The network for 'positive regulation of t helper 1 cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of t helper 1 cell differentiation

Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.

Name Description Probability Func Analog Organism
Ccl2 chemokine (C-C motif) ligand 2 1.000
Ccl12 chemokine (C-C motif) ligand 12 0.994
Ccl3 chemokine (C-C motif) ligand 3 0.992
Batf basic leucine zipper transcription factor, ATF-like 0.976
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.969
Tnf tumor necrosis factor 0.965
Cxcl2 chemokine (C-X-C motif) ligand 2 0.949
Lepr leptin receptor 0.904
Ccl7 chemokine (C-C motif) ligand 7 0.898
Ch25h cholesterol 25-hydroxylase 0.880
Ccl8 chemokine (C-C motif) ligand 8 0.877
Il6 interleukin 6 0.845
Cxcl1 chemokine (C-X-C motif) ligand 1 0.791
Icam1 intercellular adhesion molecule 1 0.769
Ccr1 chemokine (C-C motif) receptor 1 0.733
Ccr2 chemokine (C-C motif) receptor 2 0.704
Ifng interferon gamma 0.697
Fcgr1 Fc receptor, IgG, high affinity I 0.685
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.648
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.630
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.624
Bcl3 B-cell leukemia/lymphoma 3 0.611
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.609
Pdcd1 programmed cell death 1 0.603
Mmp12 matrix metallopeptidase 12 0.596
Lag3 lymphocyte-activation gene 3 0.585
Ccl17 chemokine (C-C motif) ligand 17 0.560
Irg1 immunoresponsive gene 1 0.559
Cd40 CD40 antigen 0.545
Serpina3g serine (or cysteine) peptidase inhibitor, clade A, member 3G 0.543
Il1b interleukin 1 beta 0.540
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.539
Ccl4 chemokine (C-C motif) ligand 4 0.508
Atf3 activating transcription factor 3 0.507
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.501
Socs3 suppressor of cytokine signaling 3 0.486
Cd44 CD44 antigen 0.474
Socs1 suppressor of cytokine signaling 1 0.474
Cxcl9 chemokine (C-X-C motif) ligand 9 0.462
Jak2 Janus kinase 2 0.413
Msr1 macrophage scavenger receptor 1 0.406
Saa3 serum amyloid A 3 0.391
Gdf15 growth differentiation factor 15 0.386
Batf3 basic leucine zipper transcription factor, ATF-like 3 0.381
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.367
Cxcl10 chemokine (C-X-C motif) ligand 10 0.364
Timp1 tissue inhibitor of metalloproteinase 1 0.364
Ubd ubiquitin D 0.360
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.358
Gzma granzyme A 0.354
Ctsw cathepsin W 0.350
Xcl1 chemokine (C motif) ligand 1 0.333
Lcp2 lymphocyte cytosolic protein 2 0.313
Cish cytokine inducible SH2-containing protein 0.310
Clec4d C-type lectin domain family 4, member d 0.307
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.285
Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 0.283
Folr2 folate receptor 2 (fetal) 0.273
Plaur plasminogen activator, urokinase receptor 0.270
Cd14 CD14 antigen 0.269
C3ar1 complement component 3a receptor 1 0.259
Il1rn interleukin 1 receptor antagonist 0.246
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.244
Ccl9 chemokine (C-C motif) ligand 9 0.239
Ccl22 chemokine (C-C motif) ligand 22 0.234
Ccr5 chemokine (C-C motif) receptor 5 0.224
Slfn2 schlafen 2 0.196
Gzmb granzyme B 0.195
Fas Fas (TNF receptor superfamily member 6) 0.194
Stat3 signal transducer and activator of transcription 3 0.187
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.187
Sh2d2a SH2 domain protein 2A 0.187
Batf2 basic leucine zipper transcription factor, ATF-like 2 0.182
Egr2 early growth response 2 0.178
C1qc complement component 1, q subcomponent, C chain 0.174
Mmp3 matrix metallopeptidase 3 0.165
Pitx3 paired-like homeodomain transcription factor 3 0.161
Cd86 CD86 antigen 0.160
Irf5 interferon regulatory factor 5 0.155
Nfkbie nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.152
Itgax integrin alpha X 0.150
Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) 0.149
Ccr7 chemokine (C-C motif) receptor 7 0.147
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.142
Socs2 suppressor of cytokine signaling 2 0.138
Irf1 interferon regulatory factor 1 0.136
Has1 hyaluronan synthase1 0.135
AI607873 expressed sequence AI607873 0.127
Osmr oncostatin M receptor 0.121
Junb Jun-B oncogene 0.119
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.118
Lilrb3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.116
Itgb2 integrin beta 2 0.116
Myd88 myeloid differentiation primary response gene 88 0.113
Il2rb interleukin 2 receptor, beta chain 0.111
Cxcl16 chemokine (C-X-C motif) ligand 16 0.110
Cxcl13 chemokine (C-X-C motif) ligand 13 0.108
Traf2 TNF receptor-associated factor 2 0.105
Selp selectin, platelet 0.099
Rgs1 regulator of G-protein signaling 1 0.099
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism