEF2A myocyte enhancer factor 2A 0.113
TNS4 tensin 4 0.110
SEC16A SEC16 homolog A (S. cerevisiae) 0.110
NRP1 neuropilin 1 0.099
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.095
PPP1R13B protein phosphatase 1, regulatory (inhibitor) subunit 13B 0.094
BMP7 bone morphogenetic protein 7 0.088
KRT6C keratin 6C 0.085
GATAD2B GATA zinc finger domain containing 2B 0.085
TP73 tumor protein p73 0.079
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.074
GATA4 GATA binding protein 4 0.073
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.073
CKS1B CDC28 protein kinase regulatory subunit 1B 0.073
NOSTRIN nitric oxide synthase trafficker 0.070
AMOTL1 angiomotin like 1 0.070
TBX1 T-box 1 0.068
GATA5 GATA binding protein 5 0.068
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.066
ABL2 v-abl Abelson murine leukemia viral oncogene homolog 2 0.064
EPAS1 endothelial PAS domain protein 1 0.063
DLG3 discs, large homolog 3 (Drosophila) 0.063
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.062
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.061
FGF8 fibroblast growth factor 8 (androgen-induced) 0.058
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.057
SPTBN1 spectrin, beta, non-erythrocytic 1 0.057
MOBKL1A MOB1, Mps One Binder kinase activator-like 1A (yeast) 0.055
TGFBR1 transforming growth factor, beta receptor 1 0.055
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.055
SNW1 SNW domain containing 1 0.055
S1PR5 sphingosine-1-phosphate receptor 5 0.055
APP amyloid beta (A4) precursor protein 0.053
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.053
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.052
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.052
CIR1 corepressor interacting with RBPJ, 1 0.051
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.051
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Rattus norvegicus
Name Description Probability Func Analog Organism
Top2a topoisomerase (DNA) II alpha 0.222
Pttg1 pituitary tumor-transforming 1 0.033
Smad7 SMAD family member 7 0.032
Kcng2 potassium voltage-gated channel, subfamily G, member 2 0.029
Cks2 CDC28 protein kinase regulatory subunit 2 0.022
Syt8 synaptotagmin VIII 0.021
Prl8a2 prolactin family 8, subfamily a, member 2 0.021
Tgfbr2 transforming growth factor, beta receptor II 0.020
Col4a4 collagen, type IV, alpha 4 0.017
Olr837 olfactory receptor 837 0.013
Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 0.013
Nfia nuclear factor I/A 0.013
Hist1h1d histone cluster 1, H1d 0.013
Notch2 Notch homolog 2 (Drosophila) 0.012
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.012
Ednra endothelin receptor type A 0.011
Mprip myosin phosphatase Rho interacting protein 0.011
Kifc1 kinesin family member C1 0.010
Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.010
Slc10a2 solute carrier family 10 (sodium/bile acid cotransporter family), member 2 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism